#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P24719 uniprotkb:P24719 intact:EBI-10690|ensemblfungi:YOR351C|uniprotkb:D6W346 intact:EBI-10690|ensemblfungi:YOR351C|uniprotkb:D6W346 psi-mi:mek1_yeast(display_long)|uniprotkb:MEK1(gene name)|psi-mi:MEK1(display_short)|uniprotkb:MRE4(gene name synonym)|uniprotkb:YOR351C(locus name)|uniprotkb:O6357(orf name) psi-mi:mek1_yeast(display_long)|uniprotkb:MEK1(gene name)|psi-mi:MEK1(display_short)|uniprotkb:MRE4(gene name synonym)|uniprotkb:YOR351C(locus name)|uniprotkb:O6357(orf name) psi-mi:"MI:0424"(protein kinase assay) Chen et al. (2015) pubmed:26682552|doi:10.1371/journal.pbio.1002329|imex:IM-25136 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16189132|imex:IM-25136-1|dip:DIP-200508E - - psi-mi:"MI:0898"(putative self) psi-mi:"MI:0898"(putative self) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR351C(gene)|ensemblfungi:YOR351C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5YYX|rcsb pdb:5YYZ|sgd:S000005878|refseq:NP_014996.3|dip:DIP-675N ensemblfungi:YOR351C(gene)|ensemblfungi:YOR351C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5YYX|rcsb pdb:5YYZ|sgd:S000005878|refseq:NP_014996.3|dip:DIP-675N psi-mi:"MI:0465"(dip) crc64:7E197338881EF6D0 crc64:7E197338881EF6D0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O/sKOpKQpRtJtgVOyUqz7Pa76Y0559292 rogid:O/sKOpKQpRtJtgVOyUqz7Pa76Y0559292 rigid:4srSEYKUQeC2qshILsR5vaYqQi8 false phosphorylated residue:?-? phosphorylated residue:?-? - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32863 uniprotkb:P24719 intact:EBI-14728|uniprotkb:D6VTY8|ensemblfungi:YGL163C intact:EBI-10690|ensemblfungi:YOR351C|uniprotkb:D6W346 psi-mi:rad54_yeast(display_long)|uniprotkb:G1821(orf name)|uniprotkb:YGL163C(locus name)|uniprotkb:RAD54(gene name)|psi-mi:RAD54(display_short) psi-mi:mek1_yeast(display_long)|uniprotkb:MEK1(gene name)|psi-mi:MEK1(display_short)|uniprotkb:MRE4(gene name synonym)|uniprotkb:YOR351C(locus name)|uniprotkb:O6357(orf name) psi-mi:"MI:0424"(protein kinase assay) Chen et al. (2015) pubmed:26682552|doi:10.1371/journal.pbio.1002329|imex:IM-25136 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16189150|imex:IM-25136-2|dip:DIP-200509E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011352.1|sgd:S000003131|ensemblfungi:YGL163C(gene)|ensemblfungi:YGL163C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0046872"(metal ion binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR013967(Rad54, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|dip:DIP-509N ensemblfungi:YOR351C(gene)|ensemblfungi:YOR351C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5YYX|rcsb pdb:5YYZ|sgd:S000005878|refseq:NP_014996.3|dip:DIP-675N psi-mi:"MI:0465"(dip) crc64:2EC0A9B7E3D66292 crc64:7E197338881EF6D0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:CSMd0tHn4RZu+tL/Zp/VBdJqVBA559292 rogid:O/sKOpKQpRtJtgVOyUqz7Pa76Y0559292 rigid:FQQYnpmveTXMq0BCOp7E15pq7v0 false phosphorylated residue:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)