#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UBL3-3	uniprotkb:Q9UMN6	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197732|imex:IM-25359-1|dip:DIP-200944E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606	rigid:+8m9JlxVDz3YY780YfzwKsuEv6w	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	sufficient binding region:2575-2691	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:Q15291	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197732|imex:IM-25359-1|dip:DIP-200944E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:+8m9JlxVDz3YY780YfzwKsuEv6w	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:Q03164	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197758|imex:IM-25359-2|dip:DIP-200941E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rigid:w6fXX82pSkvk3elqeNckxBEhyOk	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	sufficient binding region:3754-3969	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:Q15291	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197758|imex:IM-25359-2|dip:DIP-200941E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:w6fXX82pSkvk3elqeNckxBEhyOk	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8NEZ4	uniprotkb:Q9UBL3-3	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197785|imex:IM-25359-3|dip:DIP-200943E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:kthTTOObyya907U61mX1eIoNWN4	false	sufficient binding region:4771-4887	sufficient binding region:286-505	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEZ4	uniprotkb:Q15291	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197785|imex:IM-25359-3|dip:DIP-200943E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:kthTTOObyya907U61mX1eIoNWN4	false	sufficient binding region:4771-4887	sufficient binding region:330-356	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03164	uniprotkb:Q9UBL3-3	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197903|imex:IM-25359-7|dip:DIP-200941E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:w6fXX82pSkvk3elqeNckxBEhyOk	false	sufficient binding region:3754-3969	sufficient binding region:286-505	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03164	uniprotkb:Q15291	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197903|imex:IM-25359-7|dip:DIP-200941E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:w6fXX82pSkvk3elqeNckxBEhyOk	false	sufficient binding region:3754-3969	sufficient binding region:330-356	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEZ4	uniprotkb:Q9UBL3-3	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197875|imex:IM-25359-6|dip:DIP-200947E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:pzEkSpl7LnuZl+NDaaR+gvlk3IM	false	sufficient binding region:4771-4887|mutation disrupting interaction strength:4806-4806	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UPS6-2	uniprotkb:Q9UBL3-3	intact:EBI-16197836|ensembl:ENSP00000442924	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:q9ups6-2(display_long)|uniprotkb:SETD1B(gene name)|psi-mi:SETD1B(display_short)|uniprotkb:KIAA1076(gene name synonym)|uniprotkb:KMT2G(gene name synonym)|uniprotkb:SET1B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2G(gene name synonym)|uniprotkb:SET domain-containing protein 1B(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197847|imex:IM-25359-5|dip:DIP-200949E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8836493(isoform-parent)|ensembl:ENSG00000139718(gene)|ensembl:ENST00000542440(transcript)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:8EjGdmc4Ko3+5cb3aTf9o8D8rmA9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:79OFe+6w60SrFY90HQ/WDRI/Ccg	false	sufficient binding region:1784-1901|mutation disrupting interaction strength:1819-1819	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8NEZ4	uniprotkb:Q15291	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197809|imex:IM-25359-4|dip:DIP-200943E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:kthTTOObyya907U61mX1eIoNWN4	false	sufficient binding region:4771-4887|glutathione s tranferase tag:n-n	mutation disrupting interaction strength:347-347	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8NEZ4	uniprotkb:Q9UBL3-3	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197809|imex:IM-25359-4|dip:DIP-200943E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:kthTTOObyya907U61mX1eIoNWN4	false	sufficient binding region:4771-4887|glutathione s tranferase tag:n-n	sufficient binding region:286-505	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O15047	uniprotkb:Q9UBL3-3	intact:EBI-540779|uniprotkb:A6NP62|uniprotkb:Q6PIF3|uniprotkb:Q8TAJ6|intact:EBI-28969638|ensembl:ENSP00000262519|ensembl:ENSP00000507683	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:set1a_human(display_long)|uniprotkb:KMT2F(gene name synonym)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Set1/Ash2 histone methyltransferase complex subunit SET1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2F(gene name synonym)|uniprotkb:SETD1A(gene name)|psi-mi:SETD1A(display_short)|uniprotkb:KIAA0339(gene name synonym)|uniprotkb:SET1(gene name synonym)|uniprotkb:SET1A(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197927|imex:IM-25359-8|dip:DIP-200948E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055527.1|refseq:XP_006721169.1|ensembl:ENSP00000262519|ensembl:ENSP00000507683|reactome:R-HSA-8936459|reactome:R-HSA-3214841|ensembl:ENSG00000099381(gene)|ensembl:ENST00000262519(transcript)|ensembl:ENST00000684162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|mint:O15047|go:"GO:0048188"(Set1C/COMPASS complex)|rcsb pdb:3S8S|rcsb pdb:3UVN|rcsb pdb:4EWR|refseq:XP_005255780.1|refseq:XP_016879398.1|dip:DIP-33494N	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:nx0uWEVFas1w2NmuG73lCObAULE9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:t1klBU9CctHnm6RojS53fHDhk/U	false	sufficient binding region:1568-1685|mutation disrupting interaction strength:1603-1603	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q03164	uniprotkb:Q9UBL3-3	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197955|imex:IM-25359-9|dip:DIP-83296E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:Ias/P6hX17jrJlRF0QJwHrfI49U	false	sufficient binding region:3754-3969|mutation disrupting interaction strength:3864-3864	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q03164	uniprotkb:Q9UBL3-3	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197984|imex:IM-25359-10|dip:DIP-200941E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:w6fXX82pSkvk3elqeNckxBEhyOk	false	sufficient binding region:3754-3969	sufficient binding region:286-505	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03164	uniprotkb:Q15291	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16197984|imex:IM-25359-10|dip:DIP-200941E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:w6fXX82pSkvk3elqeNckxBEhyOk	false	sufficient binding region:3754-3969	sufficient binding region:330-356	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UBL3-3	uniprotkb:O14686	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198008|imex:IM-25359-11|dip:DIP-200942E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606	rigid:P/sgW1SrKVfM73WpxANPcAQnEr4	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	sufficient binding region:5397-5513	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:Q15291	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198008|imex:IM-25359-11|dip:DIP-200942E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:P/sgW1SrKVfM73WpxANPcAQnEr4	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O14686	uniprotkb:Q9UBL3-3	intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198034|imex:IM-25359-12|dip:DIP-84091E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:nZ86y7REeEcmnYkfuZuoU7/gNn4	false	sufficient binding region:5397-5513|mutation disrupting interaction strength:5432-5432	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:O15047	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-540779|uniprotkb:A6NP62|uniprotkb:Q6PIF3|uniprotkb:Q8TAJ6|intact:EBI-28969638|ensembl:ENSP00000262519|ensembl:ENSP00000507683	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:set1a_human(display_long)|uniprotkb:KMT2F(gene name synonym)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Set1/Ash2 histone methyltransferase complex subunit SET1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2F(gene name synonym)|uniprotkb:SETD1A(gene name)|psi-mi:SETD1A(display_short)|uniprotkb:KIAA0339(gene name synonym)|uniprotkb:SET1(gene name synonym)|uniprotkb:SET1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198062|imex:IM-25359-13|dip:DIP-200945E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	refseq:NP_055527.1|refseq:XP_006721169.1|ensembl:ENSP00000262519|ensembl:ENSP00000507683|reactome:R-HSA-8936459|reactome:R-HSA-3214841|ensembl:ENSG00000099381(gene)|ensembl:ENST00000262519(transcript)|ensembl:ENST00000684162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|mint:O15047|go:"GO:0048188"(Set1C/COMPASS complex)|rcsb pdb:3S8S|rcsb pdb:3UVN|rcsb pdb:4EWR|refseq:XP_005255780.1|refseq:XP_016879398.1|dip:DIP-33494N	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:nx0uWEVFas1w2NmuG73lCObAULE9606	rigid:C/9/8Oxy1/scUvrFhqK2BMDCNQ4	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	sufficient binding region:1568-1685	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:Q15291	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198062|imex:IM-25359-13|dip:DIP-200945E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:C/9/8Oxy1/scUvrFhqK2BMDCNQ4	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UMN6	uniprotkb:Q9UBL3-3	intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198088|imex:IM-25359-14|dip:DIP-192655E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:t1bw3JCga2O8Gh1kcd+sTNivqwk	false	sufficient binding region:2575-2691|mutation disrupting interaction strength:2610-2610	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q15291	uniprotkb:Q9UBL3-3	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198116|imex:IM-25359-15|dip:DIP-84094E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:Ne2oJlud8/C7Z5+BFqfEe9jf3lI	false	sufficient binding region:330-381|glutathione s tranferase tag:n-n	sufficient binding region:286-505|mutation disrupting interaction strength:343-343|mutation disrupting interaction strength:367-367	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:Q8NEZ4	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198145|imex:IM-25359-16|dip:DIP-200943E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rigid:kthTTOObyya907U61mX1eIoNWN4	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	sufficient binding region:4771-4887	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:Q15291	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198145|imex:IM-25359-16|dip:DIP-200943E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:kthTTOObyya907U61mX1eIoNWN4	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8NEZ4	uniprotkb:Q9UBL3-3	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198197|imex:IM-25359-18|dip:DIP-200943E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:kthTTOObyya907U61mX1eIoNWN4	false	sufficient binding region:4771-4887	sufficient binding region:286-505	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEZ4	uniprotkb:Q15291	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198197|imex:IM-25359-18|dip:DIP-200943E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:kthTTOObyya907U61mX1eIoNWN4	false	sufficient binding region:4771-4887	sufficient binding region:330-356	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UBL3-3	uniprotkb:Q9UPS6-2	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-16197836|ensembl:ENSP00000442924	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:q9ups6-2(display_long)|uniprotkb:SETD1B(gene name)|psi-mi:SETD1B(display_short)|uniprotkb:KIAA1076(gene name synonym)|uniprotkb:KMT2G(gene name synonym)|uniprotkb:SET1B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2G(gene name synonym)|uniprotkb:SET domain-containing protein 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198171|imex:IM-25359-17|dip:DIP-200946E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	intact:EBI-8836493(isoform-parent)|ensembl:ENSG00000139718(gene)|ensembl:ENST00000542440(transcript)	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:8EjGdmc4Ko3+5cb3aTf9o8D8rmA9606	rigid:MZyF0C4OPI90ycqEhy698SWtpjA	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	sufficient binding region:1784-1901	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UBL3-3	uniprotkb:Q15291	intact:EBI-16130425|ensembl:ENSP00000395310	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198171|imex:IM-25359-17|dip:DIP-200946E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:MZyF0C4OPI90ycqEhy698SWtpjA	false	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q15291	uniprotkb:Q9UBL3-3	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198221|imex:IM-25359-19|dip:DIP-84094E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:Ne2oJlud8/C7Z5+BFqfEe9jf3lI	false	sufficient binding region:330-356	sufficient binding region:286-505	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15291	uniprotkb:Q9UBL3-3	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	intact:EBI-16130425|ensembl:ENSP00000395310	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2016)	pubmed:26886794|doi:10.1038/nature16952|imex:IM-25359	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16198242|imex:IM-25359-20|dip:DIP-84094E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606	rigid:Ne2oJlud8/C7Z5+BFqfEe9jf3lI	false	mutation decreasing interaction strength:356-356|mutation disrupting interaction strength:353-353|mutation disrupting interaction strength:349-349	glutathione s tranferase tag:?-?|sufficient binding region:286-505	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)