#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A5PJW8 uniprotkb:O00267 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16192939|imex:IM-25349-1|dip:DIP-200910E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:OrFW+/scuuCt5ceccSPxjDBMadA false crosslinked residues:820-820 crosslinked residues:331-331 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3MZY8 uniprotkb:A5PJW8 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16192960|imex:IM-25349-2|dip:DIP-197747E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rigid:KchVjbTjHHLMUGIEZFe6NqHm0OU false crosslinked residues:331-331 crosslinked residues:458-458|crosslinked residues:815-815 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:F2Z4H3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586976|ensembl:ENSBTAP00000000606 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:f2z4h3_bovin(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000040199(gene)|ensembl:ENSBTAT00000000606(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001178994.1|dip:DIP-61193N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:G3MZY8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q1JQ91 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586829|ensembl:ENSBTAP00000072181 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:q1jq91_bovin(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000053244(gene)|ensembl:ENSBTAT00000074897(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001069926.1|dip:DIP-61189N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:2OiGCsqaQg5B+ERFRGHuJ0lDWhk9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q2T9T3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586877 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab1_bovin(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001033182.1|dip:DIP-61190N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:Mx5kGREtLV+ucw052BfPrTF6RlM9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32PE0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586902 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab2_bovin(display_long)|uniprotkb:POLR2F(gene name)|psi-mi:POLR2F(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit F(gene name synonym)|uniprotkb:RPB6 homolog(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:5FLM|rcsb pdb:5OIK|dip:DIP-61191N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fkAqQM+e1h4/cY6430P7sKAPJ1c9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q3ZBC0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587125|ensembl:ENSBTAP00000030490 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab4_bovin(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000022539(gene)|ensembl:ENSBTAT00000030510(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|dip:DIP-61197N|refseq:NP_001032712.1|refseq:NP_001290464.1|refseq:NP_001290465.1|refseq:XP_015321795.1|refseq:XP_015329927.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P78 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587047|ensembl:ENSBTAP00000041501 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab5_bovin(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000031061(gene)|ensembl:ENSBTAT00000043971(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001107198.1|dip:DIP-61195N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P79 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587103|ensembl:ENSBTAP00000007165 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb11_bovin(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit J(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000005446(gene)|ensembl:ENSBTAT00000007165(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001032560.1|dip:DIP-61196N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q3T0Q3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586729|ensembl:ENSBTAP00000002420|uniprotkb:A7E3Q9 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb3_bovin(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000001856(gene)|ensembl:ENSBTAT00000002420(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001029384.1|dip:DIP-61186N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8MbAcVD98I3FxAXdse0S9jntJpY9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q5E9B8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586926|ensembl:ENSBTAP00000012481 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb7_bovin(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000009483(gene)|ensembl:ENSBTAT00000012481(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001015633.1|dip:DIP-61192N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P73 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587024 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb9_bovin(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001069797.1|dip:DIP-61194N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:szkm9fH0PrnOCaN68cAmBnycGWU9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:P63272 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-727250|uniprotkb:Q16550|uniprotkb:Q62387|uniprotkb:Q6ZP89|uniprotkb:B2R4X8|uniprotkb:D3DTZ4|ensembl:ENSP00000225504|ensembl:ENSP00000462670 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt4h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor small subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 14 kDa subunit(gene name synonym)|uniprotkb:SUPT4H1(gene name)|psi-mi:SUPT4H1(display_short)|uniprotkb:SPT4H(gene name synonym)|uniprotkb:SUPT4H(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_003159.1|ensembl:ENSG00000213246(gene)|ensembl:ENST00000225504(transcript)|ensembl:ENST00000580947(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|mint:P63272|rcsb pdb:3H7H|rcsb pdb:5OIK|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|dip:DIP-40644N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:dz+Mu8lTSRS/nIQ+RUKWIiJAwTE9606 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:O00267 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192983|imex:IM-25349-3|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3MZY8 uniprotkb:A5PJW8 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193012|imex:IM-25349-4|dip:DIP-197747E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rigid:KchVjbTjHHLMUGIEZFe6NqHm0OU false crosslinked residues:212-212 crosslinked residues:327-327|crosslinked residues:458-458|crosslinked residues:815-815|crosslinked residues:214-214 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:O00267 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193039|imex:IM-25349-5|dip:DIP-200910E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:OrFW+/scuuCt5ceccSPxjDBMadA false crosslinked residues:327-327|crosslinked residues:332-332|crosslinked residues:334-334 crosslinked residues:231-231 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:O00267 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193064|imex:IM-25349-6|dip:DIP-200910E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:OrFW+/scuuCt5ceccSPxjDBMadA false crosslinked residues:327-327 crosslinked residues:236-236 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:O00267 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193106|imex:IM-25349-8|dip:DIP-200910E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:OrFW+/scuuCt5ceccSPxjDBMadA false crosslinked residues:264-264 crosslinked residues:236-236 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3MZY8 uniprotkb:A5PJW8 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193085|imex:IM-25349-7|dip:DIP-197747E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rigid:KchVjbTjHHLMUGIEZFe6NqHm0OU false crosslinked residues:213-213 crosslinked residues:327-327 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3MZY8 uniprotkb:A5PJW8 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193127|imex:IM-25349-9|dip:DIP-197747E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rigid:KchVjbTjHHLMUGIEZFe6NqHm0OU false crosslinked residues:1125-1125|crosslinked residues:1135-1135 crosslinked residues:494-494 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:F2Z4H3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586976|ensembl:ENSBTAP00000000606 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:f2z4h3_bovin(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000040199(gene)|ensembl:ENSBTAT00000000606(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001178994.1|dip:DIP-61193N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:G3MZY8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q1JQ91 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586829|ensembl:ENSBTAP00000072181 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:q1jq91_bovin(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000053244(gene)|ensembl:ENSBTAT00000074897(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001069926.1|dip:DIP-61189N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:2OiGCsqaQg5B+ERFRGHuJ0lDWhk9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q2T9T3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586877 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab1_bovin(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001033182.1|dip:DIP-61190N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:Mx5kGREtLV+ucw052BfPrTF6RlM9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q32PE0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586902 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab2_bovin(display_long)|uniprotkb:POLR2F(gene name)|psi-mi:POLR2F(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit F(gene name synonym)|uniprotkb:RPB6 homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:5FLM|rcsb pdb:5OIK|dip:DIP-61191N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fkAqQM+e1h4/cY6430P7sKAPJ1c9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q3ZBC0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587125|ensembl:ENSBTAP00000030490 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab4_bovin(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000022539(gene)|ensembl:ENSBTAT00000030510(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|dip:DIP-61197N|refseq:NP_001032712.1|refseq:NP_001290464.1|refseq:NP_001290465.1|refseq:XP_015321795.1|refseq:XP_015329927.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q32P78 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587047|ensembl:ENSBTAP00000041501 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab5_bovin(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000031061(gene)|ensembl:ENSBTAT00000043971(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001107198.1|dip:DIP-61195N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q32P79 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587103|ensembl:ENSBTAP00000007165 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb11_bovin(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit J(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000005446(gene)|ensembl:ENSBTAT00000007165(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001032560.1|dip:DIP-61196N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q3T0Q3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586729|ensembl:ENSBTAP00000002420|uniprotkb:A7E3Q9 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb3_bovin(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000001856(gene)|ensembl:ENSBTAT00000002420(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001029384.1|dip:DIP-61186N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8MbAcVD98I3FxAXdse0S9jntJpY9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q5E9B8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586926|ensembl:ENSBTAP00000012481 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb7_bovin(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000009483(gene)|ensembl:ENSBTAT00000012481(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001015633.1|dip:DIP-61192N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q32P73 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587024 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb9_bovin(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193229|imex:IM-25349-13|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001069797.1|dip:DIP-61194N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:szkm9fH0PrnOCaN68cAmBnycGWU9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G3MZY8 uniprotkb:O00267 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193208|imex:IM-25349-12|dip:DIP-200911E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:Cn5o9+f+qyfWgUwJHYvx0VKBZdU false crosslinked residues:1866-1866 crosslinked residues:1037-1037 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:F2Z4H3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586976|ensembl:ENSBTAP00000000606 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:f2z4h3_bovin(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000040199(gene)|ensembl:ENSBTAT00000000606(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001178994.1|dip:DIP-61193N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:G3MZY8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:P0CAP2-1 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-16193171|ensembl:ENSP00000299638 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:p0cap2-1(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym)|uniprotkb:Gdown1(isoform synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N intact:EBI-9657655(isoform-parent)|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q1JQ91 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586829|ensembl:ENSBTAP00000072181 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:q1jq91_bovin(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000053244(gene)|ensembl:ENSBTAT00000074897(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001069926.1|dip:DIP-61189N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:2OiGCsqaQg5B+ERFRGHuJ0lDWhk9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q2T9T3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586877 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab1_bovin(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001033182.1|dip:DIP-61190N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:Mx5kGREtLV+ucw052BfPrTF6RlM9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q32PE0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586902 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab2_bovin(display_long)|uniprotkb:POLR2F(gene name)|psi-mi:POLR2F(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit F(gene name synonym)|uniprotkb:RPB6 homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:5FLM|rcsb pdb:5OIK|dip:DIP-61191N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fkAqQM+e1h4/cY6430P7sKAPJ1c9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q3ZBC0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587125|ensembl:ENSBTAP00000030490 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab4_bovin(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000022539(gene)|ensembl:ENSBTAT00000030510(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|dip:DIP-61197N|refseq:NP_001032712.1|refseq:NP_001290464.1|refseq:NP_001290465.1|refseq:XP_015321795.1|refseq:XP_015329927.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q32P78 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587047|ensembl:ENSBTAP00000041501 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab5_bovin(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000031061(gene)|ensembl:ENSBTAT00000043971(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001107198.1|dip:DIP-61195N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q32P79 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587103|ensembl:ENSBTAP00000007165 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb11_bovin(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit J(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000005446(gene)|ensembl:ENSBTAT00000007165(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001032560.1|dip:DIP-61196N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q3T0Q3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586729|ensembl:ENSBTAP00000002420|uniprotkb:A7E3Q9 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb3_bovin(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000001856(gene)|ensembl:ENSBTAT00000002420(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001029384.1|dip:DIP-61186N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8MbAcVD98I3FxAXdse0S9jntJpY9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q5E9B8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586926|ensembl:ENSBTAP00000012481 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb7_bovin(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000009483(gene)|ensembl:ENSBTAT00000012481(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001015633.1|dip:DIP-61192N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A5PJW8 uniprotkb:Q32P73 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587024 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb9_bovin(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193180|imex:IM-25349-11|dip:DIP-200909E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001069797.1|dip:DIP-61194N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:szkm9fH0PrnOCaN68cAmBnycGWU9913 rigid:EW7DglMsU0xy/bNDDtnngI7UUTs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q2T9T3 uniprotkb:G3MZY8 intact:EBI-15586877 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 psi-mi:rpab1_bovin(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193150|imex:IM-25349-10|dip:DIP-197749E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001033182.1|dip:DIP-61190N ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Mx5kGREtLV+ucw052BfPrTF6RlM9913 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rigid:1kPtvXOUBM0dZ1Q7Q1bD1js6CEE false crosslinked residues:88-88 crosslinked residues:179-179 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:O00267 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193279|imex:IM-25349-15|dip:DIP-200910E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:OrFW+/scuuCt5ceccSPxjDBMadA false crosslinked residues:815-815 crosslinked residues:333-333 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3MZY8 uniprotkb:O00267 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193256|imex:IM-25349-14|dip:DIP-200911E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:Cn5o9+f+qyfWgUwJHYvx0VKBZdU false crosslinked residues:212-212 crosslinked residues:231-231|crosslinked residues:258-258 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3MZY8 uniprotkb:A5PJW8 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193300|imex:IM-25349-16|dip:DIP-197747E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rigid:KchVjbTjHHLMUGIEZFe6NqHm0OU false crosslinked residues:1219-1219 crosslinked residues:248-248 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63272 uniprotkb:O00267 intact:EBI-727250|uniprotkb:Q16550|uniprotkb:Q62387|uniprotkb:Q6ZP89|uniprotkb:B2R4X8|uniprotkb:D3DTZ4|ensembl:ENSP00000225504|ensembl:ENSP00000462670 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:spt4h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor small subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 14 kDa subunit(gene name synonym)|uniprotkb:SUPT4H1(gene name)|psi-mi:SUPT4H1(display_short)|uniprotkb:SPT4H(gene name synonym)|uniprotkb:SUPT4H(gene name synonym) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193321|imex:IM-25349-17|dip:DIP-68893E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003159.1|ensembl:ENSG00000213246(gene)|ensembl:ENST00000225504(transcript)|ensembl:ENST00000580947(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|mint:P63272|rcsb pdb:3H7H|rcsb pdb:5OIK|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|dip:DIP-40644N refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:dz+Mu8lTSRS/nIQ+RUKWIiJAwTE9606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:OEz/LroCcD96Gxnk1Zu+v9YeHNk false crosslinked residues:?-? crosslinked residues:268-268|crosslinked residues:274-274 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:F2Z4H3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586976|ensembl:ENSBTAP00000000606 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:f2z4h3_bovin(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000040199(gene)|ensembl:ENSBTAT00000000606(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001178994.1|dip:DIP-61193N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:G3MZY8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q1JQ91 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586829|ensembl:ENSBTAP00000072181 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:q1jq91_bovin(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000053244(gene)|ensembl:ENSBTAT00000074897(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001069926.1|dip:DIP-61189N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:2OiGCsqaQg5B+ERFRGHuJ0lDWhk9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q2T9T3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586877 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab1_bovin(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001033182.1|dip:DIP-61190N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:Mx5kGREtLV+ucw052BfPrTF6RlM9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32PE0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586902 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab2_bovin(display_long)|uniprotkb:POLR2F(gene name)|psi-mi:POLR2F(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit F(gene name synonym)|uniprotkb:RPB6 homolog(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:5FLM|rcsb pdb:5OIK|dip:DIP-61191N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fkAqQM+e1h4/cY6430P7sKAPJ1c9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q3ZBC0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587125|ensembl:ENSBTAP00000030490 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab4_bovin(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000022539(gene)|ensembl:ENSBTAT00000030510(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|dip:DIP-61197N|refseq:NP_001032712.1|refseq:NP_001290464.1|refseq:NP_001290465.1|refseq:XP_015321795.1|refseq:XP_015329927.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P78 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587047|ensembl:ENSBTAP00000041501 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab5_bovin(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000031061(gene)|ensembl:ENSBTAT00000043971(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001107198.1|dip:DIP-61195N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P79 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587103|ensembl:ENSBTAP00000007165 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb11_bovin(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit J(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000005446(gene)|ensembl:ENSBTAT00000007165(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001032560.1|dip:DIP-61196N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q3T0Q3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586729|ensembl:ENSBTAP00000002420|uniprotkb:A7E3Q9 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb3_bovin(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000001856(gene)|ensembl:ENSBTAT00000002420(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001029384.1|dip:DIP-61186N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8MbAcVD98I3FxAXdse0S9jntJpY9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q5E9B8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586926|ensembl:ENSBTAP00000012481 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb7_bovin(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000009483(gene)|ensembl:ENSBTAT00000012481(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001015633.1|dip:DIP-61192N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P73 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587024 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb9_bovin(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193376|imex:IM-25349-19|dip:DIP-200908E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001069797.1|dip:DIP-61194N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:szkm9fH0PrnOCaN68cAmBnycGWU9913 rigid:wTWp+v+FXe1sTVO2fw+aVA3U/wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:F2Z4H3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586976|ensembl:ENSBTAP00000000606 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:f2z4h3_bovin(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000040199(gene)|ensembl:ENSBTAT00000000606(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001178994.1|dip:DIP-61193N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:G3MZY8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q1JQ91 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586829|ensembl:ENSBTAP00000072181 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:q1jq91_bovin(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000053244(gene)|ensembl:ENSBTAT00000074897(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001069926.1|dip:DIP-61189N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:2OiGCsqaQg5B+ERFRGHuJ0lDWhk9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q2T9T3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586877 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab1_bovin(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001033182.1|dip:DIP-61190N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:Mx5kGREtLV+ucw052BfPrTF6RlM9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32PE0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586902 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab2_bovin(display_long)|uniprotkb:POLR2F(gene name)|psi-mi:POLR2F(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit F(gene name synonym)|uniprotkb:RPB6 homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:5FLM|rcsb pdb:5OIK|dip:DIP-61191N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:fkAqQM+e1h4/cY6430P7sKAPJ1c9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q3ZBC0 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587125|ensembl:ENSBTAP00000030490 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab4_bovin(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000022539(gene)|ensembl:ENSBTAT00000030510(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|dip:DIP-61197N|refseq:NP_001032712.1|refseq:NP_001290464.1|refseq:NP_001290465.1|refseq:XP_015321795.1|refseq:XP_015329927.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P78 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587047|ensembl:ENSBTAP00000041501 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpab5_bovin(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000031061(gene)|ensembl:ENSBTAT00000043971(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-5250924|reactome:R-BTA-674695|reactome:R-BTA-73762|refseq:NP_001107198.1|dip:DIP-61195N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P79 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587103|ensembl:ENSBTAP00000007165 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb11_bovin(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit J(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000005446(gene)|ensembl:ENSBTAT00000007165(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001032560.1|dip:DIP-61196N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q3T0Q3 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586729|ensembl:ENSBTAP00000002420|uniprotkb:A7E3Q9 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb3_bovin(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000001856(gene)|ensembl:ENSBTAT00000002420(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|refseq:NP_001029384.1|dip:DIP-61186N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8MbAcVD98I3FxAXdse0S9jntJpY9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q5E9B8 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15586926|ensembl:ENSBTAP00000012481 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb7_bovin(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N ensembl:ENSBTAG00000009483(gene)|ensembl:ENSBTAT00000012481(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001015633.1|dip:DIP-61192N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:Q32P73 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-15587024 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:rpb9_bovin(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001069797.1|dip:DIP-61194N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:szkm9fH0PrnOCaN68cAmBnycGWU9913 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:P63272 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-727250|uniprotkb:Q16550|uniprotkb:Q62387|uniprotkb:Q6ZP89|uniprotkb:B2R4X8|uniprotkb:D3DTZ4|ensembl:ENSP00000225504|ensembl:ENSP00000462670 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt4h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor small subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 14 kDa subunit(gene name synonym)|uniprotkb:SUPT4H1(gene name)|psi-mi:SUPT4H1(display_short)|uniprotkb:SPT4H(gene name synonym)|uniprotkb:SUPT4H(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_003159.1|ensembl:ENSG00000213246(gene)|ensembl:ENST00000225504(transcript)|ensembl:ENST00000580947(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|mint:P63272|rcsb pdb:3H7H|rcsb pdb:5OIK|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|dip:DIP-40644N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:dz+Mu8lTSRS/nIQ+RUKWIiJAwTE9606 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5PJW8 uniprotkb:O00267 intact:EBI-15586776|ensembl:ENSBTAP00000025800|uniprotkb:F1MPP6 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:a5pjw8_bovin(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16193346|imex:IM-25349-18|dip:DIP-200907E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000019366(gene)|ensembl:ENSBTAT00000025800(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:5FLM|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|rcsb pdb:5OIK|refseq:NP_001092552.1|dip:DIP-61188N refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Cs/YlphqKhvWEkUDyflOPkWdY7A9913 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:9Ji9yld2J/qxCLKRKhR04+pq36Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2T9T3 uniprotkb:G3MZY8 intact:EBI-15586877 intact:EBI-6551200|ensembl:ENSBTAP00000055142|ensembl:ENSBTAP00000065848 psi-mi:rpab1_bovin(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:g3mzy8_bovin(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short) psi-mi:"MI:0030"(cross-linking study) Bernecky et al. (2016) pubmed:26789250|doi:10.1038/nature16482|imex:IM-25349 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16193403|imex:IM-25349-20|dip:DIP-197749E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5FLM|rcsb pdb:5OIK|refseq:NP_001033182.1|dip:DIP-61190N ensembl:ENSBTAG00000046765(gene)|ensembl:ENSBTAT00000064788(transcript)|ensembl:ENSBTAT00000069267(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:5FLM|rcsb pdb:5OIK|reactome:R-BTA-113418|reactome:R-BTA-674695|dip:DIP-61187N|refseq:NP_001193242.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2019/04/15 rogid:Mx5kGREtLV+ucw052BfPrTF6RlM9913 rogid:fx06nUPG5pMwLl+egf9keUPQJYg9913 rigid:1kPtvXOUBM0dZ1Q7Q1bD1js6CEE false crosslinked residues:186-186 crosslinked residues:132-132 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)