#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32334	uniprotkb:Q06810	intact:EBI-11328|uniprotkb:D6VUF0|ensemblfungi:YGR014W	intact:EBI-2068557|uniprotkb:D6W479|uniprotkb:Q6B149|ensemblfungi:YPR075C	psi-mi:msb2_yeast(display_long)|uniprotkb:MSB2(gene name)|psi-mi:MSB2(display_short)|uniprotkb:Multicopy suppressor of bud emergence 2(gene name synonym)|uniprotkb:Osmosensor MSB2(gene name synonym)|uniprotkb:YGR014W(locus name)	psi-mi:opy2_yeast(display_long)|uniprotkb:OPY2(gene name)|psi-mi:OPY2(display_short)|uniprotkb:Overproduction-induced pheromone-resistant protein 2(gene name synonym)|uniprotkb:YPR075C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yamamoto et al. (2015)	imex:IM-26210|pubmed:26598606	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16417205|imex:IM-26210-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR014W(gene)|ensemblfungi:YGR014W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR039295|go:"GO:0009986"(cell surface)|refseq:NP_011528.3|sgd:S000003246|mint:P32334|dip:DIP-1455N	refseq:NP_015400.1|sgd:S000006279|interpro:IPR018571|mint:Q06810|ensemblfungi:YPR075C(gene)|ensemblfungi:YPR075C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)	-	-	-	figure legend:Fig. 2A, 2C, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/09/17	2017/09/27	rogid:UsebPCw3sBOg1xeiMmr80m7b4P4559292	rogid:avNmi6o7WtIkxIyUvhoboBXL8sc559292	rigid:D6CoFNdJDir2oTMzQKwxOCw+5uc	false	ha tag:c-c|sufficient binding region:951-1306,1-48|ha tag:48-48|necessary binding region:961-1117	necessary binding region:30-63|green fluorescent protein tag:c-c|sufficient binding region:1-1,28-360	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32334	uniprotkb:Q06810	intact:EBI-11328|uniprotkb:D6VUF0|ensemblfungi:YGR014W	intact:EBI-2068557|uniprotkb:D6W479|uniprotkb:Q6B149|ensemblfungi:YPR075C	psi-mi:msb2_yeast(display_long)|uniprotkb:MSB2(gene name)|psi-mi:MSB2(display_short)|uniprotkb:Multicopy suppressor of bud emergence 2(gene name synonym)|uniprotkb:Osmosensor MSB2(gene name synonym)|uniprotkb:YGR014W(locus name)	psi-mi:opy2_yeast(display_long)|uniprotkb:OPY2(gene name)|psi-mi:OPY2(display_short)|uniprotkb:Overproduction-induced pheromone-resistant protein 2(gene name synonym)|uniprotkb:YPR075C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yamamoto et al. (2015)	imex:IM-26210|pubmed:26598606	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16417227|imex:IM-26210-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR014W(gene)|ensemblfungi:YGR014W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR039295|go:"GO:0009986"(cell surface)|refseq:NP_011528.3|sgd:S000003246|mint:P32334|dip:DIP-1455N	refseq:NP_015400.1|sgd:S000006279|interpro:IPR018571|mint:Q06810|ensemblfungi:YPR075C(gene)|ensemblfungi:YPR075C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)	-	-	-	figure legend:Fig. 5F, 6A|comment:The interaction was not substantially altered by osmostress|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/09/17	2017/09/18	rogid:UsebPCw3sBOg1xeiMmr80m7b4P4559292	rogid:avNmi6o7WtIkxIyUvhoboBXL8sc559292	rigid:D6CoFNdJDir2oTMzQKwxOCw+5uc	false	ha tag:c-c|sufficient binding region:365-1306,1-48|ha tag:48-48	myc tag:c-c|sufficient binding region:1-1,28-360|mutation decreasing interaction strength:30-30,55-55|mutation decreasing interaction strength:58-58,33-33|mutation disrupting interaction strength:30-30,42-42|mutation disrupting interaction strength:33-33,39-39	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32334	uniprotkb:Q06810	intact:EBI-11328|uniprotkb:D6VUF0|ensemblfungi:YGR014W	intact:EBI-2068557|uniprotkb:D6W479|uniprotkb:Q6B149|ensemblfungi:YPR075C	psi-mi:msb2_yeast(display_long)|uniprotkb:MSB2(gene name)|psi-mi:MSB2(display_short)|uniprotkb:Multicopy suppressor of bud emergence 2(gene name synonym)|uniprotkb:Osmosensor MSB2(gene name synonym)|uniprotkb:YGR014W(locus name)	psi-mi:opy2_yeast(display_long)|uniprotkb:OPY2(gene name)|psi-mi:OPY2(display_short)|uniprotkb:Overproduction-induced pheromone-resistant protein 2(gene name synonym)|uniprotkb:YPR075C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yamamoto et al. (2015)	imex:IM-26210|pubmed:26598606	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16417443|imex:IM-26210-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR014W(gene)|ensemblfungi:YGR014W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR039295|go:"GO:0009986"(cell surface)|refseq:NP_011528.3|sgd:S000003246|mint:P32334|dip:DIP-1455N	refseq:NP_015400.1|sgd:S000006279|interpro:IPR018571|mint:Q06810|ensemblfungi:YPR075C(gene)|ensemblfungi:YPR075C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)	-	-	-	figure legend:Fig. 6E, 7A|comment:The interaction was not substantially altered by osmostress|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/09/17	2017/09/18	rogid:UsebPCw3sBOg1xeiMmr80m7b4P4559292	rogid:avNmi6o7WtIkxIyUvhoboBXL8sc559292	rigid:D6CoFNdJDir2oTMzQKwxOCw+5uc	false	mutation:986-986|ha tag:c-c|sufficient binding region:365-1306,1-48|ha tag:48-48	myc tag:c-c|sufficient binding region:1-1,28-360|mutation:48-48	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)