#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13263 intact:EBI-16203811 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 dip:DIP-61991N psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"h3(1027)"(display_short)|psi-mi:EBI-16203811(display_long) psi-mi:"MI:0096"(pull down) Tasselli et al. (2016) pubmed:27043296|doi:10.1038/nsmb.3202|imex:IM-25405 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16203815|imex:IM-25405-2|dip:DIP-201082E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rogid:1gpqfHjyhBjmYCpud7+VxgTG+8E-2 rigid:7r85WVyhfQENU9tXXts1CsON30Q false - N-acetylated L-lysine:9-9|biotin tag:0-0 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N6T7 uniprotkb:P49450 intact:EBI-712415|ensembl:ENSP00000337332|uniprotkb:O75291|uniprotkb:Q6IAF5|uniprotkb:Q6PK99|uniprotkb:Q8NCD2|uniprotkb:Q9BSI5|uniprotkb:Q9BWP3|uniprotkb:Q9NRC7|uniprotkb:Q9UQD1|uniprotkb:B2RCD0 intact:EBI-1751979|uniprotkb:D6W544|uniprotkb:Q53T74|uniprotkb:Q9BVW2|ensembl:ENSP00000336868 psi-mi:sir6_human(display_long)|uniprotkb:SIR2-like protein 6(gene name synonym)|uniprotkb:SIRT6(gene name)|psi-mi:SIRT6(display_short)|uniprotkb:SIR2L6(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 6(gene name synonym) psi-mi:cenpa_human(display_long)|uniprotkb:CENPA(gene name)|psi-mi:CENPA(display_short)|uniprotkb:Centromere autoantigen A(gene name synonym)|uniprotkb:Centromere protein A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tasselli et al. (2016) pubmed:27043296|doi:10.1038/nsmb.3202|imex:IM-25405 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16203792|imex:IM-25405-1|dip:DIP-201081E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000077463(gene)|ensembl:ENST00000337491(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003247"(post-embryonic cardiac muscle cell growth involved in heart morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0003956"("NAD(P)+-protein-arginine ADP-ribosyltransferase activity")|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019213"(deacetylase activity)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031940"(obsolete positive regulation of chromatin silencing at telomere)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1905549"(obsolete positive regulation of subtelomeric heterochromatin assembly)|go:"GO:1905555"(positive regulation of blood vessel branching)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:3K35|rcsb pdb:3PKI|rcsb pdb:3PKJ|rcsb pdb:3ZG6|rcsb pdb:5MF6|rcsb pdb:5MFP|rcsb pdb:5MFZ|rcsb pdb:5MGN|rcsb pdb:5X16|rcsb pdb:5Y2F|rcsb pdb:6HOY|rcsb pdb:6QCD|rcsb pdb:6QCE|rcsb pdb:6QCH|rcsb pdb:6QCJ|rcsb pdb:6XUY|rcsb pdb:6XV1|rcsb pdb:6XV6|rcsb pdb:6XVG|rcsb pdb:6ZU4|rcsb pdb:7CL0|rcsb pdb:7CL1|reactome:R-HSA-1912408|reactome:R-HSA-5693607|refseq:NP_001180214.1|refseq:NP_057623.2|refseq:NP_001307987.1|refseq:NP_001307988.1|refseq:NP_001307989.1|refseq:NP_001307990.1|refseq:NP_001307991.1|refseq:NP_001307992.1|refseq:NP_001307993.1|dip:DIP-47346N refseq:NP_001035891.1|refseq:NP_001800.1|dip:DIP-52297N|ensembl:ENSG00000115163(gene)|ensembl:ENST00000335756(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:3AN2|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3R45|rcsb pdb:3WTP|rcsb pdb:5CVD|rcsb pdb:5Z23|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6KDQ|rcsb pdb:6KDS|rcsb pdb:6L49|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6TEM|rcsb pdb:7D20|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:r/bhvugj+nCc5ya3cg9qs2VuAJU9606 rogid:p+4MxwgHYHM9fpMXrAec/uZshTA9606 rigid:NNzEC+Ivmwb/7yOUF7k6am8kTEg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13263 intact:EBI-16203811 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 dip:DIP-61991N psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"h3(1027)"(display_short)|psi-mi:EBI-16203811(display_long) psi-mi:"MI:0096"(pull down) Tasselli et al. (2016) pubmed:27043296|doi:10.1038/nsmb.3202|imex:IM-25405 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16203856|imex:IM-25405-4|dip:DIP-201082E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rogid:1gpqfHjyhBjmYCpud7+VxgTG+8E-2 rigid:7r85WVyhfQENU9tXXts1CsON30Q false - N-acetylated L-lysine:9-9|biotin tag:0-0 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N6T7 intact:EBI-16203811 intact:EBI-712415|ensembl:ENSP00000337332|uniprotkb:O75291|uniprotkb:Q6IAF5|uniprotkb:Q6PK99|uniprotkb:Q8NCD2|uniprotkb:Q9BSI5|uniprotkb:Q9BWP3|uniprotkb:Q9NRC7|uniprotkb:Q9UQD1|uniprotkb:B2RCD0 dip:DIP-61991N psi-mi:sir6_human(display_long)|uniprotkb:SIR2-like protein 6(gene name synonym)|uniprotkb:SIRT6(gene name)|psi-mi:SIRT6(display_short)|uniprotkb:SIR2L6(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 6(gene name synonym) psi-mi:"h3(1027)"(display_short)|psi-mi:EBI-16203811(display_long) psi-mi:"MI:0406"(deacetylase assay) Tasselli et al. (2016) pubmed:27043296|doi:10.1038/nsmb.3202|imex:IM-25405 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0197"(deacetylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16203837|imex:IM-25405-3|dip:DIP-201084E - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSG00000077463(gene)|ensembl:ENST00000337491(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003247"(post-embryonic cardiac muscle cell growth involved in heart morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0003956"("NAD(P)+-protein-arginine ADP-ribosyltransferase activity")|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019213"(deacetylase activity)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031940"(obsolete positive regulation of chromatin silencing at telomere)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1905549"(obsolete positive regulation of subtelomeric heterochromatin assembly)|go:"GO:1905555"(positive regulation of blood vessel branching)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:3K35|rcsb pdb:3PKI|rcsb pdb:3PKJ|rcsb pdb:3ZG6|rcsb pdb:5MF6|rcsb pdb:5MFP|rcsb pdb:5MFZ|rcsb pdb:5MGN|rcsb pdb:5X16|rcsb pdb:5Y2F|rcsb pdb:6HOY|rcsb pdb:6QCD|rcsb pdb:6QCE|rcsb pdb:6QCH|rcsb pdb:6QCJ|rcsb pdb:6XUY|rcsb pdb:6XV1|rcsb pdb:6XV6|rcsb pdb:6XVG|rcsb pdb:6ZU4|rcsb pdb:7CL0|rcsb pdb:7CL1|reactome:R-HSA-1912408|reactome:R-HSA-5693607|refseq:NP_001180214.1|refseq:NP_057623.2|refseq:NP_001307987.1|refseq:NP_001307988.1|refseq:NP_001307989.1|refseq:NP_001307990.1|refseq:NP_001307991.1|refseq:NP_001307992.1|refseq:NP_001307993.1|dip:DIP-47346N - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:r/bhvugj+nCc5ya3cg9qs2VuAJU9606 rogid:1gpqfHjyhBjmYCpud7+VxgTG+8E-2 rigid:v3k0M2Z3jzTxCaiY/XKruBeOO0M false - N-acetylated L-lysine:9-9 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42568 intact:EBI-16203811 intact:EBI-716132|uniprotkb:B1AMQ2|uniprotkb:D3DRJ8|intact:EBI-11060385|ensembl:ENSP00000369695|intact:EBI-749963|uniprotkb:B2R7B3|uniprotkb:B7Z755|uniprotkb:Q8IVB0 dip:DIP-61991N psi-mi:af9_human(display_long)|uniprotkb:ALL1-fused gene from chromosome 9 protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein(gene name synonym)|uniprotkb:YEATS domain-containing protein 3(gene name synonym)|uniprotkb:MLLT3(gene name)|psi-mi:MLLT3(display_short)|uniprotkb:AF9(gene name synonym)|uniprotkb:YEATS3(gene name synonym) psi-mi:"h3(1027)"(display_short)|psi-mi:EBI-16203811(display_long) psi-mi:"MI:0096"(pull down) Tasselli et al. (2016) pubmed:27043296|doi:10.1038/nsmb.3202|imex:IM-25405 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16203878|imex:IM-25405-5|dip:DIP-201083E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_004520.2|refseq:NP_001273620.1|ensembl:ENSG00000171843(gene)|ensembl:ENST00000380338(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007379"(segment specification)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010467"(gene expression)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|mint:P42568|rcsb pdb:2LM0|rcsb pdb:2MV7|rcsb pdb:2N4Q|rcsb pdb:2NDF|rcsb pdb:2NDG|rcsb pdb:4TMP|rcsb pdb:5HJB|rcsb pdb:5HJD|rcsb pdb:5YYF|rcsb pdb:6B7G|rcsb pdb:6L5Z|rcsb pdb:6LS6|rcsb pdb:6MIL|rcsb pdb:6MIM|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|dip:DIP-56409N - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:Z+g2iDUI+CzIrL7bMjY11hYKywQ9606 rogid:1gpqfHjyhBjmYCpud7+VxgTG+8E-2 rigid:clZ6avIIZAiRpqBaShkrJcHLGUw false sufficient binding region:1-138 N-acetylated L-lysine:9-9|biotin tag:0-0 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)