#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P42345	uniprotkb:Q9BVC4-1	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	intact:EBI-16056342|ensembl:ENSP00000457870|ensembl:ENSP00000456405|ensembl:ENSP00000380313|ensembl:ENSP00000455046	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:q9bvc4-1(display_long)|uniprotkb:MLST8(gene name)|psi-mi:MLST8(display_short)|uniprotkb:GBL(gene name synonym)|uniprotkb:LST8(gene name synonym)|uniprotkb:G protein beta subunit-like(gene name synonym)|uniprotkb:Mammalian lethal with SEC13 protein 8(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188577|imex:IM-25462-1|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	intact:EBI-1387471(isoform-parent)|ensembl:ENST00000397124(transcript)|ensembl:ENST00000564088(transcript)|ensembl:ENST00000565250(transcript)|ensembl:ENST00000569417(transcript)|ensembl:ENSG00000167965(gene)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:BQek96xYe/1IaE8vgX3Uvl9vkCc9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42345	uniprotkb:Q8N122	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	intact:EBI-1567928|uniprotkb:Q8N4V9|uniprotkb:Q8TB32|uniprotkb:Q9P2P3|uniprotkb:B2RN36|uniprotkb:C6KEF2|uniprotkb:F5H7J5|ensembl:ENSP00000307272	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:rptor_human(display_long)|uniprotkb:"p150 target of rapamycin (TOR)-scaffold protein"(gene name synonym)|uniprotkb:RPTOR(gene name)|psi-mi:RPTOR(display_short)|uniprotkb:KIAA1303(gene name synonym)|uniprotkb:RAPTOR(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188577|imex:IM-25462-1|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	refseq:NP_001156506.1|refseq:NP_065812.1|dip:DIP-39482N|ensembl:ENSG00000141564(gene)|ensembl:ENST00000306801(transcript)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|mint:Q8N122|rcsb pdb:5H64|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:BOvNcQXqn9hLPxAZeCZhKWbwgOk9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42345	uniprotkb:Q9BVC4-1	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	intact:EBI-16056342|ensembl:ENSP00000457870|ensembl:ENSP00000456405|ensembl:ENSP00000380313|ensembl:ENSP00000455046	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:q9bvc4-1(display_long)|uniprotkb:MLST8(gene name)|psi-mi:MLST8(display_short)|uniprotkb:GBL(gene name synonym)|uniprotkb:LST8(gene name synonym)|uniprotkb:G protein beta subunit-like(gene name synonym)|uniprotkb:Mammalian lethal with SEC13 protein 8(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188595|imex:IM-25462-2|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	intact:EBI-1387471(isoform-parent)|ensembl:ENST00000397124(transcript)|ensembl:ENST00000564088(transcript)|ensembl:ENST00000565250(transcript)|ensembl:ENST00000569417(transcript)|ensembl:ENSG00000167965(gene)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:BQek96xYe/1IaE8vgX3Uvl9vkCc9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42345	uniprotkb:Q8N122	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	intact:EBI-1567928|uniprotkb:Q8N4V9|uniprotkb:Q8TB32|uniprotkb:Q9P2P3|uniprotkb:B2RN36|uniprotkb:C6KEF2|uniprotkb:F5H7J5|ensembl:ENSP00000307272	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:rptor_human(display_long)|uniprotkb:"p150 target of rapamycin (TOR)-scaffold protein"(gene name synonym)|uniprotkb:RPTOR(gene name)|psi-mi:RPTOR(display_short)|uniprotkb:KIAA1303(gene name synonym)|uniprotkb:RAPTOR(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188595|imex:IM-25462-2|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	refseq:NP_001156506.1|refseq:NP_065812.1|dip:DIP-39482N|ensembl:ENSG00000141564(gene)|ensembl:ENST00000306801(transcript)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|mint:Q8N122|rcsb pdb:5H64|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:BOvNcQXqn9hLPxAZeCZhKWbwgOk9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42345	uniprotkb:Q9BVC4-1	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	intact:EBI-16056342|ensembl:ENSP00000457870|ensembl:ENSP00000456405|ensembl:ENSP00000380313|ensembl:ENSP00000455046	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:q9bvc4-1(display_long)|uniprotkb:MLST8(gene name)|psi-mi:MLST8(display_short)|uniprotkb:GBL(gene name synonym)|uniprotkb:LST8(gene name synonym)|uniprotkb:G protein beta subunit-like(gene name synonym)|uniprotkb:Mammalian lethal with SEC13 protein 8(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188613|imex:IM-25462-3|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	intact:EBI-1387471(isoform-parent)|ensembl:ENST00000397124(transcript)|ensembl:ENST00000564088(transcript)|ensembl:ENST00000565250(transcript)|ensembl:ENST00000569417(transcript)|ensembl:ENSG00000167965(gene)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:BQek96xYe/1IaE8vgX3Uvl9vkCc9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42345	uniprotkb:Q8N122	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	intact:EBI-1567928|uniprotkb:Q8N4V9|uniprotkb:Q8TB32|uniprotkb:Q9P2P3|uniprotkb:B2RN36|uniprotkb:C6KEF2|uniprotkb:F5H7J5|ensembl:ENSP00000307272	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:rptor_human(display_long)|uniprotkb:"p150 target of rapamycin (TOR)-scaffold protein"(gene name synonym)|uniprotkb:RPTOR(gene name)|psi-mi:RPTOR(display_short)|uniprotkb:KIAA1303(gene name synonym)|uniprotkb:RAPTOR(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188613|imex:IM-25462-3|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	refseq:NP_001156506.1|refseq:NP_065812.1|dip:DIP-39482N|ensembl:ENSG00000141564(gene)|ensembl:ENST00000306801(transcript)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|mint:Q8N122|rcsb pdb:5H64|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:BOvNcQXqn9hLPxAZeCZhKWbwgOk9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N122	uniprotkb:Q9BVC4-1	intact:EBI-1567928|uniprotkb:Q8N4V9|uniprotkb:Q8TB32|uniprotkb:Q9P2P3|uniprotkb:B2RN36|uniprotkb:C6KEF2|uniprotkb:F5H7J5|ensembl:ENSP00000307272	intact:EBI-16056342|ensembl:ENSP00000457870|ensembl:ENSP00000456405|ensembl:ENSP00000380313|ensembl:ENSP00000455046	psi-mi:rptor_human(display_long)|uniprotkb:"p150 target of rapamycin (TOR)-scaffold protein"(gene name synonym)|uniprotkb:RPTOR(gene name)|psi-mi:RPTOR(display_short)|uniprotkb:KIAA1303(gene name synonym)|uniprotkb:RAPTOR(gene name synonym)	psi-mi:q9bvc4-1(display_long)|uniprotkb:MLST8(gene name)|psi-mi:MLST8(display_short)|uniprotkb:GBL(gene name synonym)|uniprotkb:LST8(gene name synonym)|uniprotkb:G protein beta subunit-like(gene name synonym)|uniprotkb:Mammalian lethal with SEC13 protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188631|imex:IM-25462-4|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001156506.1|refseq:NP_065812.1|dip:DIP-39482N|ensembl:ENSG00000141564(gene)|ensembl:ENST00000306801(transcript)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|mint:Q8N122|rcsb pdb:5H64|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288	intact:EBI-1387471(isoform-parent)|ensembl:ENST00000397124(transcript)|ensembl:ENST00000564088(transcript)|ensembl:ENST00000565250(transcript)|ensembl:ENST00000569417(transcript)|ensembl:ENSG00000167965(gene)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:BOvNcQXqn9hLPxAZeCZhKWbwgOk9606	rogid:BQek96xYe/1IaE8vgX3Uvl9vkCc9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N122	uniprotkb:P42345	intact:EBI-1567928|uniprotkb:Q8N4V9|uniprotkb:Q8TB32|uniprotkb:Q9P2P3|uniprotkb:B2RN36|uniprotkb:C6KEF2|uniprotkb:F5H7J5|ensembl:ENSP00000307272	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	psi-mi:rptor_human(display_long)|uniprotkb:"p150 target of rapamycin (TOR)-scaffold protein"(gene name synonym)|uniprotkb:RPTOR(gene name)|psi-mi:RPTOR(display_short)|uniprotkb:KIAA1303(gene name synonym)|uniprotkb:RAPTOR(gene name synonym)	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188631|imex:IM-25462-4|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001156506.1|refseq:NP_065812.1|dip:DIP-39482N|ensembl:ENSG00000141564(gene)|ensembl:ENST00000306801(transcript)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|mint:Q8N122|rcsb pdb:5H64|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:BOvNcQXqn9hLPxAZeCZhKWbwgOk9606	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42345	uniprotkb:Q9BVC4-1	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	intact:EBI-16056342|ensembl:ENSP00000457870|ensembl:ENSP00000456405|ensembl:ENSP00000380313|ensembl:ENSP00000455046	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:q9bvc4-1(display_long)|uniprotkb:MLST8(gene name)|psi-mi:MLST8(display_short)|uniprotkb:GBL(gene name synonym)|uniprotkb:LST8(gene name synonym)|uniprotkb:G protein beta subunit-like(gene name synonym)|uniprotkb:Mammalian lethal with SEC13 protein 8(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188651|imex:IM-25462-5|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	intact:EBI-1387471(isoform-parent)|ensembl:ENST00000397124(transcript)|ensembl:ENST00000564088(transcript)|ensembl:ENST00000565250(transcript)|ensembl:ENST00000569417(transcript)|ensembl:ENSG00000167965(gene)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:BQek96xYe/1IaE8vgX3Uvl9vkCc9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42345	uniprotkb:Q8N122	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	intact:EBI-1567928|uniprotkb:Q8N4V9|uniprotkb:Q8TB32|uniprotkb:Q9P2P3|uniprotkb:B2RN36|uniprotkb:C6KEF2|uniprotkb:F5H7J5|ensembl:ENSP00000307272	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:rptor_human(display_long)|uniprotkb:"p150 target of rapamycin (TOR)-scaffold protein"(gene name synonym)|uniprotkb:RPTOR(gene name)|psi-mi:RPTOR(display_short)|uniprotkb:KIAA1303(gene name synonym)|uniprotkb:RAPTOR(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Aylett et al. (2016)	pubmed:26678875|doi:10.1126/science.aaa3870|imex:IM-25462	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188651|imex:IM-25462-5|dip:DIP-201198E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	refseq:NP_001156506.1|refseq:NP_065812.1|dip:DIP-39482N|ensembl:ENSG00000141564(gene)|ensembl:ENST00000306801(transcript)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|mint:Q8N122|rcsb pdb:5H64|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:BOvNcQXqn9hLPxAZeCZhKWbwgOk9606	rigid:eSguvBGMCT25C4HVCUAPMQxg1VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)