#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9HCE5 uniprotkb:Q86U44-1 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-16084936|ensembl:ENSP00000298717 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:q86u44-1(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Wang et al. (2016) pubmed:27281194|doi:10.1038/nature18298|imex:IM-25449 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16207786|imex:IM-25449-1|dip:DIP-196056E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|intact:EBI-11105430(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rigid:uC9+mYi7Kaiy3nHOIXKZhXiq7zA false sufficient binding region:109-408 sufficient binding region:369-580 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HCE5 uniprotkb:Q86U44-1 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-16084936|ensembl:ENSP00000298717 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:q86u44-1(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Wang et al. (2016) pubmed:27281194|doi:10.1038/nature18298|imex:IM-25449 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16207807|imex:IM-25449-2|dip:DIP-196056E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|intact:EBI-11105430(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rigid:uC9+mYi7Kaiy3nHOIXKZhXiq7zA false sufficient binding region:109-408 sufficient binding region:369-580 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HCE5 uniprotkb:Q86U44-1 intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2 intact:EBI-16084936|ensembl:ENSP00000298717 psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym) psi-mi:q86u44-1(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Wang et al. (2016) pubmed:27281194|doi:10.1038/nature18298|imex:IM-25449 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16207828|imex:IM-25449-3|dip:DIP-196056E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|intact:EBI-11105430(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606 rogid:B7ORoNVaQb6/OA77jPsn558+k409606 rigid:uC9+mYi7Kaiy3nHOIXKZhXiq7zA false sufficient binding region:109-408 sufficient binding region:369-580 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)