#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P38232	uniprotkb:P06782	intact:EBI-14921|uniprotkb:D6VQ50|ensemblfungi:YBR050C	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:reg2_yeast(display_long)|uniprotkb:YBR0504(orf name)|uniprotkb:YBR050C(locus name)|uniprotkb:REG2(gene name)|psi-mi:REG2(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maziarz et al. (2016)	pubmed:27107116|imex:IM-26213	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16397973|imex:IM-26213-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000254|refseq:NP_009606.1|ensemblfungi:YBR050C(gene)|ensemblfungi:YBR050C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR013860(Protein of unknown function DUF1752, fungi)|dip:DIP-2377N	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	-	-	crc64:F5C63565C986C4E3	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/24	2017/08/26	rogid:jtPrMWAuEL0wZiEOQo4vX3J1UwQ559292	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rigid:zQOCeQMuzaCVuo3P35APhpFuX5k	false	ha tag:n-n	O-phospho-L-threonine:210-210|mutation disrupting interaction strength:210-210	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38232	uniprotkb:P06782	intact:EBI-14921|uniprotkb:D6VQ50|ensemblfungi:YBR050C	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:reg2_yeast(display_long)|uniprotkb:YBR0504(orf name)|uniprotkb:YBR050C(locus name)|uniprotkb:REG2(gene name)|psi-mi:REG2(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0018"(two hybrid)	Maziarz et al. (2016)	pubmed:27107116|imex:IM-26213	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16394171|imex:IM-26213-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000254|refseq:NP_009606.1|ensemblfungi:YBR050C(gene)|ensemblfungi:YBR050C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR013860(Protein of unknown function DUF1752, fungi)|dip:DIP-2377N	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	-	-	crc64:F5C63565C986C4E3	figure legend:Fig. 1A, 2A, 6F|comment:The interaction was stronger under glucose-limiting conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/24	2017/08/24	rogid:jtPrMWAuEL0wZiEOQo4vX3J1UwQ559292	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rigid:zQOCeQMuzaCVuo3P35APhpFuX5k	false	mutation with no effect:169-169,171-171	mutation decreasing interaction strength:84-84|mutation disrupting interaction strength:210-210	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38232	uniprotkb:P06782	intact:EBI-14921|uniprotkb:D6VQ50|ensemblfungi:YBR050C	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:reg2_yeast(display_long)|uniprotkb:YBR0504(orf name)|uniprotkb:YBR050C(locus name)|uniprotkb:REG2(gene name)|psi-mi:REG2(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0018"(two hybrid)	Maziarz et al. (2016)	pubmed:27107116|imex:IM-26213	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16394175|imex:IM-26213-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000254|refseq:NP_009606.1|ensemblfungi:YBR050C(gene)|ensemblfungi:YBR050C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR013860(Protein of unknown function DUF1752, fungi)|dip:DIP-2377N	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	-	-	crc64:F5C63565C986C4E3	figure legend:Fig. 1A|comment:The interaction was stronger under glucose-limiting conditions|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/24	2017/08/24	rogid:jtPrMWAuEL0wZiEOQo4vX3J1UwQ559292	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rigid:zQOCeQMuzaCVuo3P35APhpFuX5k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32598	uniprotkb:P38232	intact:EBI-13715|ensemblfungi:YER133W|uniprotkb:D3DM39	intact:EBI-14921|uniprotkb:D6VQ50|ensemblfungi:YBR050C	psi-mi:pp12_yeast(display_long)|uniprotkb:GLC7(gene name)|psi-mi:GLC7(display_short)|uniprotkb:CID1(gene name synonym)|uniprotkb:DIS2(gene name synonym)|uniprotkb:YER133W(locus name)	psi-mi:reg2_yeast(display_long)|uniprotkb:YBR0504(orf name)|uniprotkb:YBR050C(locus name)|uniprotkb:REG2(gene name)|psi-mi:REG2(display_short)	psi-mi:"MI:0018"(two hybrid)	Maziarz et al. (2016)	pubmed:27107116|imex:IM-26213	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16397985|imex:IM-26213-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER133W(gene)|ensemblfungi:YER133W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000776"(kinetochore)|go:"GO:0001400"(mating projection base)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006397"(mRNA processing)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007116"(regulation of cell budding)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0005816"(spindle pole body)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0031297"(replication fork processing)|go:"GO:0032153"(cell division site)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|sgd:S000000935|refseq:NP_011059.3|mint:P32598|dip:DIP-1336N	sgd:S000000254|refseq:NP_009606.1|ensemblfungi:YBR050C(gene)|ensemblfungi:YBR050C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR013860(Protein of unknown function DUF1752, fungi)|dip:DIP-2377N	-	crc64:71B20E3A4ED93235	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/24	2017/08/26	rogid:wXXOB38if1fxEN0yLxeYTCXsuyU559292	rogid:jtPrMWAuEL0wZiEOQo4vX3J1UwQ559292	rigid:wBgwdDBJvB0uI51XWa4jAxrwF0s	false	-	mutation disrupting interaction strength:169-169,171-171	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)