#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15118 uniprotkb:Q05320 intact:EBI-2368710|uniprotkb:Q9P130|uniprotkb:B4DET3|ensembl:ENSP00000269228 intact:EBI-16200230|uniprotkb:Q66818|uniprotkb:Q77LU5|uniprotkb:Q8B9S1|uniprotkb:Q8JS62 psi-mi:npc1_human(display_long)|uniprotkb:NPC1(gene name)|psi-mi:NPC1(display_short)|uniprotkb:Niemann-Pick C1 protein(gene name synonym) psi-mi:vgp_ebozm(display_long)|uniprotkb:GP(gene name)|psi-mi:GP(display_short)|uniprotkb:GP1,2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Misasi et al. (2016) pubmed:26917592|doi:10.1126/science.aad6117|imex:IM-25434 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16200270|imex:IM-25434-1|dip:DIP-201132E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000262.2|dip:DIP-53217N|ensembl:ENSG00000141458(gene)|ensembl:ENST00000269228(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0010467"(gene expression)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045121"(membrane raft)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004765(Niemann-Pick C type protein)|interpro:IPR032190|rcsb pdb:3GKH|rcsb pdb:3GKI|rcsb pdb:3GKJ|rcsb pdb:3JD8|rcsb pdb:5F18|rcsb pdb:5F1B|rcsb pdb:5HNS|rcsb pdb:5JNX|rcsb pdb:5KWY|rcsb pdb:5U73|rcsb pdb:5U74|rcsb pdb:6UOX|rcsb pdb:6W5R|rcsb pdb:6W5S|rcsb pdb:6W5T|rcsb pdb:6W5U|rcsb pdb:6W5V|reactome:R-HSA-8964038 go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR002561(Envelope glycoprotein precursor, extracellular region, filoviridae type)|interpro:IPR014625(Envelope glycoprotein precursor, Filoviridae type)|rcsb pdb:2EBO|rcsb pdb:2RLJ|rcsb pdb:3CSY|rcsb pdb:5FHC|rcsb pdb:5HJ3|rcsb pdb:5JQ3|rcsb pdb:5JQ7|rcsb pdb:5JQB|rcsb pdb:5KEL|rcsb pdb:5KEM|rcsb pdb:5KEN|rcsb pdb:6EA7|rcsb pdb:6EAY|rcsb pdb:6F5U|rcsb pdb:6F6I|rcsb pdb:6F6N|rcsb pdb:6F6S|rcsb pdb:6G95|rcsb pdb:6G9B|rcsb pdb:6G9I|rcsb pdb:6HRO|rcsb pdb:6HS4|rcsb pdb:6OZ9|rcsb pdb:6QD7|rcsb pdb:6QD8|rcsb pdb:6S8D|rcsb pdb:6VKM|rcsb pdb:7JPH|rcsb pdb:7JPI|refseq:NP_066246.1|dip:DIP-62002N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:3kG4MGzeShC2D5FsPoZZm1lEGlk9606 rogid:mdZH953i2elFKNtwJcAbPdm6Vvw128952 rigid:yBzb3vex8SqNYTALvU85qssIwzU false sufficient binding region:371-621|ha tag:n-n sufficient binding region:502-599,33-308 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q05320 uniprotkb:Q05320 intact:EBI-16200230|uniprotkb:Q66818|uniprotkb:Q77LU5|uniprotkb:Q8B9S1|uniprotkb:Q8JS62 intact:EBI-16200230|uniprotkb:Q66818|uniprotkb:Q77LU5|uniprotkb:Q8B9S1|uniprotkb:Q8JS62 psi-mi:vgp_ebozm(display_long)|uniprotkb:GP(gene name)|psi-mi:GP(display_short)|uniprotkb:GP1,2(gene name synonym) psi-mi:vgp_ebozm(display_long)|uniprotkb:GP(gene name)|psi-mi:GP(display_short)|uniprotkb:GP1,2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Misasi et al. (2016) pubmed:26917592|doi:10.1126/science.aad6117|imex:IM-25434 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16200314|imex:IM-25434-3|dip:DIP-201131E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR002561(Envelope glycoprotein precursor, extracellular region, filoviridae type)|interpro:IPR014625(Envelope glycoprotein precursor, Filoviridae type)|rcsb pdb:2EBO|rcsb pdb:2RLJ|rcsb pdb:3CSY|rcsb pdb:5FHC|rcsb pdb:5HJ3|rcsb pdb:5JQ3|rcsb pdb:5JQ7|rcsb pdb:5JQB|rcsb pdb:5KEL|rcsb pdb:5KEM|rcsb pdb:5KEN|rcsb pdb:6EA7|rcsb pdb:6EAY|rcsb pdb:6F5U|rcsb pdb:6F6I|rcsb pdb:6F6N|rcsb pdb:6F6S|rcsb pdb:6G95|rcsb pdb:6G9B|rcsb pdb:6G9I|rcsb pdb:6HRO|rcsb pdb:6HS4|rcsb pdb:6OZ9|rcsb pdb:6QD7|rcsb pdb:6QD8|rcsb pdb:6S8D|rcsb pdb:6VKM|rcsb pdb:7JPH|rcsb pdb:7JPI|refseq:NP_066246.1|dip:DIP-62002N go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR002561(Envelope glycoprotein precursor, extracellular region, filoviridae type)|interpro:IPR014625(Envelope glycoprotein precursor, Filoviridae type)|rcsb pdb:2EBO|rcsb pdb:2RLJ|rcsb pdb:3CSY|rcsb pdb:5FHC|rcsb pdb:5HJ3|rcsb pdb:5JQ3|rcsb pdb:5JQ7|rcsb pdb:5JQB|rcsb pdb:5KEL|rcsb pdb:5KEM|rcsb pdb:5KEN|rcsb pdb:6EA7|rcsb pdb:6EAY|rcsb pdb:6F5U|rcsb pdb:6F6I|rcsb pdb:6F6N|rcsb pdb:6F6S|rcsb pdb:6G95|rcsb pdb:6G9B|rcsb pdb:6G9I|rcsb pdb:6HRO|rcsb pdb:6HS4|rcsb pdb:6OZ9|rcsb pdb:6QD7|rcsb pdb:6QD8|rcsb pdb:6S8D|rcsb pdb:6VKM|rcsb pdb:7JPH|rcsb pdb:7JPI|refseq:NP_066246.1|dip:DIP-62002N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:mdZH953i2elFKNtwJcAbPdm6Vvw128952 rogid:mdZH953i2elFKNtwJcAbPdm6Vvw128952 rigid:hdJuNNnWIQNWvdVhZnQ4U6AxbP4 false sufficient binding region:502-599,33-308 sufficient binding region:502-599,33-308 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05320 uniprotkb:Q05320 intact:EBI-16200230|uniprotkb:Q66818|uniprotkb:Q77LU5|uniprotkb:Q8B9S1|uniprotkb:Q8JS62 intact:EBI-16200230|uniprotkb:Q66818|uniprotkb:Q77LU5|uniprotkb:Q8B9S1|uniprotkb:Q8JS62 psi-mi:vgp_ebozm(display_long)|uniprotkb:GP(gene name)|psi-mi:GP(display_short)|uniprotkb:GP1,2(gene name synonym) psi-mi:vgp_ebozm(display_long)|uniprotkb:GP(gene name)|psi-mi:GP(display_short)|uniprotkb:GP1,2(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Misasi et al. (2016) pubmed:26917592|doi:10.1126/science.aad6117|imex:IM-25434 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16200295|imex:IM-25434-2|dip:DIP-201131E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR002561(Envelope glycoprotein precursor, extracellular region, filoviridae type)|interpro:IPR014625(Envelope glycoprotein precursor, Filoviridae type)|rcsb pdb:2EBO|rcsb pdb:2RLJ|rcsb pdb:3CSY|rcsb pdb:5FHC|rcsb pdb:5HJ3|rcsb pdb:5JQ3|rcsb pdb:5JQ7|rcsb pdb:5JQB|rcsb pdb:5KEL|rcsb pdb:5KEM|rcsb pdb:5KEN|rcsb pdb:6EA7|rcsb pdb:6EAY|rcsb pdb:6F5U|rcsb pdb:6F6I|rcsb pdb:6F6N|rcsb pdb:6F6S|rcsb pdb:6G95|rcsb pdb:6G9B|rcsb pdb:6G9I|rcsb pdb:6HRO|rcsb pdb:6HS4|rcsb pdb:6OZ9|rcsb pdb:6QD7|rcsb pdb:6QD8|rcsb pdb:6S8D|rcsb pdb:6VKM|rcsb pdb:7JPH|rcsb pdb:7JPI|refseq:NP_066246.1|dip:DIP-62002N go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR002561(Envelope glycoprotein precursor, extracellular region, filoviridae type)|interpro:IPR014625(Envelope glycoprotein precursor, Filoviridae type)|rcsb pdb:2EBO|rcsb pdb:2RLJ|rcsb pdb:3CSY|rcsb pdb:5FHC|rcsb pdb:5HJ3|rcsb pdb:5JQ3|rcsb pdb:5JQ7|rcsb pdb:5JQB|rcsb pdb:5KEL|rcsb pdb:5KEM|rcsb pdb:5KEN|rcsb pdb:6EA7|rcsb pdb:6EAY|rcsb pdb:6F5U|rcsb pdb:6F6I|rcsb pdb:6F6N|rcsb pdb:6F6S|rcsb pdb:6G95|rcsb pdb:6G9B|rcsb pdb:6G9I|rcsb pdb:6HRO|rcsb pdb:6HS4|rcsb pdb:6OZ9|rcsb pdb:6QD7|rcsb pdb:6QD8|rcsb pdb:6S8D|rcsb pdb:6VKM|rcsb pdb:7JPH|rcsb pdb:7JPI|refseq:NP_066246.1|dip:DIP-62002N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:mdZH953i2elFKNtwJcAbPdm6Vvw128952 rogid:mdZH953i2elFKNtwJcAbPdm6Vvw128952 rigid:hdJuNNnWIQNWvdVhZnQ4U6AxbP4 false sufficient binding region:502-599,33-308 sufficient binding region:502-599,33-308 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05320 uniprotkb:Q05320 intact:EBI-16200230|uniprotkb:Q66818|uniprotkb:Q77LU5|uniprotkb:Q8B9S1|uniprotkb:Q8JS62 intact:EBI-16200230|uniprotkb:Q66818|uniprotkb:Q77LU5|uniprotkb:Q8B9S1|uniprotkb:Q8JS62 psi-mi:vgp_ebozm(display_long)|uniprotkb:GP(gene name)|psi-mi:GP(display_short)|uniprotkb:GP1,2(gene name synonym) psi-mi:vgp_ebozm(display_long)|uniprotkb:GP(gene name)|psi-mi:GP(display_short)|uniprotkb:GP1,2(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Misasi et al. (2016) pubmed:26917592|doi:10.1126/science.aad6117|imex:IM-25434 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16200333|imex:IM-25434-4|dip:DIP-201131E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR002561(Envelope glycoprotein precursor, extracellular region, filoviridae type)|interpro:IPR014625(Envelope glycoprotein precursor, Filoviridae type)|rcsb pdb:2EBO|rcsb pdb:2RLJ|rcsb pdb:3CSY|rcsb pdb:5FHC|rcsb pdb:5HJ3|rcsb pdb:5JQ3|rcsb pdb:5JQ7|rcsb pdb:5JQB|rcsb pdb:5KEL|rcsb pdb:5KEM|rcsb pdb:5KEN|rcsb pdb:6EA7|rcsb pdb:6EAY|rcsb pdb:6F5U|rcsb pdb:6F6I|rcsb pdb:6F6N|rcsb pdb:6F6S|rcsb pdb:6G95|rcsb pdb:6G9B|rcsb pdb:6G9I|rcsb pdb:6HRO|rcsb pdb:6HS4|rcsb pdb:6OZ9|rcsb pdb:6QD7|rcsb pdb:6QD8|rcsb pdb:6S8D|rcsb pdb:6VKM|rcsb pdb:7JPH|rcsb pdb:7JPI|refseq:NP_066246.1|dip:DIP-62002N go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR002561(Envelope glycoprotein precursor, extracellular region, filoviridae type)|interpro:IPR014625(Envelope glycoprotein precursor, Filoviridae type)|rcsb pdb:2EBO|rcsb pdb:2RLJ|rcsb pdb:3CSY|rcsb pdb:5FHC|rcsb pdb:5HJ3|rcsb pdb:5JQ3|rcsb pdb:5JQ7|rcsb pdb:5JQB|rcsb pdb:5KEL|rcsb pdb:5KEM|rcsb pdb:5KEN|rcsb pdb:6EA7|rcsb pdb:6EAY|rcsb pdb:6F5U|rcsb pdb:6F6I|rcsb pdb:6F6N|rcsb pdb:6F6S|rcsb pdb:6G95|rcsb pdb:6G9B|rcsb pdb:6G9I|rcsb pdb:6HRO|rcsb pdb:6HS4|rcsb pdb:6OZ9|rcsb pdb:6QD7|rcsb pdb:6QD8|rcsb pdb:6S8D|rcsb pdb:6VKM|rcsb pdb:7JPH|rcsb pdb:7JPI|refseq:NP_066246.1|dip:DIP-62002N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:mdZH953i2elFKNtwJcAbPdm6Vvw128952 rogid:mdZH953i2elFKNtwJcAbPdm6Vvw128952 rigid:hdJuNNnWIQNWvdVhZnQ4U6AxbP4 false sufficient binding region:502-599,33-308 sufficient binding region:502-599,33-308 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)