#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96MS0	uniprotkb:Q99435-1	intact:EBI-1220465|intact:EBI-28975526|ensembl:ENSP00000380903	intact:EBI-16185191|ensembl:ENSP00000390680|ensembl:ENSP00000394612	psi-mi:robo3_human(display_long)|uniprotkb:ROBO3(gene name)|psi-mi:ROBO3(display_short)|uniprotkb:Roundabout-like protein 3(gene name synonym)	psi-mi:q99435-1(display_long)|uniprotkb:NELL2(gene name)|psi-mi:NELL2(display_short)|uniprotkb:NRP2(gene name synonym)|uniprotkb:NEL-like protein 2(gene name synonym)|uniprotkb:Nel-related protein 2(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Jaworski et al. (2015)	pubmed:26586761|doi:10.1126/science.aad2615|imex:IM-25190	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16185199|imex:IM-25190-1|dip:DIP-200672E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000380903|refseq:NP_071765.2|dip:DIP-38410N|ensembl:ENSG00000154134(gene)|ensembl:ENST00000397801(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0030424"(axon)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032987|interpro:IPR036116|interpro:IPR036179|rcsb pdb:6POG|rcsb pdb:6POK|rcsb pdb:6POL|reactome:R-HSA-428542|reactome:R-HSA-9010553|reactome:R-HSA-9010642	intact:EBI-946274(isoform-parent)|ensembl:ENSG00000184613(gene)|ensembl:ENST00000429094(transcript)|ensembl:ENST00000452445(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:vJbjxmtNKZFD8FHp6Qwr227wMh89606	rogid:/NYlmX9iC3H17WXd+u97CVwOD7c9606	rigid:DQGddMz7FtAvHctdtQlKCfmTYvE	false	sufficient binding region:1-883|fc-igg tag:c-c	sufficient binding region:1-784|fc-igg tag:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q96MS0	uniprotkb:Q99435-1	intact:EBI-1220465|intact:EBI-28975526|ensembl:ENSP00000380903	intact:EBI-16185191|ensembl:ENSP00000390680|ensembl:ENSP00000394612	psi-mi:robo3_human(display_long)|uniprotkb:ROBO3(gene name)|psi-mi:ROBO3(display_short)|uniprotkb:Roundabout-like protein 3(gene name synonym)	psi-mi:q99435-1(display_long)|uniprotkb:NELL2(gene name)|psi-mi:NELL2(display_short)|uniprotkb:NRP2(gene name synonym)|uniprotkb:NEL-like protein 2(gene name synonym)|uniprotkb:Nel-related protein 2(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Jaworski et al. (2015)	pubmed:26586761|doi:10.1126/science.aad2615|imex:IM-25190	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16185253|imex:IM-25190-3|dip:DIP-200672E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000380903|refseq:NP_071765.2|dip:DIP-38410N|ensembl:ENSG00000154134(gene)|ensembl:ENST00000397801(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0030424"(axon)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032987|interpro:IPR036116|interpro:IPR036179|rcsb pdb:6POG|rcsb pdb:6POK|rcsb pdb:6POL|reactome:R-HSA-428542|reactome:R-HSA-9010553|reactome:R-HSA-9010642	intact:EBI-946274(isoform-parent)|ensembl:ENSG00000184613(gene)|ensembl:ENST00000429094(transcript)|ensembl:ENST00000452445(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:vJbjxmtNKZFD8FHp6Qwr227wMh89606	rogid:/NYlmX9iC3H17WXd+u97CVwOD7c9606	rigid:DQGddMz7FtAvHctdtQlKCfmTYvE	false	sufficient binding region:1-883|fc-igg tag:c-c	sufficient binding region:1-784|fc-igg tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96MS0	uniprotkb:Q99435-1	intact:EBI-1220465|intact:EBI-28975526|ensembl:ENSP00000380903	intact:EBI-16185191|ensembl:ENSP00000390680|ensembl:ENSP00000394612	psi-mi:robo3_human(display_long)|uniprotkb:ROBO3(gene name)|psi-mi:ROBO3(display_short)|uniprotkb:Roundabout-like protein 3(gene name synonym)	psi-mi:q99435-1(display_long)|uniprotkb:NELL2(gene name)|psi-mi:NELL2(display_short)|uniprotkb:NRP2(gene name synonym)|uniprotkb:NEL-like protein 2(gene name synonym)|uniprotkb:Nel-related protein 2(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Jaworski et al. (2015)	pubmed:26586761|doi:10.1126/science.aad2615|imex:IM-25190	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16185226|imex:IM-25190-2|dip:DIP-200672E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000380903|refseq:NP_071765.2|dip:DIP-38410N|ensembl:ENSG00000154134(gene)|ensembl:ENST00000397801(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0030424"(axon)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032987|interpro:IPR036116|interpro:IPR036179|rcsb pdb:6POG|rcsb pdb:6POK|rcsb pdb:6POL|reactome:R-HSA-428542|reactome:R-HSA-9010553|reactome:R-HSA-9010642	intact:EBI-946274(isoform-parent)|ensembl:ENSG00000184613(gene)|ensembl:ENST00000429094(transcript)|ensembl:ENST00000452445(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:vJbjxmtNKZFD8FHp6Qwr227wMh89606	rogid:/NYlmX9iC3H17WXd+u97CVwOD7c9606	rigid:DQGddMz7FtAvHctdtQlKCfmTYvE	false	sufficient binding region:538-883|flag tag:c-c	sufficient binding region:1-784|fc-igg tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6N7	uniprotkb:Q9R1B9	intact:EBI-399762|uniprotkb:Q7Z300|uniprotkb:Q9BUS7|uniprotkb:D3DU36|uniprotkb:B2RXI1|uniprotkb:E9PD49|uniprotkb:Q1RMC7|ensembl:ENSP00000420321	intact:EBI-16185280|ensembl:ENSMUSP00000133840|uniprotkb:E9QKB4|uniprotkb:Q9Z166	psi-mi:robo1_human(display_long)|uniprotkb:ROBO1(gene name)|psi-mi:ROBO1(display_short)|uniprotkb:DUTT1(gene name synonym)|uniprotkb:H-Robo-1(gene name synonym)|uniprotkb:Deleted in U twenty twenty(gene name synonym)	psi-mi:slit2_mouse(display_long)|uniprotkb:Slit2(gene name)|psi-mi:Slit2(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Jaworski et al. (2015)	pubmed:26586761|doi:10.1126/science.aad2615|imex:IM-25190	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16185367|imex:IM-25190-4|dip:DIP-200673E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139317.1|refseq:NP_002932.1|refseq:NP_598334.2|ensembl:ENSP00000420321|ensembl:ENST00000467549|ensembl:ENSP00000417992|ensembl:ENST00000495273|ensembl:ENSP00000420637|refseq:XP_006713340.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032986|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2EO9|rcsb pdb:2V9Q|rcsb pdb:2V9R|rcsb pdb:2V9T|rcsb pdb:3WIH|rcsb pdb:4HLJ|rcsb pdb:5O5G|rcsb pdb:5O5I|rcsb pdb:5OPE|rcsb pdb:6A77|rcsb pdb:6A78|ensembl:ENSG00000169855(gene)|ensembl:ENST00000464233(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009986"(cell surface)|refseq:XP_016862472.1|dip:DIP-33034N|rcsb pdb:6A79|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-8985801|reactome:R-HSA-9010553	ensembl:ENSMUSG00000031558(gene)|ensembl:ENSMUST00000173107(transcript)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002689"(negative regulation of leukocyte chemotaxis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021972"(corticospinal neuron axon guidance through spinal cord)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0050929"(induction of negative chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071676"(negative regulation of mononuclear cell migration)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|go:"GO:0090027"(negative regulation of monocyte chemotaxis)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|mint:Q9R1B9|reactome:R-MMU-376176|reactome:R-MMU-428890|reactome:R-MMU-8985586|reactome:R-MMU-9010553|go:"GO:0022029"(telencephalon cell migration)|refseq:NP_848919.3|dip:DIP-61876N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:LLHEVlylzhWB/zr77pQrNizgVsg9606	rogid:0t9tDMAtdhScxRbDi5grpBl8GT810090	rigid:q2j7k5n5EEF1Nnr5h+EBSzrlfNo	false	sufficient binding region:1-718|fc-igg tag:c-c	his tag:c-c|sufficient binding region:26-900	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)