#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P56945	uniprotkb:Q6ZNL6	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-7962481|ensembl:ENSP00000285046|uniprotkb:Q6MZY1|uniprotkb:Q8N8G4|uniprotkb:Q7Z303|uniprotkb:B3KVQ3|uniprotkb:Q8N861|intact:UNK-5489544|uniprotkb:Q8IYP3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fgd5_human(display_long)|uniprotkb:Zinc finger FYVE domain-containing protein 23(gene name synonym)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000154783(gene)|ensembl:ENST00000285046(transcript)|go:"GO:0001726"(ruffle)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|mint:Q6ZNL6|rcsb pdb:3MPX|reactome:R-HSA-9013149|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005829"(cytosol)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|refseq:NP_689749.3	-	-	comment:mint|comment:homomint|function:May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q8IVF7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-7242231|intact:MINT-1182764|uniprotkb:Q6ZRJ1|uniprotkb:B0JZA7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fmnl3_human(display_long)|uniprotkb:FHOD3(gene name synonym)|uniprotkb:KIAA2014(gene name synonym)|uniprotkb:FMNL3(gene name)|psi-mi:FMNL3(display_short)|uniprotkb:WBP3(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 3(gene name synonym)|uniprotkb:WW domain-binding protein 3(gene name synonym)|uniprotkb:FRL2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	reactome:R-HSA-5663220|interpro:IPR043592|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010473(Diaphanous GTPase-binding)|refseq:NP_783863.4|refseq:NP_944489.2|interpro:IPR015425(Actin-binding FH2)|refseq:XP_005269275.1|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051015"(actin filament binding)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR011989(Armadillo-like helical)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013409|interpro:IPR027655|interpro:IPR042201	-	-	comment:mint|comment:homomint	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:sm2tPWzh9H/+mwiMT73nHTzGx0E9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62258	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UNL2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1043938|uniprotkb:Q549M4|ensembl:ENSP00000265044|uniprotkb:B2R7D0|uniprotkb:D3DNK5|uniprotkb:B4E2P2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ssrg_human(display_long)|uniprotkb:Signal sequence receptor subunit gamma(gene name synonym)|uniprotkb:SSR3(gene name)|psi-mi:SSR3(display_short)|uniprotkb:TRAPG(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_009038.1|ensembl:ENSG00000114850(gene)|ensembl:ENST00000265044(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009779(Translocon-associated, gamma subunit)|mint:Q9UNL2|reactome:R-HSA-1799339|refseq:NP_001295126.1|refseq:NP_001295133.1|refseq:NP_001295134.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Fb918T41oaTpc+kzNIygp1h1tlo9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q01105	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P06454	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O00231	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:BgQKXK7gMMihacRCI+g/pBnRN309606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P55209	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y608	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001127841.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:NP_001269620.1|ensembl:ENSG00000093167(gene)|ensembl:ENST00000336686(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030275"(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:XP_016862973.1|refseq:NP_001335239.1|refseq:NP_001335240.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96AG4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49257	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005561.1|ensembl:ENSG00000074695(gene)|ensembl:ENST00000251047(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033085|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-948021|reactome:R-HSA-9013423|dip:DIP-42188N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P09429	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P02751	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y678	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O43852	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P04083	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P29401	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|ensembl:ENSP00000405455|ensembl:ENSP00000417773|intact:EBI-11110174	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|ensembl:ENSG00000163931(gene)|ensembl:ENST00000423525(transcript)|ensembl:ENST00000462138(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031982"(vesicle)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|reactome:R-HSA-163754|reactome:R-HSA-71336|refseq:XP_011532356.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O43426	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2821539|uniprotkb:O43425|uniprotkb:O94984|uniprotkb:Q4KMR1|ensembl:ENSP00000501426	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:synj1_human(display_long)|uniprotkb:SYNJ1(gene name)|psi-mi:SYNJ1(display_short)|uniprotkb:KIAA0910(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001153774.1|refseq:NP_001153778.1|refseq:NP_003886.3|refseq:NP_982271.2|refseq:XP_016883989.1|ensembl:ENSG00000159082(gene)|ensembl:ENST00000674308(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005874"(microtubule)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034097"(response to cytokine)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:1990175"(EH domain binding)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR034971|interpro:IPR034972|interpro:IPR035979|interpro:IPR036691|mint:O43426|rcsb pdb:1W80|rcsb pdb:2DNR|rcsb pdb:2VJ0|rcsb pdb:7A0V|reactome:R-HSA-1660499|reactome:R-HSA-1855183|reactome:R-HSA-1855204|reactome:R-HSA-8856828	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:RA73eMbCn6F7MD0ItxF/V7QbjqM9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q02978	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P30041	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2255129|uniprotkb:A8JZY7|uniprotkb:P32077|uniprotkb:Q5TAH4|uniprotkb:Q5ZEZ8|ensembl:ENSP00000342026	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prdx6_human(display_long)|uniprotkb:PRDX6(gene name)|psi-mi:PRDX6(display_short)|uniprotkb:AOP2(gene name synonym)|uniprotkb:KIAA0106(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:24 kDa protein(gene name synonym)|uniprotkb:Liver 2D page spot 40(gene name synonym)|uniprotkb:Red blood cells page spot 12(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004896.1|ensembl:ENSG00000117592(gene)|ensembl:ENST00000340385(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:1PRX|rcsb pdb:5B6M|rcsb pdb:5B6N|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0042744"(hydrogen peroxide catabolic process)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ZMsHgrAJf0VJiCELzo+zSi8Ji+49606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07237	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P00338	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P04406	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q16698	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2554876|uniprotkb:B7Z6B8|uniprotkb:Q93085|uniprotkb:Q2M304|ensembl:ENSP00000220764|intact:EBI-10969978	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:decr_human(display_long)|uniprotkb:DECR(gene name synonym)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)|uniprotkb:DECR1(gene name)|psi-mi:DECR1(display_short)|uniprotkb:SDR18C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 18C member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001350.1|ensembl:ENSG00000104325(gene)|ensembl:ENST00000220764(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|mint:Q16698|rcsb pdb:1W6U|rcsb pdb:1W73|rcsb pdb:1W8D|reactome:R-HSA-77288|interpro:IPR036291|refseq:NP_001317504.1|refseq:XP_016868636.1|refseq:XP_016868637.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:l/8jxdd4pqUIUV2eIThvXTd66yE9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P09543	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1059219|intact:EBI-1188262|ensembl:ENSP00000377470	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:cn37_human(display_long)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_149124.3|refseq:XP_011522642.1|ensembl:ENSG00000173786(gene)|ensembl:ENST00000393892(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0045202"(synapse)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P09543|rcsb pdb:1WOJ|go:"GO:0003723"(RNA binding)|refseq:NP_001317145.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TpzVM789s3qQKK7B00Vo92s31bY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P04075	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y305	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2548214|ensembl:ENSP00000336580|uniprotkb:B3KNC9|uniprotkb:B7ZM94	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:acot9_human(display_long)|uniprotkb:ACOT9(gene name)|psi-mi:ACOT9(display_short)|uniprotkb:Acyl-CoA thioester hydrolase 9(gene name synonym)|uniprotkb:CGI-16(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000123130(gene)|ensembl:ENST00000336430(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR029069|interpro:IPR033120|mint:Q9Y305|reactome:R-HSA-77289|refseq:NP_001028755.2|refseq:NP_001032248.1|refseq:NP_001317188.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:WbPOPMGV/9XQRxLufTKCXvYQH/Y9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P05387	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P18124	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P46777	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62891	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q59GN2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-10101575	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:r39l5_human(display_long)|uniprotkb:RPL39P5(gene name)|psi-mi:RPL39P5(display_short)|uniprotkb:60S ribosomal protein L39 pseudogene 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR023626|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:vqUrMKZ0TgDiCZbYR2+EBEZS8QY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61353	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q6ZNG9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-13309813|ensembl:ENSP00000494883|uniprotkb:Q8IYY0	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:krba2_human(display_long)|uniprotkb:KRBA2(gene name)|psi-mi:KRBA2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000184619(gene)|ensembl:ENST00000643221(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0015074"(DNA integration)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036051|interpro:IPR036397|refseq:NP_001291876.1|refseq:NP_998762.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:pfVTsBaFoCQbwChKch6i+EBzggA9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61254	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352405|uniprotkb:Q02877|uniprotkb:Q6IPY2|uniprotkb:B2R4F0|uniprotkb:D3DTR8|ensembl:ENSP00000462322|ensembl:ENSP00000463470|ensembl:ENSP00000463784|ensembl:ENSP00000498177	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl26_human(display_long)|uniprotkb:RPL26(gene name)|psi-mi:RPL26(display_short)|uniprotkb:Large ribosomal subunit protein uL24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000978.1|refseq:NP_001302459.1|refseq:NP_001302460.1|ensembl:ENST00000582556(transcript)|ensembl:ENST00000583011(transcript)|ensembl:ENST00000584164(transcript)|ensembl:ENST00000648839(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|ensembl:ENSG00000161970(gene)|go:"GO:0022626"(cytosolic ribosome)|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904803"(regulation of translation involved in cellular response to UV)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:P61254|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|go:"GO:0034644"(cellular response to UV)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:5LKS|reactome:R-HSA-156827|dip:DIP-33198N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:VAROWOFmYvolVgc/e5E1jAmNuaY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P40429	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-720205|uniprotkb:A8K505|ensembl:ENSP00000375730	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl13a_human(display_long)|uniprotkb:23 kDa highly basic protein(gene name synonym)|uniprotkb:RPL13A(gene name)|psi-mi:RPL13A(display_short)|uniprotkb:Large ribosomal subunit protein uL13(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_036555.1|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6OLF|ensembl:ENSG00000142541(gene)|ensembl:ENST00000391857(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1901194"(negative regulation of formation of translation preinitiation complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR023563|interpro:IPR036899|mint:P40429|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|refseq:NP_001257420.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:pcKDTEBZXxtm1MAH+4nv0p3PqFs9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62906	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q04637	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O00303	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q7Z478	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-719925|uniprotkb:O75549|uniprotkb:Q63HN0|uniprotkb:Q63HN3|uniprotkb:Q8IWW2|uniprotkb:Q8N3A1|uniprotkb:Q9UMH2|intact:EBI-28967230|ensembl:ENSP00000251636	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dhx29_human(display_long)|uniprotkb:DEAH box protein 29(gene name synonym)|uniprotkb:Nucleic acid helicase DDXx(gene name synonym)|uniprotkb:DHX29(gene name)|psi-mi:DHX29(display_short)|uniprotkb:DDX29(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSP00000251636|refseq:NP_061903.2|ensembl:ENSG00000067248(gene)|ensembl:ENST00000251636(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR034730|refseq:NP_001332893.1|refseq:NP_001332894.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:T78lwkAmdyEefThCR1zDrVbTBYE9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q00059	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96AQ6	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UPE1	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-6381269|ensembl:ENSP00000359119|uniprotkb:Q13583|uniprotkb:Q4F970|uniprotkb:Q562F5|uniprotkb:Q9UM62	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:srpk3_human(display_long)|uniprotkb:SRPK3(gene name)|psi-mi:SRPK3(display_short)|uniprotkb:MSSK1(gene name synonym)|uniprotkb:STK23(gene name synonym)|uniprotkb:Muscle-specific serine kinase 1(gene name synonym)|uniprotkb:Serine/arginine-rich protein-specific kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000184343(gene)|ensembl:ENST00000370101(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060537"(muscle tissue development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001164231.1|refseq:NP_001164232.1|refseq:NP_055185.2	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:6ql5aVjg33WfG4PJx2UcalNmebY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P78362	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-593303|uniprotkb:A8MVX2|uniprotkb:O75220|uniprotkb:O75221|uniprotkb:Q6NUL0|uniprotkb:Q6V1X2|uniprotkb:Q8IYQ3|ensembl:ENSP00000349863|ensembl:ENSP00000419791	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:srpk2_human(display_long)|uniprotkb:Serine/arginine-rich protein-specific kinase 2(gene name synonym)|uniprotkb:SFRS protein kinase 2(gene name synonym)|uniprotkb:SRPK2(gene name)|psi-mi:SRPK2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_872633.1|refseq:NP_872634.1|refseq:NP_001265202.1|refseq:XP_016868055.1|ensembl:ENSG00000135250(gene)|ensembl:ENST00000357311(transcript)|ensembl:ENST00000489828(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2X7G|rcsb pdb:5MYV	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:dwIEunDCbmP7D/TZsXuoywX6o8U9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96SB4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-539478|uniprotkb:Q12890|uniprotkb:Q5R364|uniprotkb:Q5R365|uniprotkb:Q8IY12|uniprotkb:B4DS61|ensembl:ENSP00000362931	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:srpk1_human(display_long)|uniprotkb:Serine/arginine-rich protein-specific kinase 1(gene name synonym)|uniprotkb:SFRS protein kinase 1(gene name synonym)|uniprotkb:SRPK1(gene name)|psi-mi:SRPK1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003128.3|ensembl:ENSG00000096063(gene)|ensembl:ENST00000373825(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q96SB4|rcsb pdb:1WAK|rcsb pdb:1WBP|rcsb pdb:3BEG|rcsb pdb:4WUA|rcsb pdb:5MXX|rcsb pdb:5MY8|rcsb pdb:5NNG|rcsb pdb:5XV7|rcsb pdb:6FAD|rcsb pdb:7DD1|dip:DIP-33888N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:e335v+Im7IjFP1CdFzPefvU8iQo9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49591	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1053431|uniprotkb:Q5T5C8|uniprotkb:Q9NSE3|uniprotkb:B2R6Y9|ensembl:ENSP00000234677	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sysc_human(display_long)|uniprotkb:SARS1(gene name)|psi-mi:SARS1(display_short)|uniprotkb:SARS(gene name synonym)|uniprotkb:SERS(gene name synonym)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006504.2|ensembl:ENSG00000031698(gene)|ensembl:ENST00000234677(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019899"(enzyme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR033729|interpro:IPR042103|rcsb pdb:3VBB|rcsb pdb:4L87|rcsb pdb:4RQE|rcsb pdb:4RQF|reactome:R-HSA-2408557|reactome:R-HSA-379716|dip:DIP-38215N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:4+Ai/MIybmiKJyfa0C0bhnW/CG49606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96PU8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9H361	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1055272|uniprotkb:Q8NHV0|uniprotkb:Q9H086|ensembl:ENSP00000281589	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pabp3_human(display_long)|uniprotkb:"Testis-specific poly(A)-binding protein"(gene name synonym)|uniprotkb:PABPC3(gene name)|psi-mi:PABPC3(display_short)|uniprotkb:PABP3(gene name synonym)|uniprotkb:PABPL3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112241.2|ensembl:ENSG00000151846(gene)|ensembl:ENST00000281589(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q9H361|rcsb pdb:2D9P|rcsb pdb:4IVE	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:g/tDJDBcBC+s8P6LGDIwgZO8HHY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P11940	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P19338	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07814	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UDY4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356960|uniprotkb:Q13431|uniprotkb:B2R824|ensembl:ENSP00000359799	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dnjb4_human(display_long)|uniprotkb:DNAJB4(gene name)|psi-mi:DNAJB4(display_short)|uniprotkb:DNAJW(gene name synonym)|uniprotkb:HLJ1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1 homolog(gene name synonym)|uniprotkb:Human liver DnaJ-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_008965.2|refseq:NP_001304028.1|refseq:NP_001304029.1|refseq:NP_001304030.1|refseq:NP_001304031.1|refseq:NP_001304032.1|ensembl:ENSG00000162616(gene)|ensembl:ENST00000370763(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UDY4	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:gN0zBtJQiTN+YYSAtMk1mddNWLU9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P31689	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UL54	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352832|ensembl:ENSP00000310094|uniprotkb:O94957|uniprotkb:Q6UW73|uniprotkb:Q7LC09|uniprotkb:Q9NSW2|uniprotkb:B2RN35|uniprotkb:A5PKY1|uniprotkb:A7MCZ2|uniprotkb:B7ZM88	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:taok2_human(display_long)|uniprotkb:TAOK2(gene name)|psi-mi:TAOK2(display_short)|uniprotkb:KIAA0881(gene name synonym)|uniprotkb:MAP3K17(gene name synonym)|uniprotkb:PSK(gene name synonym)|uniprotkb:PSK1(gene name synonym)|uniprotkb:UNQ2971/PRO7431(orf name)|uniprotkb:Prostate-derived sterile 20-like kinase 1(gene name synonym)|uniprotkb:Thousand and one amino acid protein kinase 2(gene name synonym)|uniprotkb:Kinase from chicken homolog C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038191"(neuropilin binding)|go:"GO:0007409"(axonogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0048156"(tau protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0106311"|go:"GO:0150019"(basal dendrite morphogenesis)|go:"GO:0150020"(basal dendrite arborization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0044295"(axonal growth cone)|mint:Q9UL54|go:"GO:0046330"(positive regulation of JNK cascade)|ensembl:ENSG00000149930(gene)|ensembl:ENST00000308893(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|refseq:NP_004774.1|refseq:NP_057235.2|refseq:NP_001238972.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:aA9reWZMb8l6Ziy+jyX5bbTD6vE9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62136	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O15355	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96JC1	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1050197|uniprotkb:O94869|uniprotkb:Q7Z3V3|uniprotkb:Q96B93|uniprotkb:Q96RM0|uniprotkb:Q71SQ6|ensembl:ENSP00000335193	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:vps39_human(display_long)|uniprotkb:KIAA0770(gene name synonym)|uniprotkb:VPS39(gene name)|psi-mi:VPS39(display_short)|uniprotkb:VAM6(gene name synonym)|uniprotkb:TLP(gene name synonym)|uniprotkb:TRAP1-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_056104.2|refseq:NP_001288067.1|ensembl:ENSG00000166887(gene)|ensembl:ENST00000348544(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001180(Citron-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|rcsb pdb:6ZE9	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:BeY8ZDCOyTvZqA0WpdWnmz+giYk9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9H115	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-3921185|ensembl:ENSP00000366225|uniprotkb:Q4G187|uniprotkb:Q5JXF9|uniprotkb:Q8N3C4|uniprotkb:B4DK44|uniprotkb:Q4G0M0	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:snab_human(display_long)|uniprotkb:NAPB(gene name)|psi-mi:NAPB(display_short)|uniprotkb:SNAPB(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000125814(gene)|ensembl:ENST00000377026(transcript)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_071363.1|refseq:NP_001269947.1|refseq:NP_001269949.1|refseq:NP_001269955.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:tKGtS2Dzj2CNItyIHAI2LOIiGyU9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P54920	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P18085	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1237085|ensembl:ENSP00000306010|uniprotkb:P21371|uniprotkb:B2R7J7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:arf4_human(display_long)|uniprotkb:ARF4(gene name)|psi-mi:ARF4(display_short)|uniprotkb:ARF2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000168374(gene)|ensembl:ENST00000303436(transcript)|refseq:NP_001651.1|dip:DIP-38214N|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0060271"(cilium assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P18085|rcsb pdb:1Z6X|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AN3aBuSStAMrmkqq1HEDQtOiCy49606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P53680	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-297662|ensembl:ENSP00000263270|uniprotkb:O75977|uniprotkb:Q6PK67|uniprotkb:B2R4Z4	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ap2s1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit sigma(gene name synonym)|uniprotkb:AP2S1(gene name)|psi-mi:AP2S1(display_short)|uniprotkb:Sigma2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 17 kDa protein(gene name synonym)|uniprotkb:HA2 17 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP17(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP17(gene name synonym)|uniprotkb:AP17(gene name synonym)|uniprotkb:CLAPS2(gene name synonym)|uniprotkb:Clathrin assembly protein 2 sigma small chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit sigma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000042753(gene)|ensembl:ENST00000263270(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027156|rcsb pdb:6URI|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004060.2|refseq:NP_067586.1|refseq:NP_001288005.1|refseq:NP_001288007.1|refseq:NP_001288010.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AJxHeeoCpwPxjsRcAQkiAGaC9k09606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P63313	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2688673|uniprotkb:Q596K9|uniprotkb:P13472|ensembl:ENSP00000233143	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tyb10_human(display_long)|uniprotkb:PTMB10(gene name synonym)|uniprotkb:THYB10(gene name synonym)|uniprotkb:TMSB10(gene name)|psi-mi:TMSB10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_066926.1|ensembl:ENSG00000034510(gene)|ensembl:ENST00000233143(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042989"(sequestering of actin monomers)|interpro:IPR001152(Thymosin beta-4)|interpro:IPR038386	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:oyHgjBTa5Wd0RSnF3dTUPsgPV9w9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q7Z6B7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2481729|uniprotkb:Q9H8A3|uniprotkb:Q9P2P2|ensembl:ENSP00000347198	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:srgp1_human(display_long)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0030336"(negative regulation of cell migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|go:"GO:0005737"(cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|interpro:IPR037451|mint:Q7Z6B7|reactome:R-HSA-428543|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_065813.1|refseq:NP_001333130.1|dip:DIP-53826N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49006	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-4289961|uniprotkb:Q5TEE6|uniprotkb:Q6NXS5|uniprotkb:D3DPQ0|ensembl:ENSP00000362638	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mrp_human(display_long)|uniprotkb:MARCKSL1(gene name)|psi-mi:MARCKSL1(display_short)|uniprotkb:MLP(gene name synonym)|uniprotkb:MRP(gene name synonym)|uniprotkb:MARCKS-like protein 1(gene name synonym)|uniprotkb:Macrophage myristoylated alanine-rich C kinase substrate(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000175130(gene)|ensembl:ENST00000329421(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P49006|refseq:NP_075385.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:nkq8hGJINvCHlZJ3alKkDP+wCxk9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P21291	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-3959636|uniprotkb:A8K268|uniprotkb:Q5U0J2|ensembl:ENSP00000345079|ensembl:ENSP00000356275|ensembl:ENSP00000434147|ensembl:ENSP00000436792	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:csrp1_human(display_long)|uniprotkb:CSRP1(gene name)|psi-mi:CSRP1(display_short)|uniprotkb:CSRP(gene name synonym)|uniprotkb:CYRP(gene name synonym)|uniprotkb:Cysteine-rich protein 1(gene name synonym)|uniprotkb:Epididymis luminal protein 141(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001180499.1|refseq:NP_001180500.1|refseq:NP_001180501.1|refseq:NP_004069.1|ensembl:ENSG00000159176(gene)|ensembl:ENST00000367306(transcript)|ensembl:ENST00000532460(transcript)|ensembl:ENST00000533432(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-HSA-5660489|ensembl:ENST00000340006(transcript)	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:7mB03gFR0px7OTsYWr2F1XD0U209606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y5S2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1043430|uniprotkb:Q2L7A5|uniprotkb:Q86TJ1|uniprotkb:Q9ULU5|ensembl:ENSP00000355237|uniprotkb:A9JR72	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mrckb_human(display_long)|uniprotkb:CDC42-binding protein kinase beta(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase beta(gene name synonym)|uniprotkb:DMPK-like beta(gene name synonym)|uniprotkb:CDC42BPB(gene name)|psi-mi:CDC42BPB(display_short)|uniprotkb:KIAA1124(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000198752(gene)|ensembl:ENST00000361246(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR031597|interpro:IPR033232|interpro:IPR042718|rcsb pdb:3QFV|rcsb pdb:3TKU|rcsb pdb:4UAK|rcsb pdb:4UAL|rcsb pdb:5OTE|rcsb pdb:5OTF|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|refseq:NP_006026.3	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:FaheT9htZ/NtYfTKvNDcLqNtQiQ9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62328	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-712598|uniprotkb:P01253|uniprotkb:P01254|uniprotkb:Q546P5|ensembl:ENSP00000370007|ensembl:ENSP00000370009|ensembl:ENSP00000370010|ensembl:ENSP00000414376|uniprotkb:Q63576|uniprotkb:Q9UE55	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tyb4_human(display_long)|uniprotkb:Fx(gene name synonym)|uniprotkb:TMSB4X(gene name)|psi-mi:TMSB4X(display_short)|uniprotkb:TB4X(gene name synonym)|uniprotkb:THYB4(gene name synonym)|uniprotkb:TMSB4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000205542(gene)|ensembl:ENST00000380633(transcript)|go:"GO:0019899"(enzyme binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|ensembl:ENST00000380635(transcript)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|ensembl:ENST00000380636(transcript)|go:"GO:0042989"(sequestering of actin monomers)|ensembl:ENST00000451311(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905273"(positive regulation of proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001152(Thymosin beta-4)|go:"GO:0005737"(cytoplasm)|interpro:IPR038386|mint:P62328|rcsb pdb:1UY5|go:"GO:0005829"(cytosol)|rcsb pdb:3TU5|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|rcsb pdb:4PL8|rcsb pdb:4PL7|reactome:R-HSA-114608|refseq:NP_066932.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xkqTI8zw7X+xH6HCvkuLtGlNbvs9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07737	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9BPX5	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-711189|ensembl:ENSP00000259477|ensembl:ENSP00000345361|uniprotkb:Q7Z523	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:arp5l_human(display_long)|uniprotkb:Arp2/3 complex 16 kDa subunit 2(gene name synonym)|uniprotkb:ARPC5L(gene name)|psi-mi:ARPC5L(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112240.1|ensembl:ENSG00000136950(gene)|ensembl:ENST00000259477(transcript)|ensembl:ENST00000353214(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0016477"(cell migration)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR030075|interpro:IPR036743|mint:Q9BPX5|rcsb pdb:6YW6|dip:DIP-50399N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:JVproBu8rIrnlk39yXPC+ZrvoOk9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P63261	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9BQE3	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1103245|ensembl:ENSP00000301072	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9NYL9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352614|ensembl:ENSP00000308753|uniprotkb:Q9NT43|uniprotkb:Q9NZR0|uniprotkb:B2R6G7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tmod3_human(display_long)|uniprotkb:TMOD3(gene name)|psi-mi:TMOD3(display_short)|uniprotkb:Ubiquitous tropomodulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000138594(gene)|ensembl:ENST00000308580(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|refseq:NP_055362.1|go:"GO:0048821"(erythrocyte development)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR004934(Tropomodulin)|interpro:IPR030133|interpro:IPR032675|mint:Q9NYL9|reactome:R-HSA-390522|reactome:R-HSA-9013418|reactome:R-HSA-9696264|refseq:XP_016877576.1|refseq:XP_016877577.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:crEfCAAepSPAE8ByBpD4Sr14P5I9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O75347	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2686341|uniprotkb:B4DT30|ensembl:ENSP00000369736	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tbca_human(display_long)|uniprotkb:TCP1-chaperonin cofactor A(gene name synonym)|uniprotkb:Tubulin-folding cofactor A(gene name synonym)|uniprotkb:TBCA(gene name)|psi-mi:TBCA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004598.1|refseq:NP_001284667.1|ensembl:ENSG00000171530(gene)|ensembl:ENST00000380377(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004226(Tubulin binding cofactor A)|interpro:IPR036126|mint:O75347|rcsb pdb:1H7C|reactome:R-HSA-389977	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:hETmNl4lTAEyZ89oOKuhkah5vmQ9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UM54	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P35749	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1052928|uniprotkb:O00396|uniprotkb:O94944|uniprotkb:P78422|uniprotkb:Q3MNF0|uniprotkb:Q3MNF1|uniprotkb:Q3MIV8|uniprotkb:D2JYH7|ensembl:ENSP00000300036|ensembl:ENSP00000488461	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:myh11_human(display_long)|uniprotkb:Myosin heavy chain 11(gene name synonym)|uniprotkb:Myosin heavy chain, smooth muscle isoform(gene name synonym)|uniprotkb:SMMHC(gene name synonym)|uniprotkb:MYH11(gene name)|psi-mi:MYH11(display_short)|uniprotkb:KIAA0866(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099384|imex:IM-25792-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	dip:DIP-47268N|refseq:NP_002465.1|refseq:NP_001035202.1|refseq:NP_001035203.1|refseq:NP_074035.1|ensembl:ENSG00000133392(gene)|ensembl:ENSG00000276480(gene)|ensembl:ENST00000300036(transcript)|ensembl:ENST00000634050(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0032982"(myosin filament)|go:"GO:0042470"(melanosome)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35749|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016878739.1	-	-	-	stimulant:Interactome post VEFEG stimulation|figure legend:Supplenmetary table 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2019/10/18	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:iE4qZJHXiIfxtk9An/7T4DKbwIU9606	rigid:8zmbHNBfqrSZAnBPVu/RzH2SWmk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UKV8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UL18	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-527363|uniprotkb:Q5TA57|uniprotkb:Q6P4S0|ensembl:ENSP00000362300|ensembl:ENSP00000501450	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ago1_human(display_long)|uniprotkb:AGO1(gene name)|psi-mi:AGO1(display_short)|uniprotkb:Argonaute RISC catalytic component 1(gene name synonym)|uniprotkb:EIF2C1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 1(gene name synonym)|uniprotkb:Putative RNA-binding protein Q99(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	dip:DIP-29193N|refseq:NP_036331.1|ensembl:ENSG00000092847(gene)|ensembl:ENST00000373204(transcript)|ensembl:ENST00000674304(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016442"(RISC complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UL18|rcsb pdb:1SI2|rcsb pdb:1SI3|rcsb pdb:4KRE|rcsb pdb:4KRF|rcsb pdb:4KXT|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|refseq:NP_001304051.1|refseq:NP_001304052.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:l/WmIsnfJjifEOoxOyG9zDo2ljQ9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q6ZNL6	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-7962481|ensembl:ENSP00000285046|uniprotkb:Q6MZY1|uniprotkb:Q8N8G4|uniprotkb:Q7Z303|uniprotkb:B3KVQ3|uniprotkb:Q8N861|intact:UNK-5489544|uniprotkb:Q8IYP3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fgd5_human(display_long)|uniprotkb:Zinc finger FYVE domain-containing protein 23(gene name synonym)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000154783(gene)|ensembl:ENST00000285046(transcript)|go:"GO:0001726"(ruffle)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|mint:Q6ZNL6|rcsb pdb:3MPX|reactome:R-HSA-9013149|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005829"(cytosol)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|refseq:NP_689749.3	-	-	comment:mint|comment:homomint|function:May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q8IVF7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-7242231|intact:MINT-1182764|uniprotkb:Q6ZRJ1|uniprotkb:B0JZA7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fmnl3_human(display_long)|uniprotkb:FHOD3(gene name synonym)|uniprotkb:KIAA2014(gene name synonym)|uniprotkb:FMNL3(gene name)|psi-mi:FMNL3(display_short)|uniprotkb:WBP3(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 3(gene name synonym)|uniprotkb:WW domain-binding protein 3(gene name synonym)|uniprotkb:FRL2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	reactome:R-HSA-5663220|interpro:IPR043592|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010473(Diaphanous GTPase-binding)|refseq:NP_783863.4|refseq:NP_944489.2|interpro:IPR015425(Actin-binding FH2)|refseq:XP_005269275.1|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051015"(actin filament binding)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR011989(Armadillo-like helical)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013409|interpro:IPR027655|interpro:IPR042201	-	-	comment:mint|comment:homomint	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:sm2tPWzh9H/+mwiMT73nHTzGx0E9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P06454	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O00231	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:BgQKXK7gMMihacRCI+g/pBnRN309606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P55209	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y608	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001127841.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:NP_001269620.1|ensembl:ENSG00000093167(gene)|ensembl:ENST00000336686(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030275"(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:XP_016862973.1|refseq:NP_001335239.1|refseq:NP_001335240.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49257	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005561.1|ensembl:ENSG00000074695(gene)|ensembl:ENST00000251047(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033085|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-948021|reactome:R-HSA-9013423|dip:DIP-42188N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P35613	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q8N3C0	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P04083	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response)	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P29401	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|ensembl:ENSP00000405455|ensembl:ENSP00000417773|intact:EBI-11110174	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|ensembl:ENSG00000163931(gene)|ensembl:ENST00000423525(transcript)|ensembl:ENST00000462138(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031982"(vesicle)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|reactome:R-HSA-163754|reactome:R-HSA-71336|refseq:XP_011532356.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P52209	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-372761|uniprotkb:Q9BWD8|intact:EBI-11020895|uniprotkb:A8K2Y9|ensembl:ENSP00000270776|uniprotkb:B4DQJ8	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:6pgd_human(display_long)|uniprotkb:PGD(gene name)|psi-mi:PGD(display_short)|uniprotkb:PGDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001291380.1|refseq:NP_001291381.1|refseq:NP_002622.2|ensembl:ENSG00000142657(gene)|ensembl:ENST00000270776(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|mint:P52209|rcsb pdb:2JKV|rcsb pdb:4GWG|rcsb pdb:4GWK|rcsb pdb:5UQ9|reactome:R-HSA-71336|interpro:IPR036291	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:SgbOgCLmdWm3QnN6fQfkHG6iunw9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P00338	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O60762	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:znbNDwp7t238ByanlbQzsTMvwTY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q16698	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2554876|uniprotkb:B7Z6B8|uniprotkb:Q93085|uniprotkb:Q2M304|ensembl:ENSP00000220764|intact:EBI-10969978	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:decr_human(display_long)|uniprotkb:DECR(gene name synonym)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)|uniprotkb:DECR1(gene name)|psi-mi:DECR1(display_short)|uniprotkb:SDR18C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 18C member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001350.1|ensembl:ENSG00000104325(gene)|ensembl:ENST00000220764(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|mint:Q16698|rcsb pdb:1W6U|rcsb pdb:1W73|rcsb pdb:1W8D|reactome:R-HSA-77288|interpro:IPR036291|refseq:NP_001317504.1|refseq:XP_016868636.1|refseq:XP_016868637.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:l/8jxdd4pqUIUV2eIThvXTd66yE9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P04075	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y305	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2548214|ensembl:ENSP00000336580|uniprotkb:B3KNC9|uniprotkb:B7ZM94	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:acot9_human(display_long)|uniprotkb:ACOT9(gene name)|psi-mi:ACOT9(display_short)|uniprotkb:Acyl-CoA thioester hydrolase 9(gene name synonym)|uniprotkb:CGI-16(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000123130(gene)|ensembl:ENST00000336430(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR029069|interpro:IPR033120|mint:Q9Y305|reactome:R-HSA-77289|refseq:NP_001028755.2|refseq:NP_001032248.1|refseq:NP_001317188.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:WbPOPMGV/9XQRxLufTKCXvYQH/Y9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62280	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P05387	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P18124	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P46777	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61353	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q6ZNG9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-13309813|ensembl:ENSP00000494883|uniprotkb:Q8IYY0	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:krba2_human(display_long)|uniprotkb:KRBA2(gene name)|psi-mi:KRBA2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000184619(gene)|ensembl:ENST00000643221(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0015074"(DNA integration)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036051|interpro:IPR036397|refseq:NP_001291876.1|refseq:NP_998762.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:pfVTsBaFoCQbwChKch6i+EBzggA9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61254	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352405|uniprotkb:Q02877|uniprotkb:Q6IPY2|uniprotkb:B2R4F0|uniprotkb:D3DTR8|ensembl:ENSP00000462322|ensembl:ENSP00000463470|ensembl:ENSP00000463784|ensembl:ENSP00000498177	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl26_human(display_long)|uniprotkb:RPL26(gene name)|psi-mi:RPL26(display_short)|uniprotkb:Large ribosomal subunit protein uL24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000978.1|refseq:NP_001302459.1|refseq:NP_001302460.1|ensembl:ENST00000582556(transcript)|ensembl:ENST00000583011(transcript)|ensembl:ENST00000584164(transcript)|ensembl:ENST00000648839(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|ensembl:ENSG00000161970(gene)|go:"GO:0022626"(cytosolic ribosome)|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904803"(regulation of translation involved in cellular response to UV)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:P61254|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|go:"GO:0034644"(cellular response to UV)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:5LKS|reactome:R-HSA-156827|dip:DIP-33198N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:VAROWOFmYvolVgc/e5E1jAmNuaY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P40429	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-720205|uniprotkb:A8K505|ensembl:ENSP00000375730	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl13a_human(display_long)|uniprotkb:23 kDa highly basic protein(gene name synonym)|uniprotkb:RPL13A(gene name)|psi-mi:RPL13A(display_short)|uniprotkb:Large ribosomal subunit protein uL13(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_036555.1|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6OLF|ensembl:ENSG00000142541(gene)|ensembl:ENST00000391857(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1901194"(negative regulation of formation of translation preinitiation complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR023563|interpro:IPR036899|mint:P40429|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|refseq:NP_001257420.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:pcKDTEBZXxtm1MAH+4nv0p3PqFs9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62906	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q04637	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O15372	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-709735|ensembl:ENSP00000429931	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q00059	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding)	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96AQ6	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9H361	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1055272|uniprotkb:Q8NHV0|uniprotkb:Q9H086|ensembl:ENSP00000281589	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pabp3_human(display_long)|uniprotkb:"Testis-specific poly(A)-binding protein"(gene name synonym)|uniprotkb:PABPC3(gene name)|psi-mi:PABPC3(display_short)|uniprotkb:PABP3(gene name synonym)|uniprotkb:PABPL3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112241.2|ensembl:ENSG00000151846(gene)|ensembl:ENST00000281589(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q9H361|rcsb pdb:2D9P|rcsb pdb:4IVE	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:g/tDJDBcBC+s8P6LGDIwgZO8HHY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P11940	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P19338	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07814	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9HCK5	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2269696|uniprotkb:A7MD27|ensembl:ENSP00000362306	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ago4_human(display_long)|uniprotkb:AGO4(gene name)|psi-mi:AGO4(display_short)|uniprotkb:Argonaute RISC catalytic component 4(gene name synonym)|uniprotkb:EIF2C4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 4(gene name synonym)|uniprotkb:KIAA1567(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_060099.2|ensembl:ENSG00000134698(gene)|ensembl:ENST00000373210(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070578"(RISC-loading complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028604|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|rcsb pdb:6OON|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Trb+nRiEAUNwHDgrcv70Uz20YDs9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9H9G7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2267883|uniprotkb:Q5TA55|uniprotkb:Q9H1U6|uniprotkb:B1ALI0|ensembl:ENSP00000362287	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ago3_human(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:Argonaute RISC catalytic component 3(gene name synonym)|uniprotkb:EIF2C3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:XP_011539184.1|refseq:XP_016856012.1|refseq:XP_016856013.1|refseq:XP_016856014.1|refseq:XP_016856015.1|refseq:XP_016856016.1|refseq:NP_079128.2|refseq:NP_803171.1|refseq:XP_005270632.1|dip:DIP-54486N|ensembl:ENSG00000126070(gene)|ensembl:ENST00000373191(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028603|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9H9G7|rcsb pdb:5VM9|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|go:"GO:0003725"(double-stranded RNA binding)	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:eR/DTdNkUtDVQ4/Nx3Xt2pEfVYU9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P31948	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y4L1	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1054186|uniprotkb:Q2I204|uniprotkb:Q53H25|uniprotkb:B7Z909|uniprotkb:A8C1Z0|ensembl:ENSP00000480150|ensembl:ENSP00000486825	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:hyou1_human(display_long)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)|uniprotkb:GRP170(gene name synonym)|uniprotkb:HYOU1(gene name)|psi-mi:HYOU1(display_short)|uniprotkb:ORP150(gene name synonym)|uniprotkb:170 kDa glucose-regulated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001124463.1|refseq:NP_006380.1|refseq:XP_016872585.1|refseq:XP_016872586.1|ensembl:ENSG00000149428(gene)|ensembl:ENSG00000280682(gene)|ensembl:ENST00000617285(transcript)|ensembl:ENST00000630669(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q9Y4L1|reactome:R-HSA-3000484|reactome:R-HSA-381038|go:"GO:0005790"(smooth endoplasmic reticulum)	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xqSFRaiiHJLNVqgh87tHx9lfnS49606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q58FF8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2961708	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:h90b2_human(display_long)|uniprotkb:HSP90AB2P(gene name)|psi-mi:HSP90AB2P(display_short)|uniprotkb:HSP90BB(gene name synonym)|uniprotkb:Heat shock protein 90-beta b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:SntF/u+V170yoKZScA9O/5BL3Ps9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07900	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UDY4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356960|uniprotkb:Q13431|uniprotkb:B2R824|ensembl:ENSP00000359799	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dnjb4_human(display_long)|uniprotkb:DNAJB4(gene name)|psi-mi:DNAJB4(display_short)|uniprotkb:DNAJW(gene name synonym)|uniprotkb:HLJ1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1 homolog(gene name synonym)|uniprotkb:Human liver DnaJ-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_008965.2|refseq:NP_001304028.1|refseq:NP_001304029.1|refseq:NP_001304030.1|refseq:NP_001304031.1|refseq:NP_001304032.1|ensembl:ENSG00000162616(gene)|ensembl:ENST00000370763(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UDY4	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:gN0zBtJQiTN+YYSAtMk1mddNWLU9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q99832	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UL54	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352832|ensembl:ENSP00000310094|uniprotkb:O94957|uniprotkb:Q6UW73|uniprotkb:Q7LC09|uniprotkb:Q9NSW2|uniprotkb:B2RN35|uniprotkb:A5PKY1|uniprotkb:A7MCZ2|uniprotkb:B7ZM88	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:taok2_human(display_long)|uniprotkb:TAOK2(gene name)|psi-mi:TAOK2(display_short)|uniprotkb:KIAA0881(gene name synonym)|uniprotkb:MAP3K17(gene name synonym)|uniprotkb:PSK(gene name synonym)|uniprotkb:PSK1(gene name synonym)|uniprotkb:UNQ2971/PRO7431(orf name)|uniprotkb:Prostate-derived sterile 20-like kinase 1(gene name synonym)|uniprotkb:Thousand and one amino acid protein kinase 2(gene name synonym)|uniprotkb:Kinase from chicken homolog C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038191"(neuropilin binding)|go:"GO:0007409"(axonogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0048156"(tau protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0106311"|go:"GO:0150019"(basal dendrite morphogenesis)|go:"GO:0150020"(basal dendrite arborization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0044295"(axonal growth cone)|mint:Q9UL54|go:"GO:0046330"(positive regulation of JNK cascade)|ensembl:ENSG00000149930(gene)|ensembl:ENST00000308893(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|refseq:NP_004774.1|refseq:NP_057235.2|refseq:NP_001238972.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:aA9reWZMb8l6Ziy+jyX5bbTD6vE9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q15293	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-948278|ensembl:ENSP00000054950|uniprotkb:D3DR00|uniprotkb:B7Z1M1	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rcn1_human(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:RCN(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	reactome:R-HSA-8957275|reactome:R-HSA-381426|ensembl:ENSG00000049449(gene)|ensembl:ENST00000054950(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q15293|refseq:NP_002892.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ynhvrXX2fQ7Dn1LT+mp2PKm0bc89606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62714	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P67775	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O15355	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O75569	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:tZfziopZlC+1d3De97G3kDY+Tog9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q5VU43	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O14976	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-714707|uniprotkb:Q9BVY6|uniprotkb:Q5U4P5|intact:EBI-28970318|ensembl:ENSP00000314499	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:gak_human(display_long)|uniprotkb:GAK(gene name)|psi-mi:GAK(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSP00000314499|ensembl:ENST00000511163|ensembl:ENSP00000421361|refseq:NP_005246.2|refseq:NP_001305063.1|ensembl:ENSG00000178950(gene)|ensembl:ENST00000314167(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0030276"(clathrin binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031982"(vesicle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905224"(clathrin-coated pit assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR035892|interpro:IPR036869|rcsb pdb:4C57|rcsb pdb:4C58|rcsb pdb:4C59|rcsb pdb:4O38|rcsb pdb:4Y8D|rcsb pdb:5Y7Z|rcsb pdb:5Y80|reactome:R-HSA-432722|reactome:R-HSA-8856828|go:"GO:0072318"(clathrin coat disassembly)	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:+CTVzAL9y1B3+JIg6PHsj8QXIjE9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y2D5	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1754555|uniprotkb:Q9UG26|uniprotkb:B1ALX9|uniprotkb:B2RTU4|uniprotkb:B3KQ00|uniprotkb:B4DTZ2|uniprotkb:B7ZW07|uniprotkb:B9EJB5	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:akap2_human(display_long)|uniprotkb:AKAP2(gene name)|psi-mi:AKAP2(display_short)|uniprotkb:KIAA0920(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP-KL(gene name synonym)|uniprotkb:PRKA2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001004065.2|refseq:NP_001130034.1|refseq:NP_001185585.1|refseq:NP_009134.1|refseq:NP_671492.1|interpro:IPR029304	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xfHb6tD0ToXJPHpl4MlbKczjzSg9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P18085	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1237085|ensembl:ENSP00000306010|uniprotkb:P21371|uniprotkb:B2R7J7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:arf4_human(display_long)|uniprotkb:ARF4(gene name)|psi-mi:ARF4(display_short)|uniprotkb:ARF2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000168374(gene)|ensembl:ENST00000303436(transcript)|refseq:NP_001651.1|dip:DIP-38214N|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0060271"(cilium assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P18085|rcsb pdb:1Z6X|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AN3aBuSStAMrmkqq1HEDQtOiCy49606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P53680	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-297662|ensembl:ENSP00000263270|uniprotkb:O75977|uniprotkb:Q6PK67|uniprotkb:B2R4Z4	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ap2s1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit sigma(gene name synonym)|uniprotkb:AP2S1(gene name)|psi-mi:AP2S1(display_short)|uniprotkb:Sigma2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 17 kDa protein(gene name synonym)|uniprotkb:HA2 17 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP17(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP17(gene name synonym)|uniprotkb:AP17(gene name synonym)|uniprotkb:CLAPS2(gene name synonym)|uniprotkb:Clathrin assembly protein 2 sigma small chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit sigma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000042753(gene)|ensembl:ENST00000263270(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027156|rcsb pdb:6URI|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004060.2|refseq:NP_067586.1|refseq:NP_001288005.1|refseq:NP_001288007.1|refseq:NP_001288010.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AJxHeeoCpwPxjsRcAQkiAGaC9k09606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P63313	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2688673|uniprotkb:Q596K9|uniprotkb:P13472|ensembl:ENSP00000233143	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tyb10_human(display_long)|uniprotkb:PTMB10(gene name synonym)|uniprotkb:THYB10(gene name synonym)|uniprotkb:TMSB10(gene name)|psi-mi:TMSB10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_066926.1|ensembl:ENSG00000034510(gene)|ensembl:ENST00000233143(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042989"(sequestering of actin monomers)|interpro:IPR001152(Thymosin beta-4)|interpro:IPR038386	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:oyHgjBTa5Wd0RSnF3dTUPsgPV9w9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62258	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y5S2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1043430|uniprotkb:Q2L7A5|uniprotkb:Q86TJ1|uniprotkb:Q9ULU5|ensembl:ENSP00000355237|uniprotkb:A9JR72	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mrckb_human(display_long)|uniprotkb:CDC42-binding protein kinase beta(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase beta(gene name synonym)|uniprotkb:DMPK-like beta(gene name synonym)|uniprotkb:CDC42BPB(gene name)|psi-mi:CDC42BPB(display_short)|uniprotkb:KIAA1124(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000198752(gene)|ensembl:ENST00000361246(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR031597|interpro:IPR033232|interpro:IPR042718|rcsb pdb:3QFV|rcsb pdb:3TKU|rcsb pdb:4UAK|rcsb pdb:4UAL|rcsb pdb:5OTE|rcsb pdb:5OTF|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|refseq:NP_006026.3	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:FaheT9htZ/NtYfTKvNDcLqNtQiQ9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07737	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O94851	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2804835|uniprotkb:Q7Z3A8|uniprotkb:D3DQW5|uniprotkb:B4DGZ0|uniprotkb:B7Z849|uniprotkb:G3XAC8|uniprotkb:Q5KTR3|uniprotkb:Q5KTR4|ensembl:ENSP00000256194|ensembl:ENSP00000507067	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mica2_human(display_long)|uniprotkb:KIAA0750(gene name synonym)|uniprotkb:MICAL2(gene name)|psi-mi:MICAL2(display_short)|uniprotkb:MICAL2PV1(gene name synonym)|uniprotkb:MICAL2PV2(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001269592.1|refseq:NP_001269593.1|refseq:NP_001269594.1|refseq:NP_001269595.1|refseq:NP_001269596.1|refseq:NP_055447.1|refseq:NP_001333221.1|refseq:NP_001333222.1|refseq:NP_001333223.1|refseq:NP_001333224.1|refseq:NP_001333225.1|refseq:NP_001333226.1|refseq:NP_001333227.1|refseq:NP_001333228.1|refseq:XP_016874078.1|refseq:XP_016874079.1|refseq:XP_016874080.1|ensembl:ENSG00000133816(gene)|ensembl:ENST00000256194(transcript)|ensembl:ENST00000683283(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007507"(heart development)|go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0019417"(sulfur oxidation)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0043914"("NADPH:sulfur oxidoreductase activity")|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR029939|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2E9K	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:qbQ0zzaskf5owXjOkSPlufxobm89606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P46940	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P11171	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1050906|uniprotkb:P11176|uniprotkb:Q14245|uniprotkb:Q5TB35|uniprotkb:Q5VXN8|uniprotkb:Q8IXV9|uniprotkb:Q9Y578|uniprotkb:Q9Y579|uniprotkb:B1ALH8|uniprotkb:B1ALH9|uniprotkb:D3DPM9|uniprotkb:D3DPN0|ensembl:ENSP00000345259|ensembl:ENSP00000362904	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:epb41_human(display_long)|uniprotkb:Band 4.1(gene name synonym)|uniprotkb:EPB4.1(gene name synonym)|uniprotkb:4.1R(gene name synonym)|uniprotkb:EPB41(gene name)|psi-mi:EPB41(display_short)|uniprotkb:E41P(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001159477.1|refseq:NP_001159478.1|refseq:NP_004428.1|refseq:NP_976217.1|refseq:XP_016856078.1|refseq:XP_005245818.1|refseq:XP_005245821.1|ensembl:ENSG00000159023(gene)|ensembl:ENST00000343067(transcript)|ensembl:ENST00000373798(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045171"(intercellular bridge)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099738"(cell cortex region)|go:"GO:1904478"(regulation of intestinal absorption)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR021187|interpro:IPR029071|interpro:IPR035963|mint:P11171|rcsb pdb:1GG3|rcsb pdb:2RQ1|rcsb pdb:3QIJ|reactome:R-HSA-6794361|dip:DIP-17032N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ZCaM+kjScfGP23wRkFRwVyxOyvk9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P47756	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P63261	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P06753	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9NYL9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352614|ensembl:ENSP00000308753|uniprotkb:Q9NT43|uniprotkb:Q9NZR0|uniprotkb:B2R6G7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tmod3_human(display_long)|uniprotkb:TMOD3(gene name)|psi-mi:TMOD3(display_short)|uniprotkb:Ubiquitous tropomodulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000138594(gene)|ensembl:ENST00000308580(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|refseq:NP_055362.1|go:"GO:0048821"(erythrocyte development)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR004934(Tropomodulin)|interpro:IPR030133|interpro:IPR032675|mint:Q9NYL9|reactome:R-HSA-390522|reactome:R-HSA-9013418|reactome:R-HSA-9696264|refseq:XP_016877576.1|refseq:XP_016877577.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:crEfCAAepSPAE8ByBpD4Sr14P5I9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P28289	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2659631|uniprotkb:B2RB77|uniprotkb:Q5T7W3|uniprotkb:Q9BUF1|ensembl:ENSP00000259365|ensembl:ENSP00000378637|intact:EBI-10965302	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tmod1_human(display_long)|uniprotkb:Erythrocyte tropomodulin(gene name synonym)|uniprotkb:D9S57E(gene name synonym)|uniprotkb:TMOD(gene name synonym)|uniprotkb:TMOD1(gene name)|psi-mi:TMOD1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001159588.1|refseq:NP_003266.1|ensembl:ENST00000259365(transcript)|ensembl:ENST00000395211(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0070307"(lens fiber cell development)|interpro:IPR004934(Tropomodulin)|interpro:IPR030135|interpro:IPR032675|mint:P28289|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4Z8G|rcsb pdb:4Z94|reactome:R-HSA-390522|ensembl:ENSG00000136842(gene)	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xbmnoh2E0cuP4ZYmnhlOo8QDnHw9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P35749	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1052928|uniprotkb:O00396|uniprotkb:O94944|uniprotkb:P78422|uniprotkb:Q3MNF0|uniprotkb:Q3MNF1|uniprotkb:Q3MIV8|uniprotkb:D2JYH7|ensembl:ENSP00000300036|ensembl:ENSP00000488461	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:myh11_human(display_long)|uniprotkb:Myosin heavy chain 11(gene name synonym)|uniprotkb:Myosin heavy chain, smooth muscle isoform(gene name synonym)|uniprotkb:SMMHC(gene name synonym)|uniprotkb:MYH11(gene name)|psi-mi:MYH11(display_short)|uniprotkb:KIAA0866(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	dip:DIP-47268N|refseq:NP_002465.1|refseq:NP_001035202.1|refseq:NP_001035203.1|refseq:NP_074035.1|ensembl:ENSG00000133392(gene)|ensembl:ENSG00000276480(gene)|ensembl:ENST00000300036(transcript)|ensembl:ENST00000634050(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0032982"(myosin filament)|go:"GO:0042470"(melanosome)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35749|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016878739.1	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:iE4qZJHXiIfxtk9An/7T4DKbwIU9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O60333	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q12756	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O43896	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1644048|uniprotkb:O75186|uniprotkb:Q5U618|uniprotkb:D3DTL6|ensembl:ENSP00000320821	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:kif1c_human(display_long)|uniprotkb:KIF1C(gene name)|psi-mi:KIF1C(display_short)|uniprotkb:KIAA0706(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099463|imex:IM-25792-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006603.2|refseq:XP_005256481.1|dip:DIP-40376N|ensembl:ENSG00000129250(gene)|ensembl:ENST00000320785(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|mint:O43896|rcsb pdb:2G1L|reactome:R-HSA-6811434|reactome:R-HSA-983189	-	-	-	figure legend:Supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2018/04/06	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AeG87fdDj70xFfsQCPuXA9iiubo9606	rigid:Q/BfKCvnrbib2MZx+4+G76kjJKU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q6ZNL6	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-7962481|ensembl:ENSP00000285046|uniprotkb:Q6MZY1|uniprotkb:Q8N8G4|uniprotkb:Q7Z303|uniprotkb:B3KVQ3|uniprotkb:Q8N861|intact:UNK-5489544|uniprotkb:Q8IYP3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fgd5_human(display_long)|uniprotkb:Zinc finger FYVE domain-containing protein 23(gene name synonym)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000154783(gene)|ensembl:ENST00000285046(transcript)|go:"GO:0001726"(ruffle)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|mint:Q6ZNL6|rcsb pdb:3MPX|reactome:R-HSA-9013149|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005829"(cytosol)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|refseq:NP_689749.3	-	-	comment:mint|comment:homomint|function:May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q8IVF7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-7242231|intact:MINT-1182764|uniprotkb:Q6ZRJ1|uniprotkb:B0JZA7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fmnl3_human(display_long)|uniprotkb:FHOD3(gene name synonym)|uniprotkb:KIAA2014(gene name synonym)|uniprotkb:FMNL3(gene name)|psi-mi:FMNL3(display_short)|uniprotkb:WBP3(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 3(gene name synonym)|uniprotkb:WW domain-binding protein 3(gene name synonym)|uniprotkb:FRL2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	reactome:R-HSA-5663220|interpro:IPR043592|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010473(Diaphanous GTPase-binding)|refseq:NP_783863.4|refseq:NP_944489.2|interpro:IPR015425(Actin-binding FH2)|refseq:XP_005269275.1|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051015"(actin filament binding)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR011989(Armadillo-like helical)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013409|interpro:IPR027655|interpro:IPR042201	-	-	comment:mint|comment:homomint	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:sm2tPWzh9H/+mwiMT73nHTzGx0E9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O15371	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q14694	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2510389|uniprotkb:B4DS84|uniprotkb:B2RDJ8|uniprotkb:Q9BWG7|uniprotkb:Q9NSL7|ensembl:ENSP00000219473	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ubp10_human(display_long)|uniprotkb:USP10(gene name)|psi-mi:USP10(display_short)|uniprotkb:KIAA0190(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005144.2|ensembl:ENSP00000219473|ensembl:ENST00000570191|ensembl:ENSP00000457411|refseq:NP_001259004.1|ensembl:ENSG00000103194(gene)|ensembl:ENST00000219473(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR018200|interpro:IPR028767|interpro:IPR028889|interpro:IPR038765|mint:Q14694|reactome:R-HSA-5656169|reactome:R-HSA-5689880|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:W34ZdOIilLOVI8SXqCH3rOmmloo9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P51571	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UNL2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1043938|uniprotkb:Q549M4|ensembl:ENSP00000265044|uniprotkb:B2R7D0|uniprotkb:D3DNK5|uniprotkb:B4E2P2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ssrg_human(display_long)|uniprotkb:Signal sequence receptor subunit gamma(gene name synonym)|uniprotkb:SSR3(gene name)|psi-mi:SSR3(display_short)|uniprotkb:TRAPG(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_009038.1|ensembl:ENSG00000114850(gene)|ensembl:ENST00000265044(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009779(Translocon-associated, gamma subunit)|mint:Q9UNL2|reactome:R-HSA-1799339|refseq:NP_001295126.1|refseq:NP_001295133.1|refseq:NP_001295134.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Fb918T41oaTpc+kzNIygp1h1tlo9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q01105	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P06454	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P55036	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-359318|uniprotkb:Q5VWC5|uniprotkb:Q9NS92|uniprotkb:D3DV16|ensembl:ENSP00000357879	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:psmd4_human(display_long)|uniprotkb:PSMD4(gene name)|psi-mi:PSMD4(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Antisecretory factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002801.1|dip:DIP-38189N|ensembl:ENSG00000159352(gene)|ensembl:ENST00000368884(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|mint:P55036|rcsb pdb:1P9C|rcsb pdb:1P9D|rcsb pdb:1UEL|rcsb pdb:1YX4|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:2KDE|rcsb pdb:2KDF|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6MUN|rcsb pdb:6U19|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:FTJG3ns3Ag/Y3xP3yEydGxppRcA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O00231	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:BgQKXK7gMMihacRCI+g/pBnRN309606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y520	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_055987.2|refseq:XP_006711301.1|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034063"(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|ensembl:ENST00000338920|ensembl:ENSP00000343629|ensembl:ENSG00000117523|ensembl:ENST00000426496|ensembl:ENSP00000410219|ensembl:ENST00000647382|ensembl:ENSP00000495867|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9NQ29	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-473747|uniprotkb:Q96S32|uniprotkb:Q9NPH4|uniprotkb:B8ZZ13|ensembl:ENSP00000293872	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:luc7l_human(display_long)|uniprotkb:SR+89(gene name synonym)|uniprotkb:Putative SR protein LUC7B1(gene name synonym)|uniprotkb:LUC7L(gene name)|psi-mi:LUC7L(display_short)|uniprotkb:LUC7L1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001307155.1|refseq:NP_001317349.1|refseq:NP_060502.1|refseq:NP_958815.1|ensembl:ENSG00000007392(gene)|ensembl:ENST00000293872(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0042802"(identical protein binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9NQ29	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Hsl0VZTCTP6UrKlo/FHOVwZqCaw9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y608	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001127841.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:NP_001269620.1|ensembl:ENSG00000093167(gene)|ensembl:ENST00000336686(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030275"(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:XP_016862973.1|refseq:NP_001335239.1|refseq:NP_001335240.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96AG4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49257	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005561.1|ensembl:ENSG00000074695(gene)|ensembl:ENST00000251047(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033085|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-948021|reactome:R-HSA-9013423|dip:DIP-42188N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q92743	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352256|uniprotkb:Q9UNS5|uniprotkb:D3DRE4|ensembl:ENSP00000357980	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:htra1_human(display_long)|uniprotkb:HTRA1(gene name)|psi-mi:HTRA1(display_short)|uniprotkb:HTRA(gene name synonym)|uniprotkb:PRSS11(gene name synonym)|uniprotkb:High-temperature requirement A serine peptidase 1(gene name synonym)|uniprotkb:L56(gene name synonym)|uniprotkb:Serine protease 11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002766.1|ensembl:ENSG00000166033(gene)|ensembl:ENST00000368984(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097187"(dentinogenesis)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR036034|interpro:IPR036058|interpro:IPR041489|rcsb pdb:2JOA|rcsb pdb:2YTW|rcsb pdb:3NUM|rcsb pdb:3NWU|rcsb pdb:3NZI|rcsb pdb:3TJN|rcsb pdb:3TJO|rcsb pdb:3TJQ|rcsb pdb:6Z0E|rcsb pdb:6Z0X|rcsb pdb:6Z0Y|reactome:R-HSA-1474228|dip:DIP-33195N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Y7lT7nyI9N/3imHOz8Ng+Zagf509606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P09429	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P68871	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-715554|ensembl:ENSP00000333994|ensembl:ENSP00000494175|uniprotkb:P02023|uniprotkb:Q13852|uniprotkb:Q14481|uniprotkb:Q14510|uniprotkb:Q45KT0|uniprotkb:Q6FI08|uniprotkb:Q8IZI1|uniprotkb:Q9BX96|uniprotkb:Q9UCP8|uniprotkb:Q9UCP9|uniprotkb:A4GX73|uniprotkb:B2ZUE0|uniprotkb:Q549N7|uniprotkb:Q6R7N2|uniprotkb:Q9UCD6	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:hbb_human(display_long)|uniprotkb:Hemoglobin beta chain(gene name synonym)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000244734(gene)|ensembl:ENST00000335295(transcript)|ensembl:ENST00000647020(transcript)|refseq:NP_000509.1|rcsb pdb:1XZ4|rcsb pdb:1XZ2|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YZI|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:1YVT|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3HXN|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P68871|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|go:"GO:0072562"(blood microparticle)|rcsb pdb:1A3O|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CBL|rcsb pdb:1CBM|rcsb pdb:1CH4|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1J3Z|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-6798695|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-983231|rcsb pdb:7JY3|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:3W4U|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6FQF|rcsb pdb:6HAL|rcsb pdb:4ROM|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|dip:DIP-35526N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Y5tl4dXE3PBfaK/0lROD6QJ4U+c9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P02042	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-6152722|uniprotkb:Q8WXT7|uniprotkb:Q3Y5H3|ensembl:ENSP00000494708|ensembl:ENSP00000497529	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:hbd_human(display_long)|uniprotkb:Delta-globin(gene name synonym)|uniprotkb:Hemoglobin delta chain(gene name synonym)|uniprotkb:HBD(gene name)|psi-mi:HBD(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000510.1|ensembl:ENSG00000223609(gene)|ensembl:ENST00000643122(transcript)|ensembl:ENST00000650601(transcript)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1SHR|rcsb pdb:1SI4|reactome:R-HSA-983231	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8xPXyB/GW9LbJrqYzjTXaBgRryY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q6Y7W6	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O00622	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1237454|uniprotkb:O14934|uniprotkb:O43775|uniprotkb:Q9BZL7|ensembl:ENSP00000398736	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ccn1_human(display_long)|uniprotkb:CCN1(gene name)|psi-mi:CCN1(display_short)|uniprotkb:CYR61(gene name synonym)|uniprotkb:Cellular communication network factor 1(gene name synonym)|uniprotkb:Cysteine-rich angiogenic inducer 61(gene name synonym)|uniprotkb:GIG1(gene name synonym)|uniprotkb:IGFBP10(gene name synonym)|uniprotkb:Insulin-like growth factor-binding protein 10(gene name synonym)|uniprotkb:Protein CYR61(gene name synonym)|uniprotkb:Protein GIG1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001545.2|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000304"(positive regulation of ceramide biosynthetic process)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR006208(Cystine knot)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012395(IGFBP-related, CNN)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|mint:O00622|rcsb pdb:4D0Z|rcsb pdb:4D11|reactome:R-HSA-381426|reactome:R-HSA-8957275|go:"GO:0030198"(extracellular matrix organization)|ensembl:ENSG00000142871(gene)|ensembl:ENST00000451137(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002041"(intussusceptive angiogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003278"(apoptotic process involved in heart morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005178"(integrin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:zjqBcViT2Kyh+41SJeOu/rcJqSk9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y678	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O00299	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000404037|ensembl:ENSP00000404589|ensembl:ENSP00000406088|ensembl:ENSP00000406335|ensembl:ENSP00000406968|ensembl:ENSP00000407429|ensembl:ENSP00000407791|ensembl:ENSP00000408094|ensembl:ENSP00000408357|ensembl:ENSP00000409247|ensembl:ENSP00000409979|ensembl:ENSP00000410965|ensembl:ENSP00000412217|ensembl:ENSP00000413330|ensembl:ENSP00000416211|ensembl:ENSP00000477623|ensembl:ENSP00000478930|ensembl:ENSP00000479501|ensembl:ENSP00000479808|ensembl:ENSP00000480256|ensembl:ENSP00000482255|ensembl:ENSP00000484581|ensembl:ENSP00000364934|ensembl:ENSP00000364935|ensembl:ENSP00000364940|ensembl:ENSP00000372896|ensembl:ENSP00000372897|ensembl:ENSP00000379229|ensembl:ENSP00000382926|ensembl:ENSP00000382931|ensembl:ENSP00000391395|ensembl:ENSP00000398056|ensembl:ENSP00000400280|ensembl:ENSP00000400532|ensembl:ENSP00000401292	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|ensembl:ENST00000375779(transcript)|ensembl:ENST00000375780(transcript)|ensembl:ENST00000375784(transcript)|ensembl:ENST00000383404(transcript)|ensembl:ENST00000383405(transcript)|ensembl:ENST00000395892(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072562"(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|go:"GO:0005634"(nucleus)|ensembl:ENSG00000206394(gene)|ensembl:ENSG00000213719(gene)|ensembl:ENSG00000223639(gene)|ensembl:ENSG00000226248(gene)|ensembl:ENSG00000226417(gene)|ensembl:ENSG00000226651(gene)|ensembl:ENSG00000230685(gene)|ensembl:ENST00000400052(transcript)|ensembl:ENST00000400058(transcript)|ensembl:ENST00000415179(transcript)|ensembl:ENST00000418285(transcript)|ensembl:ENST00000420458(transcript)|ensembl:ENST00000422167(transcript)|ensembl:ENST00000423055(transcript)|ensembl:ENST00000423143(transcript)|ensembl:ENST00000423804(transcript)|ensembl:ENST00000425464(transcript)|ensembl:ENST00000431921(transcript)|ensembl:ENST00000433916(transcript)|ensembl:ENST00000434202(transcript)|ensembl:ENST00000435242(transcript)|ensembl:ENST00000438708(transcript)|ensembl:ENST00000438750(transcript)|ensembl:ENST00000442045(transcript)|ensembl:ENST00000447338(transcript)|ensembl:ENST00000447369(transcript)|ensembl:ENST00000451546(transcript)|ensembl:ENST00000456863(transcript)|ensembl:ENST00000457485(transcript)|ensembl:ENST00000614673(transcript)|ensembl:ENST00000614982(transcript)|ensembl:ENST00000616760(transcript)|ensembl:ENST00000618288(transcript)|ensembl:ENST00000619727(transcript)|ensembl:ENST00000621055(transcript)|ensembl:ENST00000622613(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036282|interpro:IPR040079|mint:O00299|interpro:IPR036249|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96CT7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-5461329|ensembl:ENSP00000408730|ensembl:ENSP00000471455	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:cc124_human(display_long)|uniprotkb:CCDC124(gene name)|psi-mi:CCDC124(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001129675.1|refseq:NP_612451.1|ensembl:ENSG00000007080(gene)|ensembl:ENST00000445755(transcript)|ensembl:ENST00000597436(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0030496"(midbody)|go:"GO:0051301"(cell division)|interpro:IPR010422(Protein of unknown function DUF1014)|mint:Q96CT7|rcsb pdb:6Z6L|rcsb pdb:6ZM7|rcsb pdb:6ZME	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:w3LqsScVHWABZgIwYZXS6Ly9CiM9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O43852	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P27797	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P54289	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-9690154|uniprotkb:Q17R45|uniprotkb:Q9UD80|uniprotkb:Q9UD81|uniprotkb:Q9UD82|ensembl:ENSP00000348589	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ca2d1_human(display_long)|uniprotkb:CACNA2D1(gene name)|psi-mi:CACNA2D1(display_short)|uniprotkb:CACNL2A(gene name synonym)|uniprotkb:CCHL2A(gene name synonym)|uniprotkb:MHS3(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha-2/delta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000713.2|refseq:XP_005250627.1|refseq:XP_005250629.1|refseq:XP_005250630.1|refseq:XP_005250631.1|ensembl:ENSG00000153956(gene)|ensembl:ENST00000356253(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013608(VWA N-terminal)|interpro:IPR013680(Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region)|interpro:IPR036465	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:+IdPU9/mRR3gZjLuAHH7gXtgRlw9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P35613	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P36543	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-348639|ensembl:ENSP00000253413|uniprotkb:A8MUE4|uniprotkb:A8MUN4	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:vate1_human(display_long)|uniprotkb:ATP6V1E1(gene name)|psi-mi:ATP6V1E1(display_short)|uniprotkb:ATP6E(gene name synonym)|uniprotkb:Vacuolar proton pump subunit E 1(gene name synonym)|uniprotkb:V-ATPase 31 kDa subunit(gene name synonym)|uniprotkb:ATP6E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001687.1|ensembl:ENSG00000131100(gene)|ensembl:ENST00000253413(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|interpro:IPR038495|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:NP_001034455.1|refseq:NP_001034456.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:tTf7Cl6DOsN3USZrmZijWhmhEhg9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61421	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-954063|ensembl:ENSP00000290949|uniprotkb:P12953|uniprotkb:Q02547	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000159720(gene)|ensembl:ENST00000290949(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|go:"GO:0016324"(apical plasma membrane)|refseq:NP_004682.2|dip:DIP-47435N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9P291	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2843626|uniprotkb:Q53HK2|uniprotkb:Q9H2Q0|ensembl:ENSP00000361917	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:armx1_human(display_long)|uniprotkb:ARMCX1(gene name)|psi-mi:ARMCX1(display_short)|uniprotkb:ALEX1(gene name synonym)|uniprotkb:ARM protein lost in epithelial cancers on chromosome X 1(gene name synonym)|uniprotkb:AD032(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_057692.1|interpro:IPR000225(Armadillo)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR016024(Armadillo-type fold)|ensembl:ENSG00000126947(gene)|ensembl:ENST00000372829(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061484"(hematopoietic stem cell homeostasis)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ucAvi3iB/4oEzG3nk0rNYswJZ189606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P04083	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P02768	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UG63	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2959697|ensembl:ENSP00000287844|uniprotkb:Q96TE8|uniprotkb:O60864|uniprotkb:Q75MJ0|uniprotkb:Q75MJ1	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:abcf2_human(display_long)|uniprotkb:ABCF2(gene name)|psi-mi:ABCF2(display_short)|uniprotkb:Iron-inhibited ABC transporter 2(gene name synonym)|uniprotkb:HUSSY-18(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000033050(gene)|ensembl:ENST00000287844(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|mint:Q9UG63|go:"GO:0016020"(membrane)|refseq:NP_005683.2|refseq:NP_009120.1|refseq:XP_016867128.1|refseq:XP_016867129.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TdGWfZ4OYohgxKLL1uyz7X+FWmQ9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q8NBS9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:bz5VVWMPFLTRKwph60UFASjsFN49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P29401	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|ensembl:ENSP00000405455|ensembl:ENSP00000417773|intact:EBI-11110174	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|ensembl:ENSG00000163931(gene)|ensembl:ENST00000423525(transcript)|ensembl:ENST00000462138(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031982"(vesicle)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|reactome:R-HSA-163754|reactome:R-HSA-71336|refseq:XP_011532356.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q02978	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9H299	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-5234893|uniprotkb:Q5T122|ensembl:ENSP00000270792	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sh3l3_human(display_long)|uniprotkb:SH3BGRL3(gene name)|psi-mi:SH3BGRL3(display_short)|uniprotkb:SH3 domain-binding protein 1(gene name synonym)|uniprotkb:P1725(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112576.1|ensembl:ENSG00000142669(gene)|ensembl:ENST00000270792(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016604"(nuclear body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006993(SH3-binding, glutamic acid-rich protein)|interpro:IPR036249|rcsb pdb:1SJ6	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:mD13ce5qQqvgJtLXWU+/Ssd4Rks9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P30041	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2255129|uniprotkb:A8JZY7|uniprotkb:P32077|uniprotkb:Q5TAH4|uniprotkb:Q5ZEZ8|ensembl:ENSP00000342026	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prdx6_human(display_long)|uniprotkb:PRDX6(gene name)|psi-mi:PRDX6(display_short)|uniprotkb:AOP2(gene name synonym)|uniprotkb:KIAA0106(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:24 kDa protein(gene name synonym)|uniprotkb:Liver 2D page spot 40(gene name synonym)|uniprotkb:Red blood cells page spot 12(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004896.1|ensembl:ENSG00000117592(gene)|ensembl:ENST00000340385(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:1PRX|rcsb pdb:5B6M|rcsb pdb:5B6N|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0042744"(hydrogen peroxide catabolic process)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ZMsHgrAJf0VJiCELzo+zSi8Ji+49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P32119	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O60568	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-741582|uniprotkb:Q540C3|ensembl:ENSP00000223127|uniprotkb:B2R6W6	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:plod3_human(display_long)|uniprotkb:PLOD3(gene name)|psi-mi:PLOD3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000106397(gene)|ensembl:ENST00000223127(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005506"(iron ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008104"(protein localization)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0021915"(neural tube development)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033823"(procollagen glucosyltransferase activity)|go:"GO:0042311"(vasodilation)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O60568|rcsb pdb:6FXK|rcsb pdb:6FXM|rcsb pdb:6FXR|rcsb pdb:6FXT|rcsb pdb:6FXX|rcsb pdb:6FXY|rcsb pdb:6TE3|rcsb pdb:6TEC|refseq:NP_001075.1|rcsb pdb:6TES|rcsb pdb:6TEU|rcsb pdb:6TEX|rcsb pdb:6TEZ|reactome:R-HSA-1650814|rcsb pdb:6WFV	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:dvfk+ko7squrB6c4AayW+fR8EnE9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P00558	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P52209	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-372761|uniprotkb:Q9BWD8|intact:EBI-11020895|uniprotkb:A8K2Y9|ensembl:ENSP00000270776|uniprotkb:B4DQJ8	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:6pgd_human(display_long)|uniprotkb:PGD(gene name)|psi-mi:PGD(display_short)|uniprotkb:PGDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001291380.1|refseq:NP_001291381.1|refseq:NP_002622.2|ensembl:ENSG00000142657(gene)|ensembl:ENST00000270776(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|mint:P52209|rcsb pdb:2JKV|rcsb pdb:4GWG|rcsb pdb:4GWK|rcsb pdb:5UQ9|reactome:R-HSA-71336|interpro:IPR036291	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:SgbOgCLmdWm3QnN6fQfkHG6iunw9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q15084	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07237	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O15460	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-348033|ensembl:ENSP00000166534|ensembl:ENSP00000368398|ensembl:ENSP00000384999|uniprotkb:Q8WWN0|uniprotkb:D3DQ85|uniprotkb:D3DQ86	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:p4ha2_human(display_long)|uniprotkb:UNQ290/PRO330(orf name)|uniprotkb:P4HA2(gene name)|psi-mi:P4HA2(display_short)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENST00000166534(transcript)|ensembl:ENST00000379104(transcript)|ensembl:ENST00000401867(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0009055"(electron transfer activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|interpro:IPR019734|mint:O15460|rcsb pdb:6EVL|rcsb pdb:6EVM|rcsb pdb:6EVN|rcsb pdb:6EVO|rcsb pdb:6EVP|reactome:R-HSA-1650814|ensembl:ENSG00000072682(gene)|refseq:NP_001136071.1|refseq:NP_004190.1|refseq:NP_001017973.1|refseq:NP_001017974.1|refseq:NP_001136070.1|refseq:XP_016865500.1|refseq:XP_005272173.1|refseq:XP_005272174.1|refseq:XP_005272175.1|refseq:XP_005272176.1|refseq:XP_005272177.1|refseq:XP_006714791.1|refseq:XP_006714792.1|refseq:XP_006714793.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:VppOE5KSA6wKWCFN4mCUJsFHDIA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P00338	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P48735	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49448	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-720168|uniprotkb:Q9UDQ4|uniprotkb:B2R8G0|ensembl:ENSP00000327589|ensembl:ENSP00000500546	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dhe4_human(display_long)|uniprotkb:GLUD2(gene name)|psi-mi:GLUD2(display_short)|uniprotkb:GLUDP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_036216.2|ensembl:ENSG00000182890(gene)|ensembl:ENSG00000288118(gene)|ensembl:ENST00000328078(transcript)|ensembl:ENST00000673493(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0043531"(ADP binding)|go:"GO:0070728"(leucine binding)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|rcsb pdb:6G2U|reactome:R-HSA-2151201|reactome:R-HSA-8964539	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:F6sq5B69eoiIC2y3eOtEy029WQQ9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P00367	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865|uniprotkb:B3KV55|uniprotkb:B4DGN5	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000148672(gene)|ensembl:ENST00000277865(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042802"(identical protein binding)|refseq:NP_005262.1|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|reactome:R-HSA-2151201|reactome:R-HSA-8964539	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P04406	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O60762	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:znbNDwp7t238ByanlbQzsTMvwTY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q16698	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2554876|uniprotkb:B7Z6B8|uniprotkb:Q93085|uniprotkb:Q2M304|ensembl:ENSP00000220764|intact:EBI-10969978	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:decr_human(display_long)|uniprotkb:DECR(gene name synonym)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)|uniprotkb:DECR1(gene name)|psi-mi:DECR1(display_short)|uniprotkb:SDR18C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 18C member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001350.1|ensembl:ENSG00000104325(gene)|ensembl:ENST00000220764(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|mint:Q16698|rcsb pdb:1W6U|rcsb pdb:1W73|rcsb pdb:1W8D|reactome:R-HSA-77288|interpro:IPR036291|refseq:NP_001317504.1|refseq:XP_016868636.1|refseq:XP_016868637.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:l/8jxdd4pqUIUV2eIThvXTd66yE9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P04075	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y305	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2548214|ensembl:ENSP00000336580|uniprotkb:B3KNC9|uniprotkb:B7ZM94	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:acot9_human(display_long)|uniprotkb:ACOT9(gene name)|psi-mi:ACOT9(display_short)|uniprotkb:Acyl-CoA thioester hydrolase 9(gene name synonym)|uniprotkb:CGI-16(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000123130(gene)|ensembl:ENST00000336430(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR029069|interpro:IPR033120|mint:Q9Y305|reactome:R-HSA-77289|refseq:NP_001028755.2|refseq:NP_001032248.1|refseq:NP_001317188.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:WbPOPMGV/9XQRxLufTKCXvYQH/Y9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P05387	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P46777	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62891	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q59GN2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-10101575	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:r39l5_human(display_long)|uniprotkb:RPL39P5(gene name)|psi-mi:RPL39P5(display_short)|uniprotkb:60S ribosomal protein L39 pseudogene 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR023626|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:vqUrMKZ0TgDiCZbYR2+EBEZS8QY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61353	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q6ZNG9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-13309813|ensembl:ENSP00000494883|uniprotkb:Q8IYY0	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:krba2_human(display_long)|uniprotkb:KRBA2(gene name)|psi-mi:KRBA2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000184619(gene)|ensembl:ENST00000643221(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0015074"(DNA integration)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036051|interpro:IPR036397|refseq:NP_001291876.1|refseq:NP_998762.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:pfVTsBaFoCQbwChKch6i+EBzggA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61254	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352405|uniprotkb:Q02877|uniprotkb:Q6IPY2|uniprotkb:B2R4F0|uniprotkb:D3DTR8|ensembl:ENSP00000462322|ensembl:ENSP00000463470|ensembl:ENSP00000463784|ensembl:ENSP00000498177	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl26_human(display_long)|uniprotkb:RPL26(gene name)|psi-mi:RPL26(display_short)|uniprotkb:Large ribosomal subunit protein uL24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000978.1|refseq:NP_001302459.1|refseq:NP_001302460.1|ensembl:ENST00000582556(transcript)|ensembl:ENST00000583011(transcript)|ensembl:ENST00000584164(transcript)|ensembl:ENST00000648839(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|ensembl:ENSG00000161970(gene)|go:"GO:0022626"(cytosolic ribosome)|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904803"(regulation of translation involved in cellular response to UV)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:P61254|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|go:"GO:0034644"(cellular response to UV)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:5LKS|reactome:R-HSA-156827|dip:DIP-33198N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:VAROWOFmYvolVgc/e5E1jAmNuaY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q02543	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-350523|ensembl:ENSP00000222247	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl18a_human(display_long)|uniprotkb:RPL18A(gene name)|psi-mi:RPL18A(display_short)|uniprotkb:Large ribosomal subunit protein eL20(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000971.1|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:Q02543|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|go:"GO:0097327"(response to antineoplastic agent)|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|ensembl:ENSG00000105640(gene)|ensembl:ENST00000222247(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6ZME|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:O9XdW7Let2GcJpJLVuUtatVVv1I9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62906	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P78344	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q04637	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O15372	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-709735|ensembl:ENSP00000429931	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O00303	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9H2U1	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1047643|uniprotkb:Q70JU3|uniprotkb:Q8IYE5|uniprotkb:Q9P240|uniprotkb:B2RB00|ensembl:ENSP00000417078	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dhx36_human(display_long)|uniprotkb:DEAD/H box polypeptide 36(gene name synonym)|uniprotkb:DEAH-box protein 36(gene name synonym)|uniprotkb:G4-resolvase-1(gene name synonym)|uniprotkb:RNA helicase associated with AU-rich element protein(gene name synonym)|uniprotkb:MLE-like protein 1(gene name synonym)|uniprotkb:DHX36(gene name)|psi-mi:DHX36(display_short)|uniprotkb:DDX36(gene name synonym)|uniprotkb:KIAA1488(gene name synonym)|uniprotkb:MLEL1(gene name synonym)|uniprotkb:RHAU(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001107869.1|refseq:NP_065916.2|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0005829"(cytosol)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070883"(pre-miRNA binding)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902064"(regulation of transcription from RNA polymerase II promoter involved in spermatogenesis)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR027417|ensembl:ENSG00000174953(gene)|ensembl:ENST00000496811(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001503"(ossification)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rcsb pdb:2N16|rcsb pdb:2N21|rcsb pdb:6Q6R|reactome:R-HSA-3134963|mint:Q9H2U1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CvYmO1OB0zu5ZCYzQmKvCYGc3+k9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q15650	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2800143|uniprotkb:Q96ED7|uniprotkb:Q9UKH0|uniprotkb:B2RAS0|ensembl:ENSP00000261884	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:trip4_human(display_long)|uniprotkb:Thyroid receptor-interacting protein 4(gene name synonym)|uniprotkb:TRIP4(gene name)|psi-mi:TRIP4(display_short)|uniprotkb:RQT4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_057297.2|refseq:NP_001308853.1|ensembl:ENSG00000103671(gene)|ensembl:ENST00000261884(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:1901998"(toxin transport)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR015947(PUA-like)|interpro:IPR039128|rcsb pdb:2E5O|go:"GO:0005815"(microtubule organizing center)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:fecS9E0obnl+xsx/r9OrmToZEbs9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O14773	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9NZI7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2795133|uniprotkb:Q68CT0|uniprotkb:Q86Y57|uniprotkb:Q9H8V0|uniprotkb:Q9UD76|uniprotkb:Q9UD78|ensembl:ENSP00000283628|ensembl:ENSP00000283629	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ubip1_human(display_long)|uniprotkb:UBP1(gene name)|psi-mi:UBP1(display_short)|uniprotkb:LBP1(gene name synonym)|uniprotkb:Transcription factor LBP-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001121632.1|refseq:NP_001121633.1|refseq:NP_055332.3|ensembl:ENSG00000153560(gene)|ensembl:ENST00000283628(transcript)|ensembl:ENST00000283629(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037600|interpro:IPR041418|mint:Q9NZI7|go:"GO:0032897"(negative regulation of viral transcription)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:aMcHSKF2w0CPIYmoyowV2a3I9Tk9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q12800	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q00059	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q15369	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q7KZF4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q14498	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051(gene)|ensembl:ENST00000253363(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|dip:DIP-32928N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96AQ6	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q8WU90	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1042636|uniprotkb:Q5QTQ4|uniprotkb:Q8WZ06|uniprotkb:Q9NUZ3|uniprotkb:Q9P079|uniprotkb:Q9NZ37|uniprotkb:B4DMW2|uniprotkb:D3DPG7|ensembl:ENSP00000338788	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:zc3hf_human(display_long)|uniprotkb:ZC3H15(gene name)|psi-mi:ZC3H15(display_short)|uniprotkb:DFRP1(gene name synonym)|uniprotkb:LEREPO4(gene name synonym)|uniprotkb:DRG family-regulatory protein 1(gene name synonym)|uniprotkb:Likely ortholog of mouse immediate early response erythropoietin 4(gene name synonym)|uniprotkb:HSPC303(orf name)|uniprotkb:HT010(orf name)|uniprotkb:MSTP012(orf name)|uniprotkb:PP730(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_060941.2|ensembl:ENSG00000065548(gene)|ensembl:ENST00000337859(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR032378|interpro:IPR036855|interpro:IPR041367|mint:Q8WU90	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:MrcssHMHDoQKqsIXdhfMWOnHlBY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61011	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2854176|uniprotkb:B2R759|uniprotkb:P13624|uniprotkb:B4DUW6|ensembl:ENSP00000216774|ensembl:ENSP00000451818|ensembl:ENSP00000504518|ensembl:ENSP00000504673	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:srp54_human(display_long)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:XP_011535408.1|refseq:NP_001139754.1|refseq:NP_003127.1|ensembl:ENSG00000100883(gene)|ensembl:ENST00000678963(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019003"(GDP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|mint:P61011|rcsb pdb:1MFQ|rcsb pdb:1QB2|rcsb pdb:5L3Q|rcsb pdb:6Y2Z|rcsb pdb:6Y30|rcsb pdb:6Y31|rcsb pdb:6Y32|rcsb pdb:7NFX|ensembl:ENST00000216774(transcript)|reactome:R-HSA-1799339|ensembl:ENST00000556994(transcript)|ensembl:ENST00000677647(transcript)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8iRlU+NvhLEJNv7B90TAZyRqwiY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49591	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1053431|uniprotkb:Q5T5C8|uniprotkb:Q9NSE3|uniprotkb:B2R6Y9|ensembl:ENSP00000234677	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sysc_human(display_long)|uniprotkb:SARS1(gene name)|psi-mi:SARS1(display_short)|uniprotkb:SARS(gene name synonym)|uniprotkb:SERS(gene name synonym)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006504.2|ensembl:ENSG00000031698(gene)|ensembl:ENST00000234677(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019899"(enzyme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR033729|interpro:IPR042103|rcsb pdb:3VBB|rcsb pdb:4L87|rcsb pdb:4RQE|rcsb pdb:4RQF|reactome:R-HSA-2408557|reactome:R-HSA-379716|dip:DIP-38215N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:4+Ai/MIybmiKJyfa0C0bhnW/CG49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96PU8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9H361	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1055272|uniprotkb:Q8NHV0|uniprotkb:Q9H086|ensembl:ENSP00000281589	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pabp3_human(display_long)|uniprotkb:"Testis-specific poly(A)-binding protein"(gene name synonym)|uniprotkb:PABPC3(gene name)|psi-mi:PABPC3(display_short)|uniprotkb:PABP3(gene name synonym)|uniprotkb:PABPL3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112241.2|ensembl:ENSG00000151846(gene)|ensembl:ENST00000281589(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q9H361|rcsb pdb:2D9P|rcsb pdb:4IVE	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:g/tDJDBcBC+s8P6LGDIwgZO8HHY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P11940	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9HCE1	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q12849	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1054150|uniprotkb:Q6ZST3|uniprotkb:Q8NBD2|uniprotkb:Q4W5S5|uniprotkb:Q8IWD6|uniprotkb:B3KPW0|intact:EBI-28981368|ensembl:ENSP00000254799	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:grsf1_human(display_long)|uniprotkb:GRSF1(gene name)|psi-mi:GRSF1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002083.3|refseq:XP_011530199.1|ensembl:ENSP00000254799|ensembl:ENST00000502323|ensembl:ENSP00000425430|refseq:NP_001091947.1|ensembl:ENSG00000132463(gene)|ensembl:ENST00000254799(transcript)|go:"GO:0000962"(positive regulation of mitochondrial RNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033106|interpro:IPR034424|interpro:IPR034425|interpro:IPR034426|interpro:IPR035979|rcsb pdb:2LMI|rcsb pdb:4QU6|rcsb pdb:4QU7|reactome:R-HSA-192823	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:89Xul87okYruMW1PQtPMbBTqX+09606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P51116	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9NSD9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-353803|uniprotkb:B4DFM0|uniprotkb:O95708|uniprotkb:Q9NZZ6|uniprotkb:Q4ZFX1|uniprotkb:Q57ZJ5|ensembl:ENSP00000281828	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:syfb_human(display_long)|uniprotkb:FARSB(gene name)|psi-mi:FARSB(display_short)|uniprotkb:FARSLB(gene name synonym)|uniprotkb:FRSB(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:HSPC173(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005678.3|refseq:XP_006712232.1|refseq:XP_011508768.1|ensembl:ENSG00000116120(gene)|ensembl:ENST00000281828(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|interpro:IPR040659|interpro:IPR041616|rcsb pdb:3L4G|reactome:R-HSA-379716|refseq:XP_016858599.1|dip:DIP-32869N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:YgMUMEiw+jAUaDK5KomMWi66vn09606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9NZB2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|ensembl:ENSG00000048828(gene)|ensembl:ENST00000277165(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07814	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q01844	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q01968	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-6148898|uniprotkb:O60800|uniprotkb:Q15684|uniprotkb:A6NKI1|uniprotkb:Q9UMA5|uniprotkb:Q4VY09|uniprotkb:Q5JQF2|uniprotkb:A8KAP2|uniprotkb:Q15774|uniprotkb:Q5JQF1|uniprotkb:Q9UJG5|uniprotkb:Q4VY10|uniprotkb:B7ZLX2|ensembl:ENSP00000360154	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ocrl_human(display_long)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym)|uniprotkb:OCRL1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_000267.2|refseq:NP_001578.2|dip:DIP-45092N|ensembl:ENSG00000122126(gene)|ensembl:ENST00000371113(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|go:"GO:0052745"(inositol phosphate phosphatase activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061024"(membrane organization)|interpro:IPR000198(RhoGAP)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031995|interpro:IPR036691|interpro:IPR037787|interpro:IPR037793|mint:Q01968|rcsb pdb:2KIE|rcsb pdb:2QV2|rcsb pdb:3QBT|rcsb pdb:3QIS|rcsb pdb:4CMN|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1855183|reactome:R-HSA-1855204|reactome:R-HSA-432722|reactome:R-HSA-8856828|reactome:R-HSA-9013409|reactome:R-HSA-9013423	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:vbBQzhjgvm07+wOJkWgz+dyEBI49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9BT40	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-749162|uniprotkb:Q15733|uniprotkb:Q9NPJ5|uniprotkb:Q9P2R5|uniprotkb:B2R6I2|uniprotkb:B2R750|uniprotkb:D3DTH8|intact:EBI-28986464|ensembl:ENSP00000413937	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:inp5k_human(display_long)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Skeletal muscle and kidney-enriched inositol phosphatase(gene name synonym)|uniprotkb:INPP5K(gene name)|psi-mi:INPP5K(display_short)|uniprotkb:PPS(gene name synonym)|uniprotkb:Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-4,5-bisphosphate 5-phosphatase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001129114.1|refseq:NP_057616.2|refseq:NP_570122.1|refseq:XP_011522236.1|ensembl:ENST00000320345|ensembl:ENSP00000318476|ensembl:ENST00000406424|ensembl:ENSP00000385177|ensembl:ENSP00000413937|refseq:XP_005256740.1|refseq:XP_016880244.1|refseq:XP_016880245.1|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016312"(inositol bisphosphate phosphatase activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0034594"(phosphatidylinositol trisphosphate phosphatase activity)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046030"(inositol trisphosphate phosphatase activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097178"(ruffle assembly)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|go:"GO:2001153"(positive regulation of renal water transport)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|interpro:IPR041611|reactome:R-HSA-1660499|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|ensembl:ENSG00000132376(gene)|ensembl:ENST00000421807(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005000"(vasopressin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8QwPQ6eR07CZ8XlPtkdG60+KFNA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q14157	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49757	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-915016|uniprotkb:Q6NUQ7|uniprotkb:Q86SY1|uniprotkb:Q8WW73|uniprotkb:Q9UBG1|uniprotkb:Q9UEQ4|uniprotkb:Q9UKE8|uniprotkb:Q9UKE9|uniprotkb:Q9UKF0|uniprotkb:Q9UQJ4|uniprotkb:B4E2B1|uniprotkb:B1P2N7|uniprotkb:B1P2N8|uniprotkb:B1P2N9|uniprotkb:B1P2N5|uniprotkb:B1P2N6|intact:EBI-28966915|ensembl:ENSP00000347169|ensembl:ENSP00000451300	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:numb_human(display_long)|uniprotkb:Protein S171(gene name synonym)|uniprotkb:NUMB(gene name)|psi-mi:NUMB(display_short)|uniprotkb:C14orf41(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENST00000554521|ensembl:ENSP00000450817|ensembl:ENST00000554546|ensembl:ENSP00000452416|ensembl:ENSP00000451300|ensembl:ENST00000555394|ensembl:ENSP00000451625|ensembl:ENST00000555738|ensembl:ENSP00000452069|ensembl:ENST00000557597|ensembl:ENSP00000451117|ensembl:ENST00000559312|ensembl:ENSP00000452888|ensembl:ENST00000560335|ensembl:ENSP00000453209|ensembl:ENSP00000347169|ensembl:ENST00000356296|ensembl:ENSP00000348644|ensembl:ENST00000359560|ensembl:ENSP00000352563|ensembl:ENST00000535282|ensembl:ENSP00000441258|ensembl:ENST00000544991|ensembl:ENSP00000446001|refseq:NP_001307043.1|refseq:NP_001005743.1|refseq:NP_001005744.1|refseq:NP_001005745.1|refseq:NP_003735.3|dip:DIP-37981N|ensembl:ENSG00000133961(gene)|ensembl:ENST00000355058(transcript)|ensembl:ENST00000555238(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021849"(neuroblast division in subventricular zone)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P49757|rcsb pdb:5NJJ|rcsb pdb:5NJK|reactome:R-HSA-2122948|reactome:R-HSA-437239|reactome:R-HSA-5610780|reactome:R-HSA-5632684	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:X+CHBhp67o6ROnf86RCtXlCAaF49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P18085	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1237085|ensembl:ENSP00000306010|uniprotkb:P21371|uniprotkb:B2R7J7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:arf4_human(display_long)|uniprotkb:ARF4(gene name)|psi-mi:ARF4(display_short)|uniprotkb:ARF2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000168374(gene)|ensembl:ENST00000303436(transcript)|refseq:NP_001651.1|dip:DIP-38214N|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0060271"(cilium assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P18085|rcsb pdb:1Z6X|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AN3aBuSStAMrmkqq1HEDQtOiCy49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P53680	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-297662|ensembl:ENSP00000263270|uniprotkb:O75977|uniprotkb:Q6PK67|uniprotkb:B2R4Z4	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ap2s1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit sigma(gene name synonym)|uniprotkb:AP2S1(gene name)|psi-mi:AP2S1(display_short)|uniprotkb:Sigma2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 17 kDa protein(gene name synonym)|uniprotkb:HA2 17 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP17(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP17(gene name synonym)|uniprotkb:AP17(gene name synonym)|uniprotkb:CLAPS2(gene name synonym)|uniprotkb:Clathrin assembly protein 2 sigma small chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit sigma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000042753(gene)|ensembl:ENST00000263270(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027156|rcsb pdb:6URI|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004060.2|refseq:NP_067586.1|refseq:NP_001288005.1|refseq:NP_001288007.1|refseq:NP_001288010.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AJxHeeoCpwPxjsRcAQkiAGaC9k09606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P63313	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2688673|uniprotkb:Q596K9|uniprotkb:P13472|ensembl:ENSP00000233143	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tyb10_human(display_long)|uniprotkb:PTMB10(gene name synonym)|uniprotkb:THYB10(gene name synonym)|uniprotkb:TMSB10(gene name)|psi-mi:TMSB10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_066926.1|ensembl:ENSG00000034510(gene)|ensembl:ENST00000233143(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042989"(sequestering of actin monomers)|interpro:IPR001152(Thymosin beta-4)|interpro:IPR038386	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:oyHgjBTa5Wd0RSnF3dTUPsgPV9w9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q15678	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1237156|uniprotkb:Q5VSI0|ensembl:ENSP00000355923	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ptn14_human(display_long)|uniprotkb:PTPD2(gene name synonym)|uniprotkb:PTPN14(gene name)|psi-mi:PTPN14(display_short)|uniprotkb:PEZ(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase pez(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005392.2|refseq:XP_016857430.1|dip:DIP-38131N|ensembl:ENSG00000152104(gene)|ensembl:ENST00000366956(transcript)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0046825"(regulation of protein export from nucleus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014392(Protein-tyrosine phosphatase, non-receptor type-14, -21)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR041782|rcsb pdb:2BZL|rcsb pdb:6IWD|rcsb pdb:6JJW|reactome:R-HSA-9008059	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:u0TrsaX5tuP97HA2KGYa1WmcvXU9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62258	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q7Z6B7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2481729|uniprotkb:Q9H8A3|uniprotkb:Q9P2P2|ensembl:ENSP00000347198	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:srgp1_human(display_long)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0030336"(negative regulation of cell migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|go:"GO:0005737"(cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|interpro:IPR037451|mint:Q7Z6B7|reactome:R-HSA-428543|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_065813.1|refseq:NP_001333130.1|dip:DIP-53826N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q08AF3	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2822593|uniprotkb:Q8WU54|uniprotkb:Q08AF2|uniprotkb:Q96A82|ensembl:ENSP00000299977	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:slfn5_human(display_long)|uniprotkb:SLFN5(gene name)|psi-mi:SLFN5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_659412.3|ensembl:ENSG00000166750(gene)|ensembl:ENST00000299977(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0030154"(cell differentiation)|interpro:IPR007421(ATPase associated with various cellular activities, AAA-4)|interpro:IPR018647|interpro:IPR027417|interpro:IPR029671|interpro:IPR029684|interpro:IPR038461|rcsb pdb:6RR9|mint:Q08AF3	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:+BZzuyp+fqb1tLg86wpHu/5RPMI9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P35241	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:75lzbINdL0deHtiWY7IwioSh5749606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P55196	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:XP_005267053.1|ensembl:ENST00000392108|ensembl:ENSP00000375956|ensembl:ENST00000392112|ensembl:ENSP00000375960|ensembl:ENST00000400822|ensembl:ENSP00000383623|ensembl:ENSP00000404595|refseq:NP_001278893.1|ensembl:ENSG00000130396(gene)|ensembl:ENST00000447894(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|rcsb pdb:5A6C|reactome:R-HSA-418990|go:"GO:0022409"(positive regulation of cell-cell adhesion)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P49006	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-4289961|uniprotkb:Q5TEE6|uniprotkb:Q6NXS5|uniprotkb:D3DPQ0|ensembl:ENSP00000362638	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mrp_human(display_long)|uniprotkb:MARCKSL1(gene name)|psi-mi:MARCKSL1(display_short)|uniprotkb:MLP(gene name synonym)|uniprotkb:MRP(gene name synonym)|uniprotkb:MARCKS-like protein 1(gene name synonym)|uniprotkb:Macrophage myristoylated alanine-rich C kinase substrate(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000175130(gene)|ensembl:ENST00000329421(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P49006|refseq:NP_075385.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:nkq8hGJINvCHlZJ3alKkDP+wCxk9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q08554	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2371346|uniprotkb:Q9HB01|ensembl:ENSP00000257198	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:dsc1_human(display_long)|uniprotkb:DSC1(gene name)|psi-mi:DSC1(display_short)|uniprotkb:CDHF1(gene name synonym)|uniprotkb:Desmosomal glycoprotein 2/3(gene name synonym)|uniprotkb:Cadherin family member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004939.1|refseq:NP_077739.1|ensembl:ENSG00000134765(gene)|ensembl:ENST00000257198(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030057"(desmosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|rcsb pdb:5IRY|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:dxtPfdDnZFaelPwT5bV8k/ZobSw9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q16527	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2959737|ensembl:ENSP00000310901|ensembl:ENSP00000450056|uniprotkb:Q93030	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:csrp2_human(display_long)|uniprotkb:CSRP2(gene name)|psi-mi:CSRP2(display_short)|uniprotkb:LMO5(gene name synonym)|uniprotkb:SMLIM(gene name synonym)|uniprotkb:Cysteine-rich protein 2(gene name synonym)|uniprotkb:LIM domain only protein 5(gene name synonym)|uniprotkb:Smooth muscle cell LIM protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001312.1|ensembl:ENSG00000175183(gene)|ensembl:ENST00000311083(transcript)|ensembl:ENST00000546966(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0060537"(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001287894.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:nyQ01E4UJb21IE/mZhZjXakJoyo9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P21291	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-3959636|uniprotkb:A8K268|uniprotkb:Q5U0J2|ensembl:ENSP00000345079|ensembl:ENSP00000356275|ensembl:ENSP00000434147|ensembl:ENSP00000436792	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:csrp1_human(display_long)|uniprotkb:CSRP1(gene name)|psi-mi:CSRP1(display_short)|uniprotkb:CSRP(gene name synonym)|uniprotkb:CYRP(gene name synonym)|uniprotkb:Cysteine-rich protein 1(gene name synonym)|uniprotkb:Epididymis luminal protein 141(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001180499.1|refseq:NP_001180500.1|refseq:NP_001180501.1|refseq:NP_004069.1|ensembl:ENSG00000159176(gene)|ensembl:ENST00000367306(transcript)|ensembl:ENST00000532460(transcript)|ensembl:ENST00000533432(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-HSA-5660489|ensembl:ENST00000340006(transcript)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:7mB03gFR0px7OTsYWr2F1XD0U209606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P52943	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-947590|uniprotkb:A1A4U1|uniprotkb:B7Z6C0|uniprotkb:E9PD13|ensembl:ENSP00000328521	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:crip2_human(display_long)|uniprotkb:CRIP2(gene name)|psi-mi:CRIP2(display_short)|uniprotkb:CRP2(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001303.1|refseq:NP_001257766.1|refseq:NP_001257770.1|dip:DIP-49905N|ensembl:ENSG00000182809(gene)|ensembl:ENST00000329146(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2CU8	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:7Lbv0tyZva/ZSPj139n0qxwrmv49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q0VF96	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-3388952|intact:EBI-28971578|ensembl:ENSP00000281282|uniprotkb:Q9C0B4|uniprotkb:Q7Z2L3|uniprotkb:Q695C7|uniprotkb:Q52LR0|uniprotkb:Q96JV2|uniprotkb:Q05BZ4|uniprotkb:Q96MN6	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:cgnl1_human(display_long)|uniprotkb:CGNL1(gene name)|psi-mi:CGNL1(display_short)|uniprotkb:JACOP(gene name synonym)|uniprotkb:KIAA1749(gene name synonym)|uniprotkb:Junction-associated coiled-coil protein(gene name synonym)|uniprotkb:Paracingulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSP00000281282|ensembl:ENSG00000128849(gene)|ensembl:ENST00000281282(transcript)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0016459"(myosin complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR002928(Myosin tail)|refseq:NP_116255.2|refseq:XP_016878175.1|refseq:NP_001239264.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:9YBGN8pBNQZm3tvMb2w0NdXLV0U9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62328	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-712598|uniprotkb:P01253|uniprotkb:P01254|uniprotkb:Q546P5|ensembl:ENSP00000370007|ensembl:ENSP00000370009|ensembl:ENSP00000370010|ensembl:ENSP00000414376|uniprotkb:Q63576|uniprotkb:Q9UE55	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tyb4_human(display_long)|uniprotkb:Fx(gene name synonym)|uniprotkb:TMSB4X(gene name)|psi-mi:TMSB4X(display_short)|uniprotkb:TB4X(gene name synonym)|uniprotkb:THYB4(gene name synonym)|uniprotkb:TMSB4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000205542(gene)|ensembl:ENST00000380633(transcript)|go:"GO:0019899"(enzyme binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|ensembl:ENST00000380635(transcript)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|ensembl:ENST00000380636(transcript)|go:"GO:0042989"(sequestering of actin monomers)|ensembl:ENST00000451311(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905273"(positive regulation of proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001152(Thymosin beta-4)|go:"GO:0005737"(cytoplasm)|interpro:IPR038386|mint:P62328|rcsb pdb:1UY5|go:"GO:0005829"(cytosol)|rcsb pdb:3TU5|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|rcsb pdb:4PL8|rcsb pdb:4PL7|reactome:R-HSA-114608|refseq:NP_066932.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xkqTI8zw7X+xH6HCvkuLtGlNbvs9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q08AE8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1055655|uniprotkb:Q1RMD4|uniprotkb:Q9NQ71|uniprotkb:Q9ULT4|uniprotkb:A8K2B5|uniprotkb:Q8NDP1|uniprotkb:J3KQ50|uniprotkb:J3KQR5|ensembl:ENSP00000387266	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:spir1_human(display_long)|uniprotkb:SPIR1(gene name synonym)|uniprotkb:SPIRE1(gene name)|psi-mi:SPIRE1(display_short)|uniprotkb:KIAA1135(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001122098.1|refseq:NP_001122099.1|refseq:NP_064533.3|ensembl:ENST00000409402(transcript)|ensembl:ENSG00000134278(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045010"(actin nucleation)|go:"GO:0046907"(intracellular transport)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070649"(formin-nucleated actin cable assembly)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011019(KIND)|interpro:IPR029901|interpro:IPR029905|mint:Q08AE8|rcsb pdb:2YLE|rcsb pdb:2YLF|rcsb pdb:3R7G|rcsb pdb:3RBW|go:"GO:0003779"(actin binding)|dip:DIP-42378N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:y/XOE8pHx7hdvdupDmeINEq7L+M9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q13796	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1644065|uniprotkb:B9EIQ7|intact:EBI-28971643|ensembl:ENSP00000370299	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:shrm2_human(display_long)|uniprotkb:SHROOM2(gene name)|psi-mi:SHROOM2(display_short)|uniprotkb:APXL(gene name synonym)|uniprotkb:Apical-like protein(gene name synonym)|uniprotkb:Protein APXL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSP00000370299|refseq:NP_001640.1|refseq:NP_001307592.1|refseq:NP_001307593.1|ensembl:ENSG00000146950(gene)|ensembl:ENST00000380913(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008057"(eye pigment granule organization)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0032401"(establishment of melanosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0043296"(apical junction complex)|go:"GO:0043482"(cellular pigment accumulation)|go:"GO:0043583"(ear development)|go:"GO:0045176"(apical protein localization)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR014799(Apx/shroom, ASD2)|interpro:IPR014800(Apx/shroom, ASD1)|interpro:IPR027685|interpro:IPR027686|interpro:IPR036034|rcsb pdb:5F4Y|rcsb pdb:5F5P|go:"GO:0043010"(camera-type eye development)	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:iZseuKQ3hL6TJYweKq/+cyM5no49606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07737	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q0ZGT2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351705|uniprotkb:B4DPZ7|uniprotkb:A0PJ84|uniprotkb:Q0D2H2|uniprotkb:Q14CC2|uniprotkb:Q14CC3|uniprotkb:Q16081|uniprotkb:Q7Z2X0|uniprotkb:Q96DL0|uniprotkb:Q9Y2V1|intact:EBI-2555043|ensembl:ENSP00000333938	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:nexn_human(display_long)|uniprotkb:F-actin-binding protein(gene name synonym)|uniprotkb:Nelin(gene name synonym)|uniprotkb:NEXN(gene name)|psi-mi:NEXN(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001165780.1|refseq:NP_653174.3|ensembl:ENSG00000162614(gene)|ensembl:ENST00000334785(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0051015"(actin filament binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|mint:Q0ZGT2|go:"GO:0008307"(structural constituent of muscle)|refseq:XP_005271380.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:YtKRiGq1tjrPhdFzpS5TKVn3So89606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O94851	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2804835|uniprotkb:Q7Z3A8|uniprotkb:D3DQW5|uniprotkb:B4DGZ0|uniprotkb:B7Z849|uniprotkb:G3XAC8|uniprotkb:Q5KTR3|uniprotkb:Q5KTR4|ensembl:ENSP00000256194|ensembl:ENSP00000507067	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mica2_human(display_long)|uniprotkb:KIAA0750(gene name synonym)|uniprotkb:MICAL2(gene name)|psi-mi:MICAL2(display_short)|uniprotkb:MICAL2PV1(gene name synonym)|uniprotkb:MICAL2PV2(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001269592.1|refseq:NP_001269593.1|refseq:NP_001269594.1|refseq:NP_001269595.1|refseq:NP_001269596.1|refseq:NP_055447.1|refseq:NP_001333221.1|refseq:NP_001333222.1|refseq:NP_001333223.1|refseq:NP_001333224.1|refseq:NP_001333225.1|refseq:NP_001333226.1|refseq:NP_001333227.1|refseq:NP_001333228.1|refseq:XP_016874078.1|refseq:XP_016874079.1|refseq:XP_016874080.1|ensembl:ENSG00000133816(gene)|ensembl:ENST00000256194(transcript)|ensembl:ENST00000683283(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007507"(heart development)|go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0019417"(sulfur oxidation)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0043914"("NADPH:sulfur oxidoreductase activity")|go:"GO:0046872"(metal ion binding)|go:"GO:0071949"(FAD binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR029939|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2E9K	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:qbQ0zzaskf5owXjOkSPlufxobm89606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q14678	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P46940	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q16658	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351076|uniprotkb:Q96IH1|uniprotkb:A6NI89|uniprotkb:Q96IC5|uniprotkb:Q9BRF1|uniprotkb:B2RE97|ensembl:ENSP00000371798	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fscn1_human(display_long)|uniprotkb:FSCN1(gene name)|psi-mi:FSCN1(display_short)|uniprotkb:FAN1(gene name synonym)|uniprotkb:HSN(gene name synonym)|uniprotkb:SNL(gene name synonym)|uniprotkb:Singed-like protein(gene name synonym)|uniprotkb:55 kDa actin-bundling protein(gene name synonym)|uniprotkb:p55(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0044393"(microspike)|go:"GO:0045296"(cadherin binding)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146|mint:Q16658|rcsb pdb:1DFC|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030035"(microspike assembly)|rcsb pdb:3LLP|refseq:NP_003079.1|ensembl:ENSG00000075618(gene)|ensembl:ENST00000382361(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008144"(obsolete drug binding)|rcsb pdb:3P53|rcsb pdb:4GOV|rcsb pdb:4GOY|rcsb pdb:4GP3|rcsb pdb:6B0T|rcsb pdb:6I0Z|rcsb pdb:6I10|rcsb pdb:6I11|rcsb pdb:6I12|rcsb pdb:6I13|rcsb pdb:6I14|rcsb pdb:6I15|rcsb pdb:6I16|rcsb pdb:6I17|rcsb pdb:6I18|reactome:R-HSA-6785807|rcsb pdb:4GP0|dip:DIP-33171N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:yc9EJDCKGJGGEcEueR/yAY/fxRg9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q13045	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351549|ensembl:ENSP00000491480|ensembl:ENSP00000324573|uniprotkb:B4DIL0|uniprotkb:F5H407|uniprotkb:J3QLG3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:flii_human(display_long)|uniprotkb:FLII(gene name)|psi-mi:FLII(display_short)|uniprotkb:FLIL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002009.1|refseq:NP_001243193.1|ensembl:ENST00000327031(transcript)|ensembl:ENST00000638207(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030239"(myofibril assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR029919|interpro:IPR032675|mint:Q13045|ensembl:ENSG00000177731(gene)|ensembl:ENSG00000284571(gene)|refseq:NP_001243194.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:hzls0Ir+lr0+wNsTUeIURV3fXVQ9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y613	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-348433|ensembl:ENSP00000258201|uniprotkb:Q59F76|uniprotkb:Q6Y1F2|uniprotkb:Q76MS8|uniprotkb:Q8N521	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fhod1_human(display_long)|uniprotkb:FHOD1(gene name)|psi-mi:FHOD1(display_short)|uniprotkb:FHOS(gene name synonym)|uniprotkb:FHOS1(gene name synonym)|uniprotkb:Formin homolog overexpressed in spleen 1(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_037373.2|ensembl:ENSG00000135723(gene)|ensembl:ENST00000258201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007097"(nuclear migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051015"(actin filament binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027647|interpro:IPR041387|interpro:IPR042201|rcsb pdb:3DAD|rcsb pdb:6XF1|rcsb pdb:6XF2|mint:Q9Y613|dip:DIP-31134N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8zGurHJ5FL9gvqZazyRAHElMAdI9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P11171	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1050906|uniprotkb:P11176|uniprotkb:Q14245|uniprotkb:Q5TB35|uniprotkb:Q5VXN8|uniprotkb:Q8IXV9|uniprotkb:Q9Y578|uniprotkb:Q9Y579|uniprotkb:B1ALH8|uniprotkb:B1ALH9|uniprotkb:D3DPM9|uniprotkb:D3DPN0|ensembl:ENSP00000345259|ensembl:ENSP00000362904	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:epb41_human(display_long)|uniprotkb:Band 4.1(gene name synonym)|uniprotkb:EPB4.1(gene name synonym)|uniprotkb:4.1R(gene name synonym)|uniprotkb:EPB41(gene name)|psi-mi:EPB41(display_short)|uniprotkb:E41P(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001159477.1|refseq:NP_001159478.1|refseq:NP_004428.1|refseq:NP_976217.1|refseq:XP_016856078.1|refseq:XP_005245818.1|refseq:XP_005245821.1|ensembl:ENSG00000159023(gene)|ensembl:ENST00000343067(transcript)|ensembl:ENST00000373798(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045171"(intercellular bridge)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099738"(cell cortex region)|go:"GO:1904478"(regulation of intestinal absorption)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR021187|interpro:IPR029071|interpro:IPR035963|mint:P11171|rcsb pdb:1GG3|rcsb pdb:2RQ1|rcsb pdb:3QIJ|reactome:R-HSA-6794361|dip:DIP-17032N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ZCaM+kjScfGP23wRkFRwVyxOyvk9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9BPX5	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-711189|ensembl:ENSP00000259477|ensembl:ENSP00000345361|uniprotkb:Q7Z523	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:arp5l_human(display_long)|uniprotkb:Arp2/3 complex 16 kDa subunit 2(gene name synonym)|uniprotkb:ARPC5L(gene name)|psi-mi:ARPC5L(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112240.1|ensembl:ENSG00000136950(gene)|ensembl:ENST00000259477(transcript)|ensembl:ENST00000353214(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0016477"(cell migration)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR030075|interpro:IPR036743|mint:Q9BPX5|rcsb pdb:6YW6|dip:DIP-50399N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:JVproBu8rIrnlk39yXPC+ZrvoOk9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P12814	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P63261	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q3ZCM7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9BQE3	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1103245|ensembl:ENSP00000301072	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P06753	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9NYL9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352614|ensembl:ENSP00000308753|uniprotkb:Q9NT43|uniprotkb:Q9NZR0|uniprotkb:B2R6G7	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tmod3_human(display_long)|uniprotkb:TMOD3(gene name)|psi-mi:TMOD3(display_short)|uniprotkb:Ubiquitous tropomodulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000138594(gene)|ensembl:ENST00000308580(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|refseq:NP_055362.1|go:"GO:0048821"(erythrocyte development)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR004934(Tropomodulin)|interpro:IPR030133|interpro:IPR032675|mint:Q9NYL9|reactome:R-HSA-390522|reactome:R-HSA-9013418|reactome:R-HSA-9696264|refseq:XP_016877576.1|refseq:XP_016877577.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:crEfCAAepSPAE8ByBpD4Sr14P5I9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O75347	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2686341|uniprotkb:B4DT30|ensembl:ENSP00000369736	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tbca_human(display_long)|uniprotkb:TCP1-chaperonin cofactor A(gene name synonym)|uniprotkb:Tubulin-folding cofactor A(gene name synonym)|uniprotkb:TBCA(gene name)|psi-mi:TBCA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004598.1|refseq:NP_001284667.1|ensembl:ENSG00000171530(gene)|ensembl:ENST00000380377(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004226(Tubulin binding cofactor A)|interpro:IPR036126|mint:O75347|rcsb pdb:1H7C|reactome:R-HSA-389977	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:hETmNl4lTAEyZ89oOKuhkah5vmQ9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UM54	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O00159	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-350423|uniprotkb:Q6NVJ7|intact:EBI-1045431|uniprotkb:Q86Y95|uniprotkb:Q4LE56|ensembl:ENSP00000496954	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:myo1c_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:Myosin I beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0005829"(cytosol)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|refseq:NP_001074248.1|refseq:NP_001074419.1|refseq:NP_203693.3|ensembl:ENSG00000197879(gene)|ensembl:ENST00000648651(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O00159|rcsb pdb:4BYF|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-5250924|reactome:R-HSA-9662360|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|reactome:R-HSA-9662361|reactome:R-HSA-9664422|dip:DIP-33109N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:g6wQN0OVKjd3T1kOebWFcqWNzNA9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P35749	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1052928|uniprotkb:O00396|uniprotkb:O94944|uniprotkb:P78422|uniprotkb:Q3MNF0|uniprotkb:Q3MNF1|uniprotkb:Q3MIV8|uniprotkb:D2JYH7|ensembl:ENSP00000300036|ensembl:ENSP00000488461	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:myh11_human(display_long)|uniprotkb:Myosin heavy chain 11(gene name synonym)|uniprotkb:Myosin heavy chain, smooth muscle isoform(gene name synonym)|uniprotkb:SMMHC(gene name synonym)|uniprotkb:MYH11(gene name)|psi-mi:MYH11(display_short)|uniprotkb:KIAA0866(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	dip:DIP-47268N|refseq:NP_002465.1|refseq:NP_001035202.1|refseq:NP_001035203.1|refseq:NP_074035.1|ensembl:ENSG00000133392(gene)|ensembl:ENSG00000276480(gene)|ensembl:ENST00000300036(transcript)|ensembl:ENST00000634050(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0032982"(myosin filament)|go:"GO:0042470"(melanosome)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35749|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016878739.1	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:iE4qZJHXiIfxtk9An/7T4DKbwIU9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O60333	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q12756	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O43896	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1644048|uniprotkb:O75186|uniprotkb:Q5U618|uniprotkb:D3DTL6|ensembl:ENSP00000320821	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:kif1c_human(display_long)|uniprotkb:KIF1C(gene name)|psi-mi:KIF1C(display_short)|uniprotkb:KIAA0706(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006603.2|refseq:XP_005256481.1|dip:DIP-40376N|ensembl:ENSG00000129250(gene)|ensembl:ENST00000320785(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|mint:O43896|rcsb pdb:2G1L|reactome:R-HSA-6811434|reactome:R-HSA-983189	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:AeG87fdDj70xFfsQCPuXA9iiubo9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q8IYT4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1044332|ensembl:ENSP00000348478|ensembl:ENSP00000508137	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:katl2_human(display_long)|uniprotkb:p60 katanin-like 2(gene name synonym)|uniprotkb:KATNAL2(gene name)|psi-mi:KATNAL2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099538|imex:IM-25792-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112593.2|refseq:XP_006722617.1|ensembl:ENSG00000167216(gene)|ensembl:ENST00000356157(transcript)|ensembl:ENST00000683218(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR027417|interpro:IPR027497|interpro:IPR041569	-	-	-	figure legend:supplementary table 5|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:2k+M09zbS1SB029s47A1CpuD+ZY9606	rigid:7lV9iJTUj09TCgrnwgn9an6X19M	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UQ80	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07858	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000503300|ensembl:ENSP00000503435|ensembl:ENSP00000503487|ensembl:ENSP00000503513|ensembl:ENSP00000503578|ensembl:ENSP00000503608|ensembl:ENSP00000503652|ensembl:ENSP00000503674|ensembl:ENSP00000503858|ensembl:ENSP00000503909|ensembl:ENSP00000504161|ensembl:ENSP00000504226|ensembl:ENSP00000504336|ensembl:ENSP00000504480|ensembl:ENSP00000504638|ensembl:ENSP00000504659|ensembl:ENSP00000504797|ensembl:ENSP00000503280|ensembl:ENSP00000342070|ensembl:ENSP00000345672|ensembl:ENSP00000431143|ensembl:ENSP00000431518|ensembl:ENSP00000432077|ensembl:ENSP00000432244|ensembl:ENSP00000432408|ensembl:ENSP00000433215|ensembl:ENSP00000433379|ensembl:ENSP00000433929|ensembl:ENSP00000434217|ensembl:ENSP00000434725|ensembl:ENSP00000435074|ensembl:ENSP00000435105|ensembl:ENSP00000435260|ensembl:ENSP00000435886|ensembl:ENSP00000473301|ensembl:ENSP00000502963|ensembl:ENSP00000503006|ensembl:ENSP00000503052|ensembl:ENSP00000503078|ensembl:ENSP00000503174	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|ensembl:ENST00000345125(transcript)|ensembl:ENST00000353047(transcript)|ensembl:ENST00000524654(transcript)|ensembl:ENST00000526481(transcript)|ensembl:ENST00000526645(transcript)|ensembl:ENST00000527215(transcript)|ensembl:ENST00000534382(transcript)|ensembl:ENST00000527243(transcript)|ensembl:ENST00000534510(transcript)|ensembl:ENST00000676691(transcript)|ensembl:ENST00000676755(transcript)|ensembl:ENST00000676825(transcript)|ensembl:ENST00000676843(transcript)|ensembl:ENST00000676952(transcript)|ensembl:ENST00000677082(transcript)|ensembl:ENST00000677366(transcript)|ensembl:ENST00000677415(transcript)|ensembl:ENST00000528965(transcript)|ensembl:ENST00000530296(transcript)|ensembl:ENST00000530640(transcript)|ensembl:ENST00000677418(transcript)|ensembl:ENST00000677544(transcript)|ensembl:ENST00000677650(transcript)|ensembl:ENST00000677671(transcript)|ensembl:ENST00000677819(transcript)|ensembl:ENST00000677873(transcript)|ensembl:ENST00000678092(transcript)|ensembl:ENST00000678145(transcript)|ensembl:ENST00000678242(transcript)|ensembl:ENST00000531089(transcript)|ensembl:ENST00000678357(transcript)|ensembl:ENST00000531502(transcript)|ensembl:ENST00000678615(transcript)|ensembl:ENST00000532392(transcript)|ensembl:ENST00000678929(transcript)|ensembl:ENST00000532656(transcript)|ensembl:ENST00000533455(transcript)|ensembl:ENST00000679051(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042981"(regulation of apoptotic process)|ensembl:ENST00000679128(transcript)|go:"GO:0043394"(proteoglycan binding)|ensembl:ENST00000679140(transcript)|go:"GO:0046697"(decidualization)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|ensembl:ENSG00000164733(gene)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1CSB|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:XP_006716307.1|refseq:XP_006716308.1|dip:DIP-42785N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07384	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1542113|uniprotkb:Q2TTR0|uniprotkb:Q6DHV4|ensembl:ENSP00000279247|ensembl:ENSP00000431686|ensembl:ENSP00000431984|ensembl:ENSP00000434176|ensembl:ENSP00000435272	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:can1_human(display_long)|uniprotkb:CAPN1(gene name)|psi-mi:CAPN1(display_short)|uniprotkb:CANPL1(gene name synonym)|uniprotkb:Calpain-1 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 1(gene name synonym)|uniprotkb:Calpain mu-type(gene name synonym)|uniprotkb:Micromolar-calpain(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 30 protein(gene name synonym)|uniprotkb:PIG30(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:XP_006718761.1|refseq:NP_001185797.1|refseq:NP_001185798.1|refseq:NP_005177.2|refseq:XP_011543594.1|ensembl:ENSG00000014216(gene)|ensembl:ENST00000279247(transcript)|ensembl:ENST00000524773(transcript)|ensembl:ENST00000527323(transcript)|ensembl:ENST00000533129(transcript)|ensembl:ENST00000533820(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060056"(mammary gland involution)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097264"(self proteolysis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029643|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P07384|rcsb pdb:1ZCM|rcsb pdb:2ARY|reactome:R-HSA-1474228|reactome:R-HSA-6798695|reactome:R-HSA-6809371|reactome:R-HSA-8862803	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:hLf5vu04E7/yonXBb9VIZThbcxk9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9H299	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-5234893|uniprotkb:Q5T122|ensembl:ENSP00000270792	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sh3l3_human(display_long)|uniprotkb:SH3BGRL3(gene name)|psi-mi:SH3BGRL3(display_short)|uniprotkb:SH3 domain-binding protein 1(gene name synonym)|uniprotkb:P1725(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112576.1|ensembl:ENSG00000142669(gene)|ensembl:ENST00000270792(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016604"(nuclear body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006993(SH3-binding, glutamic acid-rich protein)|interpro:IPR036249|rcsb pdb:1SJ6	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:mD13ce5qQqvgJtLXWU+/Ssd4Rks9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q92900	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P08708	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-358255|uniprotkb:B2R4U4|intact:EBI-8012092|intact:EBI-11603362|intact:MINT-8395037|uniprotkb:P0CW22|ensembl:ENSP00000483755|ensembl:ENSP00000498019	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rs17_human(display_long)|uniprotkb:RPS17(gene name)|psi-mi:RPS17(display_short)|uniprotkb:Small ribosomal subunit protein eS17(gene name synonym)|uniprotkb:RPS17L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001012.1|ensembl:ENSG00000182774(gene)|ensembl:ENSG00000278229(gene)|ensembl:ENST00000617731(transcript)|ensembl:ENST00000647841(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001210(Ribosomal protein S17e)|interpro:IPR018273|interpro:IPR036401|mint:P08708|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|go:"GO:0034101"(erythrocyte homeostasis)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:st+xQCXdSObiy6cJD1cSx869V289606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P62495	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-750990|intact:EBI-1047744|uniprotkb:B2R6B4|uniprotkb:D3DQC1|uniprotkb:P46055|uniprotkb:Q5M7Z7|uniprotkb:Q96CG1|ensembl:ENSP00000353741	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:erf1_human(display_long)|uniprotkb:ETF1(gene name)|psi-mi:ETF1(display_short)|uniprotkb:ERF1(gene name synonym)|uniprotkb:Protein Cl1(gene name synonym)|uniprotkb:RF1(gene name synonym)|uniprotkb:SUP45L1(gene name synonym)|uniprotkb:TB3-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004721.1|refseq:NP_001243231.1|refseq:NP_001278903.1|refseq:NP_001278904.1|refseq:XP_005271978.1|ensembl:ENSG00000120705(gene)|ensembl:ENST00000360541(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006415"(translational termination)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0008079"(translation termination factor activity)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0018444"(translation release factor complex)|go:"GO:0043022"(ribosome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR024049|interpro:IPR029064|interpro:IPR042226|mint:P62495|rcsb pdb:1DT9|rcsb pdb:2HST|rcsb pdb:2KTU|rcsb pdb:2KTV|rcsb pdb:2LGT|rcsb pdb:2LLX|rcsb pdb:2MQ6|rcsb pdb:2MQ9|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3JAG|rcsb pdb:3JAH|rcsb pdb:3JAI|rcsb pdb:4D5N|rcsb pdb:4D61|rcsb pdb:5A8L|rcsb pdb:5LZT|rcsb pdb:5LZU|rcsb pdb:5LZV|rcsb pdb:6D90|rcsb pdb:6IP8|rcsb pdb:6XA1|rcsb pdb:6ZME|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:vUI2Eq2wx++5VxZ2MK1EQ0jnWMI9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q15369	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q7KZF4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O60869	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P61011	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2854176|uniprotkb:B2R759|uniprotkb:P13624|uniprotkb:B4DUW6|ensembl:ENSP00000216774|ensembl:ENSP00000451818|ensembl:ENSP00000504518|ensembl:ENSP00000504673	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:srp54_human(display_long)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:XP_011535408.1|refseq:NP_001139754.1|refseq:NP_003127.1|ensembl:ENSG00000100883(gene)|ensembl:ENST00000678963(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019003"(GDP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|mint:P61011|rcsb pdb:1MFQ|rcsb pdb:1QB2|rcsb pdb:5L3Q|rcsb pdb:6Y2Z|rcsb pdb:6Y30|rcsb pdb:6Y31|rcsb pdb:6Y32|rcsb pdb:7NFX|ensembl:ENST00000216774(transcript)|reactome:R-HSA-1799339|ensembl:ENST00000556994(transcript)|ensembl:ENST00000677647(transcript)	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8iRlU+NvhLEJNv7B90TAZyRqwiY9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q8TCS8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1052020|uniprotkb:Q53SU0|uniprotkb:Q68CN1|uniprotkb:Q7Z7D1|uniprotkb:Q8IWX1|uniprotkb:Q96T05|uniprotkb:Q9BRU3|uniprotkb:Q9BVX0|ensembl:ENSP00000393953|ensembl:ENSP00000400646	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pnpt1_human(display_long)|uniprotkb:Polynucleotide phosphorylase 1(gene name synonym)|uniprotkb:Polynucleotide phosphorylase-like protein(gene name synonym)|uniprotkb:PNPase old-35(gene name synonym)|uniprotkb:3'-5' RNA exonuclease OLD35(gene name synonym)|uniprotkb:PNPT1(gene name)|psi-mi:PNPT1(display_short)|uniprotkb:PNPASE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_149100.2|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0097222"(mitochondrial mRNA polyadenylation)|go:"GO:0097421"(liver regeneration)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR003029(S1, RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR020568|interpro:IPR022967|interpro:IPR027408|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|rcsb pdb:3U1K|rcsb pdb:5ZF6|ensembl:ENSG00000138035(gene)|ensembl:ENST00000415374(transcript)|ensembl:ENST00000447944(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000957"(mitochondrial RNA catabolic process)|go:"GO:0000958"(mitochondrial mRNA catabolic process)|go:"GO:0000962"(positive regulation of mitochondrial RNA catabolic process)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0000965"(mitochondrial RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0034046"("poly(G) binding")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035927"(RNA import into mitochondrion)|go:"GO:0035928"(rRNA import into mitochondrion)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0045025"(mitochondrial degradosome)|go:"GO:0004654"(polyribonucleotide nucleotidyltransferase activity)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060416"(response to growth hormone)|dip:DIP-50226N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:W9hr1vfWv1b0v4xfMYatfKfOMcg9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9NSD9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-353803|uniprotkb:B4DFM0|uniprotkb:O95708|uniprotkb:Q9NZZ6|uniprotkb:Q4ZFX1|uniprotkb:Q57ZJ5|ensembl:ENSP00000281828	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:syfb_human(display_long)|uniprotkb:FARSB(gene name)|psi-mi:FARSB(display_short)|uniprotkb:FARSLB(gene name synonym)|uniprotkb:FRSB(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:HSPC173(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005678.3|refseq:XP_006712232.1|refseq:XP_011508768.1|ensembl:ENSG00000116120(gene)|ensembl:ENST00000281828(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|interpro:IPR040659|interpro:IPR041616|rcsb pdb:3L4G|reactome:R-HSA-379716|refseq:XP_016858599.1|dip:DIP-32869N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:YgMUMEiw+jAUaDK5KomMWi66vn09606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P41208	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1789926|uniprotkb:Q53XW1|uniprotkb:B2R4T4|ensembl:ENSP00000359300	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:cetn2_human(display_long)|uniprotkb:CETN2(gene name)|psi-mi:CETN2(display_short)|uniprotkb:CALT(gene name synonym)|uniprotkb:CEN2(gene name synonym)|uniprotkb:Caltractin isoform 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004335.1|ensembl:ENSG00000147400(gene)|ensembl:ENST00000370277(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007099"(centriole replication)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032795"(heterotrimeric G-protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045177"(apical part of cell)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071942"(XPC complex)|go:"GO:0097729"(9+2 motile cilium)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR037629|rcsb pdb:1M39|rcsb pdb:1ZMZ|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2K2I|rcsb pdb:2OBH|reactome:R-HSA-2565942|reactome:R-HSA-3108214|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-8854518	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:gOH/cxPm4HW7g94+UYIAAipqXyg9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96RF0	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-298169|uniprotkb:Q05BB3|uniprotkb:Q0VG02|ensembl:ENSP00000342276|uniprotkb:B4E2B3|uniprotkb:H7BXX3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:snx18_human(display_long)|uniprotkb:SNX18(gene name)|psi-mi:SNX18(display_short)|uniprotkb:SH3 and PX domain-containing protein 3B(gene name synonym)|uniprotkb:SH3PXD3B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001096045.1|refseq:NP_001138899.1|refseq:NP_443102.2|ensembl:ENSG00000178996(gene)|go:"GO:0006897"(endocytosis)|ensembl:ENST00000343017(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028646|interpro:IPR035557|interpro:IPR035703|interpro:IPR036028|interpro:IPR036871|mint:Q96RF0|reactome:R-HSA-8856828	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:HpHLfTZ0EfhC6oMHeSr1GCgZaI49606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q00688	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1044081|uniprotkb:Q14317|ensembl:ENSP00000216330|ensembl:ENSP00000379374|uniprotkb:B2R4Q9	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fkbp3_human(display_long)|uniprotkb:FKBP3(gene name)|psi-mi:FKBP3(display_short)|uniprotkb:FKBP25(gene name synonym)|uniprotkb:FK506-binding protein 3(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP25(gene name synonym)|uniprotkb:Rapamycin-selective 25 kDa immunophilin(gene name synonym)|uniprotkb:25 kDa FK506-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002004.1|ensembl:ENSG00000100442(gene)|ensembl:ENST00000216330(transcript)|ensembl:ENST00000396062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR041200|interpro:IPR043368|mint:Q00688|rcsb pdb:1PBK|rcsb pdb:2KFV|rcsb pdb:2MPH|rcsb pdb:5D75|rcsb pdb:5GPG|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xU5FDlTZzy8veAtOaoLtQMeBsr09606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y6I3	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-713198|intact:EBI-28967658|ensembl:ENSP00000270460|uniprotkb:Q86ST3|uniprotkb:Q9HA18	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:epn1_human(display_long)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)|uniprotkb:EH domain-binding mitotic phosphoprotein(gene name synonym)|uniprotkb:EPN1(gene name)|psi-mi:EPN1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048568"(embryonic organ development)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q9Y6I3|rcsb pdb:1INZ|rcsb pdb:1KYD|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|ensembl:ENSG00000063245(gene)|ensembl:ENST00000270460(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|ensembl:ENST00000085079|ensembl:ENSP00000085079|ensembl:ENSP00000270460|ensembl:ENST00000411543|ensembl:ENSP00000406209|refseq:NP_001123543.1|refseq:NP_001123544.1|refseq:NP_037465.2|refseq:XP_005258886.1|refseq:XP_016882211.1|refseq:XP_011525183.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:mp6MIJYGUJryy3Lk5coFqvOt55c9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q16527	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2959737|ensembl:ENSP00000310901|ensembl:ENSP00000450056|uniprotkb:Q93030	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:csrp2_human(display_long)|uniprotkb:CSRP2(gene name)|psi-mi:CSRP2(display_short)|uniprotkb:LMO5(gene name synonym)|uniprotkb:SMLIM(gene name synonym)|uniprotkb:Cysteine-rich protein 2(gene name synonym)|uniprotkb:LIM domain only protein 5(gene name synonym)|uniprotkb:Smooth muscle cell LIM protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001312.1|ensembl:ENSG00000175183(gene)|ensembl:ENST00000311083(transcript)|ensembl:ENST00000546966(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0060537"(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001287894.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:nyQ01E4UJb21IE/mZhZjXakJoyo9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q0VF96	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-3388952|intact:EBI-28971578|ensembl:ENSP00000281282|uniprotkb:Q9C0B4|uniprotkb:Q7Z2L3|uniprotkb:Q695C7|uniprotkb:Q52LR0|uniprotkb:Q96JV2|uniprotkb:Q05BZ4|uniprotkb:Q96MN6	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:cgnl1_human(display_long)|uniprotkb:CGNL1(gene name)|psi-mi:CGNL1(display_short)|uniprotkb:JACOP(gene name synonym)|uniprotkb:KIAA1749(gene name synonym)|uniprotkb:Junction-associated coiled-coil protein(gene name synonym)|uniprotkb:Paracingulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSP00000281282|ensembl:ENSG00000128849(gene)|ensembl:ENST00000281282(transcript)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0016459"(myosin complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR002928(Myosin tail)|refseq:NP_116255.2|refseq:XP_016878175.1|refseq:NP_001239264.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:9YBGN8pBNQZm3tvMb2w0NdXLV0U9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q01082	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q13813	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q6NYC8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2557469|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|uniprotkb:A2AB01|uniprotkb:Q6ZTV1|ensembl:ENSP00000274853|ensembl:ENSP00000373067|ensembl:ENSP00000382150|ensembl:ENSP00000383400|ensembl:ENSP00000388790|ensembl:ENSP00000400129|ensembl:ENSP00000400990|ensembl:ENSP00000404066|ensembl:ENSP00000405234|ensembl:ENSP00000412456|ensembl:ENSP00000413596|ensembl:ENSP00000416648|ensembl:ENSP00000480270	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112(gene)|ensembl:ENSG00000206485(gene)|ensembl:ENSG00000225060(gene)|ensembl:ENSG00000229998(gene)|ensembl:ENST00000274853(transcript)|ensembl:ENST00000383573(transcript)|ensembl:ENST00000399199(transcript)|ensembl:ENST00000400554(transcript)|ensembl:ENST00000437121(transcript)|ensembl:ENST00000438815(transcript)|ensembl:ENST00000438945(transcript)|ensembl:ENSG00000230341(gene)|ensembl:ENST00000443517(transcript)|ensembl:ENSG00000234000(gene)|ensembl:ENST00000444206(transcript)|ensembl:ENST00000449705(transcript)|ensembl:ENST00000451544(transcript)|ensembl:ENST00000455935(transcript)|ensembl:ENST00000615527(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O75369	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q14247	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O15085	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-311099|intact:EBI-28988539|ensembl:ENSP00000354644|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_055599.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_937879.1|ensembl:ENSP00000354644|ensembl:ENST00000368194|ensembl:ENSP00000357177|dip:DIP-31622N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9UEY8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2838698|uniprotkb:Q9UEY7|uniprotkb:O43243|uniprotkb:Q92773|uniprotkb:Q5VU09|uniprotkb:D3DRA8|intact:EBI-28975834|ensembl:ENSP00000348381	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:addg_human(display_long)|uniprotkb:ADD3(gene name)|psi-mi:ADD3(display_short)|uniprotkb:ADDL(gene name synonym)|uniprotkb:Adducin-like protein 70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENST00000277900|ensembl:ENSP00000277900|ensembl:ENSP00000348381|ensembl:ENST00000360162|ensembl:ENSP00000353286|refseq:NP_001307520.1|refseq:NP_001307521.1|refseq:NP_001307522.1|refseq:NP_001307523.1|refseq:NP_001112.2|refseq:NP_058432.1|refseq:NP_063968.1|interpro:IPR036409|mint:Q9UEY8|reactome:R-HSA-5223345|reactome:R-HSA-9013405|reactome:R-HSA-9035034|ensembl:ENSG00000148700(gene)|ensembl:ENST00000356080(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR027772	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:10ZAHAI90VaVf/xUxFcNVX5cIts9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q96FS4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1054981|uniprotkb:O14518|uniprotkb:O60484|uniprotkb:O60618|uniprotkb:Q2YD83|ensembl:ENSP00000377771|ensembl:ENSP00000436269	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sipa1_human(display_long)|uniprotkb:GTPase-activating protein Spa-1(gene name synonym)|uniprotkb:p130 SPA-1(gene name synonym)|uniprotkb:SIPA1(gene name)|psi-mi:SIPA1(display_short)|uniprotkb:SPA1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006738.3|refseq:NP_694985.29|refseq:XP_011543516.1|refseq:XP_005274246.1|ensembl:ENSP00000377771|ensembl:ENSP00000436269|ensembl:ENST00000394224(transcript)|ensembl:ENST00000534313(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|ensembl:ENSG00000213445(gene)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042631"(cellular response to water deprivation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035974|interpro:IPR036034|mint:Q96FS4|reactome:R-HSA-392517	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:N5g/PMrgPEjYn5Cqv5uo0cAMPJI9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:Q9Y2D5	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1754555|uniprotkb:Q9UG26|uniprotkb:B1ALX9|uniprotkb:B2RTU4|uniprotkb:B3KQ00|uniprotkb:B4DTZ2|uniprotkb:B7ZW07|uniprotkb:B9EJB5	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:akap2_human(display_long)|uniprotkb:AKAP2(gene name)|psi-mi:AKAP2(display_short)|uniprotkb:KIAA0920(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP-KL(gene name synonym)|uniprotkb:PRKA2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15099687|imex:IM-25792-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001004065.2|refseq:NP_001130034.1|refseq:NP_001185585.1|refseq:NP_009134.1|refseq:NP_671492.1|interpro:IPR029304	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/06/30	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xfHb6tD0ToXJPHpl4MlbKczjzSg9606	rigid:THeFZcpNpskckJi8UL+E3b1eUmc	false	mutation:179-179,192-192,234-234,287-287,306-306,327-327,362-362,372-372,387-387,410-410,249-249,267-267,128-128,115-115,165-165	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:O15078	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q9BZF9	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-350510|uniprotkb:Q14DD3|uniprotkb:Q8N3B8|uniprotkb:Q9HCL1|uniprotkb:Q9NWC6|uniprotkb:G3XAG2|uniprotkb:Q96NH6|intact:EBI-10977773|ensembl:ENSP00000314556	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:uaca_human(display_long)|uniprotkb:UACA(gene name)|psi-mi:UACA(display_short)|uniprotkb:KIAA1561(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001008225.1|refseq:NP_060473.2|dip:DIP-33117N|ensembl:ENSG00000137831(gene)|ensembl:ENST00000322954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030227|interpro:IPR036770|mint:Q9BZF9|reactome:R-HSA-9013407|reactome:R-HSA-9627069	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:F58VkGk2DBsUUrB+wgknUFZhJ+E9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q8IVG5	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2855510|uniprotkb:Q2TV75|uniprotkb:Q8IWI4|uniprotkb:Q2TV71|uniprotkb:A4D1G8|uniprotkb:A0PJG8|uniprotkb:Q8N3L9|uniprotkb:Q2UZV8|uniprotkb:A0JP23|uniprotkb:Q8N875|uniprotkb:A0JP24|uniprotkb:D6W5Q6|ensembl:ENSP00000326247|ensembl:ENSP00000405760|ensembl:ENSP00000408796	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sam9l_human(display_long)|uniprotkb:SAMD9L(gene name)|psi-mi:SAMD9L(display_short)|uniprotkb:C7orf6(gene name synonym)|uniprotkb:DRIF2(gene name synonym)|uniprotkb:KIAA2005(gene name synonym)|uniprotkb:UEF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001290425.1|refseq:NP_001290426.1|refseq:NP_001290427.1|refseq:NP_001290429.1|refseq:XP_011514205.1|refseq:XP_006715953.1|refseq:NP_689916.2|refseq:XP_016867311.1|refseq:XP_016867312.1|refseq:XP_005250250.1|ensembl:ENSG00000177409(gene)|ensembl:ENST00000318238(transcript)|ensembl:ENST00000411955(transcript)|ensembl:ENST00000437805(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8IVG5	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:LeLNrbdYVE3Ch9qGEB0dmf24wMU9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:P07858	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000503300|ensembl:ENSP00000503435|ensembl:ENSP00000503487|ensembl:ENSP00000503513|ensembl:ENSP00000503578|ensembl:ENSP00000503608|ensembl:ENSP00000503652|ensembl:ENSP00000503674|ensembl:ENSP00000503858|ensembl:ENSP00000503909|ensembl:ENSP00000504161|ensembl:ENSP00000504226|ensembl:ENSP00000504336|ensembl:ENSP00000504480|ensembl:ENSP00000504638|ensembl:ENSP00000504659|ensembl:ENSP00000504797|ensembl:ENSP00000503280|ensembl:ENSP00000342070|ensembl:ENSP00000345672|ensembl:ENSP00000431143|ensembl:ENSP00000431518|ensembl:ENSP00000432077|ensembl:ENSP00000432244|ensembl:ENSP00000432408|ensembl:ENSP00000433215|ensembl:ENSP00000433379|ensembl:ENSP00000433929|ensembl:ENSP00000434217|ensembl:ENSP00000434725|ensembl:ENSP00000435074|ensembl:ENSP00000435105|ensembl:ENSP00000435260|ensembl:ENSP00000435886|ensembl:ENSP00000473301|ensembl:ENSP00000502963|ensembl:ENSP00000503006|ensembl:ENSP00000503052|ensembl:ENSP00000503078|ensembl:ENSP00000503174	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|ensembl:ENST00000345125(transcript)|ensembl:ENST00000353047(transcript)|ensembl:ENST00000524654(transcript)|ensembl:ENST00000526481(transcript)|ensembl:ENST00000526645(transcript)|ensembl:ENST00000527215(transcript)|ensembl:ENST00000534382(transcript)|ensembl:ENST00000527243(transcript)|ensembl:ENST00000534510(transcript)|ensembl:ENST00000676691(transcript)|ensembl:ENST00000676755(transcript)|ensembl:ENST00000676825(transcript)|ensembl:ENST00000676843(transcript)|ensembl:ENST00000676952(transcript)|ensembl:ENST00000677082(transcript)|ensembl:ENST00000677366(transcript)|ensembl:ENST00000677415(transcript)|ensembl:ENST00000528965(transcript)|ensembl:ENST00000530296(transcript)|ensembl:ENST00000530640(transcript)|ensembl:ENST00000677418(transcript)|ensembl:ENST00000677544(transcript)|ensembl:ENST00000677650(transcript)|ensembl:ENST00000677671(transcript)|ensembl:ENST00000677819(transcript)|ensembl:ENST00000677873(transcript)|ensembl:ENST00000678092(transcript)|ensembl:ENST00000678145(transcript)|ensembl:ENST00000678242(transcript)|ensembl:ENST00000531089(transcript)|ensembl:ENST00000678357(transcript)|ensembl:ENST00000531502(transcript)|ensembl:ENST00000678615(transcript)|ensembl:ENST00000532392(transcript)|ensembl:ENST00000678929(transcript)|ensembl:ENST00000532656(transcript)|ensembl:ENST00000533455(transcript)|ensembl:ENST00000679051(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042981"(regulation of apoptotic process)|ensembl:ENST00000679128(transcript)|go:"GO:0043394"(proteoglycan binding)|ensembl:ENST00000679140(transcript)|go:"GO:0046697"(decidualization)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|ensembl:ENSG00000164733(gene)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1CSB|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:XP_006716307.1|refseq:XP_006716308.1|dip:DIP-42785N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:P07384	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1542113|uniprotkb:Q2TTR0|uniprotkb:Q6DHV4|ensembl:ENSP00000279247|ensembl:ENSP00000431686|ensembl:ENSP00000431984|ensembl:ENSP00000434176|ensembl:ENSP00000435272	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:can1_human(display_long)|uniprotkb:CAPN1(gene name)|psi-mi:CAPN1(display_short)|uniprotkb:CANPL1(gene name synonym)|uniprotkb:Calpain-1 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 1(gene name synonym)|uniprotkb:Calpain mu-type(gene name synonym)|uniprotkb:Micromolar-calpain(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 30 protein(gene name synonym)|uniprotkb:PIG30(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:XP_006718761.1|refseq:NP_001185797.1|refseq:NP_001185798.1|refseq:NP_005177.2|refseq:XP_011543594.1|ensembl:ENSG00000014216(gene)|ensembl:ENST00000279247(transcript)|ensembl:ENST00000524773(transcript)|ensembl:ENST00000527323(transcript)|ensembl:ENST00000533129(transcript)|ensembl:ENST00000533820(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060056"(mammary gland involution)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097264"(self proteolysis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029643|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P07384|rcsb pdb:1ZCM|rcsb pdb:2ARY|reactome:R-HSA-1474228|reactome:R-HSA-6798695|reactome:R-HSA-6809371|reactome:R-HSA-8862803	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:hLf5vu04E7/yonXBb9VIZThbcxk9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q9H299	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-5234893|uniprotkb:Q5T122|ensembl:ENSP00000270792	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sh3l3_human(display_long)|uniprotkb:SH3BGRL3(gene name)|psi-mi:SH3BGRL3(display_short)|uniprotkb:SH3 domain-binding protein 1(gene name synonym)|uniprotkb:P1725(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_112576.1|ensembl:ENSG00000142669(gene)|ensembl:ENST00000270792(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016604"(nuclear body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006993(SH3-binding, glutamic acid-rich protein)|interpro:IPR036249|rcsb pdb:1SJ6	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:mD13ce5qQqvgJtLXWU+/Ssd4Rks9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:P62753	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:beDuXCIqL99V9JlVfpzx7MdpH689606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:P62495	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-750990|intact:EBI-1047744|uniprotkb:B2R6B4|uniprotkb:D3DQC1|uniprotkb:P46055|uniprotkb:Q5M7Z7|uniprotkb:Q96CG1|ensembl:ENSP00000353741	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:erf1_human(display_long)|uniprotkb:ETF1(gene name)|psi-mi:ETF1(display_short)|uniprotkb:ERF1(gene name synonym)|uniprotkb:Protein Cl1(gene name synonym)|uniprotkb:RF1(gene name synonym)|uniprotkb:SUP45L1(gene name synonym)|uniprotkb:TB3-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004721.1|refseq:NP_001243231.1|refseq:NP_001278903.1|refseq:NP_001278904.1|refseq:XP_005271978.1|ensembl:ENSG00000120705(gene)|ensembl:ENST00000360541(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006415"(translational termination)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0008079"(translation termination factor activity)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0018444"(translation release factor complex)|go:"GO:0043022"(ribosome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR024049|interpro:IPR029064|interpro:IPR042226|mint:P62495|rcsb pdb:1DT9|rcsb pdb:2HST|rcsb pdb:2KTU|rcsb pdb:2KTV|rcsb pdb:2LGT|rcsb pdb:2LLX|rcsb pdb:2MQ6|rcsb pdb:2MQ9|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3JAG|rcsb pdb:3JAH|rcsb pdb:3JAI|rcsb pdb:4D5N|rcsb pdb:4D61|rcsb pdb:5A8L|rcsb pdb:5LZT|rcsb pdb:5LZU|rcsb pdb:5LZV|rcsb pdb:6D90|rcsb pdb:6IP8|rcsb pdb:6XA1|rcsb pdb:6ZME|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:vUI2Eq2wx++5VxZ2MK1EQ0jnWMI9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:P61011	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2854176|uniprotkb:B2R759|uniprotkb:P13624|uniprotkb:B4DUW6|ensembl:ENSP00000216774|ensembl:ENSP00000451818|ensembl:ENSP00000504518|ensembl:ENSP00000504673	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:srp54_human(display_long)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:XP_011535408.1|refseq:NP_001139754.1|refseq:NP_003127.1|ensembl:ENSG00000100883(gene)|ensembl:ENST00000678963(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019003"(GDP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|mint:P61011|rcsb pdb:1MFQ|rcsb pdb:1QB2|rcsb pdb:5L3Q|rcsb pdb:6Y2Z|rcsb pdb:6Y30|rcsb pdb:6Y31|rcsb pdb:6Y32|rcsb pdb:7NFX|ensembl:ENST00000216774(transcript)|reactome:R-HSA-1799339|ensembl:ENST00000556994(transcript)|ensembl:ENST00000677647(transcript)	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:8iRlU+NvhLEJNv7B90TAZyRqwiY9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q8TCS8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1052020|uniprotkb:Q53SU0|uniprotkb:Q68CN1|uniprotkb:Q7Z7D1|uniprotkb:Q8IWX1|uniprotkb:Q96T05|uniprotkb:Q9BRU3|uniprotkb:Q9BVX0|ensembl:ENSP00000393953|ensembl:ENSP00000400646	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:pnpt1_human(display_long)|uniprotkb:Polynucleotide phosphorylase 1(gene name synonym)|uniprotkb:Polynucleotide phosphorylase-like protein(gene name synonym)|uniprotkb:PNPase old-35(gene name synonym)|uniprotkb:3'-5' RNA exonuclease OLD35(gene name synonym)|uniprotkb:PNPT1(gene name)|psi-mi:PNPT1(display_short)|uniprotkb:PNPASE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_149100.2|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0097222"(mitochondrial mRNA polyadenylation)|go:"GO:0097421"(liver regeneration)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR003029(S1, RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR020568|interpro:IPR022967|interpro:IPR027408|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|rcsb pdb:3U1K|rcsb pdb:5ZF6|ensembl:ENSG00000138035(gene)|ensembl:ENST00000415374(transcript)|ensembl:ENST00000447944(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000957"(mitochondrial RNA catabolic process)|go:"GO:0000958"(mitochondrial mRNA catabolic process)|go:"GO:0000962"(positive regulation of mitochondrial RNA catabolic process)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0000965"(mitochondrial RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0034046"("poly(G) binding")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035927"(RNA import into mitochondrion)|go:"GO:0035928"(rRNA import into mitochondrion)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0045025"(mitochondrial degradosome)|go:"GO:0004654"(polyribonucleotide nucleotidyltransferase activity)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060416"(response to growth hormone)|dip:DIP-50226N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:W9hr1vfWv1b0v4xfMYatfKfOMcg9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q8NC56	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-6149955|uniprotkb:Q5T972|uniprotkb:Q5T974|uniprotkb:B4DVH5|uniprotkb:E7EVT2|ensembl:ENSP00000293760|ensembl:ENSP00000478539	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:lemd2_human(display_long)|uniprotkb:LEMD2(gene name)|psi-mi:LEMD2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001335638.1|refseq:NP_851853.1|refseq:NP_001137416.1|ensembl:ENSG00000161904(gene)|ensembl:ENST00000293760(transcript)|ensembl:ENST00000614475(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022008"(neurogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060914"(heart formation)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR018996|interpro:IPR034994|interpro:IPR041885|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9668328	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:mDTKCvVjxMtw3uYpitoTXSZHAYY9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q96CX2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-358358|ensembl:ENSP00000366694	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q9UQ88	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-373024|uniprotkb:O95227|uniprotkb:O95228|uniprotkb:O96012|uniprotkb:Q12821|uniprotkb:Q12853|uniprotkb:Q12854|uniprotkb:Q5QPR0|uniprotkb:Q5QPR1|uniprotkb:Q5QPR2|uniprotkb:Q9UBC4|uniprotkb:Q9UBI3|uniprotkb:Q9UEI1|uniprotkb:Q9UEI2|uniprotkb:Q9UP53|uniprotkb:Q9UP54|uniprotkb:Q9UP55|uniprotkb:Q9UP56|uniprotkb:Q9UQ86|uniprotkb:Q9UQ87|uniprotkb:Q9UQ89|uniprotkb:Q2TAJ0|ensembl:ENSP00000367900	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:cd11a_human(display_long)|uniprotkb:CDK11A(gene name)|psi-mi:CDK11A(display_short)|uniprotkb:PITSLREB(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 2(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:CDC2L2(gene name synonym)|uniprotkb:CDC2L3(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L2(gene name synonym)|uniprotkb:Cell division protein kinase 11A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_076916.2|refseq:NP_277071.2|refseq:NP_001300825.1|refseq:NP_001300911.1|ensembl:ENSG00000008128(gene)|ensembl:ENST00000378633(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:Q9UQ88|reactome:R-HSA-380270	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:h30ee1oqCuzFkWhpX9dsmJFl9Y09606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q96RF0	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-298169|uniprotkb:Q05BB3|uniprotkb:Q0VG02|ensembl:ENSP00000342276|uniprotkb:B4E2B3|uniprotkb:H7BXX3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:snx18_human(display_long)|uniprotkb:SNX18(gene name)|psi-mi:SNX18(display_short)|uniprotkb:SH3 and PX domain-containing protein 3B(gene name synonym)|uniprotkb:SH3PXD3B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001096045.1|refseq:NP_001138899.1|refseq:NP_443102.2|ensembl:ENSG00000178996(gene)|go:"GO:0006897"(endocytosis)|ensembl:ENST00000343017(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028646|interpro:IPR035557|interpro:IPR035703|interpro:IPR036028|interpro:IPR036871|mint:Q96RF0|reactome:R-HSA-8856828	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:HpHLfTZ0EfhC6oMHeSr1GCgZaI49606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q00688	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1044081|uniprotkb:Q14317|ensembl:ENSP00000216330|ensembl:ENSP00000379374|uniprotkb:B2R4Q9	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:fkbp3_human(display_long)|uniprotkb:FKBP3(gene name)|psi-mi:FKBP3(display_short)|uniprotkb:FKBP25(gene name synonym)|uniprotkb:FK506-binding protein 3(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP25(gene name synonym)|uniprotkb:Rapamycin-selective 25 kDa immunophilin(gene name synonym)|uniprotkb:25 kDa FK506-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_002004.1|ensembl:ENSG00000100442(gene)|ensembl:ENST00000216330(transcript)|ensembl:ENST00000396062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR041200|interpro:IPR043368|mint:Q00688|rcsb pdb:1PBK|rcsb pdb:2KFV|rcsb pdb:2MPH|rcsb pdb:5D75|rcsb pdb:5GPG|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xU5FDlTZzy8veAtOaoLtQMeBsr09606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q16527	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2959737|ensembl:ENSP00000310901|ensembl:ENSP00000450056|uniprotkb:Q93030	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:csrp2_human(display_long)|uniprotkb:CSRP2(gene name)|psi-mi:CSRP2(display_short)|uniprotkb:LMO5(gene name synonym)|uniprotkb:SMLIM(gene name synonym)|uniprotkb:Cysteine-rich protein 2(gene name synonym)|uniprotkb:LIM domain only protein 5(gene name synonym)|uniprotkb:Smooth muscle cell LIM protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001312.1|ensembl:ENSG00000175183(gene)|ensembl:ENST00000311083(transcript)|ensembl:ENST00000546966(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0060537"(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001287894.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:nyQ01E4UJb21IE/mZhZjXakJoyo9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q0VF96	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-3388952|intact:EBI-28971578|ensembl:ENSP00000281282|uniprotkb:Q9C0B4|uniprotkb:Q7Z2L3|uniprotkb:Q695C7|uniprotkb:Q52LR0|uniprotkb:Q96JV2|uniprotkb:Q05BZ4|uniprotkb:Q96MN6	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:cgnl1_human(display_long)|uniprotkb:CGNL1(gene name)|psi-mi:CGNL1(display_short)|uniprotkb:JACOP(gene name synonym)|uniprotkb:KIAA1749(gene name synonym)|uniprotkb:Junction-associated coiled-coil protein(gene name synonym)|uniprotkb:Paracingulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSP00000281282|ensembl:ENSG00000128849(gene)|ensembl:ENST00000281282(transcript)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0016459"(myosin complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR002928(Myosin tail)|refseq:NP_116255.2|refseq:XP_016878175.1|refseq:NP_001239264.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:9YBGN8pBNQZm3tvMb2w0NdXLV0U9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q9H2D6	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-715619|uniprotkb:B1AHD4|uniprotkb:B1AHD7|uniprotkb:O94797|uniprotkb:Q2PZW8|uniprotkb:Q2Q3Z9|uniprotkb:Q2Q400|uniprotkb:Q5R3M6|uniprotkb:Q96DW1|uniprotkb:Q9BT77|uniprotkb:Q9BTL7|uniprotkb:Q9BY98|uniprotkb:Q9Y3L4|ensembl:ENSP00000496394|intact:EBI-2560917|uniprotkb:F2Z2W0|uniprotkb:F8W6V6	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:tara_human(display_long)|uniprotkb:Protein Tara(gene name synonym)|uniprotkb:Trio-associated repeat on actin(gene name synonym)|uniprotkb:TRIOBP(gene name)|psi-mi:TRIOBP(display_short)|uniprotkb:KIAA1662(gene name synonym)|uniprotkb:TARA(gene name synonym)|uniprotkb:HRIHFB2122(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001034230.1|refseq:NP_008963.3|refseq:NP_619538.2|ensembl:ENSG00000100106(gene)|ensembl:ENST00000644935(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030047"(actin modification)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045159"(myosin II binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051301"(cell division)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q9H2D6|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:2evioSQxAnH1x5VPGsZyK+fJTY09606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q01082	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q13813	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q9P0K7	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1023749|uniprotkb:Q6V1W9|uniprotkb:Q7Z5I4|uniprotkb:Q7Z733|uniprotkb:Q9P2L2|uniprotkb:Q9Y3T5|uniprotkb:E9PED3|intact:EBI-2555698|ensembl:ENSP00000265109|ensembl:ENSP00000388725|ensembl:ENSP00000422942	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:rai14_human(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001138992.1|refseq:NP_001138993.1|refseq:NP_001138994.1|refseq:NP_001138995.1|refseq:NP_001138997.1|refseq:NP_056392.2|refseq:XP_011512319.1|refseq:XP_011512320.1|refseq:XP_011512321.1|refseq:XP_011512322.1|refseq:XP_011512323.1|refseq:XP_011512324.1|ensembl:ENSG00000039560(gene)|ensembl:ENST00000265109(transcript)|ensembl:ENST00000428746(transcript)|ensembl:ENST00000503673(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9P0K7|refseq:XP_006714532.1|refseq:XP_016864824.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:m5hQYx6HEi9QEAey1UiNpeAp6tw9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q6NYC8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2557469|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|uniprotkb:A2AB01|uniprotkb:Q6ZTV1|ensembl:ENSP00000274853|ensembl:ENSP00000373067|ensembl:ENSP00000382150|ensembl:ENSP00000383400|ensembl:ENSP00000388790|ensembl:ENSP00000400129|ensembl:ENSP00000400990|ensembl:ENSP00000404066|ensembl:ENSP00000405234|ensembl:ENSP00000412456|ensembl:ENSP00000413596|ensembl:ENSP00000416648|ensembl:ENSP00000480270	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112(gene)|ensembl:ENSG00000206485(gene)|ensembl:ENSG00000225060(gene)|ensembl:ENSG00000229998(gene)|ensembl:ENST00000274853(transcript)|ensembl:ENST00000383573(transcript)|ensembl:ENST00000399199(transcript)|ensembl:ENST00000400554(transcript)|ensembl:ENST00000437121(transcript)|ensembl:ENST00000438815(transcript)|ensembl:ENST00000438945(transcript)|ensembl:ENSG00000230341(gene)|ensembl:ENST00000443517(transcript)|ensembl:ENSG00000234000(gene)|ensembl:ENST00000444206(transcript)|ensembl:ENST00000449705(transcript)|ensembl:ENST00000451544(transcript)|ensembl:ENST00000455935(transcript)|ensembl:ENST00000615527(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q9UPN3	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-522925|uniprotkb:E9PJT0|uniprotkb:O75053|uniprotkb:Q5VW20|uniprotkb:Q8WXY2|uniprotkb:Q9H540|uniprotkb:Q9UKP0|uniprotkb:Q9ULG9|intact:EBI-28967632|uniprotkb:B1ALC5|uniprotkb:Q8WXY1|uniprotkb:Q96PK2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:macf1_human(display_long)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENST00000361689|ensembl:ENSP00000354573|ensembl:ENSG00000127603|refseq:NP_036222.3|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Z6G|rcsb pdb:5VE9|rcsb pdb:5X57|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0042060"(wound healing)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|dip:DIP-50616N|mint:Q9UPN3	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:G5PesqPZZxQhwDgW0pBJSkJNcZ49606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:O75369	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q14247	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:O15085	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-311099|intact:EBI-28988539|ensembl:ENSP00000354644|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_055599.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_937879.1|ensembl:ENSP00000354644|ensembl:ENST00000368194|ensembl:ENSP00000357177|dip:DIP-31622N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q9UEY8	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2838698|uniprotkb:Q9UEY7|uniprotkb:O43243|uniprotkb:Q92773|uniprotkb:Q5VU09|uniprotkb:D3DRA8|intact:EBI-28975834|ensembl:ENSP00000348381	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:addg_human(display_long)|uniprotkb:ADD3(gene name)|psi-mi:ADD3(display_short)|uniprotkb:ADDL(gene name synonym)|uniprotkb:Adducin-like protein 70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENST00000277900|ensembl:ENSP00000277900|ensembl:ENSP00000348381|ensembl:ENST00000360162|ensembl:ENSP00000353286|refseq:NP_001307520.1|refseq:NP_001307521.1|refseq:NP_001307522.1|refseq:NP_001307523.1|refseq:NP_001112.2|refseq:NP_058432.1|refseq:NP_063968.1|interpro:IPR036409|mint:Q9UEY8|reactome:R-HSA-5223345|reactome:R-HSA-9013405|reactome:R-HSA-9035034|ensembl:ENSG00000148700(gene)|ensembl:ENST00000356080(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR027772	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:10ZAHAI90VaVf/xUxFcNVX5cIts9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q07157	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q8WXH0	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-2372294|uniprotkb:Q540G1|uniprotkb:Q8N1S3|uniprotkb:Q8NF49|uniprotkb:Q8TER7|uniprotkb:Q8WWW3|uniprotkb:Q8WWW4|uniprotkb:Q8WWW5|uniprotkb:Q8WXH1|uniprotkb:Q9NU50|uniprotkb:Q9UFQ4|uniprotkb:Q9Y2L4|uniprotkb:Q9Y4R1|uniprotkb:Q86YP9|uniprotkb:B4DND7|uniprotkb:B4DPR6|uniprotkb:I6XXQ5|ensembl:ENSP00000341781	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:syne2_human(display_long)|uniprotkb:SYNE2(gene name)|psi-mi:SYNE2(display_short)|uniprotkb:KIAA1011(gene name synonym)|uniprotkb:NUA(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSP00000344528|ensembl:ENSP00000341781|ensembl:ENST00000358025|ensembl:ENSP00000350719|ensembl:ENST00000458046|ensembl:ENSP00000391937|ensembl:ENST00000555002|ensembl:ENSP00000450831|ensembl:ENST00000341472|refseq:NP_055995.4|refseq:NP_878914.1|refseq:NP_878917.1|refseq:NP_878918.2|dip:DIP-53409N|ensembl:ENSG00000054654(gene)|ensembl:ENST00000344113(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005925"(focal adhesion)|go:"GO:0007097"(nuclear migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR030266|interpro:IPR036872|rcsb pdb:4DXS|rcsb pdb:4FI9|rcsb pdb:6XF1|reactome:R-HSA-1221632	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:wLHWOXR+dUHkcs93g+F2av/9wm49606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q96FS4	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1054981|uniprotkb:O14518|uniprotkb:O60484|uniprotkb:O60618|uniprotkb:Q2YD83|ensembl:ENSP00000377771|ensembl:ENSP00000436269	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:sipa1_human(display_long)|uniprotkb:GTPase-activating protein Spa-1(gene name synonym)|uniprotkb:p130 SPA-1(gene name synonym)|uniprotkb:SIPA1(gene name)|psi-mi:SIPA1(display_short)|uniprotkb:SPA1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_006738.3|refseq:NP_694985.29|refseq:XP_011543516.1|refseq:XP_005274246.1|ensembl:ENSP00000377771|ensembl:ENSP00000436269|ensembl:ENST00000394224(transcript)|ensembl:ENST00000534313(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|ensembl:ENSG00000213445(gene)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042631"(cellular response to water deprivation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035974|interpro:IPR036034|mint:Q96FS4|reactome:R-HSA-392517	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:N5g/PMrgPEjYn5Cqv5uo0cAMPJI9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q92614	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-949059|ensembl:ENSP00000437073|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|uniprotkb:Q5QD01	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	dip:DIP-46631N|ensembl:ENSG00000196535(gene)|ensembl:ENST00000527372(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016477"(cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|go:"GO:1903028"(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR031244|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q6WCQ1	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1022605|uniprotkb:Q3KQZ5|uniprotkb:Q5FB94|uniprotkb:Q6DHW2|uniprotkb:Q7Z5Y2|uniprotkb:Q8N390|uniprotkb:Q96G40|ensembl:ENSP00000342379	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mprip_human(display_long)|uniprotkb:MRIP(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym)|uniprotkb:MPRIP(gene name)|psi-mi:MPRIP(display_short)|uniprotkb:KIAA0864(gene name synonym)|uniprotkb:RHOIP3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000133030(gene)|ensembl:ENST00000341712(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q6WCQ1|reactome:R-HSA-6802952|refseq:NP_055949.2|refseq:NP_958431.2	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:QoGbbg2ehuQogDM1Dlxzw6xj59s9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q05682	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:Q9Y2D5	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1754555|uniprotkb:Q9UG26|uniprotkb:B1ALX9|uniprotkb:B2RTU4|uniprotkb:B3KQ00|uniprotkb:B4DTZ2|uniprotkb:B7ZW07|uniprotkb:B9EJB5	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:akap2_human(display_long)|uniprotkb:AKAP2(gene name)|psi-mi:AKAP2(display_short)|uniprotkb:KIAA0920(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP-KL(gene name synonym)|uniprotkb:PRKA2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100330|imex:IM-25792-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001004065.2|refseq:NP_001130034.1|refseq:NP_001185585.1|refseq:NP_009134.1|refseq:NP_671492.1|interpro:IPR029304	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:xfHb6tD0ToXJPHpl4MlbKczjzSg9606	rigid:hOHvwfDgHvW7nUGeZUq8vQjCESw	false	mutation:362-362,387-387,306-306,192-192,234-234,267-267,115-115,165-165,179-179,249-249,287-287,327-327,372-372,410-410,128-128	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P56945	uniprotkb:O15078	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100813|imex:IM-25792-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606	rigid:SXLsPKABPtnT3ueZNZaCs3MC8Og	false	mutation:128-128,165-165,249-249,234-234,115-115,179-179,267-267,287-287,327-327,362-362,306-306,372-372,410-410,387-387,192-192	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07858	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000503300|ensembl:ENSP00000503435|ensembl:ENSP00000503487|ensembl:ENSP00000503513|ensembl:ENSP00000503578|ensembl:ENSP00000503608|ensembl:ENSP00000503652|ensembl:ENSP00000503674|ensembl:ENSP00000503858|ensembl:ENSP00000503909|ensembl:ENSP00000504161|ensembl:ENSP00000504226|ensembl:ENSP00000504336|ensembl:ENSP00000504480|ensembl:ENSP00000504638|ensembl:ENSP00000504659|ensembl:ENSP00000504797|ensembl:ENSP00000503280|ensembl:ENSP00000342070|ensembl:ENSP00000345672|ensembl:ENSP00000431143|ensembl:ENSP00000431518|ensembl:ENSP00000432077|ensembl:ENSP00000432244|ensembl:ENSP00000432408|ensembl:ENSP00000433215|ensembl:ENSP00000433379|ensembl:ENSP00000433929|ensembl:ENSP00000434217|ensembl:ENSP00000434725|ensembl:ENSP00000435074|ensembl:ENSP00000435105|ensembl:ENSP00000435260|ensembl:ENSP00000435886|ensembl:ENSP00000473301|ensembl:ENSP00000502963|ensembl:ENSP00000503006|ensembl:ENSP00000503052|ensembl:ENSP00000503078|ensembl:ENSP00000503174	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100813|imex:IM-25792-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|ensembl:ENST00000345125(transcript)|ensembl:ENST00000353047(transcript)|ensembl:ENST00000524654(transcript)|ensembl:ENST00000526481(transcript)|ensembl:ENST00000526645(transcript)|ensembl:ENST00000527215(transcript)|ensembl:ENST00000534382(transcript)|ensembl:ENST00000527243(transcript)|ensembl:ENST00000534510(transcript)|ensembl:ENST00000676691(transcript)|ensembl:ENST00000676755(transcript)|ensembl:ENST00000676825(transcript)|ensembl:ENST00000676843(transcript)|ensembl:ENST00000676952(transcript)|ensembl:ENST00000677082(transcript)|ensembl:ENST00000677366(transcript)|ensembl:ENST00000677415(transcript)|ensembl:ENST00000528965(transcript)|ensembl:ENST00000530296(transcript)|ensembl:ENST00000530640(transcript)|ensembl:ENST00000677418(transcript)|ensembl:ENST00000677544(transcript)|ensembl:ENST00000677650(transcript)|ensembl:ENST00000677671(transcript)|ensembl:ENST00000677819(transcript)|ensembl:ENST00000677873(transcript)|ensembl:ENST00000678092(transcript)|ensembl:ENST00000678145(transcript)|ensembl:ENST00000678242(transcript)|ensembl:ENST00000531089(transcript)|ensembl:ENST00000678357(transcript)|ensembl:ENST00000531502(transcript)|ensembl:ENST00000678615(transcript)|ensembl:ENST00000532392(transcript)|ensembl:ENST00000678929(transcript)|ensembl:ENST00000532656(transcript)|ensembl:ENST00000533455(transcript)|ensembl:ENST00000679051(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042981"(regulation of apoptotic process)|ensembl:ENST00000679128(transcript)|go:"GO:0043394"(proteoglycan binding)|ensembl:ENST00000679140(transcript)|go:"GO:0046697"(decidualization)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|ensembl:ENSG00000164733(gene)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1CSB|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:XP_006716307.1|refseq:XP_006716308.1|dip:DIP-42785N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	rigid:SXLsPKABPtnT3ueZNZaCs3MC8Og	false	mutation:128-128,165-165,249-249,234-234,115-115,179-179,267-267,287-287,327-327,362-362,306-306,372-372,410-410,387-387,192-192	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P56945	uniprotkb:P07814	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15100813|imex:IM-25792-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N	-	-	-	figure legend:supplementary table 6|stimulant:interactome post VEGEF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606	rigid:SXLsPKABPtnT3ueZNZaCs3MC8Og	false	mutation:128-128,165-165,249-249,234-234,115-115,179-179,267-267,287-287,327-327,362-362,306-306,372-372,410-410,387-387,192-192	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P46940	uniprotkb:P56945	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15187036|imex:IM-25792-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	-	-	-	figure legend:figure 4 b and c|agonist:VEGF|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rigid:JgcgrK9daPcP6YYQpvE/FkmlpmM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46940	uniprotkb:P63000	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15187134|imex:IM-25792-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N	-	-	-	figure legend:figure 7C|stimulant:post VEGF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	rigid:usUVZvnUkeRX3hFHKNT8hgfi1Ww	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P56945	uniprotkb:P07737	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15187156|imex:IM-25792-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N	-	-	-	figure legend:figure supplementary 3|agonist:VEGF|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606	rigid:PQ5ZM/1p+hIbn90yKIJR1HwetIY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P56945	uniprotkb:Q9Y5S2	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-1043430|uniprotkb:Q2L7A5|uniprotkb:Q86TJ1|uniprotkb:Q9ULU5|ensembl:ENSP00000355237|uniprotkb:A9JR72	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:mrckb_human(display_long)|uniprotkb:CDC42-binding protein kinase beta(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase beta(gene name synonym)|uniprotkb:DMPK-like beta(gene name synonym)|uniprotkb:CDC42BPB(gene name)|psi-mi:CDC42BPB(display_short)|uniprotkb:KIAA1124(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15187156|imex:IM-25792-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000198752(gene)|ensembl:ENST00000361246(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR031597|interpro:IPR033232|interpro:IPR042718|rcsb pdb:3QFV|rcsb pdb:3TKU|rcsb pdb:4UAK|rcsb pdb:4UAL|rcsb pdb:5OTE|rcsb pdb:5OTF|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|refseq:NP_006026.3	-	-	-	figure legend:figure supplementary 3|agonist:VEGF|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:FaheT9htZ/NtYfTKvNDcLqNtQiQ9606	rigid:PQ5ZM/1p+hIbn90yKIJR1HwetIY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P56945	uniprotkb:P46940	intact:EBI-702093|uniprotkb:B4DIW5|uniprotkb:F8WA69|uniprotkb:Q6QEF7|uniprotkb:B7Z7X7|uniprotkb:F5GXV6|uniprotkb:B3KWD7|uniprotkb:B4DEV4|uniprotkb:B4DGB5|uniprotkb:E9PCL5|uniprotkb:E9PCV2|uniprotkb:F5GXA2|uniprotkb:F5H7Z0|intact:EBI-10963425|ensembl:ENSP00000162330	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	psi-mi:bcar1_human(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:BCAR1(gene name)|psi-mi:BCAR1(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:CRKAS(gene name synonym)|uniprotkb:CASS1(gene name synonym)|uniprotkb:Cas scaffolding protein family member 1(gene name synonym)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:"MI:0096"(pull down)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15187069|imex:IM-25792-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164185.1|refseq:NP_001164186.1|refseq:NP_001164187.1|refseq:NP_001164188.1|refseq:NP_001164189.1|refseq:NP_001164190.1|refseq:NP_001164191.1|refseq:NP_055382.2|refseq:XP_016879386.1|ensembl:ENSP00000162330|ensembl:ENST00000393420|ensembl:ENSP00000377072|ensembl:ENST00000393422|ensembl:ENSP00000377074|ensembl:ENST00000418647|ensembl:ENSP00000391669|ensembl:ENST00000420641|ensembl:ENSP00000392708|ensembl:ENST00000535626|ensembl:ENSP00000440370|ensembl:ENST00000538440|ensembl:ENSP00000443841|ensembl:ENST00000542031|ensembl:ENSP00000440415|dip:DIP-33855N|ensembl:ENSG00000050820(gene)|ensembl:ENST00000162330(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:P56945|rcsb pdb:1WYX|rcsb pdb:3T6G|rcsb pdb:5O2M|rcsb pdb:5O2P|rcsb pdb:5O2Q|reactome:R-HSA-186763|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	-	-	-	figure legend:Supp. Fig. 5|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2017/07/03	rogid:ssRxMtaHJrQ1lMJ02FpOh3xIaWY9606	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	rigid:JgcgrK9daPcP6YYQpvE/FkmlpmM	false	sufficient binding region:1-433	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46940	uniprotkb:P63000	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Evans et al. (2016)	pubmed:28007913|imex:IM-25792	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-15187118|imex:IM-25792-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N	-	-	-	figure legend:figure 7 c|stimulant:post VEGF stimulation|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2017/06/22	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	rigid:usUVZvnUkeRX3hFHKNT8hgfi1Ww	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)