#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61916	uniprotkb:Q7Z3B1	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13642909|imex:IM-25693-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	-	-	-	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/02	2017/02/22	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	-	sufficient binding region:40-215(IPR013783)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61916	uniprotkb:Q7Z3B1	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13642933|imex:IM-25693-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/02	2017/02/07	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	-	sufficient binding region:40-215(IPR013783)|sufficient binding region:139..145-313	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z3B1	uniprotkb:P61916	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13642972|imex:IM-25693-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	-	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/02/02	2017/02/07	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	green fluorescent protein tag:39-39	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7Z3B1	uniprotkb:P61916	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643043|imex:IM-25693-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	-	-	-	figure legend:1B-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/02/02	2017/02/08	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	flag tag:314-314	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P61916	uniprotkb:Q7Z3B1	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:"MI:0096"(pull down)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643061|imex:IM-25693-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	-	-	-	figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/02	2017/02/08	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	glutathione s tranferase tag:n-n	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P61916	uniprotkb:Q7Z3B1	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643092|imex:IM-25693-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	-	-	-	figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/02/02	2017/02/08	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P61916	uniprotkb:Q7Z3B1	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:"MI:0096"(pull down)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643100|imex:IM-25693-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	-	-	-	figure legend:1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/02/02	2017/02/08	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	flag tag:?-?	sufficient binding region:139..145-315..315|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P61916	uniprotkb:Q7Z3B1	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643126|imex:IM-25693-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-crt-mg)|taxid:9606(human GBM/Astrocytoma cell line)	-	2017/02/02	2017/02/08	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P61916	uniprotkb:Q7Z3B1	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112	intact:EBI-4314838|uniprotkb:Q5VT21|uniprotkb:Q6UY06|uniprotkb:Q8NAQ3|uniprotkb:Q8N440|ensembl:ENSP00000350364	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	psi-mi:negr1_human(display_long)|uniprotkb:NEGR1(gene name)|psi-mi:NEGR1(display_short)|uniprotkb:IGLON4(gene name synonym)|uniprotkb:IgLON family member 4(gene name synonym)|uniprotkb:UNQ2433/PRO4993(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Kim et al. (2017)	imex:IM-25693|pubmed:27940359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643160|imex:IM-25693-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038	refseq:NP_776169.2|ensembl:ENSG00000172260(gene)|ensembl:ENST00000357731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLD|rcsb pdb:6U6T|reactome:R-HSA-163125	go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u178)|taxid:9606(human-Astrocytoma cell line)	-	2017/02/02	2017/02/08	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	rogid:7aOTGGmWmxCluRrwEyosmc2h/Bo9606	rigid:ABJFHD6YesoF/59Q0Ug04Lemy0A	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)