#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-19797	uniprotkb:O13563	dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96	intact:EBI-32948|uniprotkb:D6VZ57|ensemblfungi:YLR421C	psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:rpn13_yeast(display_long)|uniprotkb:RPN13(gene name)|psi-mi:RPN13(display_short)|uniprotkb:DAQ1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 13(gene name synonym)|uniprotkb:YLR421C(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16199830|imex:IM-25441-1|dip:DIP-201139E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI	sgd:S000004413|refseq:NP_013525.3|mint:O13563|dip:DIP-4637N|ensemblfungi:YLR421C(gene)|ensemblfungi:YLR421C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR038633|interpro:IPR044868|rcsb pdb:2Z4D|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30	psi-mi:"MI:0465"(dip)	no-uniprot-update:obsolete protein	crc64:752E8A12DC3799D4	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932	rogid:UDb5Hp4hH3QQ5iX7/9BtQVBO0FA559292	rigid:zHZ2uNVyV1IYHpchILSroVMqSS0	false	-	mutation disrupting interaction strength:93-93,45-45,43-43,42-42,41-41	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-4399559	uniprotkb:Q13200	dip:DIP-24261N	intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16199879|imex:IM-25441-3|dip:DIP-201143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606	rigid:SV6qJQnAPFNDxftyzmbF5J2KQ9k	false	ubiquitinylated lysine:48-48|ubiquitinylated lysine:6-6|ubiquitinylated lysine:11-11|ubiquitinylated lysine:27-27|ubiquitinylated lysine:29-29|ubiquitinylated lysine:33-33|ubiquitinylated lysine:63-63	sufficient binding region:404-617|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P38886	uniprotkb:P38634	intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9	intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79	psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name)	psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16199855|imex:IM-25441-2|dip:DIP-201141E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886	ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634	psi-mi:"MI:0465"(dip)	crc64:8A05198B0CD7C0C3	crc64:7913636340678F78	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292	rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292	rigid:/jZYzMYq36TxhZyPjsqClqXQ/+c	false	glutathione s tranferase tag:n-n	ubiquitinylated lysine:?-?|t7 tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32628	uniprotkb:P38764	intact:EBI-14668|uniprotkb:D3DLL2|ensemblfungi:YEL037C	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	psi-mi:rad23_yeast(display_long)|uniprotkb:SYGP-ORF29(orf name)|uniprotkb:YEL037C(locus name)|uniprotkb:RAD23(gene name)|psi-mi:RAD23(display_short)	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:"MI:0096"(pull down)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16199983|imex:IM-25441-7|dip:DIP-3881E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000763|ensemblfungi:YEL037C(gene)|ensemblfungi:YEL037C_mRNA(transcript)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|reactome:R-SCE-5696395|reactome:R-SCE-532668|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|rcsb pdb:1X3W|rcsb pdb:1X3Z|rcsb pdb:2NBU|rcsb pdb:2NBW|rcsb pdb:2QSF|rcsb pdb:2QSG|rcsb pdb:2QSH|rcsb pdb:3ESW|rcsb pdb:3M62|rcsb pdb:4YIR|rcsb pdb:6CFI|rcsb pdb:6UBF|interpro:IPR006636(Heat shock chaperonin-binding)|rcsb pdb:6UG1|rcsb pdb:6UIN|refseq:NP_010877.3|dip:DIP-1548N|mint:P32628	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	psi-mi:"MI:0465"(dip)	crc64:B3F0436DAB60B833	crc64:B77954F4A998BA7C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6Pl+Ctv8QBaoAY9m5xHv/qa/z7w559292	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rigid:UjsLKm358FsHhObFvd3NN0DGKUg	false	flag tag:c-c	glutathione s tranferase tag:n-n|mutation disrupting interaction strength:552-552,548-548,541-541	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P48510	uniprotkb:P38764	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16200009|imex:IM-25441-8|dip:DIP-18190E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	psi-mi:"MI:0465"(dip)	crc64:3F8691BB95E46569	crc64:B77954F4A998BA7C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rigid:MORjgirPfHeILV200u3OwUF+ffo	false	sufficient binding region:1-76	sufficient binding region:412-625	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O13563	uniprotkb:P38634	intact:EBI-32948|uniprotkb:D6VZ57|ensemblfungi:YLR421C	intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79	psi-mi:rpn13_yeast(display_long)|uniprotkb:RPN13(gene name)|psi-mi:RPN13(display_short)|uniprotkb:DAQ1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 13(gene name synonym)|uniprotkb:YLR421C(locus name)	psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16199959|imex:IM-25441-6|dip:DIP-201142E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004413|refseq:NP_013525.3|mint:O13563|dip:DIP-4637N|ensemblfungi:YLR421C(gene)|ensemblfungi:YLR421C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR038633|interpro:IPR044868|rcsb pdb:2Z4D|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30	ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634	psi-mi:"MI:0465"(dip)	crc64:752E8A12DC3799D4	crc64:7913636340678F78	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:UDb5Hp4hH3QQ5iX7/9BtQVBO0FA559292	rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292	rigid:JIg0rDEHxtbmCPrS2ES6lxvY8QM	false	glutathione s tranferase tag:n-n	ubiquitinylated lysine:?-?|t7 tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38764	intact:EBI-19797	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:"MI:0096"(pull down)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16200030|imex:IM-25441-9|dip:DIP-77418E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI	psi-mi:"MI:0465"(dip)	crc64:B77954F4A998BA7C	no-uniprot-update:obsolete protein	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932	rigid:aB7lvU6TAkCuN8tAFvOipLEl/rc	false	his tag:n-n	ubiquitinylated lysine:48-48|ubiquitinylated lysine:6-6|ubiquitinylated lysine:11-11|ubiquitinylated lysine:27-27|ubiquitinylated lysine:29-29|ubiquitinylated lysine:33-33|ubiquitinylated lysine:63-63	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32628	uniprotkb:P38764	intact:EBI-14668|uniprotkb:D3DLL2|ensemblfungi:YEL037C	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	psi-mi:rad23_yeast(display_long)|uniprotkb:SYGP-ORF29(orf name)|uniprotkb:YEL037C(locus name)|uniprotkb:RAD23(gene name)|psi-mi:RAD23(display_short)	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:"MI:0096"(pull down)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16199914|imex:IM-25441-4|dip:DIP-3881E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000763|ensemblfungi:YEL037C(gene)|ensemblfungi:YEL037C_mRNA(transcript)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|reactome:R-SCE-5696395|reactome:R-SCE-532668|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|rcsb pdb:1X3W|rcsb pdb:1X3Z|rcsb pdb:2NBU|rcsb pdb:2NBW|rcsb pdb:2QSF|rcsb pdb:2QSG|rcsb pdb:2QSH|rcsb pdb:3ESW|rcsb pdb:3M62|rcsb pdb:4YIR|rcsb pdb:6CFI|rcsb pdb:6UBF|interpro:IPR006636(Heat shock chaperonin-binding)|rcsb pdb:6UG1|rcsb pdb:6UIN|refseq:NP_010877.3|dip:DIP-1548N|mint:P32628	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	psi-mi:"MI:0465"(dip)	crc64:B3F0436DAB60B833	crc64:B77954F4A998BA7C	comment:Deletion of region 1-77 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6Pl+Ctv8QBaoAY9m5xHv/qa/z7w559292	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rigid:UjsLKm358FsHhObFvd3NN0DGKUg	false	flag tag:c-c	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38764	intact:EBI-19797	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16199938|imex:IM-25441-5|dip:DIP-77418E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI	psi-mi:"MI:0465"(dip)	crc64:B77954F4A998BA7C	no-uniprot-update:obsolete protein	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932	rigid:aB7lvU6TAkCuN8tAFvOipLEl/rc	false	sufficient binding region:482-612	ubiquitinylated lysine:48-48	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38634	uniprotkb:P38764	intact:EBI-17127|ensemblfungi:YLR079W|uniprotkb:D6VY79	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	psi-mi:sic1_yeast(display_long)|uniprotkb:SIC1(gene name)|psi-mi:SIC1(display_short)|uniprotkb:SDB25(gene name synonym)|uniprotkb:YLR079W(locus name)|uniprotkb:L9449.8(orf name)|uniprotkb:CDK inhibitor p40(gene name synonym)	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:"MI:0096"(pull down)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16200128|imex:IM-25441-13|dip:DIP-201140E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR079W(gene)|ensemblfungi:YLR079W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016242"(negative regulation of macroautophagy)|rcsb pdb:3V7D|rcsb pdb:6G86|refseq:NP_013180.1|sgd:S000004069|dip:DIP-6817N|mint:P38634	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	psi-mi:"MI:0465"(dip)	crc64:7913636340678F78	crc64:B77954F4A998BA7C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:qU8ivBCZHvG4VmXDxv52yc08Hwc559292	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rigid:eY/3OAjnalEBYbQ86pi5h8kLhmY	false	ubiquitinylated lysine:?-?|t7 tag:n-n	sufficient binding region:376-635|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38764	intact:EBI-19797	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16200104|imex:IM-25441-12|dip:DIP-77418E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI	psi-mi:"MI:0465"(dip)	crc64:B77954F4A998BA7C	no-uniprot-update:obsolete protein	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932	rigid:aB7lvU6TAkCuN8tAFvOipLEl/rc	false	sufficient binding region:412-625|mutation disrupting interaction strength:552-552,548-548,541-541	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32628	uniprotkb:P38764	intact:EBI-14668|uniprotkb:D3DLL2|ensemblfungi:YEL037C	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	psi-mi:rad23_yeast(display_long)|uniprotkb:SYGP-ORF29(orf name)|uniprotkb:YEL037C(locus name)|uniprotkb:RAD23(gene name)|psi-mi:RAD23(display_short)	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16200083|imex:IM-25441-11|dip:DIP-3881E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000763|ensemblfungi:YEL037C(gene)|ensemblfungi:YEL037C_mRNA(transcript)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|reactome:R-SCE-5696395|reactome:R-SCE-532668|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|rcsb pdb:1X3W|rcsb pdb:1X3Z|rcsb pdb:2NBU|rcsb pdb:2NBW|rcsb pdb:2QSF|rcsb pdb:2QSG|rcsb pdb:2QSH|rcsb pdb:3ESW|rcsb pdb:3M62|rcsb pdb:4YIR|rcsb pdb:6CFI|rcsb pdb:6UBF|interpro:IPR006636(Heat shock chaperonin-binding)|rcsb pdb:6UG1|rcsb pdb:6UIN|refseq:NP_010877.3|dip:DIP-1548N|mint:P32628	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	psi-mi:"MI:0465"(dip)	crc64:B3F0436DAB60B833	crc64:B77954F4A998BA7C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6Pl+Ctv8QBaoAY9m5xHv/qa/z7w559292	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rigid:UjsLKm358FsHhObFvd3NN0DGKUg	false	sufficient binding region:1-77	sufficient binding region:412-625	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38764	intact:EBI-19797	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16200064|imex:IM-25441-10|dip:DIP-77418E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI	psi-mi:"MI:0465"(dip)	crc64:B77954F4A998BA7C	no-uniprot-update:obsolete protein	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932	rigid:aB7lvU6TAkCuN8tAFvOipLEl/rc	false	sufficient binding region:482-612	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32628	uniprotkb:P38764	intact:EBI-14668|uniprotkb:D3DLL2|ensemblfungi:YEL037C	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	psi-mi:rad23_yeast(display_long)|uniprotkb:SYGP-ORF29(orf name)|uniprotkb:YEL037C(locus name)|uniprotkb:RAD23(gene name)|psi-mi:RAD23(display_short)	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16200154|imex:IM-25441-14|dip:DIP-3881E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000763|ensemblfungi:YEL037C(gene)|ensemblfungi:YEL037C_mRNA(transcript)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|reactome:R-SCE-5696395|reactome:R-SCE-532668|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|rcsb pdb:1X3W|rcsb pdb:1X3Z|rcsb pdb:2NBU|rcsb pdb:2NBW|rcsb pdb:2QSF|rcsb pdb:2QSG|rcsb pdb:2QSH|rcsb pdb:3ESW|rcsb pdb:3M62|rcsb pdb:4YIR|rcsb pdb:6CFI|rcsb pdb:6UBF|interpro:IPR006636(Heat shock chaperonin-binding)|rcsb pdb:6UG1|rcsb pdb:6UIN|refseq:NP_010877.3|dip:DIP-1548N|mint:P32628	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	psi-mi:"MI:0465"(dip)	crc64:B3F0436DAB60B833	crc64:B77954F4A998BA7C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6Pl+Ctv8QBaoAY9m5xHv/qa/z7w559292	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rigid:UjsLKm358FsHhObFvd3NN0DGKUg	false	sufficient binding region:1-77	sufficient binding region:412-625|mutation disrupting interaction strength:552-552,548-548,541-541	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38764	intact:EBI-19797	intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C	dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96	psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name)	psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:"MI:0096"(pull down)	Shi et al. (2016)	pubmed:26912900|doi:10.1126/science.aad9421|imex:IM-25441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16200180|imex:IM-25441-15|dip:DIP-77418E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764	sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI	psi-mi:"MI:0465"(dip)	crc64:B77954F4A998BA7C	no-uniprot-update:obsolete protein	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292	rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932	rigid:aB7lvU6TAkCuN8tAFvOipLEl/rc	false	sufficient binding region:412-625|mutation disrupting interaction strength:552-552,548-548,541-541|mutation disrupting interaction strength:552-552,548-548,541-541,517-517,514-514|glutathione s tranferase tag:n-n	ubiquitinylated lysine:48-48	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)