#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62837 uniprotkb:Q96EP0 intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718 intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|ensembl:ENSP00000315112|ensembl:ENSP00000496609|uniprotkb:A0A962 psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym) psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Lechtenberg et al. (2016) pubmed:26789245|doi:10.1038/nature16511|imex:IM-25347 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16192746|imex:IM-25347-1|dip:DIP-200905E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168 ensembl:ENSG00000092098(gene)|ensembl:ENSG00000285152(gene)|ensembl:ENST00000324103(transcript)|ensembl:ENST00000647495(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|refseq:NP_060469.4|refseq:NP_001297261.1|ensembl:ENSP00000315112|ensembl:ENST00000559275|ensembl:ENSP00000453574|ensembl:ENST00000642631|ensembl:ENSP00000494011|ensembl:ENSP00000496609|dip:DIP-44034N|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5X0W|rcsb pdb:6GZY|rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|reactome:R-HSA-5357905|reactome:R-HSA-5357956|rcsb pdb:5LJN psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606 rogid:5QylozByg2G8/5LnkorkdY5fPec9606 rigid:aACbN07mQNCtITMVdCjWvuXiO1Q false mutation:85-85|ubiquitinylated lysine:85-85 sufficient binding region:696-1072 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62837 uniprotkb:Q96EP0 intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718 intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|ensembl:ENSP00000315112|ensembl:ENSP00000496609|uniprotkb:A0A962 psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym) psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lechtenberg et al. (2016) pubmed:26789245|doi:10.1038/nature16511|imex:IM-25347 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16192771|imex:IM-25347-2|dip:DIP-200905E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168 ensembl:ENSG00000092098(gene)|ensembl:ENSG00000285152(gene)|ensembl:ENST00000324103(transcript)|ensembl:ENST00000647495(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|refseq:NP_060469.4|refseq:NP_001297261.1|ensembl:ENSP00000315112|ensembl:ENST00000559275|ensembl:ENSP00000453574|ensembl:ENST00000642631|ensembl:ENSP00000494011|ensembl:ENSP00000496609|dip:DIP-44034N|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5X0W|rcsb pdb:6GZY|rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|reactome:R-HSA-5357905|reactome:R-HSA-5357956|rcsb pdb:5LJN psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606 rogid:5QylozByg2G8/5LnkorkdY5fPec9606 rigid:aACbN07mQNCtITMVdCjWvuXiO1Q false mutation:85-85|ubiquitinylated lysine:85-85 sufficient binding region:696-1072 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62837 uniprotkb:Q96EP0 intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718 intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|ensembl:ENSP00000315112|ensembl:ENSP00000496609|uniprotkb:A0A962 psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym) psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lechtenberg et al. (2016) pubmed:26789245|doi:10.1038/nature16511|imex:IM-25347 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16192795|imex:IM-25347-3|dip:DIP-200905E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168 ensembl:ENSG00000092098(gene)|ensembl:ENSG00000285152(gene)|ensembl:ENST00000324103(transcript)|ensembl:ENST00000647495(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|refseq:NP_060469.4|refseq:NP_001297261.1|ensembl:ENSP00000315112|ensembl:ENST00000559275|ensembl:ENSP00000453574|ensembl:ENST00000642631|ensembl:ENSP00000494011|ensembl:ENSP00000496609|dip:DIP-44034N|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5X0W|rcsb pdb:6GZY|rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|reactome:R-HSA-5357905|reactome:R-HSA-5357956|rcsb pdb:5LJN psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606 rogid:5QylozByg2G8/5LnkorkdY5fPec9606 rigid:aACbN07mQNCtITMVdCjWvuXiO1Q false mutation:85-85|ubiquitinylated lysine:85-85 sufficient binding region:696-1072 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)