#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q75760 uniprotkb:Q75760 intact:EBI-8453491|intact:MINT-8414778 intact:EBI-8453491|intact:MINT-8414778 psi-mi:q75760_9hiv1(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:q75760_9hiv1(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Lee et al. (2016) pubmed:26941313|doi:10.1126/science.aad2450|imex:IM-25437 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16201236|imex:IM-25437-1|dip:DIP-189981E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-59960N|mint:Q75760|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|go:"GO:1903911"(positive regulation of receptor clustering)|interpro:IPR000328(Envelope Polyprotein GP41)|interpro:IPR000777(Envelope glycoprotein GP120)|interpro:IPR036377|interpro:IPR037527|rcsb pdb:1TJG|rcsb pdb:2B4C|rcsb pdb:2F5B|rcsb pdb:3TYG|rcsb pdb:4JM2|rcsb pdb:5FYK dip:DIP-59960N|mint:Q75760|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|go:"GO:1903911"(positive regulation of receptor clustering)|interpro:IPR000328(Envelope Polyprotein GP41)|interpro:IPR000777(Envelope glycoprotein GP120)|interpro:IPR036377|interpro:IPR037527|rcsb pdb:1TJG|rcsb pdb:2B4C|rcsb pdb:2F5B|rcsb pdb:3TYG|rcsb pdb:4JM2|rcsb pdb:5FYK psi-mi:"MI:0465"(dip) comment:mint comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:pWtgmscRNmhME7uI5GwXyVWGA5811676 rogid:pWtgmscRNmhME7uI5GwXyVWGA5811676 rigid:84r+KkfquQ8JJ92tROFiG/7KbqE false sufficient binding region:31-655 sufficient binding region:31-655 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2N0S6 uniprotkb:Q2N0S6 intact:EBI-16080048 intact:EBI-16080048 psi-mi:q2n0s6_9hiv1(display_long)|uniprotkb:Env polyprotein(gene name synonym)|uniprotkb:env(gene name)|psi-mi:env(display_short) psi-mi:q2n0s6_9hiv1(display_long)|uniprotkb:Env polyprotein(gene name synonym)|uniprotkb:env(gene name)|psi-mi:env(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Lee et al. (2016) pubmed:26941313|doi:10.1126/science.aad2450|imex:IM-25437 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16201254|imex:IM-25437-2|dip:DIP-198807E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:1903911"(positive regulation of receptor clustering)|interpro:IPR000328(Envelope Polyprotein GP41)|interpro:IPR000777(Envelope glycoprotein GP120)|interpro:IPR036377|interpro:IPR037527|rcsb pdb:3J5M|rcsb pdb:4NCO|rcsb pdb:4ZMJ|rcsb pdb:5ACO|rcsb pdb:5C7K|rcsb pdb:5CEZ|rcsb pdb:5CJX|rcsb pdb:5D9Q|rcsb pdb:5FYL|rcsb pdb:5I8H|rcsb pdb:5JS9|rcsb pdb:5JSA|rcsb pdb:5T3S|rcsb pdb:5T3X|rcsb pdb:5T3Z|rcsb pdb:5THR|rcsb pdb:5U1F|rcsb pdb:5UTF|rcsb pdb:5UTY|rcsb pdb:5V7J|rcsb pdb:5V8L|rcsb pdb:5V8M|rcsb pdb:5VIY|rcsb pdb:5VJ6|rcsb pdb:5W6D|rcsb pdb:5WDU|rcsb pdb:6B0N|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|rcsb pdb:6CH7|rcsb pdb:6CH8|rcsb pdb:6CHB|rcsb pdb:6CUE|rcsb pdb:6CUF|rcsb pdb:6DFG|rcsb pdb:6DFH|rcsb pdb:6DID|rcsb pdb:6E5P|rcsb pdb:6MAR|rcsb pdb:6MN7|rcsb pdb:6MPG|rcsb pdb:6MPH|rcsb pdb:6MTJ|rcsb pdb:6MTN|rcsb pdb:6MU6|rcsb pdb:6MU7|rcsb pdb:6MU8|rcsb pdb:6N1V|rcsb pdb:6N1W|rcsb pdb:6NF2|rcsb pdb:6NF5|rcsb pdb:6NFC|rcsb pdb:6NM6|rcsb pdb:6NNF|rcsb pdb:6NNJ|rcsb pdb:6OPA|rcsb pdb:6ORN|rcsb pdb:6ORO|rcsb pdb:6ORP|rcsb pdb:6ORQ|rcsb pdb:6OSY|rcsb pdb:6OT1|rcsb pdb:6OZ4|rcsb pdb:6OZC|rcsb pdb:6P62|rcsb pdb:6P6F|rcsb pdb:6W03|rcsb pdb:6X9R|rcsb pdb:6PW6|rcsb pdb:6X9S|rcsb pdb:6U0L|rcsb pdb:6U0N|rcsb pdb:6X9T|rcsb pdb:6X9U|rcsb pdb:6X9V|rcsb pdb:6XRT|rcsb pdb:7KDE|rcsb pdb:7LL1|rcsb pdb:7LL2|rcsb pdb:7LO6|rcsb pdb:6UDJ|rcsb pdb:6UDK|rcsb pdb:7LOK|rcsb pdb:6UTK|rcsb pdb:6V0R|rcsb pdb:6V6W|rcsb pdb:6V8X|rcsb pdb:6V8Z|rcsb pdb:6VI0|rcsb pdb:6VKN|rcsb pdb:6VLR|rcsb pdb:6VN0|rcsb pdb:6VO0|rcsb pdb:6VO1|dip:DIP-61424N go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:1903911"(positive regulation of receptor clustering)|interpro:IPR000328(Envelope Polyprotein GP41)|interpro:IPR000777(Envelope glycoprotein GP120)|interpro:IPR036377|interpro:IPR037527|rcsb pdb:3J5M|rcsb pdb:4NCO|rcsb pdb:4ZMJ|rcsb pdb:5ACO|rcsb pdb:5C7K|rcsb pdb:5CEZ|rcsb pdb:5CJX|rcsb pdb:5D9Q|rcsb pdb:5FYL|rcsb pdb:5I8H|rcsb pdb:5JS9|rcsb pdb:5JSA|rcsb pdb:5T3S|rcsb pdb:5T3X|rcsb pdb:5T3Z|rcsb pdb:5THR|rcsb pdb:5U1F|rcsb pdb:5UTF|rcsb pdb:5UTY|rcsb pdb:5V7J|rcsb pdb:5V8L|rcsb pdb:5V8M|rcsb pdb:5VIY|rcsb pdb:5VJ6|rcsb pdb:5W6D|rcsb pdb:5WDU|rcsb pdb:6B0N|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|rcsb pdb:6CH7|rcsb pdb:6CH8|rcsb pdb:6CHB|rcsb pdb:6CUE|rcsb pdb:6CUF|rcsb pdb:6DFG|rcsb pdb:6DFH|rcsb pdb:6DID|rcsb pdb:6E5P|rcsb pdb:6MAR|rcsb pdb:6MN7|rcsb pdb:6MPG|rcsb pdb:6MPH|rcsb pdb:6MTJ|rcsb pdb:6MTN|rcsb pdb:6MU6|rcsb pdb:6MU7|rcsb pdb:6MU8|rcsb pdb:6N1V|rcsb pdb:6N1W|rcsb pdb:6NF2|rcsb pdb:6NF5|rcsb pdb:6NFC|rcsb pdb:6NM6|rcsb pdb:6NNF|rcsb pdb:6NNJ|rcsb pdb:6OPA|rcsb pdb:6ORN|rcsb pdb:6ORO|rcsb pdb:6ORP|rcsb pdb:6ORQ|rcsb pdb:6OSY|rcsb pdb:6OT1|rcsb pdb:6OZ4|rcsb pdb:6OZC|rcsb pdb:6P62|rcsb pdb:6P6F|rcsb pdb:6W03|rcsb pdb:6X9R|rcsb pdb:6PW6|rcsb pdb:6X9S|rcsb pdb:6U0L|rcsb pdb:6U0N|rcsb pdb:6X9T|rcsb pdb:6X9U|rcsb pdb:6X9V|rcsb pdb:6XRT|rcsb pdb:7KDE|rcsb pdb:7LL1|rcsb pdb:7LL2|rcsb pdb:7LO6|rcsb pdb:6UDJ|rcsb pdb:6UDK|rcsb pdb:7LOK|rcsb pdb:6UTK|rcsb pdb:6V0R|rcsb pdb:6V6W|rcsb pdb:6V8X|rcsb pdb:6V8Z|rcsb pdb:6VI0|rcsb pdb:6VKN|rcsb pdb:6VLR|rcsb pdb:6VN0|rcsb pdb:6VO0|rcsb pdb:6VO1|dip:DIP-61424N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:HmX+kzM9SON6lwqHzV2vdP6ug/g11676 rogid:HmX+kzM9SON6lwqHzV2vdP6ug/g11676 rigid:zTm+6UaayUFqawXm8dAUaAdpURs false sufficient binding region:30-683 sufficient binding region:30-683 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)