#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q64HS0 uniprotkb:I3LK71 intact:EBI-16367252 intact:EBI-16367291|ensembl:ENSSSCP00000024485 psi-mi:q64hs0_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:i3lk71_pig(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Thulasi et al. (2015) pubmed:27199973|imex:IM-26135 taxid:292591("A/swine/Saskatchewan/18789/02(H1N1)")|taxid:292591(Influenza A virus) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-16367279|imex:IM-26135-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSSSCG00000038947(gene)|ensembl:ENSSSCT00000023644(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045120"(pronucleus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|reactome:R-SSC-72163|reactome:R-SSC-9013422 - - - figure legend:6A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2017/08/08 2017/12/04 rogid:OjLe0nwcA4AKBiZz9sCU0gkYIWY292591 rogid:JHMxjMd5qf4yLtc8cM4/X5H/Bd49823 rigid:IuRqrUW6EINXv1WqlggvckTDoA4 false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64HS0 uniprotkb:K7GP99 intact:EBI-16367252 intact:EBI-16367372|ensembl:ENSSSCP00000029712 psi-mi:q64hs0_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:k7gp99_pig(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short) psi-mi:"MI:0096"(pull down) Thulasi et al. (2015) pubmed:27199973|imex:IM-26135 taxid:292591("A/swine/Saskatchewan/18789/02(H1N1)")|taxid:292591(Influenza A virus) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-16427759|imex:IM-26135-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSSSCG00000013638(gene)|ensembl:ENSSSCT00000033206(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519 - - - figure legend:6C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2017/08/08 2017/12/04 rogid:OjLe0nwcA4AKBiZz9sCU0gkYIWY292591 rogid:PyYPPi+yAWei2Yyk7+u5o0/HkLE9823 rigid:G36j1FUOHtwVadhxdWBXvxIhe24 false - his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64HS0 uniprotkb:I3LQS0 intact:EBI-16367252 intact:EBI-16367314|ensembl:ENSSSCP00000026450 psi-mi:q64hs0_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:i3lqs0_pig(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short) psi-mi:"MI:0096"(pull down) Thulasi et al. (2015) pubmed:27199973|imex:IM-26135 taxid:292591("A/swine/Saskatchewan/18789/02(H1N1)")|taxid:292591(Influenza A virus) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-16427738|imex:IM-26135-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSSSCG00000022760(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|ensembl:ENSSSCT00000025854(transcript)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|reactome:R-SSC-72163|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome) - - - figure legend:6B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2017/08/08 2020/01/08 rogid:OjLe0nwcA4AKBiZz9sCU0gkYIWY292591 rogid:sKFVcfJNS9A47QNmPHqNZUc3GQU9823 rigid:SJcpTrSDdgpHhPJFLTrzJ3fIgyg false - his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64HS0 uniprotkb:F1S8L9 intact:EBI-16367252 intact:EBI-16367354|ensembl:ENSSSCP00000011596 psi-mi:q64hs0_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:f1s8l9_pig(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short) psi-mi:"MI:0096"(pull down) Thulasi et al. (2015) pubmed:27199973|imex:IM-26135 taxid:292591("A/swine/Saskatchewan/18789/02(H1N1)")|taxid:292591(Influenza A virus) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-16427752|imex:IM-26135-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSSSCG00000010877(gene)|ensembl:ENSSSCT00000011900(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136 - - - figure legend:6C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2017/08/08 2017/12/04 rogid:OjLe0nwcA4AKBiZz9sCU0gkYIWY292591 rogid:tWHFJyNNGq9kInCu5nhIn+T/wFM9823 rigid:zqaEEz5xcTR/DI4/mqGDlEAPUZg false - his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64HS0 uniprotkb:M3TYC8 intact:EBI-16367252 intact:EBI-16367407 psi-mi:q64hs0_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:m3tyc8_pig(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Thulasi et al. (2015) pubmed:27199973|imex:IM-26135 taxid:292591("A/swine/Saskatchewan/18789/02(H1N1)")|taxid:292591(Influenza A virus) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-16427766|imex:IM-26135-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR004208("Influenza B non-structural protein (NS1)") go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0051607"(defense response to virus)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR043136 - - - figure legend:6B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2017/08/08 2017/10/17 rogid:OjLe0nwcA4AKBiZz9sCU0gkYIWY292591 rogid:lezlTG47TwhFCX454HgpHkaZi8U9823 rigid:nrx/8owMP52Tz35IFe8VFMoSiXU false - his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)