#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q3UP24	uniprotkb:Q3UP24	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Diebolder et al. (2015)	pubmed:26585513|doi:10.1016/j.str.2015.10.001|imex:IM-25130	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16185028|imex:IM-25130-1|dip:DIP-200468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:OiMuYxH6LPhS9jlwHZo8/0GDTT8	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R016	uniprotkb:P06179	intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029	intact:EBI-2011501|uniprotkb:P97160|uniprotkb:Q02871|uniprotkb:Q56088|ensemblbacteria:AAL20871	psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym)	psi-mi:flic_salty(display_long)|uniprotkb:fliC(gene name)|psi-mi:fliC(display_short)|uniprotkb:flaF(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:Phase 1-I flagellin(gene name synonym)|uniprotkb:STM1959(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Diebolder et al. (2015)	pubmed:26585513|doi:10.1016/j.str.2015.10.001|imex:IM-25130	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16185044|imex:IM-25130-2|dip:DIP-200469E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2	refseq:NP_460912.1|refseq:WP_000079805.1|dip:DIP-43768N|mint:P06179|ensemblbacteria:AAL20871(transcript)|ensemblbacteria:STM1959(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR014981(Flagellin D3)|interpro:IPR042187|rcsb pdb:1IO1|rcsb pdb:1P95|rcsb pdb:1UCU|rcsb pdb:3A5X|rcsb pdb:5YUD|rcsb pdb:6CH3|reactome:R-GGA-433822|reactome:R-GGA-451534|reactome:R-GGA-977240|reactome:R-HSA-844623	psi-mi:"MI:0465"(dip)	-	crc64:4BD7849FA3B936BA	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090	rogid:0JWcURU8Owt3IW+XBPx9sRk/Ou899287	rigid:60AoeF4tBXAw7T4ZOZPpun4hJME	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R016	uniprotkb:Q3UP24	intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Diebolder et al. (2015)	pubmed:26585513|doi:10.1016/j.str.2015.10.001|imex:IM-25130	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16185044|imex:IM-25130-2|dip:DIP-200469E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:60AoeF4tBXAw7T4ZOZPpun4hJME	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)