#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10855	uniprotkb:E9M5R0	intact:EBI-16188162|ensembl:ENSMUSP00000001008|uniprotkb:P14096	intact:EBI-16188152	psi-mi:ccl3_mouse(display_long)|uniprotkb:Ccl3(gene name)|psi-mi:Ccl3(display_short)|uniprotkb:Mip1a(gene name synonym)|uniprotkb:Scya3(gene name synonym)|uniprotkb:Heparin-binding chemotaxis protein(gene name synonym)|uniprotkb:L2G25B(gene name synonym)|uniprotkb:Macrophage inflammatory protein 1-alpha(gene name synonym)|uniprotkb:SIS-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine A3(gene name synonym)|uniprotkb:TY-5(gene name synonym)	psi-mi:e9m5r0_9gama(display_long)|uniprotkb:RHVP-L.R17(orf name)|uniprotkb:RHVP.R17(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Lubman et al. (2016)	pubmed:26671708|doi:10.1016/j.str.2015.10.018|imex:IM-25268	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1605972(cricetid gammaherpesvirus 2)|taxid:1605972(Cricetid gammaherpesvirus 2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188247|imex:IM-25268-1|dip:DIP-200863E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000982(gene)|ensembl:ENSMUST00000001008(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001775"(cell activation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016301"(kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042493"|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:2000503"(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:4ZLT|reactome:R-MMU-380108|go:"GO:0023052"(signaling)|refseq:NP_035467.1|dip:DIP-61916N	rcsb pdb:4ZKQ|rcsb pdb:4ZLT|refseq:YP_004207913.1|dip:DIP-61915N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:aw+2rzSc6idOWeFTu/nGXjTScic10090	rogid:YOEwf3df1OAiOLkYx1ybbgTTKMI1605972	rigid:/xvp9QfKldPUaqbHOB/39285ETk	false	sufficient binding region:24-92	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10148	uniprotkb:E9M5R0	intact:EBI-16188285|ensembl:ENSMUSP00000000193|uniprotkb:Q9QYD7	intact:EBI-16188152	psi-mi:ccl2_mouse(display_long)|uniprotkb:Ccl2(gene name)|psi-mi:Ccl2(display_short)|uniprotkb:Je(gene name synonym)|uniprotkb:Mcp1(gene name synonym)|uniprotkb:Scya2(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 1(gene name synonym)|uniprotkb:Monocyte chemotactic protein 1(gene name synonym)|uniprotkb:Platelet-derived growth factor-inducible protein JE(gene name synonym)|uniprotkb:Small-inducible cytokine A2(gene name synonym)	psi-mi:e9m5r0_9gama(display_long)|uniprotkb:RHVP-L.R17(orf name)|uniprotkb:RHVP.R17(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Lubman et al. (2016)	pubmed:26671708|doi:10.1016/j.str.2015.10.018|imex:IM-25268	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1605972(cricetid gammaherpesvirus 2)|taxid:1605972(Cricetid gammaherpesvirus 2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188395|imex:IM-25268-3|dip:DIP-200864E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000035385(gene)|ensembl:ENSMUST00000000193(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001912"(positive regulation of leukocyte mediated cytotoxicity)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0002693"(positive regulation of cellular extravasation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008009"(chemokine activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0009611"(response to wounding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010574"(regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0014823"(response to activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031727"(CCR2 chemokine receptor binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033552"(response to vitamin B3)|go:"GO:0035684"(helper T cell extravasation)|go:"GO:0035690"|go:"GO:0035702"(monocyte homeostasis)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043679"(axon terminus)|go:"GO:0044299"(C-fiber)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046677"(response to antibiotic)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071403"(cellular response to high density lipoprotein particle stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090265"(positive regulation of immune complex clearance by monocytes and macrophages)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905237"(response to cyclosporin A)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|interpro:IPR039809|refseq:NP_035463.1|dip:DIP-61917N	rcsb pdb:4ZKQ|rcsb pdb:4ZLT|refseq:YP_004207913.1|dip:DIP-61915N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:3KMeOtQ8SinawMAjSgGwtKcduaU10090	rogid:YOEwf3df1OAiOLkYx1ybbgTTKMI1605972	rigid:RiS4lKAvBPKoky7IwuCU1TJxzcM	false	sufficient binding region:24-148|mutation increasing interaction strength:70-70|mutation decreasing interaction strength:71-71|mutation increasing interaction strength:71-71,70-70	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10855	uniprotkb:E9M5R0	intact:EBI-16188162|ensembl:ENSMUSP00000001008|uniprotkb:P14096	intact:EBI-16188152	psi-mi:ccl3_mouse(display_long)|uniprotkb:Ccl3(gene name)|psi-mi:Ccl3(display_short)|uniprotkb:Mip1a(gene name synonym)|uniprotkb:Scya3(gene name synonym)|uniprotkb:Heparin-binding chemotaxis protein(gene name synonym)|uniprotkb:L2G25B(gene name synonym)|uniprotkb:Macrophage inflammatory protein 1-alpha(gene name synonym)|uniprotkb:SIS-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine A3(gene name synonym)|uniprotkb:TY-5(gene name synonym)	psi-mi:e9m5r0_9gama(display_long)|uniprotkb:RHVP-L.R17(orf name)|uniprotkb:RHVP.R17(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Lubman et al. (2016)	pubmed:26671708|doi:10.1016/j.str.2015.10.018|imex:IM-25268	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1605972(cricetid gammaherpesvirus 2)|taxid:1605972(Cricetid gammaherpesvirus 2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188424|imex:IM-25268-4|dip:DIP-200863E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000982(gene)|ensembl:ENSMUST00000001008(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001775"(cell activation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016301"(kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042493"|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:2000503"(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:4ZLT|reactome:R-MMU-380108|go:"GO:0023052"(signaling)|refseq:NP_035467.1|dip:DIP-61916N	rcsb pdb:4ZKQ|rcsb pdb:4ZLT|refseq:YP_004207913.1|dip:DIP-61915N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:aw+2rzSc6idOWeFTu/nGXjTScic10090	rogid:YOEwf3df1OAiOLkYx1ybbgTTKMI1605972	rigid:/xvp9QfKldPUaqbHOB/39285ETk	false	sufficient binding region:24-92	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10855	uniprotkb:E9M5R0	intact:EBI-16188162|ensembl:ENSMUSP00000001008|uniprotkb:P14096	intact:EBI-16188152	psi-mi:ccl3_mouse(display_long)|uniprotkb:Ccl3(gene name)|psi-mi:Ccl3(display_short)|uniprotkb:Mip1a(gene name synonym)|uniprotkb:Scya3(gene name synonym)|uniprotkb:Heparin-binding chemotaxis protein(gene name synonym)|uniprotkb:L2G25B(gene name synonym)|uniprotkb:Macrophage inflammatory protein 1-alpha(gene name synonym)|uniprotkb:SIS-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine A3(gene name synonym)|uniprotkb:TY-5(gene name synonym)	psi-mi:e9m5r0_9gama(display_long)|uniprotkb:RHVP-L.R17(orf name)|uniprotkb:RHVP.R17(orf name)	psi-mi:"MI:0067"(light scattering)	Lubman et al. (2016)	pubmed:26671708|doi:10.1016/j.str.2015.10.018|imex:IM-25268	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1605972(cricetid gammaherpesvirus 2)|taxid:1605972(Cricetid gammaherpesvirus 2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188443|imex:IM-25268-5|dip:DIP-200863E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000982(gene)|ensembl:ENSMUST00000001008(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001775"(cell activation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016301"(kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042493"|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:2000503"(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:4ZLT|reactome:R-MMU-380108|go:"GO:0023052"(signaling)|refseq:NP_035467.1|dip:DIP-61916N	rcsb pdb:4ZKQ|rcsb pdb:4ZLT|refseq:YP_004207913.1|dip:DIP-61915N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:aw+2rzSc6idOWeFTu/nGXjTScic10090	rogid:YOEwf3df1OAiOLkYx1ybbgTTKMI1605972	rigid:/xvp9QfKldPUaqbHOB/39285ETk	false	sufficient binding region:24-92	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10855	uniprotkb:E9M5R0	intact:EBI-16188162|ensembl:ENSMUSP00000001008|uniprotkb:P14096	intact:EBI-16188152	psi-mi:ccl3_mouse(display_long)|uniprotkb:Ccl3(gene name)|psi-mi:Ccl3(display_short)|uniprotkb:Mip1a(gene name synonym)|uniprotkb:Scya3(gene name synonym)|uniprotkb:Heparin-binding chemotaxis protein(gene name synonym)|uniprotkb:L2G25B(gene name synonym)|uniprotkb:Macrophage inflammatory protein 1-alpha(gene name synonym)|uniprotkb:SIS-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine A3(gene name synonym)|uniprotkb:TY-5(gene name synonym)	psi-mi:e9m5r0_9gama(display_long)|uniprotkb:RHVP-L.R17(orf name)|uniprotkb:RHVP.R17(orf name)	psi-mi:"MI:0071"(molecular sieving)	Lubman et al. (2016)	pubmed:26671708|doi:10.1016/j.str.2015.10.018|imex:IM-25268	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1605972(cricetid gammaherpesvirus 2)|taxid:1605972(Cricetid gammaherpesvirus 2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188266|imex:IM-25268-2|dip:DIP-200863E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000982(gene)|ensembl:ENSMUST00000001008(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001775"(cell activation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016301"(kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042493"|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:2000503"(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:4ZLT|reactome:R-MMU-380108|go:"GO:0023052"(signaling)|refseq:NP_035467.1|dip:DIP-61916N	rcsb pdb:4ZKQ|rcsb pdb:4ZLT|refseq:YP_004207913.1|dip:DIP-61915N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:aw+2rzSc6idOWeFTu/nGXjTScic10090	rogid:YOEwf3df1OAiOLkYx1ybbgTTKMI1605972	rigid:/xvp9QfKldPUaqbHOB/39285ETk	false	sufficient binding region:24-92	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10148	uniprotkb:E9M5R0	intact:EBI-16188285|ensembl:ENSMUSP00000000193|uniprotkb:Q9QYD7	intact:EBI-16188152	psi-mi:ccl2_mouse(display_long)|uniprotkb:Ccl2(gene name)|psi-mi:Ccl2(display_short)|uniprotkb:Je(gene name synonym)|uniprotkb:Mcp1(gene name synonym)|uniprotkb:Scya2(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 1(gene name synonym)|uniprotkb:Monocyte chemotactic protein 1(gene name synonym)|uniprotkb:Platelet-derived growth factor-inducible protein JE(gene name synonym)|uniprotkb:Small-inducible cytokine A2(gene name synonym)	psi-mi:e9m5r0_9gama(display_long)|uniprotkb:RHVP-L.R17(orf name)|uniprotkb:RHVP.R17(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Lubman et al. (2016)	pubmed:26671708|doi:10.1016/j.str.2015.10.018|imex:IM-25268	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1605972(cricetid gammaherpesvirus 2)|taxid:1605972(Cricetid gammaherpesvirus 2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16188462|imex:IM-25268-6|dip:DIP-200864E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000035385(gene)|ensembl:ENSMUST00000000193(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001912"(positive regulation of leukocyte mediated cytotoxicity)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0002693"(positive regulation of cellular extravasation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008009"(chemokine activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0009611"(response to wounding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010574"(regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0014823"(response to activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031727"(CCR2 chemokine receptor binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033552"(response to vitamin B3)|go:"GO:0035684"(helper T cell extravasation)|go:"GO:0035690"|go:"GO:0035702"(monocyte homeostasis)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043679"(axon terminus)|go:"GO:0044299"(C-fiber)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046677"(response to antibiotic)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071403"(cellular response to high density lipoprotein particle stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090265"(positive regulation of immune complex clearance by monocytes and macrophages)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905237"(response to cyclosporin A)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|interpro:IPR039809|refseq:NP_035463.1|dip:DIP-61917N	rcsb pdb:4ZKQ|rcsb pdb:4ZLT|refseq:YP_004207913.1|dip:DIP-61915N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:3KMeOtQ8SinawMAjSgGwtKcduaU10090	rogid:YOEwf3df1OAiOLkYx1ybbgTTKMI1605972	rigid:RiS4lKAvBPKoky7IwuCU1TJxzcM	false	sufficient binding region:24-148	mutation disrupting interaction strength:293-294,296-297	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)