#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P70326	uniprotkb:P70288	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-302251|uniprotkb:B2RRP3	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16359962|imex:IM-26212-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Figure 1G|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2017/08/22	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:bGLIDKTlyhBz40NViC8calRacZ010090	rigid:xIO+qTsbIVYP3gHb7g559eLujmA	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70326	uniprotkb:Q8K4B0	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-1216353|uniprotkb:Q80UI1|uniprotkb:Q8K4D4|uniprotkb:Q924K9|ensembl:ENSMUSP00000009099	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:mta1_mouse(display_long)|uniprotkb:Mta1(gene name)|psi-mi:Mta1(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16359962|imex:IM-26212-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:XP_006515485.1|dip:DIP-38226N|ensembl:ENSMUSG00000021144(gene)|ensembl:ENSMUST00000009099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|reactome:R-MMU-3214815|reactome:R-MMU-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033363"(secretory granule organization)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q8K4B0|reactome:R-MMU-73762|reactome:R-MMU-8943724	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Figure 1G|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2017/08/22	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:5DvgpUkohteacGjUvdFq7C+fU2w10090	rigid:xIO+qTsbIVYP3gHb7g559eLujmA	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70326	uniprotkb:Q6PDQ2	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-3043852|ensembl:ENSMUSP00000060054	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16359962|imex:IM-26212-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Figure 1G|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2017/08/22	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090	rigid:xIO+qTsbIVYP3gHb7g559eLujmA	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70326	uniprotkb:Q6PDQ2	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-3043852|ensembl:ENSMUSP00000060054	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360004|imex:IM-26212-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N	-	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Figure 1H|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_heart)|taxid:10090(mouse embryonic heart)	-	2017/08/16	2017/08/16	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090	rigid:Nlq7PNFPAzqjr6Dd34pXdUe+EQ4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70326	uniprotkb:Q6WKZ7	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-1391878|uniprotkb:Q7TSK5|uniprotkb:Q8BWC2|ensembl:ENSMUSP00000036923	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:nostn_mouse(display_long)|uniprotkb:Nostrin(gene name)|psi-mi:Nostrin(display_short)|uniprotkb:Daip2(gene name synonym)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Disabled homolog 2-interacting protein 2(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_853525.3|ensembl:ENSMUSG00000034738(gene)|ensembl:ENSMUST00000041865(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|mint:Q6WKZ7|reactome:R-MMU-203641	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:sYY/6zoWydoVacJ+I+OdFBAvFt810090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q6PDG5	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-3870565|uniprotkb:Q6P6P3|ensembl:ENSMUSP00000100868	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:smrc2_mouse(display_long)|uniprotkb:Smarcc2(gene name)|psi-mi:Smarcc2(display_short)|uniprotkb:Baf170(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001107568.1|refseq:NP_001107569.1|refseq:NP_937803.1|dip:DIP-48884N|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0042393"(histone binding)|ensembl:ENSMUSG00000025369(gene)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q6PDG5|reactome:R-MMU-3214858|reactome:R-MMU-8939243|ensembl:ENSMUST00000105235(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:v8cjo/1nUFl5vd96cKMcY8LA8M010090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8BKT7	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8341251|intact:MINT-4111331|uniprotkb:Q8CHR3|uniprotkb:Q69ZU0	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:thoc5_mouse(display_long)|uniprotkb:Thoc5(gene name)|psi-mi:Thoc5(display_short)|uniprotkb:Fmip(gene name synonym)|uniprotkb:Kiaa0983(gene name synonym)|uniprotkb:Fms-interacting protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_766026.1|interpro:IPR019163|mint:Q8BKT7|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001824"(blastocyst development)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0017145"(stem cell division)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000035"(regulation of stem cell division)|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	function:May be involved in the differentiation of granulocytes and adipocytes|comment:mint	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:2BPGcX+Efvb2o67V17No87ke2rM10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q69Z99	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8338783|uniprotkb:Q3UJQ0|uniprotkb:Q3U365|intact:MINT-4110900|uniprotkb:Q5FWY0|uniprotkb:Q3UDU3|uniprotkb:Q8BJF3|ensembl:ENSMUSP00000075613	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:zn512_mouse(display_long)|uniprotkb:Znf512(gene name)|psi-mi:Znf512(display_short)|uniprotkb:Kiaa1805(gene name synonym)|uniprotkb:Zfp512(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_766581.2|ensembl:ENSMUSG00000062761(gene)|ensembl:ENSMUST00000076264(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q69Z99	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:vVo4NxC/Xu//HLdwQaWynLjymAo10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:O88291	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8338448|uniprotkb:Q3UJI3|uniprotkb:Q8K1X9|uniprotkb:Q05DP5|uniprotkb:Q3TRI9|uniprotkb:Q8BSJ5|uniprotkb:Q9CYG9|intact:MINT-4105453	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:zn326_mouse(display_long)|uniprotkb:Znf326(gene name)|psi-mi:Znf326(display_short)|uniprotkb:Zan75(gene name synonym)|uniprotkb:Zfp326(gene name synonym)|uniprotkb:Zinc finger protein 326(gene name synonym)|uniprotkb:Zinc finger protein interacting with mRNPs(gene name synonym)|uniprotkb:Zird(gene name synonym)|uniprotkb:Zinc finger protein-associated with nuclear matrix of 75 kDa(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_061229.2|mint:O88291|dip:DIP-58947N|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint|function:Probable transcriptional activator which may play a role in neuronal differentiation. Able to bind DNA and activate expression in vitro	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:zN3bSkPnoWXOBXTrdNy4E+ICJ2E10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q61510	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8377742|uniprotkb:Q5SU70|intact:MINT-240797|ensembl:ENSMUSP00000103528	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:tri25_mouse(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)|uniprotkb:Trim25(gene name)|psi-mi:Trim25(display_short)|uniprotkb:Efp(gene name synonym)|uniprotkb:Zfp147(gene name synonym)|uniprotkb:Znf147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_033572.2|ensembl:ENSMUSG00000000275(gene)|ensembl:ENSMUST00000107896(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q61510|rcsb pdb:4B8E|reactome:R-MMU-1169408|reactome:R-MMU-5656169	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint|function:Mediates estrogen action in various target organs	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:JcdARiyxwQkDwoYPAJUmsvH8ri810090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:P70326	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q9D3E6	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8430060|uniprotkb:O08982|intact:MINT-4135756|uniprotkb:Q6P5D1|ensembl:ENSMUSP00000116205	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:stag1_mouse(display_long)|uniprotkb:Stag1(gene name)|psi-mi:Stag1(display_short)|uniprotkb:Sa1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_033308.2|refseq:XP_006510986.1|refseq:XP_006510987.1|ensembl:ENSMUSG00000037286(gene)|ensembl:ENSMUST00000129269(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q9D3E6|reactome:R-MMU-2467813|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	function:Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis|comment:mint	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:s1WGi5ZDTZuZS4q0KFS/tvL+FXk10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q0VBL3	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8572651|intact:EBI-11518552|intact:EBI-9989873|intact:EBI-16360075|uniprotkb:A0PJG5|uniprotkb:Q3THK4|uniprotkb:Q3TLX0|uniprotkb:Q571M7|uniprotkb:Q66JP8|uniprotkb:Q6PGG1|uniprotkb:Q7TT82|ensembl:ENSMUSP00000054424|intact:MINT-8174194	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:rbm15_mouse(display_long)|uniprotkb:Kiaa4257(gene name synonym)|uniprotkb:One-twenty two protein 1(gene name synonym)|uniprotkb:Ott1(gene name synonym)|uniprotkb:RNA-binding motif protein 15(gene name synonym)|uniprotkb:Rbm15(gene name)|psi-mi:Rbm15(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001039272.1|ensembl:ENSMUSG00000048109(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0038163"(thrombopoietin-mediated signaling pathway)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|ensembl:ENSMUST00000061772(transcript)|go:"GO:0048536"(spleen development)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034470|interpro:IPR034472|interpro:IPR034473|interpro:IPR035979	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:09qhcrNbUkJFdyi2RiYw3SDXVW410090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q02780	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8339237|intact:MINT-4103569|uniprotkb:P70251|uniprotkb:P70250|uniprotkb:Q9R1G5|uniprotkb:Q8VBT5|uniprotkb:Q61960|uniprotkb:Q3UUZ2	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:nfia_mouse(display_long)|uniprotkb:Nfia(gene name)|psi-mi:Nfia(display_short)|uniprotkb:Nuclear factor I/A(gene name synonym)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001116425.1|interpro:IPR019739|interpro:IPR020604|refseq:NP_035035.1|refseq:NP_001116424.1|interpro:IPR019548|refseq:XP_006502905.1|mint:Q02780|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030054"(cell junction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060074"(synapse maturation)|go:"GO:0072189"(ureter development)|interpro:IPR000647(CTF/NF-I)|interpro:IPR003619(MAD homology 1, Dwarfin-type)	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint|function:Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:0jGlEKxrqI05c+6eGfOp2wMVi+Y10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8C1D8	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8387298|uniprotkb:Q3UWB0|uniprotkb:Q8BY73|uniprotkb:Q6NVD1|uniprotkb:Q9D9H4|intact:MINT-4114051|uniprotkb:Q3TQ25|ensembl:ENSMUSP00000025243	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:iws1_mouse(display_long)|uniprotkb:Iws1(gene name)|psi-mi:Iws1(display_short)|uniprotkb:Iws1l(gene name synonym)|uniprotkb:IWS1-like protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_775617.1|ensembl:ENSMUSG00000024384(gene)|ensembl:ENSMUST00000025243(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0090239"(regulation of histone H4 acetylation)|go:"GO:2001253"(regulation of histone H3-K36 trimethylation)|interpro:IPR017923|interpro:IPR035441|mint:Q8C1D8|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:r9aQ40EqQpf32tyzOSEBZYOT4CY10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8BGC0	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8317437|ensembl:ENSMUSP00000086027|uniprotkb:B1AVC7|uniprotkb:Q9DAU3|intact:MINT-4110261|uniprotkb:Q9CT41|uniprotkb:Q1WWK0	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:htsf1_mouse(display_long)|uniprotkb:Htatsf1(gene name)|psi-mi:Htatsf1(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUST00000088652(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:Q8BGC0|ensembl:ENSMUSG00000067873(gene)|refseq:NP_083647.1|refseq:NP_082518.1|dip:DIP-46367N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint|function:Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:sNRVG8L858Z4Q5Y0CkP2Bc2K7fU10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8CH25	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8314778|ensembl:ENSMUSP00000049112|uniprotkb:Q8BR40|uniprotkb:Q9CS57|uniprotkb:Q8VCF4|uniprotkb:Q3UYE5|intact:MINT-4115860|uniprotkb:Q8BP76	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:sltm_mouse(display_long)|uniprotkb:Sltm(gene name)|psi-mi:Sltm(display_short)|uniprotkb:Met(gene name synonym)|uniprotkb:Modulator of estrogen-induced transcription(gene name synonym)|uniprotkb:SAF-like transcription modulator(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000032212(gene)|ensembl:ENSMUST00000049263(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034780|interpro:IPR035979|interpro:IPR036361|mint:Q8CH25|refseq:NP_080613.1|refseq:NP_079966.2	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:MmIaktCmPhynmaBFQARrYE6oGfQ10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q9JJF3	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-7608809|intact:MINT-4130008|uniprotkb:B2RQV2|ensembl:ENSMUSP00000057984	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:riox1_mouse(display_long)|uniprotkb:Riox1(gene name)|psi-mi:Riox1(display_short)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:Mapjd(gene name synonym)|uniprotkb:No66(gene name synonym)|uniprotkb:MNCb-7109(orf name)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_076122.2|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|ensembl:ENSMUSG00000046791(gene)|ensembl:ENSMUST00000053744(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9JJF3	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:mint|function:May play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:wit6Jw/c30AHqUrI5iSJKEs8kVk10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:P56960	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-8316161|ensembl:ENSMUSP00000017408|uniprotkb:B1ARY9|uniprotkb:Q9R0B1|intact:MINT-4094804|uniprotkb:Q9QYS8	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:exosx_mouse(display_long)|uniprotkb:Exosc10(gene name)|psi-mi:Exosc10(display_short)|uniprotkb:Pmscl2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2 homolog(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2 homolog(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000017264(gene)|ensembl:ENSMUST00000017408(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:P56960|reactome:R-MMU-6791226|refseq:NP_057908.2	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	function:"Part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Could be an exonuclease. Mediates the association of MTR4, C1D and MPP6 wth the exosome and this complex is required for the maturation of 5.8S rRNA. Required for nucleolar localization of C1D"|comment:mint	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:0d5mjwJWcKJp1FOOShsVURcgLYg10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:D3YXK2	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-539539|ensembl:ENSMUSP00000092849	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:safb1_mouse(display_long)|uniprotkb:Safb(gene name)|psi-mi:Safb(display_short)|uniprotkb:Safb1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001156772.1|ensembl:ENSMUST00000095224(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030496"(midbody)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0040008"(regulation of growth)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034781|interpro:IPR035979|interpro:IPR036361|mint:D3YXK2|ensembl:ENSMUSG00000071054(gene)|reactome:R-MMU-3899300	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	comment:Author screened murine library then identified protein by homology to rat. Currently no murine sequence in database.	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:wGs3hvKUEDoWR83eBl9+qv4JWzs10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:P17012	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-16360118|ensembl:ENSMUSP00000085423|ensembl:ENSMUSP00000109559|ensembl:ENSMUSP00000109560|uniprotkb:P17011	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:zfx_mouse(display_long)|uniprotkb:Zfx(gene name)|psi-mi:Zfx(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000079509(gene)|ensembl:ENSMUST00000088102(transcript)|ensembl:ENSMUST00000113926(transcript)|ensembl:ENSMUST00000113927(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0009791"(post-embryonic development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060746"(parental behavior)|interpro:IPR006794(Zfx / Zfy transcription activation region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P17012|refseq:NP_001037851.1|refseq:NP_035898.2|refseq:XP_006528029.1|refseq:XP_011245879.1|refseq:XP_011245880.1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:FkIURapAxen8c3qWW9P3PecSTYk10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q61029	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-6172136|ensembl:ENSMUSP00000072092|uniprotkb:Q3UCI5|uniprotkb:Q61030|uniprotkb:Q61031|uniprotkb:Q61032	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:lap2b_mouse(display_long)|uniprotkb:Tmpo(gene name)|psi-mi:Tmpo(display_short)|uniprotkb:Lap2(gene name synonym)|uniprotkb:Thymopoietin isoforms beta/delta/epsilon/gamma(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000019961(gene)|ensembl:ENSMUST00000072239(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:Q61029|refseq:NP_001073598.1|refseq:NP_001073600.1|refseq:NP_001073601.1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:Gjr5NZyUa8Moc4L8lJlRPq29mQE10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q5U4C3	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-16360097|ensembl:ENSMUSP00000082501|ensembl:ENSMUSP00000148251|uniprotkb:Q3UR01	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:sfr19_mouse(display_long)|uniprotkb:SR-related and CTD-associated factor 1(gene name synonym)|uniprotkb:Scaf1(gene name)|psi-mi:Scaf1(display_short)|uniprotkb:Sfrs19(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000038406(gene)|ensembl:ENSMUST00000085383(transcript)|ensembl:ENSMUST00000211735(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|interpro:IPR042841|refseq:NP_001008422.1|refseq:XP_006540884.1|refseq:XP_011249157.1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:53uc4rvcetYN/+EV85AzDiULqPg10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8C2Q3	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-5692318|uniprotkb:Q3TJB6|uniprotkb:Q91Z21|uniprotkb:Q9DBI6|ensembl:ENSMUSP00000006625	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:rbm14_mouse(display_long)|uniprotkb:Rbm14(gene name)|psi-mi:Rbm14(display_short)|uniprotkb:RNA-binding motif protein 14(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_063922.2|dip:DIP-58946N|ensembl:ENSMUSG00000006456(gene)|ensembl:ENSMUST00000006625(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0098534"(centriole assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|interpro:IPR035979|mint:Q8C2Q3|reactome:R-MMU-8941326	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:0jBdPL/CBCwYLIf2A76qx0yJ9RY10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:O54724	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-645496|uniprotkb:Q2TAW6|ensembl:ENSMUSP00000058321	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:cavn1_mouse(display_long)|uniprotkb:Cavin1(gene name)|psi-mi:Cavin1(display_short)|uniprotkb:Cav-p60(gene name synonym)|uniprotkb:Cavin-1(gene name synonym)|uniprotkb:Polymerase I and transcript release factor(gene name synonym)|uniprotkb:Ptrf(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_033012.1|dip:DIP-40506N|ensembl:ENSMUSG00000004044(gene)|ensembl:ENSMUST00000060792(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009306"(protein secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR026752|interpro:IPR033297|mint:O54724|rcsb pdb:4QKV|reactome:R-MMU-73863|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:hPJHFyrpyl5yz+7Brojuu3W2bEA10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q80WJ7	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-774530|uniprotkb:Q3U9F8|uniprotkb:Q3UAQ8|uniprotkb:Q8BN67|uniprotkb:Q8CBT9|uniprotkb:Q8CDL0|uniprotkb:B2RSG8|uniprotkb:Q05CM0|uniprotkb:Q8CGI7|uniprotkb:Q9D052|ensembl:ENSMUSP00000022865	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:lyric_mouse(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Mtdh(gene name)|psi-mi:Mtdh(display_short)|uniprotkb:Lyric(gene name synonym)|uniprotkb:Metadherin(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_080278.3|ensembl:ENSMUSG00000022255(gene)|ensembl:ENSMUST00000022865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR031402|mint:Q80WJ7	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:AwHgSmY3V6vCx2st1bunWPSPIM810090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q60749	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-519077|uniprotkb:A2ACH3|uniprotkb:Q7M4N5|uniprotkb:Q3U8T3|uniprotkb:Q60735|uniprotkb:Q99M33|ensembl:ENSMUSP00000066516|ensembl:ENSMUSP00000115402|uniprotkb:B2KG38	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:khdr1_mouse(display_long)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:Khdrbs1(gene name)|psi-mi:Khdrbs1(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000028790(gene)|ensembl:ENSMUST00000066257(transcript)|ensembl:ENSMUST00000129342(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q60749|reactome:R-MMU-8849468|refseq:NP_035447.3|dip:DIP-2861N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:FtKudvPZeoFATHi0fUbnPsJgons10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q62318	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-346909|uniprotkb:P70391|uniprotkb:Q8C283|uniprotkb:Q99PN4|ensembl:ENSMUSP00000005705	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:tif1b_mouse(display_long)|uniprotkb:Trim28(gene name)|psi-mi:Trim28(display_short)|uniprotkb:Krip1(gene name synonym)|uniprotkb:Tif1b(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:KRAB-A-interacting protein(gene name synonym)|uniprotkb:KRIP-1(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:Kap1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_035718.2|dip:DIP-31477N|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q62318|rcsb pdb:6O5K|reactome:R-MMU-212436|ensembl:ENSMUSG00000005566(gene)|ensembl:ENSMUST00000005705(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:DvGJxQNohVWs++QEAyrqe4ngcz810090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q04750	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-6666222|ensembl:ENSMUSP00000105094|uniprotkb:A2A4B7	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:top1_mouse(display_long)|uniprotkb:Top1(gene name)|psi-mi:Top1(display_short)|uniprotkb:Top-1(gene name synonym)|uniprotkb:DNA topoisomerase I(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000070544(gene)|ensembl:ENSMUST00000109468(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0003682"(chromatin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|reactome:R-MMU-4615885|mint:Q04750|refseq:NP_033434.2	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:nY84yAtfGCI/k+B2u3mM151r+zU10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q921F2	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-6876933|ensembl:ENSMUSP00000081142|uniprotkb:Q3U591|uniprotkb:Q3V0E7	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:tadbp_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:Tdp43(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000084125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q921F2|rcsb pdb:3D2W|refseq:NP_663531.1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:j1U3NZd8O/lAclOPSRt10NY58e810090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q62311	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-5744190|ensembl:ENSMUSP00000048016|ensembl:ENSMUSP00000106561	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:taf6_mouse(display_long)|uniprotkb:Taf6(gene name)|psi-mi:Taf6(display_short)|uniprotkb:Taf2e(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 70 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 80 kDa subunit(gene name synonym)|uniprotkb:p80(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000036980(gene)|ensembl:ENSMUST00000048698(transcript)|ensembl:ENSMUST00000110936(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_033341.1|refseq:XP_017176274.1|refseq:XP_017176275.1|dip:DIP-493N|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0071339"(MLL1 complex)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|mint:Q62311|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:mtSdd0697PTHLPB/W7Ejs9Yxlsg10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8C092	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-12667248|uniprotkb:Q8BTR2	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:taf5_mouse(display_long)|uniprotkb:Taf5(gene name)|psi-mi:Taf5(display_short)|uniprotkb:Transcription initiation factor TFIID 100 kDa subunit(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_796316.2|interpro:IPR020472|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|interpro:IPR037783|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037264	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:iDpKf85r1pKLAdwDOwZtaDaePHs10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:G5E8Z2	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-12688342	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:taf4b_mouse(display_long)|uniprotkb:Taf4b(gene name)|psi-mi:Taf4b(display_short)|uniprotkb:Taf2c2(gene name synonym)|uniprotkb:Tafii105(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 105 kDa subunit(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007283"(spermatogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:2000648"(positive regulation of stem cell proliferation)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|interpro:IPR009072(Histone-fold)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR037249|refseq:NP_001093919.1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:CsJl9QaF7Z+6ay6IiiuYipru7hk10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8C176	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-12667225|uniprotkb:Q8BKQ7	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:taf2_mouse(display_long)|uniprotkb:Taf2(gene name)|psi-mi:Taf2(display_short)|uniprotkb:TBP-associated factor 150 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 150 kDa subunit(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	interpro:IPR016024(Armadillo-type fold)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0033276"(transcription factor TFTC complex)|interpro:IPR027268|interpro:IPR042097|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|interpro:IPR037813	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:GnJpi2osti9jjOha3ZZHeej94hc10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q920B9	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-2549823|uniprotkb:Q3TZ48|uniprotkb:Q3UFH0|uniprotkb:Q921H4	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:sp16h_mouse(display_long)|uniprotkb:Supt16h(gene name)|psi-mi:Supt16h(display_short)|uniprotkb:Fact140(gene name synonym)|uniprotkb:Factp140(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:Supt16(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|interpro:IPR029148|reactome:R-MMU-6804756|reactome:R-MMU-75955|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|refseq:NP_291096.2|dip:DIP-55972N|mint:Q920B9	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:qcl0ckY0w3tIem/ezLyPtHVUnZA10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q08943	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-2657613|uniprotkb:Q3U9Z2|uniprotkb:Q3UJ75|uniprotkb:Q4V9U4|uniprotkb:Q8CGA6|ensembl:ENSMUSP00000076971|ensembl:ENSMUSP00000127058	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:ssrp1_mouse(display_long)|uniprotkb:Ssrp1(gene name)|psi-mi:Ssrp1(display_short)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001129553.1|refseq:NP_892035.2|refseq:XP_006499133.1|ensembl:ENSMUSG00000027067(gene)|ensembl:ENSMUST00000077798(transcript)|ensembl:ENSMUST00000168266(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08943|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6804756|reactome:R-MMU-75955	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:QLbUR9V6OGtMwfD2fiZy4wEJwWE10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q9CSN1	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-2551848	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:snw1_mouse(display_long)|uniprotkb:Skiip(gene name synonym)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Snw1(gene name)|psi-mi:Snw1(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|reactome:R-MMU-2122947|reactome:R-MMU-2173796|reactome:R-MMU-350054|reactome:R-MMU-72163|reactome:R-MMU-8941856|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|refseq:NP_079783.2|dip:DIP-42051N|mint:Q9CSN1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:WKh+5sKG7RoxwHBF/GzueCqA4j410090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q91ZW3	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-927547|uniprotkb:Q8C791|uniprotkb:Q8CA22|uniprotkb:Q8VDG1|uniprotkb:Q925M9|ensembl:ENSMUSP00000044361	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:smca5_mouse(display_long)|uniprotkb:Smarca5(gene name)|psi-mi:Smarca5(display_short)|uniprotkb:Snf2h(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_444354.2|dip:DIP-36073N|ensembl:ENSMUSG00000031715(gene)|ensembl:ENSMUST00000043359(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:Q91ZW3|reactome:R-MMU-5250924|reactome:R-MMU-5693565|reactome:R-MMU-606279	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:+HXPfdDGqKssFXooxGP7gM+u8Oc10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q9WTM5	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-2549911|ensembl:ENSMUSP00000103400|ensembl:ENSMUSP00000147502	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:ruvb2_mouse(display_long)|uniprotkb:Ruvbl2(gene name)|psi-mi:Ruvbl2(display_short)|uniprotkb:p47 protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000003868(gene)|ensembl:ENSMUST00000107771(transcript)|ensembl:ENSMUST00000211214(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051117"(ATPase binding)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9WTM5|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_035434.1|refseq:XP_006540785.1|refseq:XP_006540786.1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:tHnjngaz5qWy9sPXagFLp3TRDtA10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8BX09	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-1556543|uniprotkb:Q3TBL4|uniprotkb:Q6PAP0|uniprotkb:Q6PFC2|uniprotkb:Q3U3G1|ensembl:ENSMUSP00000141003	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:rbbp5_mouse(display_long)|uniprotkb:Rbbp5(gene name)|psi-mi:Rbbp5(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_766105.2|dip:DIP-61809N|ensembl:ENSMUSG00000026439(gene)|ensembl:ENSMUST00000190997(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q8BX09|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-201722|reactome:R-MMU-3214841|reactome:R-MMU-8936459|reactome:R-MMU-8951664|go:"GO:0035097"(histone methyltransferase complex)	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:IfmUqzNWpYZzHDMDGeLiZqEcRK010090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q60972	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-302291|uniprotkb:A2A875|ensembl:ENSMUSP00000099658	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:rbbp4_mouse(display_long)|uniprotkb:Rbbp4(gene name)|psi-mi:Rbbp4(display_short)|uniprotkb:Rbap48(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000057236(gene)|ensembl:ENSMUST00000102598(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q60972|reactome:R-MMU-1538133|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-606279|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-8953750|refseq:NP_033056.2|dip:DIP-32855N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q91YR7	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-6876849|ensembl:ENSMUSP00000002529|ensembl:ENSMUSP00000121340|uniprotkb:Q3ULJ7|uniprotkb:Q542P0|uniprotkb:Q8CIK9|uniprotkb:Q8R3M8|uniprotkb:Q99JN1|uniprotkb:Q9CSZ0	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:prp6_mouse(display_long)|uniprotkb:Prpf6(gene name)|psi-mi:Prpf6(display_short)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000002455(gene)|ensembl:ENSMUST00000002529(transcript)|ensembl:ENSMUST00000136481(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:Q91YR7|rcsb pdb:6QX9|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_598462.1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:dxGQPYKGfgDyylKz6TISBJfMIBs10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q9DBD5	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-6909114|ensembl:ENSMUSP00000019065|uniprotkb:Q5F2E2|uniprotkb:Q6PEM0|uniprotkb:Q91YM9	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:pelp1_mouse(display_long)|uniprotkb:Pelp1(gene name)|psi-mi:Pelp1(display_short)|uniprotkb:Mnar(gene name synonym)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR012980(Protein of unknown function NUC202)|interpro:IPR016024(Armadillo-type fold)|mint:Q9DBD5|reactome:R-MMU-6791226|go:"GO:0035327"|ensembl:ENSMUSG00000018921(gene)|ensembl:ENSMUST00000019065(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:NP_083507.3	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:ekcHE9INQnzjdsJTuE6+3e1R+Fs10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:P11103	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:P09405	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-641864|uniprotkb:Q548M9|uniprotkb:Q61991|uniprotkb:Q8BQD8|uniprotkb:Q99K50|ensembl:ENSMUSP00000027438	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:nucl_mouse(display_long)|uniprotkb:Protein C23(gene name synonym)|uniprotkb:Ncl(gene name)|psi-mi:Ncl(display_short)|uniprotkb:Nuc(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_035010.3|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990631"(ErbB-4 class receptor binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000232"(regulation of rRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P09405|reactome:R-MMU-6791226|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000026234(gene)|ensembl:ENSMUST00000027438(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:NkPifysnX6CafgtN+Ko/p4aBqGE10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q7TPV4	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-1373622|uniprotkb:O35851|uniprotkb:Q80Y66|uniprotkb:Q8R4X2|uniprotkb:Q99KP0|ensembl:ENSMUSP00000044827	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:mbb1a_mouse(display_long)|uniprotkb:Mybbp1a(gene name)|psi-mi:Mybbp1a(display_short)|uniprotkb:P160(gene name synonym)|uniprotkb:Myb-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_058056.2|dip:DIP-39831N|ensembl:ENSMUSG00000040463(gene)|ensembl:ENSMUST00000045633(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR016024(Armadillo-type fold)|mint:Q7TPV4|reactome:R-MMU-5250924	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:rt1TQLZB7JNBkpt3DooDAlzOYCo10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8K4B0	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-1216353|uniprotkb:Q80UI1|uniprotkb:Q8K4D4|uniprotkb:Q924K9|ensembl:ENSMUSP00000009099	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:mta1_mouse(display_long)|uniprotkb:Mta1(gene name)|psi-mi:Mta1(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:XP_006515485.1|dip:DIP-38226N|ensembl:ENSMUSG00000021144(gene)|ensembl:ENSMUST00000009099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|reactome:R-MMU-3214815|reactome:R-MMU-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033363"(secretory granule organization)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q8K4B0|reactome:R-MMU-73762|reactome:R-MMU-8943724	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:5DvgpUkohteacGjUvdFq7C+fU2w10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q9Z2D6	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-1188816|uniprotkb:Q3TYG1|uniprotkb:B1AUZ2|uniprotkb:B1AUZ3|ensembl:ENSMUSP00000098314|ensembl:ENSMUSP00000127115	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:mecp2_mouse(display_long)|uniprotkb:Mecp2(gene name)|psi-mi:Mecp2(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001075448.1|refseq:NP_034918.1|ensembl:ENSMUSG00000031393(gene)|ensembl:ENSMUST00000100750(transcript)|ensembl:ENSMUST00000170481(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042220"(response to cocaine)|go:"GO:0042551"(neuron maturation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071317"(cellular response to isoquinoline alkaloid)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1901956"(positive regulation of retrograde dense core granule transport)|go:"GO:1903860"(negative regulation of dendrite extension)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905492"(positive regulation of branching morphogenesis of a nerve)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:Q9Z2D6|rcsb pdb:5NAF|reactome:R-MMU-9022692|go:"GO:0010385"(double-stranded methylated DNA binding)|dip:DIP-39984N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:+kDY0EPkyG+tTLMlP0zZFOS1R3E10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q05CL8	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-6260966|ensembl:ENSMUSP00000029588|uniprotkb:Q8VDW3|uniprotkb:Q9CUQ5|uniprotkb:Q3TSC2|uniprotkb:Q9CSI9|uniprotkb:Q8K2Y6|uniprotkb:Q9CSI2	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:larp7_mouse(display_long)|uniprotkb:D3Wsu161e(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:Larp7(gene name)|psi-mi:Larp7(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000027968(gene)|ensembl:ENSMUST00000029588(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q05CL8|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_613059.2	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:LXPfM/sQrPvcSwU7ti5T93JQ6+k10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:O55222	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-6690138|uniprotkb:Q78KK2|ensembl:ENSMUSP00000033182|ensembl:ENSMUSP00000130341	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:ilk_mouse(display_long)|uniprotkb:59 kDa serine/threonine-protein kinase(gene name synonym)|uniprotkb:Beta-integrin-linked kinase(gene name synonym)|uniprotkb:ILK-1(gene name synonym)|uniprotkb:ILK-2(gene name synonym)|uniprotkb:ILK1(gene name synonym)|uniprotkb:ILK2(gene name synonym)|uniprotkb:p59ILK(gene name synonym)|uniprotkb:Ilk(gene name)|psi-mi:Ilk(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001155196.1|refseq:NP_034692.2|ensembl:ENSMUSG00000030890(gene)|ensembl:ENSMUST00000033182(transcript)|ensembl:ENSMUST00000163389(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032288"(myelin assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043034"(costamere)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR035692|interpro:IPR036770|mint:O55222|reactome:R-MMU-446343|reactome:R-MMU-446353|dip:DIP-41971N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:9kMagkwUrtq1XaI+9PXPJ21hHY810090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:P70288	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-302251|uniprotkb:B2RRP3	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:bGLIDKTlyhBz40NViC8calRacZ010090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8VHR5	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-3043880|ensembl:ENSMUSP00000041370|ensembl:ENSMUSP00000142514|ensembl:ENSMUSP00000142617|uniprotkb:Q8C9Q3	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:p66b_mouse(display_long)|uniprotkb:Gatad2b(gene name)|psi-mi:Gatad2b(display_short)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)|uniprotkb:p66/p68(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000042390(gene)|ensembl:ENSMUST00000049382(transcript)|ensembl:ENSMUST00000199607(transcript)|ensembl:ENSMUST00000199754(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|mint:Q8VHR5|refseq:XP_006501422.2|refseq:NP_647465.1|refseq:XP_006501424.1|dip:DIP-62049N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:u6tGN+nqNC/bn1hYG7e1f3XGgj010090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8CHY6	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-3043877|ensembl:ENSMUSP00000112164|ensembl:ENSMUSP00000148474|uniprotkb:Q8BTQ2|uniprotkb:Q8VEC9	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:p66a_mouse(display_long)|uniprotkb:Gatad2a(gene name)|psi-mi:Gatad2a(display_short)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000036180(gene)|ensembl:ENSMUST00000116463(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001842"(neural fold formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0012501"(programmed cell death)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0021506"(anterior neuropore closure)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR032346|interpro:IPR040386|mint:Q8CHY6|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|ensembl:ENSMUST00000212478(transcript)|refseq:XP_011240597.1|refseq:NP_001106817.1	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:Sl8kjbcfcvx+CKED3wLD9HvAEjs10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q91VC3	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-2552399|ensembl:ENSMUSP00000026667|uniprotkb:Q3UD29|uniprotkb:Q3TEZ8|uniprotkb:B2RY38|uniprotkb:Q8BVY3	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:if4a3_mouse(display_long)|uniprotkb:Eif4a3(gene name)|psi-mi:Eif4a3(display_short)|uniprotkb:Ddx48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	reactome:R-MMU-975957|ensembl:ENSMUSG00000025580(gene)|ensembl:ENSMUST00000026667(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|refseq:NP_619610.1|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q91VC3|reactome:R-MMU-1169408|reactome:R-MMU-159236|reactome:R-MMU-429947|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:6jjMHbLWWbe2j3Qv+g8b/PbY7Ps10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:P30999	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-529924|uniprotkb:Q3TSU9|uniprotkb:Q80XQ4|uniprotkb:Q8CHF8|ensembl:ENSMUSP00000064518|ensembl:ENSMUSP00000107320|ensembl:ENSMUSP00000141166	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:ctnd1_mouse(display_long)|uniprotkb:Kiaa0384(gene name synonym)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:Ctnnd1(gene name)|psi-mi:Ctnnd1(display_short)|uniprotkb:Catns(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001078917.1|refseq:NP_001078918.1|refseq:NP_001078919.1|refseq:NP_001078922.1|refseq:NP_031641.2|refseq:XP_006498698.1|refseq:XP_017170690.1|refseq:XP_017170697.1|dip:DIP-31972N|ensembl:ENSMUSG00000034101(gene)|ensembl:ENSMUSG00000101645(gene)|ensembl:ENSMUST00000067232(transcript)|ensembl:ENSMUST00000111691(transcript)|ensembl:ENSMUST00000189772(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001822"(kidney development)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060690"(epithelial cell differentiation involved in salivary gland development)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:P30999|reactome:R-MMU-418990|reactome:R-MMU-5218920	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:CvcAbgejB5iLlsSAxt47G/6W3P410090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q61164	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-932785|ensembl:ENSMUSP00000005841	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q60737	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q6PDQ2	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-3043852|ensembl:ENSMUSP00000060054	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q99J95	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q6A068	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-2552123|ensembl:ENSMUSP00000024727|uniprotkb:Q8K1J9	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:cdc5l_mouse(display_long)|uniprotkb:Cdc5l(gene name)|psi-mi:Cdc5l(display_short)|uniprotkb:Kiaa0432(gene name synonym)|uniprotkb:Cdc5-like protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000023932(gene)|ensembl:ENSMUST00000024727(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|refseq:NP_690023.1|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q6A068|reactome:R-MMU-72163|go:"GO:0005737"(cytoplasm)	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:ehcu1kQlVD4/J1K3a77EcsjqRbI10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q8CH18	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-645246|uniprotkb:Q6AXC9|uniprotkb:Q6PAR2|uniprotkb:Q80XE4|uniprotkb:Q8BJY0|uniprotkb:Q8BVN2|uniprotkb:Q8CGG1|uniprotkb:Q9CSR5|uniprotkb:Q05BR1|uniprotkb:Q05DK6|ensembl:ENSMUSP00000020268|ensembl:ENSMUSP00000151895	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:ccar1_mouse(display_long)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Ccar1(gene name)|psi-mi:Ccar1(display_short)|uniprotkb:Carp1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_080477.1|refseq:XP_006514057.1|refseq:XP_006514058.1|refseq:XP_006514059.1|refseq:XP_006514060.1|refseq:XP_011241839.1|ensembl:ENSMUSG00000020074(gene)|ensembl:ENSMUST00000020268(transcript)|ensembl:ENSMUST00000219527(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8CH18|reactome:R-MMU-72163	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:fipMhp0uguP4AXVte036ScUyq5g10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q9Z2N8	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-2942759|ensembl:ENSMUSP00000029214|uniprotkb:Q8C1W3|uniprotkb:Q99M56	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:acl6a_mouse(display_long)|uniprotkb:Actl6a(gene name)|psi-mi:Actl6a(display_short)|uniprotkb:Actl6(gene name synonym)|uniprotkb:Baf53a(gene name synonym)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16360068|imex:IM-26212-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSMUSG00000027671(gene)|ensembl:ENSMUST00000029214(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:Q9Z2N8|reactome:R-MMU-3214858|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8939243|go:"GO:0007399"(nervous system development)|refseq:NP_062647.2	go:"GO:0005634"(nucleus)	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Table S1 and figure 1E|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2017/08/16	2018/10/12	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:a0spTksUhZbdXCOGGaNvsL997Vk10090	rigid:M67LolXQoF4DaJBNZEKwJf8poko	false	tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P70326	uniprotkb:Q14839	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16361553|imex:IM-26212-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N	-	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Figure 5 C & D|comment:TBX5 Interaction with CHD4 Does Not Require Either the CHD4 Chromo Domains or the Phd Domains|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/08/16	2017/08/16	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	rigid:0txTPXqTCfzcSEXVmkQwj44ULaI	false	tag:c-c|v5 tag:c-c	green fluorescent protein tag:n-n|binding-associated region:1-758	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P70326	uniprotkb:Q14839	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16365383|imex:IM-26212-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N	-	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Figure 5 K|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/08/16	2017/08/24	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	rigid:KOrW9AMSVcj3r7i0ospHtV3jGxc	false	mutation disrupting interaction strength:266-266|mutation disrupting interaction strength:292-292|mutation disrupting interaction strength:252-252|mutation disrupting interaction strength:261-261|v5 tag:c-c|mutation disrupting interaction strength:263-263	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70326	uniprotkb:Q13330	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-714236|uniprotkb:Q8NFI8|uniprotkb:Q96GI8|uniprotkb:A5PLK4|intact:EBI-28976623|ensembl:ENSP00000333633|uniprotkb:Q86SW2	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:mta1_human(display_long)|uniprotkb:MTA1(gene name)|psi-mi:MTA1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16365383|imex:IM-26212-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	refseq:NP_001190187.1|refseq:NP_004680.2|ensembl:ENSP00000333633|ensembl:ENST00000405646|ensembl:ENSP00000384180|ensembl:ENST00000438610|ensembl:ENSP00000393438|ensembl:ENSG00000182979(gene)|ensembl:ENST00000331320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q13330|rcsb pdb:4BKX|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:5FXY|rcsb pdb:5ICN|rcsb pdb:6G16|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AO8|go:"GO:0045475"(locomotor rhythm)|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-3214815|dip:DIP-41751N	-	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Figure 5 K|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/08/16	2017/08/24	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:nDDSb5B6YCbq5/6qvgtnUWtP23M9606	rigid:KOrW9AMSVcj3r7i0ospHtV3jGxc	false	mutation disrupting interaction strength:266-266|mutation disrupting interaction strength:292-292|mutation disrupting interaction strength:252-252|mutation disrupting interaction strength:261-261|v5 tag:c-c|mutation disrupting interaction strength:263-263	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70326	uniprotkb:Q14839	intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short)	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16365805|imex:IM-26212-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N	-	function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint	-	figure legend:Figure 5 E & F|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/08/16	2017/08/22	rogid:i1XrRIxNM++VvPUapK4t789c+f410090	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	rigid:0txTPXqTCfzcSEXVmkQwj44ULaI	false	sufficient binding region:238-340|tag:c-c|v5 tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
ensembl:ENSMUSG00000051401	uniprotkb:Q14839	intact:EBI-16394216	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	uniprotkb:Kctd16(gene name)|psi-mi:Kctd16(display_short)|uniprotkb:Gm1267(gene name synonym)|uniprotkb:Kiaa1317(gene name synonym)|ensembl:kcd16_mouse_gene(shortlabel)|psi-mi:ENSMUSG00000051401(display_long)	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Waldron et al. (2016)	pubmed:26859351|imex:IM-26212	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-16394202|imex:IM-26212-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_080411.1|refseq:XP_017173425.1|refseq:XP_017173426.1|refseq:XP_017173427.1|refseq:XP_017173428.1	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N	-	-	-	figure legend:Figure 5 E & F|comment:in presence of TBX5 where TBX5 acts as a repressor of Kctd16 transcription|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/08/16	2017/08/24	-	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	-	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)