#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y2U5	uniprotkb:Q9H7B4-1	intact:EBI-357393|ensembl:ENSP00000343463|ensembl:ENSP00000387246|ensembl:ENSP00000507315|uniprotkb:Q53QL9|uniprotkb:Q53S75|uniprotkb:Q59GZ6|uniprotkb:Q8NC32|uniprotkb:Q9NYK3|uniprotkb:B9EG87	intact:EBI-16204880|ensembl:ENSP00000419184	psi-mi:m3k2_human(display_long)|uniprotkb:MAP3K2(gene name)|psi-mi:MAP3K2(display_short)|uniprotkb:MAPKKK2(gene name synonym)|uniprotkb:MEKK2(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase 2(gene name synonym)	psi-mi:q9h7b4-1(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)	psi-mi:"MI:0515"(methyltransferase assay)	Van et al. (2016)	pubmed:27066749|doi:10.1016/j.str.2016.03.010|imex:IM-25331	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16204889|imex:IM-25331-1|dip:DIP-200875E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169967(gene)|ensembl:ENST00000344908(transcript)|ensembl:ENST00000409947(transcript)|ensembl:ENST00000682094(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034879|mint:Q9Y2U5|rcsb pdb:2CU1|rcsb pdb:2NPT|rcsb pdb:5EX0|rcsb pdb:5HQ8|rcsb pdb:6LDV|rcsb pdb:6LDW|rcsb pdb:6LDX|rcsb pdb:6LDY|refseq:NP_006600.3|dip:DIP-39756N	ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|intact:EBI-347919(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:wMiWIM12kFj36pj5WsyECABms3A9606	rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606	rigid:2q40byAbHlvlKfcKjAJyfOMtcM4	false	sufficient binding region:249-273	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2U5	uniprotkb:Q9H7B4-1	intact:EBI-357393|ensembl:ENSP00000343463|ensembl:ENSP00000387246|ensembl:ENSP00000507315|uniprotkb:Q53QL9|uniprotkb:Q53S75|uniprotkb:Q59GZ6|uniprotkb:Q8NC32|uniprotkb:Q9NYK3|uniprotkb:B9EG87	intact:EBI-16204880|ensembl:ENSP00000419184	psi-mi:m3k2_human(display_long)|uniprotkb:MAP3K2(gene name)|psi-mi:MAP3K2(display_short)|uniprotkb:MAPKKK2(gene name synonym)|uniprotkb:MEKK2(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase 2(gene name synonym)	psi-mi:q9h7b4-1(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Van et al. (2016)	pubmed:27066749|doi:10.1016/j.str.2016.03.010|imex:IM-25331	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16204909|imex:IM-25331-2|dip:DIP-200875E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169967(gene)|ensembl:ENST00000344908(transcript)|ensembl:ENST00000409947(transcript)|ensembl:ENST00000682094(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034879|mint:Q9Y2U5|rcsb pdb:2CU1|rcsb pdb:2NPT|rcsb pdb:5EX0|rcsb pdb:5HQ8|rcsb pdb:6LDV|rcsb pdb:6LDW|rcsb pdb:6LDX|rcsb pdb:6LDY|refseq:NP_006600.3|dip:DIP-39756N	ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|intact:EBI-347919(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:wMiWIM12kFj36pj5WsyECABms3A9606	rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606	rigid:2q40byAbHlvlKfcKjAJyfOMtcM4	false	sufficient binding region:250-264	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2U5	uniprotkb:Q9H7B4-1	intact:EBI-357393|ensembl:ENSP00000343463|ensembl:ENSP00000387246|ensembl:ENSP00000507315|uniprotkb:Q53QL9|uniprotkb:Q53S75|uniprotkb:Q59GZ6|uniprotkb:Q8NC32|uniprotkb:Q9NYK3|uniprotkb:B9EG87	intact:EBI-16204880|ensembl:ENSP00000419184	psi-mi:m3k2_human(display_long)|uniprotkb:MAP3K2(gene name)|psi-mi:MAP3K2(display_short)|uniprotkb:MAPKKK2(gene name synonym)|uniprotkb:MEKK2(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase 2(gene name synonym)	psi-mi:q9h7b4-1(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)	psi-mi:"MI:0515"(methyltransferase assay)	Van et al. (2016)	pubmed:27066749|doi:10.1016/j.str.2016.03.010|imex:IM-25331	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16204931|imex:IM-25331-3|dip:DIP-200875E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169967(gene)|ensembl:ENST00000344908(transcript)|ensembl:ENST00000409947(transcript)|ensembl:ENST00000682094(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034879|mint:Q9Y2U5|rcsb pdb:2CU1|rcsb pdb:2NPT|rcsb pdb:5EX0|rcsb pdb:5HQ8|rcsb pdb:6LDV|rcsb pdb:6LDW|rcsb pdb:6LDX|rcsb pdb:6LDY|refseq:NP_006600.3|dip:DIP-39756N	ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|intact:EBI-347919(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:wMiWIM12kFj36pj5WsyECABms3A9606	rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606	rigid:2q40byAbHlvlKfcKjAJyfOMtcM4	false	monomethylated L-lysine:260-260|N6,N6-dimethyl-L-lysine:260-260|N6,N6,N6-trimethyl-L-lysine:260-260	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)