#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03518 uniprotkb:P03170 intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660 intact:EBI-16192837|uniprotkb:Q99BW2|uniprotkb:Q9E0N0|uniprotkb:Q9E0N1 psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym) psi-mi:icp47_hhv11(display_long)|uniprotkb:US12(gene name)|psi-mi:US12(display_short)|uniprotkb:Immediate-early protein IE12(gene name synonym)|uniprotkb:Immediate-early-5(gene name synonym)|uniprotkb:Infected cell protein 47(gene name synonym)|uniprotkb:US12 protein(gene name synonym)|uniprotkb:Vmw12(gene name synonym) psi-mi:"MI:0096"(pull down) Oldham et al. (2016) pubmed:26789246|doi:10.1038/nature16506|imex:IM-25348 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16192857|imex:IM-25348-1|dip:DIP-200906E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0042025"(host cell nucleus)|interpro:IPR008026(Herpesvirus US12)|rcsb pdb:1QLO|refseq:YP_009137148.1|dip:DIP-61932N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606 rogid:nYHpp269VK8IaIOoRCLR+rDhNCI10299 rigid:z2DnX/WgA5tebvqRRU42TwPJYOw false protein a tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03518 uniprotkb:Q03519 intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660 intact:EBI-780781|uniprotkb:Q9UQ83|uniprotkb:O95410|uniprotkb:B0V2J8|uniprotkb:Q53FI6|uniprotkb:Q5HY71|uniprotkb:Q96PT8|ensembl:ENSP00000364032|ensembl:ENSP00000372599|ensembl:ENSP00000372726|ensembl:ENSP00000390013|ensembl:ENSP00000394101 psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym) psi-mi:tap2_human(display_long)|uniprotkb:ATP-binding cassette sub-family B member 3(gene name synonym)|uniprotkb:Peptide transporter TAP2(gene name synonym)|uniprotkb:Peptide supply factor 2(gene name synonym)|uniprotkb:Peptide transporter PSF2(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 2(gene name synonym)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)|uniprotkb:ABCB3(gene name synonym)|uniprotkb:PSF2(gene name synonym)|uniprotkb:RING11(gene name synonym)|uniprotkb:Y1(gene name synonym)|uniprotkb:Really interesting new gene 11 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Oldham et al. (2016) pubmed:26789246|doi:10.1038/nature16506|imex:IM-25348 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16192857|imex:IM-25348-1|dip:DIP-200906E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N refseq:NP_001276972.1|refseq:NP_000535.3|refseq:NP_061313.2|dip:DIP-322N|ensembl:ENSG00000204267(gene)|ensembl:ENSG00000206235(gene)|ensembl:ENSG00000206299(gene)|ensembl:ENSG00000228582(gene)|ensembl:ENSG00000237599(gene)|ensembl:ENST00000374897(transcript)|ensembl:ENST00000383118(transcript)|ensembl:ENST00000383239(transcript)|ensembl:ENST00000419142(transcript)|ensembl:ENST00000443713(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002489"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046980"(tapasin binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03519|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606 rogid:w7pDqjoSODoB8qMag1ycxcapvQ09606 rigid:z2DnX/WgA5tebvqRRU42TwPJYOw false protein a tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03170 uniprotkb:Q03518 intact:EBI-16192837|uniprotkb:Q99BW2|uniprotkb:Q9E0N0|uniprotkb:Q9E0N1 intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660 psi-mi:icp47_hhv11(display_long)|uniprotkb:US12(gene name)|psi-mi:US12(display_short)|uniprotkb:Immediate-early protein IE12(gene name synonym)|uniprotkb:Immediate-early-5(gene name synonym)|uniprotkb:Infected cell protein 47(gene name synonym)|uniprotkb:US12 protein(gene name synonym)|uniprotkb:Vmw12(gene name synonym) psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Oldham et al. (2016) pubmed:26789246|doi:10.1038/nature16506|imex:IM-25348 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192877|imex:IM-25348-2|dip:DIP-200906E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0042025"(host cell nucleus)|interpro:IPR008026(Herpesvirus US12)|rcsb pdb:1QLO|refseq:YP_009137148.1|dip:DIP-61932N refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nYHpp269VK8IaIOoRCLR+rDhNCI10299 rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606 rigid:z2DnX/WgA5tebvqRRU42TwPJYOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03170 uniprotkb:Q03519 intact:EBI-16192837|uniprotkb:Q99BW2|uniprotkb:Q9E0N0|uniprotkb:Q9E0N1 intact:EBI-780781|uniprotkb:Q9UQ83|uniprotkb:O95410|uniprotkb:B0V2J8|uniprotkb:Q53FI6|uniprotkb:Q5HY71|uniprotkb:Q96PT8|ensembl:ENSP00000364032|ensembl:ENSP00000372599|ensembl:ENSP00000372726|ensembl:ENSP00000390013|ensembl:ENSP00000394101 psi-mi:icp47_hhv11(display_long)|uniprotkb:US12(gene name)|psi-mi:US12(display_short)|uniprotkb:Immediate-early protein IE12(gene name synonym)|uniprotkb:Immediate-early-5(gene name synonym)|uniprotkb:Infected cell protein 47(gene name synonym)|uniprotkb:US12 protein(gene name synonym)|uniprotkb:Vmw12(gene name synonym) psi-mi:tap2_human(display_long)|uniprotkb:ATP-binding cassette sub-family B member 3(gene name synonym)|uniprotkb:Peptide transporter TAP2(gene name synonym)|uniprotkb:Peptide supply factor 2(gene name synonym)|uniprotkb:Peptide transporter PSF2(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 2(gene name synonym)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)|uniprotkb:ABCB3(gene name synonym)|uniprotkb:PSF2(gene name synonym)|uniprotkb:RING11(gene name synonym)|uniprotkb:Y1(gene name synonym)|uniprotkb:Really interesting new gene 11 protein(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Oldham et al. (2016) pubmed:26789246|doi:10.1038/nature16506|imex:IM-25348 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192877|imex:IM-25348-2|dip:DIP-200906E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0042025"(host cell nucleus)|interpro:IPR008026(Herpesvirus US12)|rcsb pdb:1QLO|refseq:YP_009137148.1|dip:DIP-61932N refseq:NP_001276972.1|refseq:NP_000535.3|refseq:NP_061313.2|dip:DIP-322N|ensembl:ENSG00000204267(gene)|ensembl:ENSG00000206235(gene)|ensembl:ENSG00000206299(gene)|ensembl:ENSG00000228582(gene)|ensembl:ENSG00000237599(gene)|ensembl:ENST00000374897(transcript)|ensembl:ENST00000383118(transcript)|ensembl:ENST00000383239(transcript)|ensembl:ENST00000419142(transcript)|ensembl:ENST00000443713(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002489"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046980"(tapasin binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03519|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nYHpp269VK8IaIOoRCLR+rDhNCI10299 rogid:w7pDqjoSODoB8qMag1ycxcapvQ09606 rigid:z2DnX/WgA5tebvqRRU42TwPJYOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03170 uniprotkb:Q03518 intact:EBI-16192837|uniprotkb:Q99BW2|uniprotkb:Q9E0N0|uniprotkb:Q9E0N1 intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660 psi-mi:icp47_hhv11(display_long)|uniprotkb:US12(gene name)|psi-mi:US12(display_short)|uniprotkb:Immediate-early protein IE12(gene name synonym)|uniprotkb:Immediate-early-5(gene name synonym)|uniprotkb:Infected cell protein 47(gene name synonym)|uniprotkb:US12 protein(gene name synonym)|uniprotkb:Vmw12(gene name synonym) psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Oldham et al. (2016) pubmed:26789246|doi:10.1038/nature16506|imex:IM-25348 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192895|imex:IM-25348-3|dip:DIP-200906E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0042025"(host cell nucleus)|interpro:IPR008026(Herpesvirus US12)|rcsb pdb:1QLO|refseq:YP_009137148.1|dip:DIP-61932N refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nYHpp269VK8IaIOoRCLR+rDhNCI10299 rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606 rigid:z2DnX/WgA5tebvqRRU42TwPJYOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03170 uniprotkb:Q03519 intact:EBI-16192837|uniprotkb:Q99BW2|uniprotkb:Q9E0N0|uniprotkb:Q9E0N1 intact:EBI-780781|uniprotkb:Q9UQ83|uniprotkb:O95410|uniprotkb:B0V2J8|uniprotkb:Q53FI6|uniprotkb:Q5HY71|uniprotkb:Q96PT8|ensembl:ENSP00000364032|ensembl:ENSP00000372599|ensembl:ENSP00000372726|ensembl:ENSP00000390013|ensembl:ENSP00000394101 psi-mi:icp47_hhv11(display_long)|uniprotkb:US12(gene name)|psi-mi:US12(display_short)|uniprotkb:Immediate-early protein IE12(gene name synonym)|uniprotkb:Immediate-early-5(gene name synonym)|uniprotkb:Infected cell protein 47(gene name synonym)|uniprotkb:US12 protein(gene name synonym)|uniprotkb:Vmw12(gene name synonym) psi-mi:tap2_human(display_long)|uniprotkb:ATP-binding cassette sub-family B member 3(gene name synonym)|uniprotkb:Peptide transporter TAP2(gene name synonym)|uniprotkb:Peptide supply factor 2(gene name synonym)|uniprotkb:Peptide transporter PSF2(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 2(gene name synonym)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)|uniprotkb:ABCB3(gene name synonym)|uniprotkb:PSF2(gene name synonym)|uniprotkb:RING11(gene name synonym)|uniprotkb:Y1(gene name synonym)|uniprotkb:Really interesting new gene 11 protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Oldham et al. (2016) pubmed:26789246|doi:10.1038/nature16506|imex:IM-25348 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16192895|imex:IM-25348-3|dip:DIP-200906E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039588"(suppression by virus of host antigen processing and presentation)|go:"GO:0042025"(host cell nucleus)|interpro:IPR008026(Herpesvirus US12)|rcsb pdb:1QLO|refseq:YP_009137148.1|dip:DIP-61932N refseq:NP_001276972.1|refseq:NP_000535.3|refseq:NP_061313.2|dip:DIP-322N|ensembl:ENSG00000204267(gene)|ensembl:ENSG00000206235(gene)|ensembl:ENSG00000206299(gene)|ensembl:ENSG00000228582(gene)|ensembl:ENSG00000237599(gene)|ensembl:ENST00000374897(transcript)|ensembl:ENST00000383118(transcript)|ensembl:ENST00000383239(transcript)|ensembl:ENST00000419142(transcript)|ensembl:ENST00000443713(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002489"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046980"(tapasin binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03519|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:nYHpp269VK8IaIOoRCLR+rDhNCI10299 rogid:w7pDqjoSODoB8qMag1ycxcapvQ09606 rigid:z2DnX/WgA5tebvqRRU42TwPJYOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)