#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96P20	uniprotkb:Q7Z434-1	intact:EBI-6253230|uniprotkb:B2RC97|uniprotkb:B7ZKS9|uniprotkb:A0A024R5Q0|uniprotkb:B7ZKT2|uniprotkb:B7ZKT3|uniprotkb:O75434|uniprotkb:Q17RS2|uniprotkb:Q59H68|uniprotkb:Q5JQS8|uniprotkb:Q5JQS9|uniprotkb:Q6TG35|uniprotkb:Q8TCW0|uniprotkb:Q8TEU9|uniprotkb:Q8WXH9	intact:EBI-15577799|ensembl:ENSP00000401980	psi-mi:nlrp3_human(display_long)|uniprotkb:NLRP3(gene name)|psi-mi:NLRP3(display_short)|uniprotkb:C1orf7(gene name synonym)|uniprotkb:CIAS1(gene name synonym)|uniprotkb:NALP3(gene name synonym)|uniprotkb:PYPAF1(gene name synonym)|uniprotkb:Angiotensin/vasopressin receptor AII/AVP-like(gene name synonym)|uniprotkb:Caterpiller protein 1.1(gene name synonym)|uniprotkb:Cryopyrin(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 1(gene name synonym)|uniprotkb:Cold-induced autoinflammatory syndrome 1 protein(gene name synonym)	psi-mi:q7z434-1(display_long)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182207|imex:IM-25189-2|dip:DIP-200671E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000139"(Golgi membrane)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR004020(Pyrin)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR027417|interpro:IPR029495|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|rcsb pdb:2NAQ|rcsb pdb:3QF2|rcsb pdb:6NPY|refseq:XP_011542350.1|reactome:R-HSA-9707564|reactome:R-HSA-844456|refseq:NP_001073289.1|refseq:NP_001120933.1|refseq:NP_001120934.1|refseq:NP_001230062.1|refseq:NP_004886.3|refseq:NP_899632.1|reactome:R-HSA-5689901|refseq:XP_016855670.1|refseq:XP_016855671.1|refseq:XP_016855672.1|refseq:XP_016855673.1|dip:DIP-41153N|reactome:R-HSA-9660826	ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|intact:EBI-995373(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:OCkmgUVtTAdyHLRCQlUZ4QFKmX49606	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rigid:hZNHL05QEWskYYMR8sk45OvUXH8	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O35286	uniprotkb:Q91WS2	intact:EBI-8322087|uniprotkb:Q99L91|intact:MINT-4093075|ensembl:ENSMUSP00000031061	intact:EBI-16182145|ensembl:ENSMUSP00000139357|uniprotkb:C9W978|uniprotkb:F8UKQ6|uniprotkb:Q67EY0|uniprotkb:Q8K0L4	psi-mi:dhx15_mouse(display_long)|uniprotkb:Dhx15(gene name)|psi-mi:Dhx15(display_short)|uniprotkb:Ddx15(gene name synonym)|uniprotkb:Deah9(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)	psi-mi:nlrp6_mouse(display_long)|uniprotkb:Nlrp6(gene name)|psi-mi:Nlrp6(display_short)|uniprotkb:Nalp6(gene name synonym)|uniprotkb:Navr(gene name synonym)|uniprotkb:Pypaf5(gene name synonym)|uniprotkb:Angiotensin II/vasopressin receptor(gene name synonym)|uniprotkb:Non-angiotensin-vasopressin receptor(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 5-like(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182190|imex:IM-25189-1|dip:DIP-200667E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031865.2|dip:DIP-61875N|ensembl:ENSMUSG00000029169(gene)|ensembl:ENSMUST00000031061(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O35286|reactome:R-MMU-72163	ensembl:ENSMUSG00000038745(gene)|ensembl:ENSMUST00000183845(transcript)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0005000"(vasopressin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042277"(peptide binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070255"(regulation of mucus secretion)|go:"GO:0070266"(necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070946"(neutrophil-mediated killing of gram-positive bacterium)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|refseq:NP_598707.2|refseq:XP_006536212.1|dip:DIP-61874N	psi-mi:"MI:0465"(dip)	comment:mint|function:Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:3ypGFohz40OvVMkbdam/EUAw9hc10090	rogid:2SgM6Zybr5pdJ/K41hjR3KYQOnk10090	rigid:V1RSZ9hwepMKIAbsnBDNebjwCgE	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:O43143	uniprotkb:Q91WS2-1	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741	intact:EBI-16182226|ensembl:ENSMUSP00000139357	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)	psi-mi:q91ws2-1(display_long)|uniprotkb:Nlrp6(gene name)|psi-mi:Nlrp6(display_short)|uniprotkb:Nalp6(gene name synonym)|uniprotkb:Navr(gene name synonym)|uniprotkb:Pypaf5(gene name synonym)|uniprotkb:NAVR(isoform synonym)|uniprotkb:Angiotensin II/vasopressin receptor(gene name synonym)|uniprotkb:Non-angiotensin-vasopressin receptor(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 5-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182238|imex:IM-25189-3|dip:DIP-200668E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)	ensembl:ENSMUSG00000038745(gene)|ensembl:ENSMUST00000183845(transcript)|intact:EBI-16182145(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	rogid:2SgM6Zybr5pdJ/K41hjR3KYQOnk10090	rigid:SM9iVcRsuidZuRbH7UgLaIH/wz4	false	-	flag tag:?-?	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:O95786-1	uniprotkb:Q7Z434-1	intact:EBI-15577823|ensembl:ENSP00000369213	intact:EBI-15577799|ensembl:ENSP00000401980	psi-mi:o95786-1(display_long)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)	psi-mi:q7z434-1(display_long)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182316|imex:IM-25189-7|dip:DIP-64254E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|intact:EBI-995350(isoform-parent)	ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|intact:EBI-995373(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rigid:obR2EHoHumN9pPBg9pR31HUKako	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7Z434-1	uniprotkb:Q91WS2-1	intact:EBI-15577799|ensembl:ENSP00000401980	intact:EBI-16182226|ensembl:ENSMUSP00000139357	psi-mi:q7z434-1(display_long)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:q91ws2-1(display_long)|uniprotkb:Nlrp6(gene name)|psi-mi:Nlrp6(display_short)|uniprotkb:Nalp6(gene name synonym)|uniprotkb:Navr(gene name synonym)|uniprotkb:Pypaf5(gene name synonym)|uniprotkb:NAVR(isoform synonym)|uniprotkb:Angiotensin II/vasopressin receptor(gene name synonym)|uniprotkb:Non-angiotensin-vasopressin receptor(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 5-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182335|imex:IM-25189-8|dip:DIP-200669E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|intact:EBI-995373(isoform-parent)	ensembl:ENSMUSG00000038745(gene)|ensembl:ENSMUST00000183845(transcript)|intact:EBI-16182145(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rogid:2SgM6Zybr5pdJ/K41hjR3KYQOnk10090	rigid:0Qw/0epzJ3AtKwCxRAyTvIXzpiA	false	flag tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8VCF0	uniprotkb:O35286	intact:EBI-3862816|ensembl:ENSMUSP00000038339|ensembl:ENSMUSP00000105828	intact:EBI-8322087|uniprotkb:Q99L91|intact:MINT-4093075|ensembl:ENSMUSP00000031061	psi-mi:mavs_mouse(display_long)|uniprotkb:Mavs(gene name)|psi-mi:Mavs(display_short)|uniprotkb:Ips1(gene name synonym)|uniprotkb:Visa(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:dhx15_mouse(display_long)|uniprotkb:Dhx15(gene name)|psi-mi:Dhx15(display_short)|uniprotkb:Ddx15(gene name synonym)|uniprotkb:Deah9(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182299|imex:IM-25189-6|dip:DIP-200670E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193314.1|refseq:NP_659137.1|dip:DIP-43890N|ensembl:ENSMUSG00000037523(gene)|ensembl:ENSMUST00000041362(transcript)|ensembl:ENSMUST00000110199(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q8VCF0|rcsb pdb:4GHU|reactome:R-MMU-168928|reactome:R-MMU-936440	refseq:NP_031865.2|dip:DIP-61875N|ensembl:ENSMUSG00000029169(gene)|ensembl:ENSMUST00000031061(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O35286|reactome:R-MMU-72163	psi-mi:"MI:0465"(dip)	-	comment:mint|function:Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:ffvMw8iY9tllLKmqNE+WCP0Bk/E10090	rogid:3ypGFohz40OvVMkbdam/EUAw9hc10090	rigid:/zAkDENoETTtqqNc3/J1dc8GeJ0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43143	uniprotkb:Q91WS2-1	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741	intact:EBI-16182226|ensembl:ENSMUSP00000139357	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)	psi-mi:q91ws2-1(display_long)|uniprotkb:Nlrp6(gene name)|psi-mi:Nlrp6(display_short)|uniprotkb:Nalp6(gene name synonym)|uniprotkb:Navr(gene name synonym)|uniprotkb:Pypaf5(gene name synonym)|uniprotkb:NAVR(isoform synonym)|uniprotkb:Angiotensin II/vasopressin receptor(gene name synonym)|uniprotkb:Non-angiotensin-vasopressin receptor(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 5-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182358|imex:IM-25189-9|dip:DIP-200668E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)	ensembl:ENSMUSG00000038745(gene)|ensembl:ENSMUST00000183845(transcript)|intact:EBI-16182145(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	rogid:2SgM6Zybr5pdJ/K41hjR3KYQOnk10090	rigid:SM9iVcRsuidZuRbH7UgLaIH/wz4	false	-	flag tag:?-?|sufficient binding region:170-715	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35286	uniprotkb:Q91WS2-1	intact:EBI-8322087|uniprotkb:Q99L91|intact:MINT-4093075|ensembl:ENSMUSP00000031061	intact:EBI-16182226|ensembl:ENSMUSP00000139357	psi-mi:dhx15_mouse(display_long)|uniprotkb:Dhx15(gene name)|psi-mi:Dhx15(display_short)|uniprotkb:Ddx15(gene name synonym)|uniprotkb:Deah9(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)	psi-mi:q91ws2-1(display_long)|uniprotkb:Nlrp6(gene name)|psi-mi:Nlrp6(display_short)|uniprotkb:Nalp6(gene name synonym)|uniprotkb:Navr(gene name synonym)|uniprotkb:Pypaf5(gene name synonym)|uniprotkb:NAVR(isoform synonym)|uniprotkb:Angiotensin II/vasopressin receptor(gene name synonym)|uniprotkb:Non-angiotensin-vasopressin receptor(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 5-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182259|imex:IM-25189-4|dip:DIP-200667E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031865.2|dip:DIP-61875N|ensembl:ENSMUSG00000029169(gene)|ensembl:ENSMUST00000031061(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O35286|reactome:R-MMU-72163	ensembl:ENSMUSG00000038745(gene)|ensembl:ENSMUST00000183845(transcript)|intact:EBI-16182145(isoform-parent)	psi-mi:"MI:0465"(dip)	comment:mint|function:Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:3ypGFohz40OvVMkbdam/EUAw9hc10090	rogid:2SgM6Zybr5pdJ/K41hjR3KYQOnk10090	rigid:V1RSZ9hwepMKIAbsnBDNebjwCgE	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O35286	uniprotkb:Q91WS2	intact:EBI-8322087|uniprotkb:Q99L91|intact:MINT-4093075|ensembl:ENSMUSP00000031061	intact:EBI-16182145|ensembl:ENSMUSP00000139357|uniprotkb:C9W978|uniprotkb:F8UKQ6|uniprotkb:Q67EY0|uniprotkb:Q8K0L4	psi-mi:dhx15_mouse(display_long)|uniprotkb:Dhx15(gene name)|psi-mi:Dhx15(display_short)|uniprotkb:Ddx15(gene name synonym)|uniprotkb:Deah9(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)	psi-mi:nlrp6_mouse(display_long)|uniprotkb:Nlrp6(gene name)|psi-mi:Nlrp6(display_short)|uniprotkb:Nalp6(gene name synonym)|uniprotkb:Navr(gene name synonym)|uniprotkb:Pypaf5(gene name synonym)|uniprotkb:Angiotensin II/vasopressin receptor(gene name synonym)|uniprotkb:Non-angiotensin-vasopressin receptor(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 5-like(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182282|imex:IM-25189-5|dip:DIP-200667E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031865.2|dip:DIP-61875N|ensembl:ENSMUSG00000029169(gene)|ensembl:ENSMUST00000031061(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O35286|reactome:R-MMU-72163	ensembl:ENSMUSG00000038745(gene)|ensembl:ENSMUST00000183845(transcript)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0005000"(vasopressin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042277"(peptide binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070255"(regulation of mucus secretion)|go:"GO:0070266"(necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070946"(neutrophil-mediated killing of gram-positive bacterium)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|refseq:NP_598707.2|refseq:XP_006536212.1|dip:DIP-61874N	psi-mi:"MI:0465"(dip)	comment:mint|function:Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:3ypGFohz40OvVMkbdam/EUAw9hc10090	rogid:2SgM6Zybr5pdJ/K41hjR3KYQOnk10090	rigid:V1RSZ9hwepMKIAbsnBDNebjwCgE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z434-1	uniprotkb:Q91WS2-1	intact:EBI-15577799|ensembl:ENSP00000401980	intact:EBI-16182226|ensembl:ENSMUSP00000139357	psi-mi:q7z434-1(display_long)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)	psi-mi:q91ws2-1(display_long)|uniprotkb:Nlrp6(gene name)|psi-mi:Nlrp6(display_short)|uniprotkb:Nalp6(gene name synonym)|uniprotkb:Navr(gene name synonym)|uniprotkb:Pypaf5(gene name synonym)|uniprotkb:NAVR(isoform synonym)|uniprotkb:Angiotensin II/vasopressin receptor(gene name synonym)|uniprotkb:Non-angiotensin-vasopressin receptor(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 5-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2015)	pubmed:26494172|doi:10.1126/science.aab3145|imex:IM-25189	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16182381|imex:IM-25189-10|dip:DIP-200669E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|intact:EBI-995373(isoform-parent)	ensembl:ENSMUSG00000038745(gene)|ensembl:ENSMUST00000183845(transcript)|intact:EBI-16182145(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rogid:2SgM6Zybr5pdJ/K41hjR3KYQOnk10090	rigid:0Qw/0epzJ3AtKwCxRAyTvIXzpiA	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)