#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q53W63 uniprotkb:Q5SKW1 intact:EBI-16208148|ensemblbacteria:BAD71895 intact:EBI-2106988|ensemblbacteria:BAD70355 psi-mi:ldrp_thet8(display_long)|uniprotkb:Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein LdrP(gene name synonym)|uniprotkb:Light induced transcription regulator-dependent regulatory protein(gene name synonym)|uniprotkb:LitR-dependent regulatory protein(gene name synonym)|uniprotkb:TTHB099(locus name) psi-mi:q5skw1_thet8(display_long)|uniprotkb:sigA(gene name)|psi-mi:sigA(display_short)|uniprotkb:TTHA0532(locus name) psi-mi:"MI:0114"(x-ray crystallography) Feng et al. (2016) pubmed:27284196|doi:10.1126/science.aaf4417|imex:IM-25457 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16208170|imex:IM-25457-1|dip:DIP-201164E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAD71895(gene)|ensemblbacteria:BAD71895(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR012318(Helix-turn-helix motif, Crp-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3B02|rcsb pdb:5I2D|refseq:WP_011229195.1|refseq:YP_145338.1|dip:DIP-62042N refseq:YP_143798.1|refseq:WP_011228005.1|dip:DIP-47010N|ensemblbacteria:BAD70355(gene)|ensemblbacteria:BAD70355(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016987"(sigma factor activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|rcsb pdb:1IW7|rcsb pdb:1SMY|rcsb pdb:1ZYR|rcsb pdb:2A68|rcsb pdb:2A69|rcsb pdb:2A6E|rcsb pdb:2A6H|rcsb pdb:2BE5|rcsb pdb:2CW0|rcsb pdb:3DXJ|rcsb pdb:3EQL|rcsb pdb:3WOD|rcsb pdb:4G7H|rcsb pdb:4G7O|rcsb pdb:4G7Z|rcsb pdb:4MQ9|rcsb pdb:4OIN|rcsb pdb:4OIO|rcsb pdb:4OIP|rcsb pdb:4OIQ|rcsb pdb:4OIR|rcsb pdb:4Q4Z|rcsb pdb:4Q5S|rcsb pdb:5D4C|rcsb pdb:5D4D|rcsb pdb:5D4E|rcsb pdb:5E17|rcsb pdb:5E18|rcsb pdb:5I2D|rcsb pdb:5TMC|rcsb pdb:5TMF|rcsb pdb:5VO8|rcsb pdb:5VOI|rcsb pdb:5XJ0|rcsb pdb:6KQD|rcsb pdb:6KQE|rcsb pdb:6KQF|rcsb pdb:6KQG|rcsb pdb:6KQH|rcsb pdb:6KQL|rcsb pdb:6KQM|rcsb pdb:6KQN|rcsb pdb:6L74|rcsb pdb:6LTS|rcsb pdb:6OVR|rcsb pdb:6WOX|rcsb pdb:6WOY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nHHYcfq/yPeNQYO3REf7sAvOOVQ300852 rogid:Mo11jPlSCt3c34JN+7P2oY027i0300852 rigid:5HVhwAwYrx/loLLR4f2WlI9GUvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53W63 uniprotkb:Q5SHR6 intact:EBI-16208148|ensemblbacteria:BAD71895 intact:EBI-2106870|ensemblbacteria:BAD71487 psi-mi:ldrp_thet8(display_long)|uniprotkb:Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein LdrP(gene name synonym)|uniprotkb:Light induced transcription regulator-dependent regulatory protein(gene name synonym)|uniprotkb:LitR-dependent regulatory protein(gene name synonym)|uniprotkb:TTHB099(locus name) psi-mi:rpoa_thet8(display_long)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:TTHA1664(locus name)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short) psi-mi:"MI:0114"(x-ray crystallography) Feng et al. (2016) pubmed:27284196|doi:10.1126/science.aaf4417|imex:IM-25457 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16208170|imex:IM-25457-1|dip:DIP-201164E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAD71895(gene)|ensemblbacteria:BAD71895(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR012318(Helix-turn-helix motif, Crp-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3B02|rcsb pdb:5I2D|refseq:WP_011229195.1|refseq:YP_145338.1|dip:DIP-62042N refseq:YP_144930.1|refseq:WP_011173698.1|dip:DIP-47009N|ensemblbacteria:BAD71487(gene)|ensemblbacteria:BAD71487(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:1ZYR|rcsb pdb:2A68|rcsb pdb:2A69|rcsb pdb:2A6E|rcsb pdb:2A6H|rcsb pdb:2BE5|rcsb pdb:2CW0|rcsb pdb:2O5I|rcsb pdb:2O5J|rcsb pdb:3AOH|rcsb pdb:3AOI|rcsb pdb:3DXJ|rcsb pdb:3WOD|rcsb pdb:4G7H|rcsb pdb:4G7O|rcsb pdb:4G7Z|rcsb pdb:4GZY|rcsb pdb:4GZZ|rcsb pdb:4MQ9|rcsb pdb:4OIN|rcsb pdb:4OIO|rcsb pdb:4OIP|rcsb pdb:4OIQ|rcsb pdb:4OIR|rcsb pdb:4WQS|rcsb pdb:4WQT|rcsb pdb:5D4C|rcsb pdb:5D4D|rcsb pdb:5D4E|rcsb pdb:5E17|rcsb pdb:5E18|rcsb pdb:5I2D|rcsb pdb:5TMC|rcsb pdb:5TMF|rcsb pdb:5VO8|rcsb pdb:5X21|rcsb pdb:5X22|rcsb pdb:5XJ0|rcsb pdb:6ASG|rcsb pdb:6KQD|rcsb pdb:6KQE|rcsb pdb:6KQF|rcsb pdb:6KQG|rcsb pdb:6KQH|rcsb pdb:6KQL|rcsb pdb:6KQM|rcsb pdb:6KQN|rcsb pdb:6L74|rcsb pdb:6LTS|rcsb pdb:6M6A|rcsb pdb:6M6B|rcsb pdb:6M6C|rcsb pdb:6OVR|rcsb pdb:6OVY|rcsb pdb:6OW3|rcsb pdb:6OY6|rcsb pdb:6OY7|rcsb pdb:6P70|rcsb pdb:6P71|rcsb pdb:6WOX|rcsb pdb:6WOY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nHHYcfq/yPeNQYO3REf7sAvOOVQ300852 rogid:A8LQMbyYxVQjtLtFDwESQYGueZ8300852 rigid:5HVhwAwYrx/loLLR4f2WlI9GUvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53W63 uniprotkb:Q8RQE9 intact:EBI-16208148|ensemblbacteria:BAD71895 intact:EBI-2106897|uniprotkb:Q5SHB7|ensemblbacteria:BAD71636 psi-mi:ldrp_thet8(display_long)|uniprotkb:Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein LdrP(gene name synonym)|uniprotkb:Light induced transcription regulator-dependent regulatory protein(gene name synonym)|uniprotkb:LitR-dependent regulatory protein(gene name synonym)|uniprotkb:TTHB099(locus name) psi-mi:rpob_thet8(display_long)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:TTHA1813(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short) psi-mi:"MI:0114"(x-ray crystallography) Feng et al. (2016) pubmed:27284196|doi:10.1126/science.aaf4417|imex:IM-25457 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16208170|imex:IM-25457-1|dip:DIP-201164E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAD71895(gene)|ensemblbacteria:BAD71895(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR012318(Helix-turn-helix motif, Crp-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3B02|rcsb pdb:5I2D|refseq:WP_011229195.1|refseq:YP_145338.1|dip:DIP-62042N refseq:YP_145079.1|refseq:WP_011228935.1|dip:DIP-47011N|ensemblbacteria:BAD71636(gene)|ensemblbacteria:BAD71636(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR019462|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107|rcsb pdb:1IW7|rcsb pdb:1SMY|rcsb pdb:1ZYR|rcsb pdb:2A68|rcsb pdb:2A69|rcsb pdb:2A6E|rcsb pdb:2A6H|rcsb pdb:2BE5|rcsb pdb:2CW0|rcsb pdb:2O5I|rcsb pdb:2O5J|rcsb pdb:2PPB|rcsb pdb:3AOH|rcsb pdb:3AOI|rcsb pdb:3DXJ|rcsb pdb:3EQL|rcsb pdb:3WOD|rcsb pdb:3WOE|rcsb pdb:3WOF|rcsb pdb:4G7H|rcsb pdb:4G7O|rcsb pdb:4G7Z|rcsb pdb:4GZY|rcsb pdb:4GZZ|rcsb pdb:4MQ9|rcsb pdb:4OIN|rcsb pdb:4OIO|rcsb pdb:4OIP|rcsb pdb:4OIQ|rcsb pdb:4OIR|rcsb pdb:4Q4Z|rcsb pdb:4Q5S|rcsb pdb:4WQS|rcsb pdb:4WQT|rcsb pdb:5D4C|rcsb pdb:5D4D|rcsb pdb:5D4E|rcsb pdb:5E17|rcsb pdb:5E18|rcsb pdb:5I2D|rcsb pdb:5TMC|rcsb pdb:5TMF|rcsb pdb:5VO8|rcsb pdb:5VOI|rcsb pdb:5X21|rcsb pdb:5X22|rcsb pdb:5XJ0|rcsb pdb:6ASG|rcsb pdb:6KQD|rcsb pdb:6KQE|rcsb pdb:6KQF|rcsb pdb:6KQH|rcsb pdb:6KQL|rcsb pdb:6KQM|rcsb pdb:6KQN|rcsb pdb:6L74|rcsb pdb:6LTS|rcsb pdb:6M6A|rcsb pdb:6M6B|rcsb pdb:6M6C|rcsb pdb:6OVR|rcsb pdb:6OVY|rcsb pdb:6OW3|rcsb pdb:6OY5|rcsb pdb:6OY6|rcsb pdb:6OY7|rcsb pdb:6P70|rcsb pdb:6P71|rcsb pdb:6WOX|rcsb pdb:6WOY|rcsb pdb:6KQG psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nHHYcfq/yPeNQYO3REf7sAvOOVQ300852 rogid:U03u3vgmDfae6t/s+swi6onzou8300852 rigid:5HVhwAwYrx/loLLR4f2WlI9GUvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53W63 uniprotkb:Q8RQE8 intact:EBI-16208148|ensemblbacteria:BAD71895 intact:EBI-2106930|uniprotkb:Q5SHB8|ensemblbacteria:BAD71635 psi-mi:ldrp_thet8(display_long)|uniprotkb:Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein LdrP(gene name synonym)|uniprotkb:Light induced transcription regulator-dependent regulatory protein(gene name synonym)|uniprotkb:LitR-dependent regulatory protein(gene name synonym)|uniprotkb:TTHB099(locus name) psi-mi:rpoc_thet8(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:TTHA1812(locus name) psi-mi:"MI:0114"(x-ray crystallography) Feng et al. (2016) pubmed:27284196|doi:10.1126/science.aaf4417|imex:IM-25457 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16208170|imex:IM-25457-1|dip:DIP-201164E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAD71895(gene)|ensemblbacteria:BAD71895(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR012318(Helix-turn-helix motif, Crp-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3B02|rcsb pdb:5I2D|refseq:WP_011229195.1|refseq:YP_145338.1|dip:DIP-62042N refseq:YP_145078.1|refseq:WP_011228934.1|dip:DIP-47007N|ensemblbacteria:BAD71635(gene)|ensemblbacteria:BAD71635(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:1IW7|rcsb pdb:1SMY|rcsb pdb:1ZYR|rcsb pdb:2A68|rcsb pdb:2A69|rcsb pdb:2A6E|rcsb pdb:2A6H|rcsb pdb:2BE5|rcsb pdb:2CW0|rcsb pdb:2O5I|rcsb pdb:2O5J|rcsb pdb:2PPB|rcsb pdb:3AOH|rcsb pdb:3AOI|rcsb pdb:3DXJ|rcsb pdb:3EQL|rcsb pdb:3WOD|rcsb pdb:4G7H|rcsb pdb:4G7O|rcsb pdb:4G7Z|rcsb pdb:4GZY|rcsb pdb:4GZZ|rcsb pdb:4MQ9|rcsb pdb:4OIN|rcsb pdb:4OIO|rcsb pdb:4OIP|rcsb pdb:4OIQ|rcsb pdb:4OIR|rcsb pdb:4Q4Z|rcsb pdb:4Q5S|rcsb pdb:4WQS|rcsb pdb:4WQT|rcsb pdb:5D4C|rcsb pdb:5D4D|rcsb pdb:5D4E|rcsb pdb:5E17|rcsb pdb:5E18|rcsb pdb:5I2D|rcsb pdb:5TMC|rcsb pdb:5TMF|rcsb pdb:5VO8|rcsb pdb:5VOI|rcsb pdb:5X21|rcsb pdb:5X22|rcsb pdb:5XJ0|rcsb pdb:6ASG|rcsb pdb:6KQD|rcsb pdb:6KQE|rcsb pdb:6KQF|rcsb pdb:6KQG|rcsb pdb:6KQH|rcsb pdb:6KQL|rcsb pdb:6KQM|rcsb pdb:6KQN|rcsb pdb:6L74|rcsb pdb:6LTS|rcsb pdb:6M6A|rcsb pdb:6M6B|rcsb pdb:6M6C|rcsb pdb:6OVR|rcsb pdb:6OVY|rcsb pdb:6OW3|rcsb pdb:6OY5|rcsb pdb:6OY6|rcsb pdb:6OY7|rcsb pdb:6P70|rcsb pdb:6P71|rcsb pdb:6WOX|rcsb pdb:6WOY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nHHYcfq/yPeNQYO3REf7sAvOOVQ300852 rogid:Ae2eggjy4Xbrz0JNjIuN8YOUbXw300852 rigid:5HVhwAwYrx/loLLR4f2WlI9GUvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53W63 uniprotkb:Q8RQE7 intact:EBI-16208148|ensemblbacteria:BAD71895 intact:EBI-2106962|uniprotkb:Q5SI19|ensemblbacteria:BAD71384 psi-mi:ldrp_thet8(display_long)|uniprotkb:Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein LdrP(gene name synonym)|uniprotkb:Light induced transcription regulator-dependent regulatory protein(gene name synonym)|uniprotkb:LitR-dependent regulatory protein(gene name synonym)|uniprotkb:TTHB099(locus name) psi-mi:rpoz_thet8(display_long)|uniprotkb:rpoZ(gene name)|psi-mi:rpoZ(display_short)|uniprotkb:Transcriptase subunit omega(gene name synonym)|uniprotkb:RNA polymerase omega subunit(gene name synonym)|uniprotkb:TTHA1561(locus name) psi-mi:"MI:0114"(x-ray crystallography) Feng et al. (2016) pubmed:27284196|doi:10.1126/science.aaf4417|imex:IM-25457 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16208170|imex:IM-25457-1|dip:DIP-201164E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAD71895(gene)|ensemblbacteria:BAD71895(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR012318(Helix-turn-helix motif, Crp-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3B02|rcsb pdb:5I2D|refseq:WP_011229195.1|refseq:YP_145338.1|dip:DIP-62042N refseq:YP_144827.1|refseq:WP_008633185.1|dip:DIP-47008N|ensemblbacteria:BAD71384(gene)|ensemblbacteria:BAD71384(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR003716(RNA polymerase, omega subunit)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR036161|rcsb pdb:1IW7|rcsb pdb:1SMY|rcsb pdb:1ZYR|rcsb pdb:2A68|rcsb pdb:2A69|rcsb pdb:2A6E|rcsb pdb:2A6H|rcsb pdb:2BE5|rcsb pdb:2CW0|rcsb pdb:2O5I|rcsb pdb:2O5J|rcsb pdb:2PPB|rcsb pdb:3AOH|rcsb pdb:3AOI|rcsb pdb:3DXJ|rcsb pdb:3EQL|rcsb pdb:3WOD|rcsb pdb:4G7H|rcsb pdb:4G7O|rcsb pdb:4G7Z|rcsb pdb:4GZY|rcsb pdb:4GZZ|rcsb pdb:4MQ9|rcsb pdb:4OIN|rcsb pdb:4OIO|rcsb pdb:4OIP|rcsb pdb:4OIQ|rcsb pdb:4OIR|rcsb pdb:4Q4Z|rcsb pdb:4Q5S|rcsb pdb:4WQS|rcsb pdb:4WQT|rcsb pdb:5D4C|rcsb pdb:5D4D|rcsb pdb:5D4E|rcsb pdb:5E17|rcsb pdb:5E18|rcsb pdb:5I2D|rcsb pdb:5TMC|rcsb pdb:5TMF|rcsb pdb:5VO8|rcsb pdb:5VOI|rcsb pdb:5XJ0|rcsb pdb:6ASG|rcsb pdb:6KQD|rcsb pdb:6KQE|rcsb pdb:6KQF|rcsb pdb:6KQG|rcsb pdb:6KQH|rcsb pdb:6KQL|rcsb pdb:6KQM|rcsb pdb:6KQN|rcsb pdb:6L74|rcsb pdb:6LTS|rcsb pdb:6M6A|rcsb pdb:6M6B|rcsb pdb:6M6C|rcsb pdb:6OVR|rcsb pdb:6OVY|rcsb pdb:6OW3|rcsb pdb:6OY6|rcsb pdb:6OY7|rcsb pdb:6P70|rcsb pdb:6P71|rcsb pdb:6WOX|rcsb pdb:6WOY|go:"GO:0003677"(DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nHHYcfq/yPeNQYO3REf7sAvOOVQ300852 rogid:FBcwRdcnN6yZp/AvwWciRwuGej0300852 rigid:5HVhwAwYrx/loLLR4f2WlI9GUvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53W63 uniprotkb:Q5SHR6 intact:EBI-16208148|ensemblbacteria:BAD71895 intact:EBI-2106870|ensemblbacteria:BAD71487 psi-mi:ldrp_thet8(display_long)|uniprotkb:Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein LdrP(gene name synonym)|uniprotkb:Light induced transcription regulator-dependent regulatory protein(gene name synonym)|uniprotkb:LitR-dependent regulatory protein(gene name synonym)|uniprotkb:TTHB099(locus name) psi-mi:rpoa_thet8(display_long)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:TTHA1664(locus name)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Feng et al. (2016) pubmed:27284196|doi:10.1126/science.aaf4417|imex:IM-25457 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16208191|imex:IM-25457-2|dip:DIP-201165E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAD71895(gene)|ensemblbacteria:BAD71895(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR012318(Helix-turn-helix motif, Crp-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3B02|rcsb pdb:5I2D|refseq:WP_011229195.1|refseq:YP_145338.1|dip:DIP-62042N refseq:YP_144930.1|refseq:WP_011173698.1|dip:DIP-47009N|ensemblbacteria:BAD71487(gene)|ensemblbacteria:BAD71487(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:1ZYR|rcsb pdb:2A68|rcsb pdb:2A69|rcsb pdb:2A6E|rcsb pdb:2A6H|rcsb pdb:2BE5|rcsb pdb:2CW0|rcsb pdb:2O5I|rcsb pdb:2O5J|rcsb pdb:3AOH|rcsb pdb:3AOI|rcsb pdb:3DXJ|rcsb pdb:3WOD|rcsb pdb:4G7H|rcsb pdb:4G7O|rcsb pdb:4G7Z|rcsb pdb:4GZY|rcsb pdb:4GZZ|rcsb pdb:4MQ9|rcsb pdb:4OIN|rcsb pdb:4OIO|rcsb pdb:4OIP|rcsb pdb:4OIQ|rcsb pdb:4OIR|rcsb pdb:4WQS|rcsb pdb:4WQT|rcsb pdb:5D4C|rcsb pdb:5D4D|rcsb pdb:5D4E|rcsb pdb:5E17|rcsb pdb:5E18|rcsb pdb:5I2D|rcsb pdb:5TMC|rcsb pdb:5TMF|rcsb pdb:5VO8|rcsb pdb:5X21|rcsb pdb:5X22|rcsb pdb:5XJ0|rcsb pdb:6ASG|rcsb pdb:6KQD|rcsb pdb:6KQE|rcsb pdb:6KQF|rcsb pdb:6KQG|rcsb pdb:6KQH|rcsb pdb:6KQL|rcsb pdb:6KQM|rcsb pdb:6KQN|rcsb pdb:6L74|rcsb pdb:6LTS|rcsb pdb:6M6A|rcsb pdb:6M6B|rcsb pdb:6M6C|rcsb pdb:6OVR|rcsb pdb:6OVY|rcsb pdb:6OW3|rcsb pdb:6OY6|rcsb pdb:6OY7|rcsb pdb:6P70|rcsb pdb:6P71|rcsb pdb:6WOX|rcsb pdb:6WOY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nHHYcfq/yPeNQYO3REf7sAvOOVQ300852 rogid:A8LQMbyYxVQjtLtFDwESQYGueZ8300852 rigid:wlMgpegfUlkIRBq1/6PZuy9VGPU false mutation disrupting interaction strength:125-125|mutation disrupting interaction strength:185-185 sufficient binding region:253-310|fluorescein label:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)