#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G5EEG7 uniprotkb:G5EEG7 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:"MI:0071"(molecular sieving) Ulrich et al. (2016) pubmed:27150041|doi:10.1016/j.str.2016.03.016|imex:IM-25335 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16206188|imex:IM-25335-2|dip:DIP-200878E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rigid:LsIK/ybM05W169rMyJBbPTIwUpY false sufficient binding region:1-181|mutation decreasing interaction strength:15-15|mutation disrupting interaction strength:15-15|mutation disrupting interaction strength:18-18|mutation disrupting interaction strength:18-18 sufficient binding region:1-181|mutation decreasing interaction strength:15-15|mutation disrupting interaction strength:15-15|mutation disrupting interaction strength:18-18|mutation disrupting interaction strength:18-18 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG7 uniprotkb:G5EEG7 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:"MI:0114"(x-ray crystallography) Ulrich et al. (2016) pubmed:27150041|doi:10.1016/j.str.2016.03.016|imex:IM-25335 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16206170|imex:IM-25335-1|dip:DIP-200878E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rigid:LsIK/ybM05W169rMyJBbPTIwUpY false sufficient binding region:1-181 sufficient binding region:1-181 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EEG7 uniprotkb:G5EEG7 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:"MI:0067"(light scattering) Ulrich et al. (2016) pubmed:27150041|doi:10.1016/j.str.2016.03.016|imex:IM-25335 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16206261|imex:IM-25335-5|dip:DIP-200878E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rigid:LsIK/ybM05W169rMyJBbPTIwUpY false sufficient binding region:1-181|mutation decreasing interaction strength:15-15|mutation disrupting interaction strength:15-15|mutation disrupting interaction strength:18-18|mutation disrupting interaction strength:18-18 sufficient binding region:1-181|mutation decreasing interaction strength:15-15|mutation disrupting interaction strength:15-15|mutation disrupting interaction strength:18-18|mutation disrupting interaction strength:18-18 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9N4U5 uniprotkb:G5EEG7 intact:EBI-2415311|ensemblmetazoa:Y49F6B.4.1 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 psi-mi:smu2_caeel(display_long)|uniprotkb:smu-2(gene name)|psi-mi:smu-2(display_short)|uniprotkb:RED homolog(gene name synonym)|uniprotkb:Suppressor of Mec and Unc defects 2(gene name synonym)|uniprotkb:Y49F6B.4(orf name) psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:"MI:0071"(molecular sieving) Ulrich et al. (2016) pubmed:27150041|doi:10.1016/j.str.2016.03.016|imex:IM-25335 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16206289|imex:IM-25335-6|dip:DIP-200879E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494559.1|wormbase:Y49F6B.4|dip:DIP-55152N|ensemblmetazoa:WBGene00004896(gene)|ensemblmetazoa:Y49F6B.4.1(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|interpro:IPR012492(RED-like, C-terminal)|interpro:IPR012916(RED-like, N-terminal)|interpro:IPR039896|rcsb pdb:5EN6|rcsb pdb:5EN7 uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:d2mC6yFtPBOwPPhZcGJ2V1xIR9w6239 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rigid:xnDeOzWPlXhZ/08dw3utKSMHBgU false sufficient binding region:163-223|mutation disrupting interaction strength:220-220|mutation disrupting interaction strength:212-212 sufficient binding region:1-181 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9N4U5 uniprotkb:G5EEG7 intact:EBI-2415311|ensemblmetazoa:Y49F6B.4.1 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 psi-mi:smu2_caeel(display_long)|uniprotkb:smu-2(gene name)|psi-mi:smu-2(display_short)|uniprotkb:RED homolog(gene name synonym)|uniprotkb:Suppressor of Mec and Unc defects 2(gene name synonym)|uniprotkb:Y49F6B.4(orf name) psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:"MI:0071"(molecular sieving) Ulrich et al. (2016) pubmed:27150041|doi:10.1016/j.str.2016.03.016|imex:IM-25335 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16206237|imex:IM-25335-4|dip:DIP-200879E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494559.1|wormbase:Y49F6B.4|dip:DIP-55152N|ensemblmetazoa:WBGene00004896(gene)|ensemblmetazoa:Y49F6B.4.1(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|interpro:IPR012492(RED-like, C-terminal)|interpro:IPR012916(RED-like, N-terminal)|interpro:IPR039896|rcsb pdb:5EN6|rcsb pdb:5EN7 uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:d2mC6yFtPBOwPPhZcGJ2V1xIR9w6239 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rigid:xnDeOzWPlXhZ/08dw3utKSMHBgU false sufficient binding region:163-223 sufficient binding region:1-181|mutation disrupting interaction strength:96-96 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9N4U5 uniprotkb:G5EEG7 intact:EBI-2415311|ensemblmetazoa:Y49F6B.4.1 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 psi-mi:smu2_caeel(display_long)|uniprotkb:smu-2(gene name)|psi-mi:smu-2(display_short)|uniprotkb:RED homolog(gene name synonym)|uniprotkb:Suppressor of Mec and Unc defects 2(gene name synonym)|uniprotkb:Y49F6B.4(orf name) psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:"MI:0107"(surface plasmon resonance) Ulrich et al. (2016) pubmed:27150041|doi:10.1016/j.str.2016.03.016|imex:IM-25335 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16206216|imex:IM-25335-3|dip:DIP-200879E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494559.1|wormbase:Y49F6B.4|dip:DIP-55152N|ensemblmetazoa:WBGene00004896(gene)|ensemblmetazoa:Y49F6B.4.1(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|interpro:IPR012492(RED-like, C-terminal)|interpro:IPR012916(RED-like, N-terminal)|interpro:IPR039896|rcsb pdb:5EN6|rcsb pdb:5EN7 uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:d2mC6yFtPBOwPPhZcGJ2V1xIR9w6239 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rigid:xnDeOzWPlXhZ/08dw3utKSMHBgU false sufficient binding region:163-223 sufficient binding region:1-181 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9N4U5 uniprotkb:G5EEG7 intact:EBI-2415311|ensemblmetazoa:Y49F6B.4.1 intact:EBI-2411547|ensemblmetazoa:CC4.3.1|ensemblmetazoa:CC4.3.2 psi-mi:smu2_caeel(display_long)|uniprotkb:smu-2(gene name)|psi-mi:smu-2(display_short)|uniprotkb:RED homolog(gene name synonym)|uniprotkb:Suppressor of Mec and Unc defects 2(gene name synonym)|uniprotkb:Y49F6B.4(orf name) psi-mi:smu1_caeel(display_long)|uniprotkb:smu-1(gene name)|psi-mi:smu-1(display_short)|uniprotkb:Suppressor of Mec and Unc defects 1(gene name synonym)|uniprotkb:CC4.3(orf name) psi-mi:"MI:0114"(x-ray crystallography) Ulrich et al. (2016) pubmed:27150041|doi:10.1016/j.str.2016.03.016|imex:IM-25335 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16206318|imex:IM-25335-7|dip:DIP-200879E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494559.1|wormbase:Y49F6B.4|dip:DIP-55152N|ensemblmetazoa:WBGene00004896(gene)|ensemblmetazoa:Y49F6B.4.1(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|interpro:IPR012492(RED-like, C-terminal)|interpro:IPR012916(RED-like, N-terminal)|interpro:IPR039896|rcsb pdb:5EN6|rcsb pdb:5EN7 uniprotkb:O62120(uniprot-removed-ac)|refseq:NP_493279.1|wormbase:CC4.3|dip:DIP-61923N|ensemblmetazoa:CC4.3.1(transcript)|ensemblmetazoa:CC4.3.2(transcript)|ensemblmetazoa:WBGene00004895(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5EN6|rcsb pdb:5EN7|rcsb pdb:5EN8 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:d2mC6yFtPBOwPPhZcGJ2V1xIR9w6239 rogid:VN7DI1QKZPua+v0qjvBlAesd4ss6239 rigid:xnDeOzWPlXhZ/08dw3utKSMHBgU false sufficient binding region:163-223 sufficient binding region:1-181 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)