#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32639 uniprotkb:Q06819 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484 psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194589|imex:IM-25357-1|dip:DIP-200938E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:B8C11278571C57E5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292 rigid:19jpuQYrNX6yP2O+kslW3DsiAGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P49704 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-347|uniprotkb:Q66R99|uniprotkb:D6VUM3|ensemblfungi:YGR091W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp31_yeast(display_long)|uniprotkb:PRP31(gene name)|psi-mi:PRP31(display_short)|uniprotkb:YGR091W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194589|imex:IM-25357-1|dip:DIP-200938E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_011605.1|sgd:S000003323|dip:DIP-5355N|mint:P49704|ensemblfungi:YGR091W(gene)|ensemblfungi:YGR091W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005739"(mitochondrion)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012976(NOSIC)|interpro:IPR019175|interpro:IPR027105|interpro:IPR036070|interpro:IPR042239|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:E39AC6247859FB3B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:H41JrfockxRzf+U5GKVgGxBTrW0559292 rigid:19jpuQYrNX6yP2O+kslW3DsiAGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q03338 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194589|imex:IM-25357-1|dip:DIP-200938E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:E977FD9F708BDD91 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292 rigid:19jpuQYrNX6yP2O+kslW3DsiAGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P20053 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194589|imex:IM-25357-1|dip:DIP-200938E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:7CCCA3A92AC0CE78 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292 rigid:19jpuQYrNX6yP2O+kslW3DsiAGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P19735 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-227|uniprotkb:D6VQ54|ensemblfungi:YBR055C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp6_yeast(display_long)|uniprotkb:PRP6(gene name)|psi-mi:PRP6(display_short)|uniprotkb:RNA6(gene name synonym)|uniprotkb:YBR055C(locus name)|uniprotkb:YBR0508(orf name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194589|imex:IM-25357-1|dip:DIP-200938E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_009611.1|sgd:S000000259|mint:P19735|dip:DIP-1290N|ensemblfungi:YBR055C(gene)|ensemblfungi:YBR055C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071001"(U4/U6 snRNP)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:3E87F8AF63EAAC41 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:v3xgQmlk5z/P4uu09sipcLZmlpE559292 rigid:19jpuQYrNX6yP2O+kslW3DsiAGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P33334 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194589|imex:IM-25357-1|dip:DIP-200938E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:8F4F6F89D34D3508 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rigid:19jpuQYrNX6yP2O+kslW3DsiAGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P39990 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2 psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194589|imex:IM-25357-1|dip:DIP-200938E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:4489780153E8F182 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292 rigid:19jpuQYrNX6yP2O+kslW3DsiAGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P33334 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:8F4F6F89D34D3508 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P40018 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-432|uniprotkb:D3DLS8|ensemblfungi:YER029C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:rsmb_yeast(display_long)|uniprotkb:SMB1(gene name)|psi-mi:SMB1(display_short)|uniprotkb:Sm protein B(gene name synonym)|uniprotkb:YER029C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000000831|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YER029C(gene)|ensemblfungi:YER029C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|refseq:NP_010946.3|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|dip:DIP-843N|mint:P40018 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:0A1078D5AA241430 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:b62+dBOdvQgeE0oup4kbXbviS1U559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q12330 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:B76D72DA8456F3B5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P54999 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-770|uniprotkb:D6W4I2|ensemblfungi:YPR182W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:ruxf_yeast(display_long)|uniprotkb:SMX3(gene name)|psi-mi:SMX3(display_short)|uniprotkb:YPR182W(locus name)|uniprotkb:P9705.4(orf name)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_015508.1|sgd:S000006386|dip:DIP-1634N|mint:P54999|ensemblfungi:YPR182W(gene)|ensemblfungi:YPR182W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|rcsb pdb:1N9R|rcsb pdb:1N9S|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:1640D3237597B2D8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:iyBbVNf2fgOIqhnOg9Etn3P2r3Q559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P40204 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-637|uniprotkb:D6VTL2|ensemblfungi:YFL017W-A psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:ruxg_yeast(display_long)|uniprotkb:SNP2(gene name synonym)|uniprotkb:YFL017Bw(orf name)|uniprotkb:YFL017W-A(locus name)|uniprotkb:SMX2(gene name)|psi-mi:SMX2(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_116636.1|sgd:S000002965|dip:DIP-6683N|mint:P40204|ensemblfungi:YFL017W-A(gene)|ensemblfungi:YFL017W-A_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|rcsb pdb:7DCO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:5C6208B8C5A9AB33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:Wh37rGoSJFpJ5o+CuNkBnpiu/5s559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q02260 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-585|uniprotkb:D6VUK6|ensemblfungi:YGR074W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:smd1_yeast(display_long)|uniprotkb:YGR074W(locus name)|uniprotkb:SMD1(gene name)|psi-mi:SMD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000003306|refseq:NP_011588.3|dip:DIP-227N|mint:Q02260|ensemblfungi:YGR074W(gene)|ensemblfungi:YGR074W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:9929F21EB9218447 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:SvOKDbY05xgJXKZ8uS+keXsC41I559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q06217 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-235|uniprotkb:D6VYS2|ensemblfungi:YLR275W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:smd2_yeast(display_long)|uniprotkb:SMD2(gene name)|psi-mi:SMD2(display_short)|uniprotkb:YLR275W(locus name)|uniprotkb:L9328.5(orf name)|uniprotkb:snRNP core protein D2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000004265|refseq:NP_013377.1|mint:Q06217|dip:DIP-1421N|ensemblfungi:YLR275W(gene)|ensemblfungi:YLR275W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:7287070B10E090C0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:rglZ3AQuJfa1rFYIeZLqiYj+L4U559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P43321 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-529|ensemblfungi:YLR147C|uniprotkb:D6VYE2|uniprotkb:E9P8W3 psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:smd3_yeast(display_long)|uniprotkb:SMD3(gene name)|psi-mi:SMD3(display_short)|uniprotkb:YLR147C(locus name)|uniprotkb:L9634.6(orf name)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_013248.1|sgd:S000004137|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YLR147C(gene)|ensemblfungi:YLR147C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|dip:DIP-715N|mint:P43321 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:BB02A56C5AD70CF2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:ueJ4D76t8ilvz/p9qMzIGiCzqWk559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q12420 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-260|uniprotkb:D6W308|ensemblfungi:YOR308C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:snu66_yeast(display_long)|uniprotkb:SNU66(gene name)|psi-mi:SNU66(display_short)|uniprotkb:05667(orf name)|uniprotkb:YOR308C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194613|imex:IM-25357-2|dip:DIP-200939E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000005835|refseq:NP_014953.3|mint:Q12420|dip:DIP-5216N|ensemblfungi:YOR308C(gene)|ensemblfungi:YOR308C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR005011(SART-1 protein)|rcsb pdb:3PLU|rcsb pdb:3PLV|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:154BC3873DD6B0FA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:+h6+o43YeiJlMZ1bVF45QdZ8Y00559292 rigid:j4N1v9Bivulxa31DjuekaNWqdMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q06819 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484 psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:B8C11278571C57E5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P38203 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4 psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:C23856268CEE92E2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:3E5c7Mzg433awFPmamamsKjtJmY559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P57743 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-10227|uniprotkb:Q05176|uniprotkb:Q06759|uniprotkb:D6VZ73|ensemblfungi:YLR438C-A psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:lsm3_yeast(display_long)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)|uniprotkb:SMX4(gene name synonym)|uniprotkb:USS2(gene name synonym)|uniprotkb:YLR438C-A(locus name)|uniprotkb:SmX4 protein(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000006434|ensemblfungi:YLR438C-A(gene)|ensemblfungi:YLR438C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|rcsb pdb:3BW1|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|rcsb pdb:4M75|refseq:NP_013543.3|dip:DIP-2587N|mint:P57743 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:787084EF6A5945B7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:nYl7At1SnlSwN+nWr1F1xm0tdDE559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P40070 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:69CAC1F01D5BFA98 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P40089 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-10236|uniprotkb:D3DM53|ensemblfungi:YER146W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:lsm5_yeast(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short)|uniprotkb:YER146W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_011073.1|sgd:S000000948|ensemblfungi:YER146W(gene)|ensemblfungi:YER146W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|rcsb pdb:4C8Q|rcsb pdb:3JCM|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|dip:DIP-1417N|mint:P40089 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:84E8A1E8E2F078FE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:+Q2uxsm6FVpx5lehw62szhlGh8U559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q06406 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-196|uniprotkb:D6VT10|ensemblfungi:YDR378C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:lsm6_yeast(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short)|uniprotkb:D9481.18(orf name)|uniprotkb:YDR378C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_010666.2|sgd:S000002786|mint:Q06406|dip:DIP-1418N|ensemblfungi:YDR378C(gene)|ensemblfungi:YDR378C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0008033"(tRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:74FE40A4509CEF33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:JQtrhOkngO6APIPCFMRnKogB96c559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P53905 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-141|uniprotkb:D6W135|ensemblfungi:YNL147W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:lsm7_yeast(display_long)|uniprotkb:LSM7(gene name)|psi-mi:LSM7(display_short)|uniprotkb:N1202(orf name)|uniprotkb:N1780(orf name)|uniprotkb:YNL147W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_014252.2|sgd:S000005091|mint:P53905|dip:DIP-1419N|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|ensemblfungi:YNL147W(gene)|ensemblfungi:YNL147W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0008033"(tRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017132(U6 snRNA-associated Sm-like protein LSm7)|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:EA1D019FC5D1B5C5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:LBD0KzUVuBCAGeCVPV5bSS8Hodg559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P47093 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-313|uniprotkb:D6VWJ6|ensemblfungi:YJR022W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:lsm8_yeast(display_long)|uniprotkb:LSM8(gene name)|psi-mi:LSM8(display_short)|uniprotkb:J1464(orf name)|uniprotkb:YJR83.16(orf name)|uniprotkb:YJR022W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_012556.2|sgd:S000003783|ensemblfungi:YJR022W(gene)|ensemblfungi:YJR022W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034103|interpro:IPR044642|dip:DIP-903N|rcsb pdb:3JCM|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|mint:P47093 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:B6E37F585B6292EA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:+X6fjvb8flf36BcPKxtclUwNMSY559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P49704 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-347|uniprotkb:Q66R99|uniprotkb:D6VUM3|ensemblfungi:YGR091W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp31_yeast(display_long)|uniprotkb:PRP31(gene name)|psi-mi:PRP31(display_short)|uniprotkb:YGR091W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_011605.1|sgd:S000003323|dip:DIP-5355N|mint:P49704|ensemblfungi:YGR091W(gene)|ensemblfungi:YGR091W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005739"(mitochondrion)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012976(NOSIC)|interpro:IPR019175|interpro:IPR027105|interpro:IPR036070|interpro:IPR042239|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:E39AC6247859FB3B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:H41JrfockxRzf+U5GKVgGxBTrW0559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q03338 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:E977FD9F708BDD91 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P20053 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:7CCCA3A92AC0CE78 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P19735 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-227|uniprotkb:D6VQ54|ensemblfungi:YBR055C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp6_yeast(display_long)|uniprotkb:PRP6(gene name)|psi-mi:PRP6(display_short)|uniprotkb:RNA6(gene name synonym)|uniprotkb:YBR055C(locus name)|uniprotkb:YBR0508(orf name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_009611.1|sgd:S000000259|mint:P19735|dip:DIP-1290N|ensemblfungi:YBR055C(gene)|ensemblfungi:YBR055C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071001"(U4/U6 snRNP)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:3E87F8AF63EAAC41 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:v3xgQmlk5z/P4uu09sipcLZmlpE559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P33334 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:8F4F6F89D34D3508 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P40018 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-432|uniprotkb:D3DLS8|ensemblfungi:YER029C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:rsmb_yeast(display_long)|uniprotkb:SMB1(gene name)|psi-mi:SMB1(display_short)|uniprotkb:Sm protein B(gene name synonym)|uniprotkb:YER029C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000000831|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YER029C(gene)|ensemblfungi:YER029C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|refseq:NP_010946.3|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|dip:DIP-843N|mint:P40018 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:0A1078D5AA241430 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:b62+dBOdvQgeE0oup4kbXbviS1U559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q12330 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:B76D72DA8456F3B5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P54999 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-770|uniprotkb:D6W4I2|ensemblfungi:YPR182W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:ruxf_yeast(display_long)|uniprotkb:SMX3(gene name)|psi-mi:SMX3(display_short)|uniprotkb:YPR182W(locus name)|uniprotkb:P9705.4(orf name)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_015508.1|sgd:S000006386|dip:DIP-1634N|mint:P54999|ensemblfungi:YPR182W(gene)|ensemblfungi:YPR182W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|rcsb pdb:1N9R|rcsb pdb:1N9S|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:1640D3237597B2D8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:iyBbVNf2fgOIqhnOg9Etn3P2r3Q559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P40204 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-637|uniprotkb:D6VTL2|ensemblfungi:YFL017W-A psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:ruxg_yeast(display_long)|uniprotkb:SNP2(gene name synonym)|uniprotkb:YFL017Bw(orf name)|uniprotkb:YFL017W-A(locus name)|uniprotkb:SMX2(gene name)|psi-mi:SMX2(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_116636.1|sgd:S000002965|dip:DIP-6683N|mint:P40204|ensemblfungi:YFL017W-A(gene)|ensemblfungi:YFL017W-A_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|rcsb pdb:7DCO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:5C6208B8C5A9AB33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:Wh37rGoSJFpJ5o+CuNkBnpiu/5s559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q02260 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-585|uniprotkb:D6VUK6|ensemblfungi:YGR074W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:smd1_yeast(display_long)|uniprotkb:YGR074W(locus name)|uniprotkb:SMD1(gene name)|psi-mi:SMD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000003306|refseq:NP_011588.3|dip:DIP-227N|mint:Q02260|ensemblfungi:YGR074W(gene)|ensemblfungi:YGR074W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:9929F21EB9218447 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:SvOKDbY05xgJXKZ8uS+keXsC41I559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q06217 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-235|uniprotkb:D6VYS2|ensemblfungi:YLR275W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:smd2_yeast(display_long)|uniprotkb:SMD2(gene name)|psi-mi:SMD2(display_short)|uniprotkb:YLR275W(locus name)|uniprotkb:L9328.5(orf name)|uniprotkb:snRNP core protein D2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000004265|refseq:NP_013377.1|mint:Q06217|dip:DIP-1421N|ensemblfungi:YLR275W(gene)|ensemblfungi:YLR275W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:7287070B10E090C0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:rglZ3AQuJfa1rFYIeZLqiYj+L4U559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P43321 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-529|ensemblfungi:YLR147C|uniprotkb:D6VYE2|uniprotkb:E9P8W3 psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:smd3_yeast(display_long)|uniprotkb:SMD3(gene name)|psi-mi:SMD3(display_short)|uniprotkb:YLR147C(locus name)|uniprotkb:L9634.6(orf name)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_013248.1|sgd:S000004137|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YLR147C(gene)|ensemblfungi:YLR147C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|dip:DIP-715N|mint:P43321 psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:BB02A56C5AD70CF2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:ueJ4D76t8ilvz/p9qMzIGiCzqWk559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P36048 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-243|uniprotkb:D6VX27|ensemblfungi:YKL173W psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:sn114_yeast(display_long)|uniprotkb:GIN10(gene name synonym)|uniprotkb:YKL173W(locus name)|uniprotkb:YKL637(orf name)|uniprotkb:SNU114(gene name)|psi-mi:SNU114(display_short)|uniprotkb:Growth inhibitory protein 10(gene name synonym)|uniprotkb:114 kDa U5 small nuclear ribonucleoprotein component(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V refseq:NP_012748.1|sgd:S000001656|mint:P36048|dip:DIP-759N|ensemblfungi:YKL173W(gene)|ensemblfungi:YKL173W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR044121|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:5CE30CEFF154D013 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:eHDUPadk87+Qb525xpL1tMWb3S4559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:P39990 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2 psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:4489780153E8F182 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32639 uniprotkb:Q12420 intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C intact:EBI-260|uniprotkb:D6W308|ensemblfungi:YOR308C psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym) psi-mi:snu66_yeast(display_long)|uniprotkb:SNU66(gene name)|psi-mi:SNU66(display_short)|uniprotkb:05667(orf name)|uniprotkb:YOR308C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194639|imex:IM-25357-3|dip:DIP-200937E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V sgd:S000005835|refseq:NP_014953.3|mint:Q12420|dip:DIP-5216N|ensemblfungi:YOR308C(gene)|ensemblfungi:YOR308C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR005011(SART-1 protein)|rcsb pdb:3PLU|rcsb pdb:3PLV|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO psi-mi:"MI:0465"(dip) crc64:DFAF7E3B7168D944 crc64:154BC3873DD6B0FA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292 rogid:+h6+o43YeiJlMZ1bVF45QdZ8Y00559292 rigid:iOLGa4TiRh3CbPX+84DjBj3XAmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33334 uniprotkb:P40018 intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C intact:EBI-432|uniprotkb:D3DLS8|ensemblfungi:YER029C psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:rsmb_yeast(display_long)|uniprotkb:SMB1(gene name)|psi-mi:SMB1(display_short)|uniprotkb:Sm protein B(gene name synonym)|uniprotkb:YER029C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194679|imex:IM-25357-4|dip:DIP-200940E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 sgd:S000000831|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YER029C(gene)|ensemblfungi:YER029C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|refseq:NP_010946.3|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|dip:DIP-843N|mint:P40018 psi-mi:"MI:0465"(dip) crc64:8F4F6F89D34D3508 crc64:0A1078D5AA241430 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rogid:b62+dBOdvQgeE0oup4kbXbviS1U559292 rigid:RJ8F/VLwJhODqSElPJv8iBGuIeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33334 uniprotkb:Q12330 intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194679|imex:IM-25357-4|dip:DIP-200940E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 psi-mi:"MI:0465"(dip) crc64:8F4F6F89D34D3508 crc64:B76D72DA8456F3B5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rigid:RJ8F/VLwJhODqSElPJv8iBGuIeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33334 uniprotkb:P54999 intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C intact:EBI-770|uniprotkb:D6W4I2|ensemblfungi:YPR182W psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:ruxf_yeast(display_long)|uniprotkb:SMX3(gene name)|psi-mi:SMX3(display_short)|uniprotkb:YPR182W(locus name)|uniprotkb:P9705.4(orf name)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194679|imex:IM-25357-4|dip:DIP-200940E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 refseq:NP_015508.1|sgd:S000006386|dip:DIP-1634N|mint:P54999|ensemblfungi:YPR182W(gene)|ensemblfungi:YPR182W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|rcsb pdb:1N9R|rcsb pdb:1N9S|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:8F4F6F89D34D3508 crc64:1640D3237597B2D8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rogid:iyBbVNf2fgOIqhnOg9Etn3P2r3Q559292 rigid:RJ8F/VLwJhODqSElPJv8iBGuIeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33334 uniprotkb:P40204 intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C intact:EBI-637|uniprotkb:D6VTL2|ensemblfungi:YFL017W-A psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:ruxg_yeast(display_long)|uniprotkb:SNP2(gene name synonym)|uniprotkb:YFL017Bw(orf name)|uniprotkb:YFL017W-A(locus name)|uniprotkb:SMX2(gene name)|psi-mi:SMX2(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194679|imex:IM-25357-4|dip:DIP-200940E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 refseq:NP_116636.1|sgd:S000002965|dip:DIP-6683N|mint:P40204|ensemblfungi:YFL017W-A(gene)|ensemblfungi:YFL017W-A_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|rcsb pdb:7DCO psi-mi:"MI:0465"(dip) crc64:8F4F6F89D34D3508 crc64:5C6208B8C5A9AB33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rogid:Wh37rGoSJFpJ5o+CuNkBnpiu/5s559292 rigid:RJ8F/VLwJhODqSElPJv8iBGuIeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33334 uniprotkb:Q02260 intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C intact:EBI-585|uniprotkb:D6VUK6|ensemblfungi:YGR074W psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:smd1_yeast(display_long)|uniprotkb:YGR074W(locus name)|uniprotkb:SMD1(gene name)|psi-mi:SMD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194679|imex:IM-25357-4|dip:DIP-200940E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 sgd:S000003306|refseq:NP_011588.3|dip:DIP-227N|mint:Q02260|ensemblfungi:YGR074W(gene)|ensemblfungi:YGR074W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:8F4F6F89D34D3508 crc64:9929F21EB9218447 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rogid:SvOKDbY05xgJXKZ8uS+keXsC41I559292 rigid:RJ8F/VLwJhODqSElPJv8iBGuIeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33334 uniprotkb:Q06217 intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C intact:EBI-235|uniprotkb:D6VYS2|ensemblfungi:YLR275W psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:smd2_yeast(display_long)|uniprotkb:SMD2(gene name)|psi-mi:SMD2(display_short)|uniprotkb:YLR275W(locus name)|uniprotkb:L9328.5(orf name)|uniprotkb:snRNP core protein D2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194679|imex:IM-25357-4|dip:DIP-200940E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 sgd:S000004265|refseq:NP_013377.1|mint:Q06217|dip:DIP-1421N|ensemblfungi:YLR275W(gene)|ensemblfungi:YLR275W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V psi-mi:"MI:0465"(dip) crc64:8F4F6F89D34D3508 crc64:7287070B10E090C0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rogid:rglZ3AQuJfa1rFYIeZLqiYj+L4U559292 rigid:RJ8F/VLwJhODqSElPJv8iBGuIeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33334 uniprotkb:P43321 intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C intact:EBI-529|ensemblfungi:YLR147C|uniprotkb:D6VYE2|uniprotkb:E9P8W3 psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:smd3_yeast(display_long)|uniprotkb:SMD3(gene name)|psi-mi:SMD3(display_short)|uniprotkb:YLR147C(locus name)|uniprotkb:L9634.6(orf name)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194679|imex:IM-25357-4|dip:DIP-200940E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 refseq:NP_013248.1|sgd:S000004137|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YLR147C(gene)|ensemblfungi:YLR147C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|dip:DIP-715N|mint:P43321 psi-mi:"MI:0465"(dip) crc64:8F4F6F89D34D3508 crc64:BB02A56C5AD70CF2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rogid:ueJ4D76t8ilvz/p9qMzIGiCzqWk559292 rigid:RJ8F/VLwJhODqSElPJv8iBGuIeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33334 uniprotkb:P36048 intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C intact:EBI-243|uniprotkb:D6VX27|ensemblfungi:YKL173W psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name) psi-mi:sn114_yeast(display_long)|uniprotkb:GIN10(gene name synonym)|uniprotkb:YKL173W(locus name)|uniprotkb:YKL637(orf name)|uniprotkb:SNU114(gene name)|psi-mi:SNU114(display_short)|uniprotkb:Growth inhibitory protein 10(gene name synonym)|uniprotkb:114 kDa U5 small nuclear ribonucleoprotein component(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nguyen et al. (2016) pubmed:26829225|doi:10.1038/nature16940|imex:IM-25357 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16194679|imex:IM-25357-4|dip:DIP-200940E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334 refseq:NP_012748.1|sgd:S000001656|mint:P36048|dip:DIP-759N|ensemblfungi:YKL173W(gene)|ensemblfungi:YKL173W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR044121|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO psi-mi:"MI:0465"(dip) crc64:8F4F6F89D34D3508 crc64:5CE30CEFF154D013 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292 rogid:eHDUPadk87+Qb525xpL1tMWb3S4559292 rigid:RJ8F/VLwJhODqSElPJv8iBGuIeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)