#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O43439 uniprotkb:Q9GZV8 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16207970|imex:IM-25448-1|dip:DIP-201150E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rigid:PXrCNAHlZPt1CXP32ClIpVRzdHE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43439 uniprotkb:Q3V6T2 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-2266839|uniprotkb:A1IGE7|uniprotkb:Q53SF1|uniprotkb:Q581G3|uniprotkb:Q5HYD0|uniprotkb:Q7Z339|uniprotkb:Q7Z3C5|uniprotkb:B7ZM78|uniprotkb:C9JG83|ensembl:ENSP00000410608|ensembl:ENSP00000495919 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:grdn_human(display_long)|uniprotkb:CCDC88A(gene name)|psi-mi:CCDC88A(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:GRDN(gene name synonym)|uniprotkb:KIAA1212(gene name synonym)|uniprotkb:Girders of actin filament(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 88A(gene name synonym)|uniprotkb:Akt phosphorylation enhancer(gene name synonym)|uniprotkb:Hook-related protein 1(gene name synonym)|uniprotkb:G alpha-interacting vesicle-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:XP_011531267.1|refseq:XP_011531268.1|refseq:XP_011531269.1|refseq:NP_001129069.1|refseq:NP_060554.3|refseq:NP_001241872.1|dip:DIP-50784N|ensembl:ENSG00000115355(gene)|ensembl:ENST00000436346(transcript)|ensembl:ENST00000642200(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030142"(COPI-coated Golgi to ER transport vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0061024"(membrane organization)|go:"GO:1903566"(positive regulation of protein localization to cilium)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR027717|interpro:IPR036872|interpro:IPR043936|rcsb pdb:6MHF|reactome:R-HSA-9696264|reactome:R-HSA-9696273|go:"GO:0072660"(maintenance of protein location in plasma membrane) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:6kUpfRsRH31AqsM5d3q6mybkgdw9606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:P40763 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N psi-mi:"MI:0465"(dip) - crc64:6C00632211C8012D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:P78527 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:Q9UNF1 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-725832|uniprotkb:O76058|uniprotkb:Q5BJF3|uniprotkb:Q8NAL6|uniprotkb:Q9H218|uniprotkb:Q9P0U9|uniprotkb:A6NMX0|uniprotkb:Q9UM52|ensembl:ENSP00000218439|ensembl:ENSP00000364193|ensembl:ENSP00000364198|ensembl:ENSP00000364209|ensembl:ENSP00000379526 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:magd2_human(display_long)|uniprotkb:MAGE-D2 antigen(gene name synonym)|uniprotkb:Breast cancer-associated gene 1 protein(gene name synonym)|uniprotkb:11B6(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated protein JCL-1(gene name synonym)|uniprotkb:MAGED2(gene name)|psi-mi:MAGED2(display_short)|uniprotkb:BCG1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:NP_055414.2|refseq:NP_803182.1|refseq:NP_957516.1|ensembl:ENSG00000102316(gene)|ensembl:ENST00000218439(transcript)|ensembl:ENST00000375053(transcript)|ensembl:ENST00000375058(transcript)|ensembl:ENST00000375068(transcript)|ensembl:ENST00000396224(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0016020"(membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0070294"(renal sodium ion absorption)|interpro:IPR002190(MAGE protein)|interpro:IPR028810|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9UNF1|reactome:R-HSA-114608|dip:DIP-50722N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:fXavezmKy58aGuVgzvDYjwNw3B89606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:Q8N163 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:Q8N680 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-2515601|ensembl:ENSP00000323183|uniprotkb:A8K7C7|uniprotkb:Q9P245|uniprotkb:Q5SZ81 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:zbtb2_human(display_long)|uniprotkb:ZBTB2(gene name)|psi-mi:ZBTB2(display_short)|uniprotkb:KIAA1483(gene name synonym)|uniprotkb:ZNF437(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N ensembl:ENSG00000181472(gene)|ensembl:ENST00000325144(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR011333(BTB/POZ fold)|refseq:XP_011534306.1|refseq:NP_065912.1|refseq:XP_005267133.1|dip:DIP-53681N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:J8GO/U3lUReim2GO9Xq7D3dRZBQ9606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:Q9P2R3 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:237ungtRc80jqTOKBUnFX9qDUGw9606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:O75081 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-1190217|uniprotkb:O60615|uniprotkb:O60616|uniprotkb:O60617|uniprotkb:O75082|uniprotkb:O75107|uniprotkb:O75108|uniprotkb:Q6P5W6|uniprotkb:Q0P5Z6|uniprotkb:D3DX78|intact:EBI-28983666|ensembl:ENSP00000268679 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:mtg16_human(display_long)|uniprotkb:MTG16(gene name synonym)|uniprotkb:MTGR2(gene name synonym)|uniprotkb:ZMYND4(gene name synonym)|uniprotkb:Myeloid translocation gene on chromosome 16 protein(gene name synonym)|uniprotkb:MTG8-related protein 2(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 4(gene name synonym)|uniprotkb:CBFA2T3(gene name)|psi-mi:CBFA2T3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:NP_005178.4|refseq:NP_787127.1|ensembl:ENSP00000268679|ensembl:ENST00000327483|ensembl:ENSP00000332122|dip:DIP-48898N|ensembl:ENSG00000129993(gene)|ensembl:ENST00000268679(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013292("Myeloid transforming gene on chromosome 16 (MTG16)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:O75081 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:YMP60LeA62hg4mNz15o70E/PqwE9606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:Q99496 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:Q9GZV8 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16207987|imex:IM-25448-2|dip:DIP-201152E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rigid:u3lzHhk2vAtrFU4T7h6rB05v4i4 false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O43439 uniprotkb:Q9GZV8 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16208089|imex:IM-25448-5|dip:DIP-201150E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rigid:PXrCNAHlZPt1CXP32ClIpVRzdHE false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O70374 uniprotkb:E9Q3T6 intact:EBI-8006755|intact:MINT-2568187|uniprotkb:Q6P288|uniprotkb:Q30BK8|uniprotkb:B2RRH8|ensembl:ENSMUSP00000043087 intact:EBI-16208032|ensembl:ENSMUSP00000044245|uniprotkb:Q3URU1 psi-mi:mtg8r_mouse(display_long)|uniprotkb:Cbfa2t2(gene name)|psi-mi:Cbfa2t2(display_short)|uniprotkb:Cbfa2t2h(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:Mtgr1(gene name synonym) psi-mi:prd14_mouse(display_long)|uniprotkb:Prdm14(gene name)|psi-mi:Prdm14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16208072|imex:IM-25448-4|dip:DIP-201153E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766448.1|refseq:NP_033953.1|refseq:XP_006498703.1|dip:DIP-62032N|ensembl:ENSMUSG00000038533(gene)|ensembl:ENSMUST00000045270(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:O70374|rcsb pdb:5ECJ ensembl:ENSMUSG00000042414(gene)|ensembl:ENSMUST00000047577(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|rcsb pdb:5ECJ|refseq:NP_001074678.2|dip:DIP-62031N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:CA4xMx/HKHH6tJ0ktwQaJfzaBUU10090 rogid:DJyLEvVwxvjsus2bAUnEASq7KZs10090 rigid:vEVx84rm2NqiepBH6WmZk7UctiM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43439 uniprotkb:Q9GZV8 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16208015|imex:IM-25448-3|dip:DIP-201150E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rigid:PXrCNAHlZPt1CXP32ClIpVRzdHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZV8 uniprotkb:Q3V6T2 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-2266839|uniprotkb:A1IGE7|uniprotkb:Q53SF1|uniprotkb:Q581G3|uniprotkb:Q5HYD0|uniprotkb:Q7Z339|uniprotkb:Q7Z3C5|uniprotkb:B7ZM78|uniprotkb:C9JG83|ensembl:ENSP00000410608|ensembl:ENSP00000495919 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:grdn_human(display_long)|uniprotkb:CCDC88A(gene name)|psi-mi:CCDC88A(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:GRDN(gene name synonym)|uniprotkb:KIAA1212(gene name synonym)|uniprotkb:Girders of actin filament(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 88A(gene name synonym)|uniprotkb:Akt phosphorylation enhancer(gene name synonym)|uniprotkb:Hook-related protein 1(gene name synonym)|uniprotkb:G alpha-interacting vesicle-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16208108|imex:IM-25448-6|dip:DIP-201151E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N refseq:XP_011531267.1|refseq:XP_011531268.1|refseq:XP_011531269.1|refseq:NP_001129069.1|refseq:NP_060554.3|refseq:NP_001241872.1|dip:DIP-50784N|ensembl:ENSG00000115355(gene)|ensembl:ENST00000436346(transcript)|ensembl:ENST00000642200(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030142"(COPI-coated Golgi to ER transport vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0061024"(membrane organization)|go:"GO:1903566"(positive regulation of protein localization to cilium)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR027717|interpro:IPR036872|interpro:IPR043936|rcsb pdb:6MHF|reactome:R-HSA-9696264|reactome:R-HSA-9696273|go:"GO:0072660"(maintenance of protein location in plasma membrane) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:6kUpfRsRH31AqsM5d3q6mybkgdw9606 rigid:izA0WLICcY+0EIV9xEV1Uf7SFQw false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9GZV8 uniprotkb:Q8N680 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-2515601|ensembl:ENSP00000323183|uniprotkb:A8K7C7|uniprotkb:Q9P245|uniprotkb:Q5SZ81 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:zbtb2_human(display_long)|uniprotkb:ZBTB2(gene name)|psi-mi:ZBTB2(display_short)|uniprotkb:KIAA1483(gene name synonym)|uniprotkb:ZNF437(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16208108|imex:IM-25448-6|dip:DIP-201151E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N ensembl:ENSG00000181472(gene)|ensembl:ENST00000325144(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR011333(BTB/POZ fold)|refseq:XP_011534306.1|refseq:NP_065912.1|refseq:XP_005267133.1|dip:DIP-53681N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:J8GO/U3lUReim2GO9Xq7D3dRZBQ9606 rigid:izA0WLICcY+0EIV9xEV1Uf7SFQw false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9GZV8 uniprotkb:Q9P2R3 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16208108|imex:IM-25448-6|dip:DIP-201151E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:237ungtRc80jqTOKBUnFX9qDUGw9606 rigid:izA0WLICcY+0EIV9xEV1Uf7SFQw false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9GZV8 uniprotkb:P61244 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16208108|imex:IM-25448-6|dip:DIP-201151E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rigid:izA0WLICcY+0EIV9xEV1Uf7SFQw false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9GZV8 uniprotkb:O75081 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-1190217|uniprotkb:O60615|uniprotkb:O60616|uniprotkb:O60617|uniprotkb:O75082|uniprotkb:O75107|uniprotkb:O75108|uniprotkb:Q6P5W6|uniprotkb:Q0P5Z6|uniprotkb:D3DX78|intact:EBI-28983666|ensembl:ENSP00000268679 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:mtg16_human(display_long)|uniprotkb:MTG16(gene name synonym)|uniprotkb:MTGR2(gene name synonym)|uniprotkb:ZMYND4(gene name synonym)|uniprotkb:Myeloid translocation gene on chromosome 16 protein(gene name synonym)|uniprotkb:MTG8-related protein 2(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 4(gene name synonym)|uniprotkb:CBFA2T3(gene name)|psi-mi:CBFA2T3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16208108|imex:IM-25448-6|dip:DIP-201151E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N refseq:NP_005178.4|refseq:NP_787127.1|ensembl:ENSP00000268679|ensembl:ENST00000327483|ensembl:ENSP00000332122|dip:DIP-48898N|ensembl:ENSG00000129993(gene)|ensembl:ENST00000268679(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013292("Myeloid transforming gene on chromosome 16 (MTG16)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:O75081 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:YMP60LeA62hg4mNz15o70E/PqwE9606 rigid:izA0WLICcY+0EIV9xEV1Uf7SFQw false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9GZV8 uniprotkb:Q99496 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16208108|imex:IM-25448-6|dip:DIP-201151E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:izA0WLICcY+0EIV9xEV1Uf7SFQw false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q9GZV8 uniprotkb:O43439 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tu et al. (2016) pubmed:27281218|doi:10.1038/nature18004|imex:IM-25448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16208108|imex:IM-25448-6|dip:DIP-201151E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rigid:izA0WLICcY+0EIV9xEV1Uf7SFQw false flag tag:n-n - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)