#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q16082 uniprotkb:Q8R0Y8 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8357140|intact:MINT-1861655|ensembl:ENSMUSP00000065903|ensembl:ENSMUSP00000105754 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:s2542_mouse(display_long)|uniprotkb:Slc25a42(gene name)|psi-mi:Slc25a42(display_short)|uniprotkb:Solute carrier family 25 member 42(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_001007571.1|ensembl:ENSMUSG00000002346(gene)|ensembl:ENSMUST00000063788(transcript)|ensembl:ENSMUST00000110127(transcript)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0015217"(ADP transmembrane transporter activity)|go:"GO:0015228"(coenzyme A transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0015867"(ATP transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035349"(coenzyme A transmembrane transport)|go:"GO:0043262"(adenosine-diphosphatase activity)|go:"GO:0080121"(AMP transport)|go:"GO:0080122"(AMP transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002167(Graves disease carrier protein)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR018108|interpro:IPR023395|mint:Q8R0Y8 - - comment:mint figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:5FDNzfwou+gFMtOgp/zcuPB3+UU10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P51150 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8321380|intact:MINT-1864693|ensembl:ENSMUSP00000092658|ensembl:ENSMUSP00000109226|ensembl:ENSMUSP00000109227|ensembl:ENSMUSP00000109228|ensembl:ENSMUSP00000109230 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:rab7a_mouse(display_long)|uniprotkb:Rab7a(gene name)|psi-mi:Rab7a(display_short)|uniprotkb:Rab7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_001280581.1|refseq:NP_001280582.1|refseq:NP_001280583.1|refseq:NP_001280584.1|refseq:NP_033031.2|dip:DIP-60513N|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9013148|ensembl:ENSMUSG00000079477(gene)|ensembl:ENSMUST00000095048(transcript)|ensembl:ENSMUST00000113596(transcript)|ensembl:ENSMUST00000113597(transcript)|ensembl:ENSMUST00000113598(transcript)|ensembl:ENSMUST00000113600(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045453"(bone resorption)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0061724"(lipophagy)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51150|rcsb pdb:5Z2M|reactome:R-MMU-2132295|reactome:R-MMU-6798695|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198 - - comment:mint|function:"Involved in late endocytic transport. Contributes to the maturation of phagosomes (acidification)" figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:O88492 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8347295|uniprotkb:Q69Z80|uniprotkb:E9QN72|intact:MINT-4105562|uniprotkb:Q8BNV5|ensembl:ENSMUSP00000002908|ensembl:ENSMUSP00000139859 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:plin4_mouse(display_long)|uniprotkb:Kiaa1881(gene name synonym)|uniprotkb:Adipocyte protein S3-12(gene name synonym)|uniprotkb:Plin4(gene name)|psi-mi:Plin4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_065593.2|ensembl:ENSMUSG00000002831(gene)|ensembl:ENSMUST00000002908(transcript)|ensembl:ENSMUST00000190703(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR004279(Perilipin)|mint:O88492 - - comment:mint|function:May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:VIrsWg+3qqLWYOcp+l6NNgXcG2M10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q8BW75 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8334324|uniprotkb:Q8C0B2|intact:MINT-1861050|uniprotkb:Q14CG9|ensembl:ENSMUSP00000040550 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:aofb_mouse(display_long)|uniprotkb:Maob(gene name)|psi-mi:Maob(display_short)|uniprotkb:Monoamine oxidase type B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_766366.2|ensembl:ENSMUSG00000040147(gene)|ensembl:ENSMUST00000040820(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0014063"(negative regulation of serotonin secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0097621"(monoamine oxidase activity)|interpro:IPR001613(Flavin-containing amine oxidase)|interpro:IPR002937(Amine oxidase)|interpro:IPR036188|mint:Q8BW75|reactome:R-MMU-141333 - - comment:mint|function:Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:CbRCSEelxJ/b3pRGR6ksxbqG4hM10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P02468 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-7059830|intact:MINT-1031545 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:lamc1_mouse(display_long)|uniprotkb:Lamc1(gene name)|psi-mi:Lamc1(display_short)|uniprotkb:Lamb-2(gene name synonym)|uniprotkb:Lamc-1(gene name synonym)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 mint:P02468|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|rcsb pdb:1KLO|rcsb pdb:1NPE|rcsb pdb:1TLE|rcsb pdb:4AQT|rcsb pdb:5MC9|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8874081|dip:DIP-41793N - - comment:mint|function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:LTc4oIJUjQ8INjkodiPpXvL/rx010090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q99PR8 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8346467|intact:MINT-4098113|uniprotkb:E9QKE3|uniprotkb:Q9CZC2|ensembl:ENSMUSP00000042374 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:hspb2_mouse(display_long)|uniprotkb:Hspb2(gene name)|psi-mi:Hspb2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_001158180.1|refseq:NP_077761.3|ensembl:ENSMUSG00000038086(gene)|ensembl:ENSMUST00000042790(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009408"(response to heat)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|mint:Q99PR8 - - comment:mint figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:ERCm6iC+wGPVhmqEZvOPYKgfbxE10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P22315 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-7174007|intact:MINT-1842883 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:hemh_mouse(display_long)|uniprotkb:Fech(gene name)|psi-mi:Fech(display_short)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 mint:P22315|interpro:IPR033644|interpro:IPR033659|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009589"(detection of UV)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010999"(regulation of eIF2 alpha phosphorylation by heme)|go:"GO:0020037"(heme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046906"(tetrapyrrole binding)|go:"GO:0046984"(regulation of hemoglobin biosynthetic process)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0055072"(iron ion homeostasis)|reactome:R-MMU-189451|go:"GO:0004325"(ferrochelatase activity)|interpro:IPR019772|interpro:IPR001015(Ferrochelatase) - - function:Catalyzes the ferrous insertion into protoporphyrin IX|comment:mint|function:"Defects in Fech are the cause of a viable autosomal recessive mutation (named Fechm1Pas or Fch) that causes jaundice and anemia" figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:XE7oTrCC8NCTJTGX6SBaphYeSFs10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9D172 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8321099|intact:MINT-1841972|ensembl:ENSMUSP00000001242 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:gal3a_mouse(display_long)|uniprotkb:Gatd3(gene name)|psi-mi:Gatd3(display_short)|uniprotkb:D10Jhu81e(gene name synonym)|uniprotkb:Gatd3a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_613067.1|ensembl:ENSMUSG00000053329(gene)|ensembl:ENSMUST00000001242(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR029062|mint:Q9D172 - - comment:mint figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:yaWG8Dudv7cOIDqG+5bFSWgJ5+810090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P47934 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8346602|uniprotkb:Q923A6|uniprotkb:Q3TCG3|intact:MINT-4089666|uniprotkb:Q3V1Y3|ensembl:ENSMUSP00000028207|ensembl:ENSMUSP00000099919 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:cacp_mouse(display_long)|uniprotkb:Crat(gene name)|psi-mi:Crat(display_short)|uniprotkb:Carnitine acetyltransferase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_031786.2|ensembl:ENSMUSG00000026853(gene)|ensembl:ENSMUST00000028207(transcript)|ensembl:ENSMUST00000102855(transcript)|go:"GO:0003997"(acyl-CoA oxidase activity)|go:"GO:0004092"(carnitine O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008458"(carnitine O-octanoyltransferase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0046459"(short-chain fatty acid metabolic process)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042231|mint:P47934|rcsb pdb:1NDB|rcsb pdb:1NDF|rcsb pdb:1NDI|rcsb pdb:1T7N|rcsb pdb:1T7O|rcsb pdb:1T7Q|rcsb pdb:2H3P|rcsb pdb:2H3U|rcsb pdb:2H3W|reactome:R-MMU-389887|reactome:R-MMU-9033241 - - function:Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria|comment:mint figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:0M/qKmIjnQiSzBdagoRdKY3SE8A10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P52825 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8346634|uniprotkb:Q3TFS0|intact:MINT-1845154|ensembl:ENSMUSP00000030345 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:cpt2_mouse(display_long)|uniprotkb:Cpt2(gene name)|psi-mi:Cpt2(display_short)|uniprotkb:Cpt-2(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_034079.2|ensembl:ENSMUSG00000028607(gene)|ensembl:ENSMUST00000030345(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008458"(carnitine O-octanoyltransferase activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042572|mint:P52825|reactome:R-MMU-200425 - - comment:mint figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:HX7YZJp2YAQa/ffpoO0hdnHbn6o10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q924X2 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8344171|uniprotkb:O35287|intact:MINT-4091986|uniprotkb:Q9QYP4|ensembl:ENSMUSP00000104936 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:cpt1b_mouse(display_long)|uniprotkb:Cpt1b(gene name)|psi-mi:Cpt1b(display_short)|uniprotkb:Carnitine O-palmitoyltransferase I, muscle isoform(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase 1B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_034078.2|ensembl:ENSMUSG00000078937(gene)|ensembl:ENSMUST00000109313(transcript)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009637"(response to blue light)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR032476|interpro:IPR039551|interpro:IPR042231|mint:Q924X2|reactome:R-MMU-200425|reactome:R-MMU-5362517 - - comment:mint figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:bQd41WfHTVbWLXeyHCxJwWpqR8010090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q91WS0 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8329075|uniprotkb:Q3V2I3|uniprotkb:Q8WUQ5|intact:MINT-1865788|ensembl:ENSMUSP00000043559 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:cisd1_mouse(display_long)|uniprotkb:Cisd1(gene name)|psi-mi:Cisd1(display_short)|uniprotkb:D10Ertd214e(gene name synonym)|uniprotkb:Zcd1(gene name synonym)|uniprotkb:MitoNEET(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_598768.1|ensembl:ENSMUSG00000037710(gene)|ensembl:ENSMUST00000045887(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR018967|interpro:IPR019610|interpro:IPR042216|mint:Q91WS0 - - function:Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions|comment:mint figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:qPVvAeKKeddx0tbECta11rYhntA10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q08857 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8346984|intact:MINT-4090233|ensembl:ENSMUSP00000080974|ensembl:ENSMUSP00000126300|ensembl:ENSMUSP00000131832|ensembl:ENSMUSP00000133008|ensembl:ENSMUSP00000143061 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:cd36_mouse(display_long)|uniprotkb:Cd36(gene name)|psi-mi:Cd36(display_short)|uniprotkb:Platelet glycoprotein IV(gene name synonym)|uniprotkb:PAS IV(gene name synonym)|uniprotkb:PAS-4(gene name synonym)|uniprotkb:Glycoprotein IIIb(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_031669.3|refseq:NP_001153028.1|refseq:NP_001153030.1|refseq:NP_001153027.1|refseq:NP_001153029.1|refseq:XP_006535683.1|refseq:XP_006535684.1|refseq:XP_006535685.1|refseq:XP_006535686.1|refseq:XP_006535687.1|refseq:XP_006535688.1|ensembl:ENSMUSG00000002944(gene)|ensembl:ENSMUST00000082367(transcript)|ensembl:ENSMUST00000165232(transcript)|ensembl:ENSMUST00000169095(transcript)|ensembl:ENSMUST00000170051(transcript)|ensembl:ENSMUST00000197890(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015636"(short-chain fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0015912"(short-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019915"(lipid storage)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031526"(brush border membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033993"(response to lipid)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070508"(cholesterol import)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0070543"(response to linoleic acid)|go:"GO:0070892"(lipoteichoic acid immune receptor activity)|go:"GO:0071221"(cellular response to bacterial lipopeptide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090208"(positive regulation of triglyceride metabolic process)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098900"(regulation of action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:0150024"(oxidised low-density lipoprotein particle clearance)|go:"GO:0150025"(oxidised low-density lipoprotein particle receptor activity)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990379"(lipid transport across blood-brain barrier)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:2000334"(positive regulation of blood microparticle formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|interpro:IPR033076|mint:Q08857|reactome:R-MMU-114608|reactome:R-MMU-1236973|reactome:R-MMU-3000471|reactome:R-MMU-434313|reactome:R-MMU-5686938|reactome:R-MMU-6798695 - - comment:mint|function:Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:QDA1b0VEcVscBQlyYDRxFZMeAtg10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9JLZ3 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-8345249|uniprotkb:Q8QZS0|intact:MINT-1861987|uniprotkb:Q80YD7|uniprotkb:Q9CY78|uniprotkb:Q9D155 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:auhm_mouse(display_long)|uniprotkb:Itaconyl-CoA hydratase(gene name synonym)|uniprotkb:Auh(gene name)|psi-mi:Auh(display_short)|uniprotkb:AU-specific RNA-binding enoyl-CoA hydratase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_057918.2|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:Q9JLZ3|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0004490"(methylglutaconyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0050011"(itaconyl-CoA hydratase activity)|reactome:R-MMU-70895|interpro:IPR001753(Crotonase, core) - - comment:mint|function:Catalyzes the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA. Has very low enoyl-CoA hydratase activity. Was originally identified as RNA-binding protein that binds in vitro to clustered 5'-AUUUA-3' motifs figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:jb9Xjp4DtGg5cI4jv2hmjaydamk10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P20152 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid://GDvGAXOR4hUXNtVpnZefex5v410090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q64727 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-432047|uniprotkb:Q8BP32|uniprotkb:Q8BS46|uniprotkb:Q922C5|uniprotkb:Q922D9|ensembl:ENSMUSP00000022369 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:vinc_mouse(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:Vcl(gene name)|psi-mi:Vcl(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_033528.3|ensembl:ENSMUSG00000021823(gene)|ensembl:ENSMUST00000022369(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0048675"(axon extension)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:Q64727|rcsb pdb:5Y04|reactome:R-MMU-114608|reactome:R-MMU-445355|reactome:R-MMU-5674135|reactome:R-MMU-6798695 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:bfHsrHTLESS6CIctYpg0yX3N+UA10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9CQ69 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-1219646|ensembl:ENSMUSP00000053145|ensembl:ENSMUSP00000104649 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:qcr8_mouse(display_long)|uniprotkb:Uqcrq(gene name)|psi-mi:Uqcrq(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 9.5 kDa protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_079628.1|refseq:NP_001313543.1|ensembl:ENSMUSG00000044894(gene)|ensembl:ENSMUST00000061326(transcript)|ensembl:ENSMUST00000109021(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0021539"(subthalamus development)|go:"GO:0021548"(pons development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030901"(midbrain development)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004205(UcrQ)|interpro:IPR036642|mint:Q9CQ69|reactome:R-MMU-611105 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:D31g2yr7auK53pPni0uZ10drZrY10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P99028 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-1219633|uniprotkb:Q542K2|uniprotkb:Q9CQP4|ensembl:ENSMUSP00000077744 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:qcr6_mouse(display_long)|uniprotkb:Uqcrh(gene name)|psi-mi:Uqcrh(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase complex 11 kDa protein(gene name synonym)|uniprotkb:Cytochrome c1 non-heme 11 kDa protein(gene name synonym)|uniprotkb:Mitochondrial hinge protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_079917.1|ensembl:ENSMUSG00000063882(gene)|ensembl:ENSMUST00000078676(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0009060"(aerobic respiration)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR003422(Ubiquinol-cytochrome C reductase hinge)|interpro:IPR023184|interpro:IPR036811|mint:P99028|reactome:R-MMU-611105 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:AXuswINFjqPM6vssKILEZQw+i8s10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P19123 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-299247|ensembl:ENSMUSP00000131991 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:tnnc1_mouse(display_long)|uniprotkb:Tnnc1(gene name)|psi-mi:Tnnc1(display_short)|uniprotkb:Tncc(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000091898(gene)|ensembl:ENSMUST00000169169(transcript)|go:"GO:0002086"(diaphragm contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005861"(troponin complex)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0010038"(response to metal ion)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0031013"(troponin I binding)|go:"GO:0031014"(troponin T binding)|go:"GO:0032972"(regulation of muscle filament sliding speed)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P19123|rcsb pdb:6KLT|rcsb pdb:6KLU|reactome:R-MMU-390522|go:"GO:0043292"(contractile fiber)|refseq:NP_033419.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:sxUY0VTOyvGAvAbm1MDahk7Ejd010090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q8BUY5 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-15184346|ensembl:ENSMUSP00000002925|uniprotkb:Q99LS9|uniprotkb:Q9CSI1 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:tidc1_mouse(display_long)|uniprotkb:Timmdc1(gene name)|psi-mi:Timmdc1(display_short)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000002846(gene)|ensembl:ENSMUST00000002925(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-MMU-6799198|refseq:NP_077235.2 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:THOEVzYtouOPbcrl9zsHCdIAEWg10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q62261 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P16546 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-911063|uniprotkb:A3KGU6|uniprotkb:Q8K380|uniprotkb:Q9CT05|uniprotkb:A3KGU8|ensembl:ENSMUSP00000092697 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:sptn1_mouse(display_long)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 dip:DIP-37712N|ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000095083(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16546|reactome:R-MMU-264870|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:UVB6Kv+PBlqDH3OLoGjxm5oYVPQ10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P51881 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-445370|uniprotkb:Q61311|ensembl:ENSMUSP00000016463 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:adt2_mouse(display_long)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:Slc25a5(gene name)|psi-mi:Slc25a5(display_short)|uniprotkb:Ant2(gene name synonym)|uniprotkb:Aac2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_031477.1|dip:DIP-31399N|ensembl:ENSMUSG00000016319(gene)|ensembl:ENSMUST00000016463(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P51881|reactome:R-MMU-83936|go:"GO:0031625"(ubiquitin protein ligase binding) - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:146+I0bORlUf6z9chvmdXwUCtOs10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9Z2Z6 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-9989063|uniprotkb:Q3U801|ensembl:ENSMUSP00000035222 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mcat_mouse(display_long)|uniprotkb:Slc25a20(gene name)|psi-mi:Slc25a20(display_short)|uniprotkb:Cac(gene name synonym)|uniprotkb:Cact(gene name synonym)|uniprotkb:Carnitine/acylcarnitine translocase(gene name synonym)|uniprotkb:Solute carrier family 25 member 20(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_065266.1|interpro:IPR023395|reactome:R-MMU-200425|interpro:IPR018108|ensembl:ENSMUSG00000032602(gene)|ensembl:ENSMUST00000035222(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015227"(acyl carnitine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902603"(carnitine transmembrane transport) - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:RX+Mbe4nGGozTzodiev81QsW3JM10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q8BH59 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-445380|uniprotkb:A2BFG0|ensembl:ENSMUSP00000122103 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:cmc1_mouse(display_long)|uniprotkb:Solute carrier family 25 member 12(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 1(gene name synonym)|uniprotkb:Slc25a12(gene name)|psi-mi:Slc25a12(display_short)|uniprotkb:Aralar1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_766024.1|ensembl:ENSMUSG00000027010(gene)|ensembl:ENSMUST00000151937(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0051592"(response to calcium ion)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:Q8BH59|reactome:R-MMU-70263|reactome:R-MMU-8963693 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:n5EwQVcmGB37DOgF1haZb8kCnqc10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q8BGH2 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934811|ensembl:ENSMUSP00000023071|uniprotkb:Q3TIL3|uniprotkb:Q3TTG7|uniprotkb:Q3TWD3 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:sam50_mouse(display_long)|uniprotkb:Samm50(gene name)|psi-mi:Samm50(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000022437(gene)|ensembl:ENSMUST00000023071(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q8BGH2|reactome:R-MMU-9013404|refseq:NP_848729.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:OWxecVBGU7/ayT7jqSrqeKmr5fw10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P67778 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-298507|uniprotkb:P24142|uniprotkb:Q3UB75|uniprotkb:Q5SQG4|ensembl:ENSMUSP00000119603 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:phb_mouse(display_long)|uniprotkb:Phb(gene name)|psi-mi:Phb(display_short)|uniprotkb:B-cell receptor-associated protein 32(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000038845(gene)|ensembl:ENSMUST00000125172(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045471"(response to ethanol)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P67778|reactome:R-MMU-5673000|reactome:R-MMU-8949664|refseq:NP_032857.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:eUStcZ9Mu7+7MHr/GJXFwwJY/Fc10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P58281 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-776163|uniprotkb:Q3ULA5|uniprotkb:Q8BKU7|uniprotkb:Q8BLL3|uniprotkb:Q8BM08|uniprotkb:Q8R3J7|uniprotkb:A6H6Q3|ensembl:ENSMUSP00000124223 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:opa1_mouse(display_long)|uniprotkb:Optic atrophy protein 1 homolog(gene name synonym)|uniprotkb:Large GTP-binding protein(gene name synonym)|uniprotkb:Opa1(gene name)|psi-mi:Opa1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_598513.1|refseq:XP_006522720.1|ensembl:ENSMUSG00000038084(gene)|ensembl:ENSMUST00000160597(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001843"(neural tube closure)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007601"(visual perception)|go:"GO:0008017"(microtubule binding)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030425"(dendrite)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090102"(cochlea development)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090398"(cellular senescence)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904643"(response to curcumin)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR033047|mint:P58281|reactome:R-MMU-169911 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:cj1HZs8CYUuCBy4KhYmtO/lvmUk10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:E9Q7L0 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-15184326|ensembl:ENSMUSP00000022480 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:e9q7l0_mouse(display_long)|uniprotkb:Ogdhl(gene name)|psi-mi:Ogdhl(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000021913(gene)|ensembl:ENSMUST00000022480(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|refseq:NP_001074599.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:BFiHQ4NgGhTDKEc9h5rXFaZWYx810090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q60597 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-773541|uniprotkb:Q3UDM7|uniprotkb:Q5DTI4|uniprotkb:Q5SVX7|uniprotkb:Q5SVX9|uniprotkb:Q6PFZ2|uniprotkb:Q80Y57|uniprotkb:Q8K0K7|uniprotkb:Q8K2Z3|uniprotkb:Q8R3M2|uniprotkb:Q91WP2|ensembl:ENSMUSP00000003461|ensembl:ENSMUSP00000099090 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:odo1_mouse(display_long)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:Ogdh(gene name)|psi-mi:Ogdh(display_short)|uniprotkb:Kiaa4192(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_035086.2|refseq:XP_006514645.1|refseq:XP_006514646.1|refseq:XP_006514647.1|refseq:XP_006514648.1|refseq:NP_001239211.1|refseq:NP_001239212.1|refseq:NP_001239216.1|refseq:NP_001239217.1|refseq:XP_017169826.1|ensembl:ENSMUSG00000020456(gene)|ensembl:ENSMUST00000003461(transcript)|ensembl:ENSMUST00000101554(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q60597|rcsb pdb:3E2H|rcsb pdb:3TF7|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:6as/Sp5FTXpjU1BwjR7vJ6xcxuA10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q61941 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-15184302|uniprotkb:Q9JK70 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:nntm_mouse(display_long)|uniprotkb:Nnt(gene name)|psi-mi:Nnt(display_short)|uniprotkb:Nicotinamide nucleotide transhydrogenase(gene name synonym)|uniprotkb:Pyridine nucleotide transhydrogenase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 reactome:R-MMU-71403|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0008746"("NAD(P)+ transhydrogenase activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0050661"(NADP binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0051287"(NAD binding)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR029035|interpro:IPR026255|interpro:IPR024605|interpro:IPR034300|interpro:IPR036291 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:Seas/Iqob55Q1juwFSGIZt/hqXs10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P10493 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-1032117|uniprotkb:Q8BQI3|uniprotkb:Q8C3U8|uniprotkb:Q8C9P6|uniprotkb:Q3TKX9|ensembl:ENSMUSP00000005532 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:nid1_mouse(display_long)|uniprotkb:Nid1(gene name)|psi-mi:Nid1(display_short)|uniprotkb:Ent(gene name synonym)|uniprotkb:Entactin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_035047.2|interpro:IPR026823|interpro:IPR036857|mint:P10493|rcsb pdb:1GL4|rcsb pdb:1H4U|rcsb pdb:1NPE|reactome:R-MMU-1474228|reactome:R-MMU-3000157|ensembl:ENSMUSG00000005397(gene)|ensembl:ENSMUST00000005532(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071944"(cell periphery)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:3dnqHnqAO3PlU6v5pchyqrF4UBg10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9CQ54 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934494|ensembl:ENSMUSP00000032882|uniprotkb:Q3TLB2 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:nduc2_mouse(display_long)|uniprotkb:Ndufc2(gene name)|psi-mi:Ndufc2(display_short)|uniprotkb:Complex I-B14.5b(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5b(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000030647(gene)|ensembl:ENSMUST00000032882(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060547"(negative regulation of necrotic cell death)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR009423(NADH-ubiquinone oxidoreductase subunit b14.5b)|mint:Q9CQ54|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6798695|reactome:R-MMU-6799198|rcsb pdb:6ZR2|refseq:NP_077182.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:RYKiU7/XvDvMH95qPPT8GLPyogg10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9CQJ8 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934511|ensembl:ENSMUSP00000022980 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:ndub9_mouse(display_long)|uniprotkb:Ndufb9(gene name)|psi-mi:Ndufb9(display_short)|uniprotkb:Complex I-B22(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B22 subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000022354(gene)|ensembl:ENSMUST00000022980(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR033034|mint:Q9CQJ8|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_075661.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:GW+ZRnFBsEKtXPd0+wFJZRVrQ4A10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9D6J5 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934391|ensembl:ENSMUSP00000026222|uniprotkb:Q9D6M7 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:ndub8_mouse(display_long)|uniprotkb:Ndufb8(gene name)|psi-mi:Ndufb8(display_short)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000025204(gene)|ensembl:ENSMUST00000026222(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|mint:Q9D6J5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-1268020|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_080337.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:haHI1mKizIPRzFQxhFoJShL4eO410090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q3UIU2 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934427|ensembl:ENSMUSP00000092746 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:ndub6_mouse(display_long)|uniprotkb:Ndufb6(gene name)|psi-mi:Ndufb6(display_short)|uniprotkb:Gm137(gene name synonym)|uniprotkb:Complex I-B17(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B17 subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000071014(gene)|ensembl:ENSMUST00000095128(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR019174|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|mint:Q3UIU2|refseq:NP_001028477.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:FIprQvG6ZL1DDoxrJvYTkzz/ei810090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9CQH3 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934537|ensembl:ENSMUSP00000114963 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:ndub5_mouse(display_long)|uniprotkb:Ndufb5(gene name)|psi-mi:Ndufb5(display_short)|uniprotkb:Complex I-SGDH(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase SGDH subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000027673(gene)|ensembl:ENSMUST00000127477(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019173|mint:Q9CQH3|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|rcsb pdb:6ZTQ|refseq:NP_079592.2 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:4uKYAyCAmfXZr34JQcuTyjoVhA810090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9CQZ6 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934375|ensembl:ENSMUSP00000027193|uniprotkb:Q3UUR9 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:ndub3_mouse(display_long)|uniprotkb:Ndufb3(gene name)|psi-mi:Ndufb3(display_short)|uniprotkb:Complex I-B12(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B12 subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000026032(gene)|ensembl:ENSMUST00000027193(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0022900"(electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012576(NADH-ubiquinone oxidoreductase B12 subunit)|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_079873.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:hhTBowxrL0XlFp2QYPplJGtZ11A10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:O09111 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934342|ensembl:ENSMUSP00000112320 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:ndubb_mouse(display_long)|uniprotkb:Ndufb11(gene name)|psi-mi:Ndufb11(display_short)|uniprotkb:Np15(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Neuronal protein 15.6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000031059(gene)|ensembl:ENSMUST00000116621(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_062308.2|refseq:XP_006527617.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:cKVP1YOTOsAs19j2cWCExm7tK4w10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9D8B4 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934254 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:nduab_mouse(display_long)|uniprotkb:Ndufa11(gene name)|psi-mi:Ndufa11(display_short)|uniprotkb:Complex I-B14.7(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|reactome:R-MMU-611105|reactome:R-MMU-6799198|interpro:IPR039205|mint:Q9D8B4 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:rRH3p7YRf7303bbBLOiM99HGnSM10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:O88441 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-775894|ensembl:ENSMUSP00000028511|uniprotkb:Q3TFR2 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mtx2_mouse(display_long)|uniprotkb:Mtx2(gene name)|psi-mi:Mtx2(display_short)|uniprotkb:MNCb-0780(orf name)|uniprotkb:Mitochondrial outer membrane import complex protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000027099(gene)|ensembl:ENSMUST00000028511(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0015031"(protein transport)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:O88441|refseq:NP_058084.3 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:uODpL/j0VXAZ6jJINeggCV1nmLM10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9CRB8 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-15184285|ensembl:ENSMUSP00000004868|uniprotkb:Q9CZX4 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mtfp1_mouse(display_long)|uniprotkb:Mtfp1(gene name)|psi-mi:Mtfp1(display_short)|uniprotkb:Mtp18(gene name synonym)|uniprotkb:Mitochondrial 18 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000004748(gene)|ensembl:ENSMUST00000004868(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019560|refseq:NP_080719.2 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:vJQ48EKpeqAWP1RMj86lKg0sikc10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q791V5 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-775885|ensembl:ENSMUSP00000121851|uniprotkb:Q3TPS5|uniprotkb:Q99LZ6|uniprotkb:Q9D060|uniprotkb:Q9D7Y2|uniprotkb:Q9QZP3 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mtch2_mouse(display_long)|uniprotkb:Mtch2(gene name)|psi-mi:Mtch2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071478"(cellular response to radiation)|go:"GO:0090152"(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|ensembl:ENSMUSG00000027282(gene)|ensembl:ENSMUST00000136872(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR018108|interpro:IPR023395|mint:Q791V5|refseq:NP_062732.1|refseq:NP_001304170.1|refseq:NP_001304171.1|refseq:NP_001304172.1|refseq:NP_001304173.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:5TT13uYcx21wiKjuQc4tynZ31Ac10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P03921 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934302|ensembl:ENSMUSP00000081001 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:nu5m_mouse(display_long)|uniprotkb:Mtnd5(gene name)|psi-mi:Mtnd5(display_short)|uniprotkb:mt-Nd5(gene name synonym)|uniprotkb:Nd5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000064367(gene)|ensembl:ENSMUST00000082418(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_904338.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:G3qWFDgm7vKqOv/r4bLz/Bayw2s10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P03911 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934562|ensembl:ENSMUSP00000081000 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:nu4m_mouse(display_long)|uniprotkb:Mtnd4(gene name)|psi-mi:Mtnd4(display_short)|uniprotkb:mt-Nd4(gene name synonym)|uniprotkb:Nd4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|go:"GO:0021549"(cerebellum development)|reactome:R-MMU-611105|reactome:R-MMU-6799198|ensembl:ENSMUSG00000064363(gene)|ensembl:ENSMUST00000082414(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|refseq:NP_904337.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:WRCNqlPCKDHbK0/8yYNaICAGjgE10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P03888 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934268|ensembl:ENSMUSP00000080991|uniprotkb:Q9G0S6 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:nu1m_mouse(display_long)|uniprotkb:Mtnd1(gene name)|psi-mi:Mtnd1(display_short)|uniprotkb:mt-Nd1(gene name synonym)|uniprotkb:Nd1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000064341(gene)|ensembl:ENSMUST00000082392(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|go:"GO:0005747"(mitochondrial respiratory chain complex I)|rcsb pdb:7AK5|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|rcsb pdb:7AK6|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|rcsb pdb:7B93|go:"GO:0009060"(aerobic respiration)|go:"GO:0030425"(dendrite)|reactome:R-MMU-611105|reactome:R-MMU-6799198|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|rcsb pdb:6G2J|refseq:NP_904328.1|dip:DIP-61655N|refseq:YP_220550.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:SjMJxcFumymfyBPEXpxDC6Sq6V410090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9DB15 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-6396530|ensembl:ENSMUSP00000044417|uniprotkb:B1ATZ3|uniprotkb:Q3TKJ3|uniprotkb:Q99JS8 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:rm12_mouse(display_long)|uniprotkb:Mrpl12(gene name)|psi-mi:Mrpl12(display_short)|uniprotkb:Rpml12(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000039640(gene)|ensembl:ENSMUST00000043627(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006412"(translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000206(Ribosomal protein L7/L12)|interpro:IPR008932(Ribosomal protein L7/L12, oligomerisation)|interpro:IPR013823(Ribosomal protein L7/L12, C-terminal)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036235|mint:Q9DB15|reactome:R-MMU-5389840|reactome:R-MMU-5419276|refseq:NP_081480.2 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:n6RpvpiZ9QPSvpdPetbaKK+4F3Y10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9D023 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2693979|uniprotkb:Q3UA44|ensembl:ENSMUSP00000027853 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mpc2_mouse(display_long)|uniprotkb:Mpc2(gene name)|psi-mi:Mpc2(display_short)|uniprotkb:Brain protein 44(gene name synonym)|uniprotkb:Brp44(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_081706.1|ensembl:ENSMUSG00000026568(gene)|ensembl:ENSMUST00000027853(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006850"(mitochondrial pyruvate transmembrane transport)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR005336(Protein of unknown function UPF0041)|mint:Q9D023|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus) - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:PDFMxMPgkUM9G0QKud00Lk/kors10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q78IK4 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-12523754|ensembl:ENSMUSP00000026599 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mic27_mouse(display_long)|uniprotkb:Apolipoprotein O-like(gene name synonym)|uniprotkb:Protein FAM121A(gene name synonym)|uniprotkb:Apool(gene name)|psi-mi:Apool(display_short)|uniprotkb:Fam121a(gene name synonym)|uniprotkb:Mic27(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000025525(gene)|ensembl:ENSMUST00000026599(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|interpro:IPR019166|interpro:IPR033182|reactome:R-MMU-114608|refseq:NP_080841.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:EwRruXYRyPfcpKL+Yv7brXT9fMk10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q3ULD5 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-6877475|ensembl:ENSMUSP00000022148|uniprotkb:Q3UPS6 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mccb_mouse(display_long)|uniprotkb:Mccc2(gene name)|psi-mi:Mccc2(display_short)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000021646(gene)|ensembl:ENSMUST00000022148(transcript)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q3ULD5|reactome:R-MMU-196780|reactome:R-MMU-70895|refseq:NP_084302.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:0q4wsAWb+zqTRNjZnCPoNabUrbA10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q99MR8 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-773469|uniprotkb:Q3TGU0|uniprotkb:Q9D8R2|ensembl:ENSMUSP00000029259 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mcca_mouse(display_long)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym)|uniprotkb:Mccc1(gene name)|psi-mi:Mccc1(display_short)|uniprotkb:Mcca(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_076133.3|ensembl:ENSMUSG00000027709(gene)|ensembl:ENSMUST00000029259(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q99MR8|reactome:R-MMU-196780|reactome:R-MMU-70895 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:SziuYdcOx+maKy71pNxoKql1HGI10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q60675 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-9249198|uniprotkb:F8VQ43|uniprotkb:Q05003|uniprotkb:Q64061|ensembl:ENSMUSP00000090304 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:lama2_mouse(display_long)|uniprotkb:Lama2(gene name)|psi-mi:Lama2(display_short)|uniprotkb:Laminin M chain(gene name synonym)|uniprotkb:Laminin-12 subunit alpha(gene name synonym)|uniprotkb:Laminin-2 subunit alpha(gene name synonym)|uniprotkb:Laminin-4 subunit alpha(gene name synonym)|uniprotkb:Merosin heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_032507.2|ensembl:ENSMUSG00000019899(gene)|ensembl:ENSMUST00000092639(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0042383"(sarcolemma)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043197"(dendritic spine)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:1DYK|rcsb pdb:1OKQ|rcsb pdb:1QU0|rcsb pdb:2WJS|rcsb pdb:5IK4|rcsb pdb:5IK5|rcsb pdb:5IK7|rcsb pdb:5IK8|reactome:R-MMU-3000157|reactome:R-MMU-8874081 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:FAUu0eiyQrZzU3Eww7OpJmNCm2s10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q05793 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-1032089 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:pgbm_mouse(display_long)|uniprotkb:Hspg2(gene name)|psi-mi:Hspg2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_032331.2|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR000034(Laminin B)|interpro:IPR001791(Laminin G)|interpro:IPR000082(SEA)|interpro:IPR023415|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002020"(protease binding)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|rcsb pdb:1GL4|reactome:R-MMU-1474228|reactome:R-MMU-1971475|reactome:R-MMU-2022928|reactome:R-MMU-2024096|reactome:R-MMU-216083|reactome:R-MMU-3000157|reactome:R-MMU-3000171|reactome:R-MMU-3000178|reactome:R-MMU-975634|mint:Q05793|interpro:IPR036055|interpro:IPR036179 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:cSZXdrVzYrrPDxo2+9QWAlImMbQ10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:P63017 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9EQP2 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-491022|ensembl:ENSMUSP00000028755 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:ehd4_mouse(display_long)|uniprotkb:Ehd4(gene name)|psi-mi:Ehd4(display_short)|uniprotkb:Past2(gene name synonym)|uniprotkb:PAST homolog 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_598599.2|ensembl:ENSMUSG00000027293(gene)|ensembl:ENSMUST00000028755(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|interpro:IPR031692|interpro:IPR040990|mint:Q9EQP2|rcsb pdb:5MTV|rcsb pdb:5MVF|interpro:IPR030381|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:Amxin/3NzINpV4SP1xvRjstQAG010090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9D2G2 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-773210|uniprotkb:Q3UEA0|uniprotkb:Q4FK55|uniprotkb:Q8CIE8|ensembl:ENSMUSP00000060346|ensembl:ENSMUSP00000152664 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:odo2_mouse(display_long)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:Dlst(gene name)|psi-mi:Dlst(display_short)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_084501.1|ensembl:ENSMUSG00000004789(gene)|ensembl:ENSMUST00000053811(transcript)|ensembl:ENSMUST00000221357(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:Q9D2G2|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:jyBoApRkfA3STOc5qJ01/cE2UHU10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:O08749 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-773199|uniprotkb:Q3TG55|uniprotkb:Q3U5W5|uniprotkb:Q3UWP7|uniprotkb:Q99LD3|ensembl:ENSMUSP00000106481 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:dldh_mouse(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_031887.2|ensembl:ENSMUSG00000020664(gene)|ensembl:ENSMUST00000110857(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043209"(myelin sheath)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:O08749|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-6783984|reactome:R-MMU-70268|reactome:R-MMU-70895|reactome:R-MMU-71064|reactome:R-MMU-71403 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:6j/8rw4lkNMW4Lo5sGoRdDJBk2w10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9DCT8 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-299831|ensembl:ENSMUSP00000081943 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:crip2_mouse(display_long)|uniprotkb:Crip2(gene name)|psi-mi:Crip2(display_short)|uniprotkb:Crp2(gene name synonym)|uniprotkb:Hlp(gene name synonym)|uniprotkb:Heart LIM protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000006356(gene)|ensembl:ENSMUST00000084882(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q9DCT8|refseq:NP_077185.1|refseq:NP_001334372.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:gUnIigpt1aCOrC+PyGxN8bBdGZs10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q61387 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2934706|ensembl:ENSMUSP00000025095 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:cox7r_mouse(display_long)|uniprotkb:Cox7a2l(gene name)|psi-mi:Cox7a2l(display_short)|uniprotkb:Cox7rp(gene name synonym)|uniprotkb:Silg81(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIIa-related protein(gene name synonym)|uniprotkb:Silica-induced gene 81 protein(gene name synonym)|uniprotkb:Scaf1(gene name synonym)|uniprotkb:Supercomplex assembly factor I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000024248(gene)|ensembl:ENSMUST00000025095(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR017267(Cytochrome c oxidase subunit VIIa-related, mitochondrial)|interpro:IPR036539|interpro:IPR039297|mint:Q61387|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|refseq:NP_033213.1 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:iVm8ROGd/MyFLzBoOWPty00w2bg10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:O35658 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-642072 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:c1qbp_mouse(display_long)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:GC1q-R protein(gene name synonym)|uniprotkb:C1qbp(gene name)|psi-mi:C1qbp(display_short)|uniprotkb:Gc1qbp(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 reactome:R-MMU-140837|reactome:R-MMU-8980692|reactome:R-MMU-9013106|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|dip:DIP-32249N - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:tPoLimqgF2SXeVXk7Z5rCQa+wTc10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9CPQ8 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-2693989|uniprotkb:O70590|uniprotkb:Q5M9M8|ensembl:ENSMUSP00000047960 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:atp5l_mouse(display_long)|uniprotkb:Atp5mg(gene name)|psi-mi:Atp5mg(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:Atp5l(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_038823.2|ensembl:ENSMUSG00000038717(gene)|ensembl:ENSMUST00000043675(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046034"(ATP metabolic process)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:Q9CPQ8|reactome:R-MMU-163210|reactome:R-MMU-8949613 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:s3+OFey5QI8KQrM9GR7FAHoFlJY10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q06185 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-6666496|ensembl:ENSMUSP00000051222|uniprotkb:P70342 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:atp5i_mouse(display_long)|uniprotkb:Atp5me(gene name)|psi-mi:Atp5me(display_short)|uniprotkb:Atp5i(gene name synonym)|uniprotkb:Atp5k(gene name synonym)|uniprotkb:Lfm-1(gene name synonym)|uniprotkb:Lfm1(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:Q06185|reactome:R-MMU-163210|reactome:R-MMU-8949613|ensembl:ENSMUSG00000050856(gene)|ensembl:ENSMUST00000049628(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|refseq:NP_031533.2 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:1hl0GhfM23wEB+OjR4PbmxMdNnQ10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9DCZ4 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-15184249|ensembl:ENSMUSP00000109531|uniprotkb:B1ASQ2|uniprotkb:B1ASQ3|uniprotkb:Q9D186 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:mic26_mouse(display_long)|uniprotkb:Apoo(gene name)|psi-mi:Apoo(display_short)|uniprotkb:Fam121b(gene name synonym)|uniprotkb:Mic23(gene name synonym)|uniprotkb:Mic26(gene name synonym)|uniprotkb:Apolipoprotein O(gene name synonym)|uniprotkb:MICOS complex subunit Mic23(gene name synonym)|uniprotkb:Protein FAM121B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000079508(gene)|ensembl:ENSMUST00000113898(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|interpro:IPR019166|interpro:IPR033182|mint:Q9DCZ4|refseq:NP_001186266.1|refseq:NP_001186267.1|refseq:NP_001186268.1|refseq:NP_080949.2 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:0NV9wpCn9c3f3hHnU2v/emb2IMI10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:O54774 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-775247|ensembl:ENSMUSP00000020420 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:ap3d1_mouse(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:Ap3d1(gene name)|psi-mi:Ap3d1(display_short)|uniprotkb:Ap3d(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_031486.1|dip:DIP-32163N|ensembl:ENSMUSG00000020198(gene)|ensembl:ENSMUST00000020420(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030424"(axon)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O54774 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:q83u6ORB4zYNuQihE4PI1rhvSkY10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q9Z0X1 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-773597|intact:EBI-4282542|uniprotkb:Q1L6K5|ensembl:ENSMUSP00000041104 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:aifm1_mouse(display_long)|uniprotkb:Programmed cell death protein 8(gene name synonym)|uniprotkb:Aifm1(gene name)|psi-mi:Aifm1(display_short)|uniprotkb:Aif(gene name synonym)|uniprotkb:Pdcd8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_001277293.1|refseq:NP_036149.1|ensembl:ENSMUSG00000036932(gene)|ensembl:ENSMUST00000037349(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004174"(electron-transferring-flavoprotein dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:Q9Z0X1|rcsb pdb:1GV4|rcsb pdb:3GD3|rcsb pdb:3GD4|rcsb pdb:5MIU|rcsb pdb:5MIV - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:c0oYNXW1lpmieqgWc4TZra/RJNk10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:Q7TPR4 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-774010|ensembl:ENSMUSP00000021554 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:actn1_mouse(display_long)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)|uniprotkb:Actn1(gene name)|psi-mi:Actn1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_598917.1|ensembl:ENSMUSG00000015143(gene)|ensembl:ENSMUST00000021554(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030054"(cell junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0032127"(dense core granule membrane)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:Q7TPR4|rcsb pdb:6C0A|reactome:R-MMU-114608|reactome:R-MMU-446388|reactome:R-MMU-9013405|reactome:R-MMU-9013418|reactome:R-MMU-9035034 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:02QPrtqpFY8sgQvjRRI5wmCbNjU10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16082 uniprotkb:D3Z2B3 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-15186316|ensembl:ENSMUSP00000107406 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:d3z2b3_mouse(display_long)|uniprotkb:Acad12(gene name)|psi-mi:Acad12(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSMUSG00000042647(gene)|ensembl:ENSMUST00000111776(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR037069 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:LgNCel3AXdwx/d3TWjkdZzPzMqE10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16082 uniprotkb:P70670 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-647147|uniprotkb:E9QMB1|ensembl:ENSMUSP00000089680 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:nacam_mouse(display_long)|uniprotkb:Gm1878(gene name synonym)|uniprotkb:Alpha-NAC, muscle-specific form(gene name synonym)|uniprotkb:Naca(gene name)|psi-mi:Naca(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15182189|imex:IM-25814-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_001106670.1|refseq:NP_038636.2|ensembl:ENSMUSG00000061315(gene)|ensembl:ENSMUST00000092048(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051451"(myoblast migration)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:P70670 - - - figure legend:table 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2017/06/15 2017/06/23 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:4QZh6JIwWgCTyZyvNxj5mmR6Bps10090 rigid:f5rscYfU6QWZZt3mGZHstkTpyPg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5BJH1 uniprotkb:P02511 intact:EBI-15105920|ensembl:ENSP00000480857 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:q5bjh1_human(display_long)|uniprotkb:PSAP(gene name)|psi-mi:PSAP(display_short) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187574|imex:IM-25814-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197746(gene)|ensembl:ENST00000610929(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0006665"(sphingolipid metabolic process)|interpro:IPR003119(Saposin type A)|interpro:IPR007856(Saposin-like type B, 1)|interpro:IPR008138(Saposin-like type B, 2)|interpro:IPR008139(Saposin B)|interpro:IPR008373(Saposin)|interpro:IPR011001(Saposin-like) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N - - crc64:AE08BED46B7849CB figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:OphVJtCbJSLtX30yoLHZVePKcY89606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:KOj82JFVQuOGUyzqFtLvTQfMDyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16082 uniprotkb:Q5BJH1 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-15105920|ensembl:ENSP00000480857 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:q5bjh1_human(display_long)|uniprotkb:PSAP(gene name)|psi-mi:PSAP(display_short) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187583|imex:IM-25814-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSG00000197746(gene)|ensembl:ENST00000610929(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0006665"(sphingolipid metabolic process)|interpro:IPR003119(Saposin type A)|interpro:IPR007856(Saposin-like type B, 1)|interpro:IPR008138(Saposin-like type B, 2)|interpro:IPR008139(Saposin B)|interpro:IPR008373(Saposin)|interpro:IPR011001(Saposin-like) - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:OphVJtCbJSLtX30yoLHZVePKcY89606 rigid:NglHcL0n/vG9T4wW0guf/gT/edY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16082 uniprotkb:P04075 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187591|imex:IM-25814-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 rigid:joQeOwY6gKUrJDHUHxctAouJ52E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16082 uniprotkb:P02511 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187595|imex:IM-25814-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N - - crc64:AE08BED46B7849CB figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:uTSG+JnXz+brnfQsiBgort2vO2A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16082 uniprotkb:Q14203 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187599|imex:IM-25814-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rigid:CVESS9l3jDlUN3lVIr29WClGmnQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25705 uniprotkb:Q16082 intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187603|imex:IM-25814-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:2hc6rVYaOvEFgSFAXEg+zbDxlQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13929 uniprotkb:Q16082 intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187607|imex:IM-25814-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:Hw5dtytrXviSVezg1ffizaKq7gA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68104 uniprotkb:Q16082 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187611|imex:IM-25814-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:Kb+LvWOob9bzcyXb29WPxCmALac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13533 uniprotkb:Q16082 intact:EBI-1048066|uniprotkb:Q13943|uniprotkb:Q14906|uniprotkb:Q14907|uniprotkb:A2RTX1|ensembl:ENSP00000386041|uniprotkb:D9YZU2 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:myh6_human(display_long)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym)|uniprotkb:MYH6(gene name)|psi-mi:MYH6(display_short)|uniprotkb:MYHCA(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187615|imex:IM-25814-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002462.2|ensembl:ENSG00000197616(gene)|ensembl:ENST00000405093(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0032982"(myosin filament)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-390522 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:W+Z6SSSLWzCGPSaXQFr+rNuOaB09606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:+uOU/FNx4Sl7PdrqV/2SFD7zGr0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A2VCT2 uniprotkb:Q16082 intact:EBI-15105872 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:a2vct2_human(display_long)|uniprotkb:OGDH(gene name)|psi-mi:OGDH(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187619|imex:IM-25814-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030976"(thiamine pyrophosphate binding)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR005475(Transketolase, central region) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:cs7joFFsTRxep7nM6Qc9mhx60go9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:tcHyg8dcDahq6/4H56K18p0VS24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62913 uniprotkb:Q16082 intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187623|imex:IM-25814-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:KL0KuQStLxioMkX/YjyJWjDjgjw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:D6RFM5 uniprotkb:Q16082 intact:EBI-15105883|ensembl:ENSP00000426514 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:d6rfm5_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187627|imex:IM-25814-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000073578(gene)|ensembl:ENST00000504309(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0022900"(electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|refseq:NP_001317687.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:o0IrqLFiw5VBoNa+S4s7vMtynTQ9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:E4pmGbQwThL+rEmlYrKIcaUOHQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IW09 uniprotkb:Q16082 intact:EBI-15105935 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:q8iw09_human(display_long)|uniprotkb:ZNF335(gene name)|psi-mi:ZNF335(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187631|imex:IM-25814-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071378.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:NtJ0rwdViNRewa9b76KkREk8oVs9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:TNTce8h6y8uqMrQfBqHgR7tX27E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04075 uniprotkb:P02511 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187635|imex:IM-25814-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N - - crc64:AE08BED46B7849CB figure legend:table 3|comment:weak interaction|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:bhEVx1vMXVlztGFN688UmdkQdcI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02511 uniprotkb:P02511 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187639|imex:IM-25814-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N - crc64:AE08BED46B7849CB crc64:AE08BED46B7849CB figure legend:table 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:7aBGHTYzQMx7+hRsyz22EBt6WCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14203 uniprotkb:P02511 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15187643|imex:IM-25814-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N - - crc64:AE08BED46B7849CB figure legend:table 3|comment:weak interaction|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/06/15 2017/06/24 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:gXfhHzT5qcnWKzIu4Y0c5yASBHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75083 uniprotkb:Q16082 intact:EBI-351917|uniprotkb:O75313|uniprotkb:Q8N6E5|uniprotkb:Q9UG05|uniprotkb:Q9UG78|uniprotkb:A8MPU4|uniprotkb:Q9UQE0|uniprotkb:A8K6E9|ensembl:ENSP00000371890|ensembl:ENSP00000427687 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:wdr1_human(display_long)|uniprotkb:WDR1(gene name)|psi-mi:WDR1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)|uniprotkb:NORI-1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487595|imex:IM-25814-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005103.2|refseq:NP_059830.1|ensembl:ENSG00000071127(gene)|ensembl:ENST00000382452(transcript)|ensembl:ENST00000499869(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O75083|reactome:R-HSA-114608 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:ewKq6uA2Wrg/uK31ayOoenA9Gv49606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:9EEoaxn7h0AARKGjvp/sBfsC+Gk false sufficient binding region:221..221-466..466 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P68133 uniprotkb:Q16082 intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487450|imex:IM-25814-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:ymXNZ6kbwI+TItAfxNlrdvL9LFo false sufficient binding region:253-377 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q8WZ42 uniprotkb:Q16082 intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487579|imex:IM-25814-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:sx/nHiRei6rIRkss/DDQFMAdY1o false sufficient binding region:1493-1890 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:O15273 uniprotkb:Q16082 intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487571|imex:IM-25814-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:jKq3PFcG19Yf2a701HEyqvoWg2U false sufficient binding region:92-167 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q92736 uniprotkb:Q16082 intact:EBI-1170425|uniprotkb:Q15411|uniprotkb:Q546N8|uniprotkb:Q5T3P2|ensembl:ENSP00000355533 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:ryr2_human(display_long)|uniprotkb:RYR2(gene name)|psi-mi:RYR2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487563|imex:IM-25814-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026.2|refseq:XP_006711868.1|ensembl:ENSG00000198626(gene)|ensembl:ENST00000366574(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043924"(suramin binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:4JKQ|rcsb pdb:6Y4O|rcsb pdb:6Y4P|rcsb pdb:7KL5|reactome:R-HSA-2672351|reactome:R-HSA-5578775|dip:DIP-38325N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Z3eTbcvvaCLOKWelrdkxMso6IT89606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:EluZ0OJyRxdDcLiiPTGYTV7YlOo false sufficient binding region:1864..1864-2359..2359 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P54296 uniprotkb:Q16082 intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487555|imex:IM-25814-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:SG17gThcCo3XDuEkofiCgNrRSWE false sufficient binding region:1283-1465 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:A5YM51 uniprotkb:Q16082 intact:EBI-15105858 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:a5ym51_human(display_long)|uniprotkb:MYH7(gene name)|psi-mi:MYH7(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487546|imex:IM-25814-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005524"(ATP binding)|go:"GO:0016459"(myosin complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0003774"(cytoskeletal motor activity)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR036961|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR002928(Myosin tail)|interpro:IPR027417|interpro:IPR008989(Myosin S1 fragment, N-terminal) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:1az49rPlMN4GWuXdSRmmoi55fZc9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:HPkQnDHRhVMwfyxoDQcl5ZoXY+E false sufficient binding region:?-? - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P13533 uniprotkb:Q16082 intact:EBI-1048066|uniprotkb:Q13943|uniprotkb:Q14906|uniprotkb:Q14907|uniprotkb:A2RTX1|ensembl:ENSP00000386041|uniprotkb:D9YZU2 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:myh6_human(display_long)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym)|uniprotkb:MYH6(gene name)|psi-mi:MYH6(display_short)|uniprotkb:MYHCA(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487538|imex:IM-25814-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002462.2|ensembl:ENSG00000197616(gene)|ensembl:ENST00000405093(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0032982"(myosin filament)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-390522 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:W+Z6SSSLWzCGPSaXQFr+rNuOaB09606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:+uOU/FNx4Sl7PdrqV/2SFD7zGr0 false sufficient binding region:846-958 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q14896 uniprotkb:Q16082 intact:EBI-704176|uniprotkb:Q16410|uniprotkb:Q6R2F7|uniprotkb:Q9UE27|uniprotkb:A5PL00|uniprotkb:Q9UM53|ensembl:ENSP00000442795 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:mypc3_human(display_long)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)|uniprotkb:MYBPC3(gene name)|psi-mi:MYBPC3(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487530|imex:IM-25814-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000247.2|ensembl:ENSG00000134571(gene)|ensembl:ENST00000545968(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014705"(C zone)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031432"(titin binding)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032971"(regulation of muscle filament sliding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14896|rcsb pdb:1GXE|rcsb pdb:1PD6|rcsb pdb:2AVG|rcsb pdb:2K1M|rcsb pdb:2MQ0|rcsb pdb:2MQ3|rcsb pdb:2V6H|rcsb pdb:3CX2|rcsb pdb:5K6P|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|reactome:R-HSA-390522 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:JYH9WxTpibBvj4Z6y0ZNgQEW2zE9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:NfTfGII3Q8oEQsTniqQ8+Z+SZ6s false sufficient binding region:945-1274 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q14315 uniprotkb:Q16082 intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487522|imex:IM-25814-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:xtFIe1z5fn4H/piGWTx8iptS5Z8 false sufficient binding region:2608-2692 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P13929 uniprotkb:Q16082 intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487514|imex:IM-25814-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:Hw5dtytrXviSVezg1ffizaKq7gA false sufficient binding region:85-434 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q14203 uniprotkb:Q16082 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487506|imex:IM-25814-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:CVESS9l3jDlUN3lVIr29WClGmnQ false sufficient binding region:910-1144 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P21810 uniprotkb:Q16082 intact:EBI-762076|uniprotkb:P13247|uniprotkb:D3DWU3|ensembl:ENSP00000327336 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:pgs1_human(display_long)|uniprotkb:SLRR1A(gene name synonym)|uniprotkb:Bone/cartilage proteoglycan I(gene name synonym)|uniprotkb:PG-S1(gene name synonym)|uniprotkb:BGN(gene name)|psi-mi:BGN(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487498|imex:IM-25814-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001702.1|refseq:XP_016885213.1|ensembl:ENSG00000182492(gene)|ensembl:ENST00000331595(transcript)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0009986"(cell surface)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0030133"(transport vesicle)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042383"(sarcolemma)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060348"(bone development)|go:"GO:0061975"(articular cartilage development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR028547|interpro:IPR032675|mint:P21810|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:G7A6TRMpSIqTBpXtm67XG0GfM2w9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:9TdoUhUux+kyIW+z8hOpjVaQ7HU false sufficient binding region:191-368 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q8N3K9 uniprotkb:Q16082 intact:EBI-2323272|uniprotkb:Q9UK88|uniprotkb:Q6P5U3|uniprotkb:Q7Z4I1|uniprotkb:Q86T34|uniprotkb:Q86T49|uniprotkb:Q8N3S4|uniprotkb:Q8N3S7|uniprotkb:Q8NAG8|uniprotkb:A0PJB7|uniprotkb:Q05CT4|uniprotkb:Q2NKX1|uniprotkb:Q2T9G9|uniprotkb:Q69YQ8|uniprotkb:Q69YQ9|uniprotkb:Q6P517|ensembl:ENSP00000394770 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:cmya5_human(display_long)|uniprotkb:CMYA5(gene name)|psi-mi:CMYA5(display_short)|uniprotkb:C5orf10(gene name synonym)|uniprotkb:DTNBP2(gene name synonym)|uniprotkb:SPRYD2(gene name synonym)|uniprotkb:TRIM76(gene name synonym)|uniprotkb:Myospryn(gene name synonym)|uniprotkb:Dystrobrevin-binding protein 2(gene name synonym)|uniprotkb:SPRY domain-containing protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 76(gene name synonym)|uniprotkb:Genethonin-3(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487490|imex:IM-25814-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_705838.3|ensembl:ENSG00000164309(gene)|ensembl:ENST00000446378(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016607"(nuclear speck)|go:"GO:0031430"(M band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|mint:Q8N3K9 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:/ZIuVP82yytP9lJaW4+pUyDtQoI9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:qqzNQoYl4PktA1AFoOzmurwTZlA false sufficient binding region:3972-4069 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P47755 uniprotkb:Q16082 intact:EBI-762451|uniprotkb:B4DG50|ensembl:ENSP00000354947 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487482|imex:IM-25814-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006127.1|ensembl:ENSG00000198898(gene)|ensembl:ENST00000361183(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|go:"GO:0016020"(membrane) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:oJ8uzFkjUDjB5gRrvDzoJDnve9Y false sufficient binding region:117-286 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P63261 uniprotkb:Q16082 intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487474|imex:IM-25814-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:t+/arUE+I8P0ukv571yIUqVOSlk false sufficient binding region:195-375 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P68032 uniprotkb:Q16082 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487466|imex:IM-25814-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:bbcWpNXA/eExY0ozOnodBjuy5kY false sufficient binding region:84-377 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P60709 uniprotkb:Q16082 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487458|imex:IM-25814-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:LS5iqazLrR69+gRP8mBjLOulgDo false sufficient binding region:267-375 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q6FGX2 uniprotkb:Q16082 intact:EBI-10249686 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:q6fgx2_human(display_long)|uniprotkb:TNNI3(gene name)|psi-mi:TNNI3(display_short)|uniprotkb:Troponin I, cardiac muscle(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487587|imex:IM-25814-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001978(Troponin)|interpro:IPR021666|refseq:NP_000354.4|go:"GO:0001570"(vasculogenesis)|go:"GO:0001980"(regulation of systemic arterial blood pressure by ischemic conditions)|go:"GO:0003779"(actin binding)|go:"GO:0005861"(troponin complex)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0046872"(metal ion binding)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR038077 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:kLAHLvln+lIzJRQ8Dit1sSKw/6Y9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:yi927IwvhcnQNQakug/8RbNHZDU false sufficient binding region:1..1-210 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P56556 uniprotkb:Q16082 intact:EBI-714658|uniprotkb:O43675|uniprotkb:Q6IC39|uniprotkb:B2RE54|uniprotkb:Q6FGW0|uniprotkb:Q6IBT8|ensembl:ENSP00000418842|ensembl:ENSP00000475402|ensembl:ENSP00000486781|ensembl:ENSP00000487431|ensembl:ENSP00000487462 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:ndua6_human(display_long)|uniprotkb:LYRM6(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B14 subunit(gene name synonym)|uniprotkb:Complex I-B14(gene name synonym)|uniprotkb:LYR motif-containing protein 6(gene name synonym)|uniprotkb:NDUFA6(gene name)|psi-mi:NDUFA6(display_short)|uniprotkb:NADHB14(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487717|imex:IM-25814-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002481.2|ensembl:ENSG00000184983(gene)|ensembl:ENSG00000272765(gene)|ensembl:ENSG00000273397(gene)|ensembl:ENSG00000277365(gene)|ensembl:ENSG00000281013(gene)|ensembl:ENST00000498737(transcript)|ensembl:ENST00000605916(transcript)|ensembl:ENST00000628740(transcript)|ensembl:ENST00000630201(transcript)|ensembl:ENST00000630971(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR016488("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6")|mint:P56556|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2018/07/05 rogid:rI1B6Ym+ps0tKfJIClYRtej8KcU9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:Coxk0wnyvs5fn01oviLtCJiZqMI false sufficient binding region:40-128 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P00414 uniprotkb:Q16082 intact:EBI-3932264|uniprotkb:Q14Y83|ensembl:ENSP00000354982 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:cox3_human(display_long)|uniprotkb:MT-CO3(gene name)|psi-mi:MT-CO3(display_short)|uniprotkb:COIII(gene name synonym)|uniprotkb:COXIII(gene name synonym)|uniprotkb:MTCO3(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide III(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487709|imex:IM-25814-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198938(gene)|ensembl:ENST00000362079(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015453"(oxidoreduction-driven active transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045277"(respiratory chain complex IV)|interpro:IPR000298(Cytochrome c oxidase, subunit III)|interpro:IPR013833(Cytochrome c oxidase, subunit III, 4-helical bundle)|interpro:IPR024791|interpro:IPR033945|interpro:IPR035973|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:YP_003024032.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:ZsGHu+XXEfFZZecGf4EIhwQejAA9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:puYdYjak/oEV+rTeAyV4OdqCnYs false sufficient binding region:1-260 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P00403 uniprotkb:Q16082 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487701|imex:IM-25814-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:UBUPsV7ZrrPnuKjL6AbvEj9tJpo false sufficient binding region:67-227 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P00395 uniprotkb:Q16082 intact:EBI-2117234|uniprotkb:Q34770|ensembl:ENSP00000354499 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:cox1_human(display_long)|uniprotkb:MT-CO1(gene name)|psi-mi:MT-CO1(display_short)|uniprotkb:COI(gene name synonym)|uniprotkb:COXI(gene name synonym)|uniprotkb:MTCO1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide I(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487693|imex:IM-25814-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024028.1|ensembl:ENSG00000198804(gene)|ensembl:ENST00000361624(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0020037"(heme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|interpro:IPR000883(Cytochrome c oxidase, subunit I)|interpro:IPR023615|interpro:IPR023616|interpro:IPR033944|interpro:IPR036927|mint:P00395|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:hPHsY8UxxIWcLFkR9oIoZH5vtls9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:VzMz6uhCRJeqh6X2tBqp5jXDx6A false sufficient binding region:222-512 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P40925-3 uniprotkb:Q16082 intact:EBI-16357808|ensembl:ENSP00000410073 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:p40925-3(display_long)|uniprotkb:Cytosolic malate dehydrogenase(gene name synonym)|uniprotkb:Diiodophenylpyruvate reductase(gene name synonym)|uniprotkb:MDH1(gene name)|psi-mi:MDH1(display_short)|uniprotkb:MDHA(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487684|imex:IM-25814-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-709625(isoform-parent)|ensembl:ENSG00000014641(gene)|ensembl:ENST00000432309(transcript) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - isoform-comment:No experimental confirmation available.|comment:This participant is originally mapped in the publication to P40925, but it has been re-mapped to P40925-3 because the ranges indicated do not properly fit with the original accession. - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/14 rogid:7M9jRvP7wE6RhA8l/qqqJMzlYmU9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:6TMBfQzxfLKE0vbDVKH/aM/Q3Ds false sufficient binding region:68..68-352..352 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9HCC0 uniprotkb:Q16082 intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487676|imex:IM-25814-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:096J+dq6kCdksDjjtWqDCxvZsUo false sufficient binding region:42-563 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P55084 uniprotkb:Q16082 intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487668|imex:IM-25814-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:WfSsHG8B/UPh1m5yrAmF0lVKqLA false sufficient binding region:205..205-452..452 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P04406 uniprotkb:Q16082 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487660|imex:IM-25814-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:JrJcrEotRL62pyANVT8O+f60Xv4 false sufficient binding region:21-293 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P13804 uniprotkb:Q16082 intact:EBI-1052886|uniprotkb:B4DT43|uniprotkb:Q53XN3|ensembl:ENSP00000452762 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:etfa_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487652|imex:IM-25814-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000117.1|refseq:NP_001121188.1|dip:DIP-6161N|ensembl:ENSG00000140374(gene)|ensembl:ENST00000557943(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:P13804|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:J2PUTTVN+nd8eHe6TXga+37CiPw9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:ln/PNdMN5ILEEmaLDkTMkuMXQXI false sufficient binding region:108-284 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P06733 uniprotkb:Q16082 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487644|imex:IM-25814-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:gHI0++53LdqNBE6IzPFdT6TfGDI false sufficient binding region:1..1-341..341 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q16678 uniprotkb:Q16082 intact:EBI-1055133|uniprotkb:Q93089|uniprotkb:Q9H316|uniprotkb:Q5TZW8|ensembl:ENSP00000478561|ensembl:ENSP00000483678 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:cp1b1_human(display_long)|uniprotkb:CYPIB1(gene name synonym)|uniprotkb:CYP1B1(gene name)|psi-mi:CYP1B1(display_short)|uniprotkb:Hydroperoxy icosatetraenoate dehydratase(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487636|imex:IM-25814-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000095.2|ensembl:ENSG00000138061(gene)|ensembl:ENST00000610745(transcript)|ensembl:ENST00000614273(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009404"(toxin metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019373"(epoxygenase P450 pathway)|go:"GO:0020037"(heme binding)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046466"(membrane lipid catabolic process)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0061304"(retinal blood vessel morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070330"(aromatase activity)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0097267"(omega-hydroxylase P450 pathway)|go:"GO:0101020"(estrogen 16-alpha-hydroxylase activity)|go:"GO:0106256"(hydroperoxy icosatetraenoate dehydratase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR032971|interpro:IPR036396|rcsb pdb:3PM0|rcsb pdb:6IQ5|reactome:R-HSA-211976|reactome:R-HSA-2142670|reactome:R-HSA-2142816|reactome:R-HSA-5579000|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:2VJK4lLtHFWOsLQPBDXweKplk+09606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:kpr4hjDS2lGF+eqEGxavsVaobc4 false sufficient binding region:436-543 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P25705 uniprotkb:Q16082 intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487628|imex:IM-25814-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:2hc6rVYaOvEFgSFAXEg+zbDxlQE false sufficient binding region:137-503 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P04075-2 uniprotkb:Q16082 intact:EBI-10194102|ensembl:ENSP00000496166 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:p04075-2(display_long)|uniprotkb:ALDA(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487619|imex:IM-25814-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-709613(isoform-parent)|uniprotkb:P04075-2(isoform-parent)|ensembl:ENSG00000149925(gene)|ensembl:ENST00000642816(transcript) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - comment:This participant is originally mapped in the publication to P04075, but it has been re-mapped to P04075-2 because the ranges indicated do not properly fit with the original accession. - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/14 rogid:pRXhgO2ewyFnCd0Ey+XAWf2cweU9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:NmjbrKVpNa55lukO8PF0tyo1qXI false sufficient binding region:159-418 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P05091 uniprotkb:Q16082 intact:EBI-711703|uniprotkb:Q03639|uniprotkb:Q6IB13|uniprotkb:Q6IV71|uniprotkb:B4DW54|uniprotkb:E7EUE5|ensembl:ENSP00000261733 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:aldh2_human(display_long)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)|uniprotkb:ALDH2(gene name)|psi-mi:ALDH2(display_short)|uniprotkb:ALDM(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487611|imex:IM-25814-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000681.2|refseq:NP_001191818.1|dip:DIP-40262N|ensembl:ENSG00000111275(gene)|ensembl:ENST00000261733(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P05091|rcsb pdb:1CW3|rcsb pdb:1NZW|rcsb pdb:1NZX|rcsb pdb:1NZZ|rcsb pdb:1O00|rcsb pdb:1O01|rcsb pdb:1O02|rcsb pdb:1O04|rcsb pdb:1O05|rcsb pdb:1ZUM|rcsb pdb:2ONM|rcsb pdb:2ONN|rcsb pdb:2ONO|rcsb pdb:2ONP|rcsb pdb:2VLE|rcsb pdb:3INJ|rcsb pdb:3INL|rcsb pdb:3N80|rcsb pdb:3N81|rcsb pdb:3N82|rcsb pdb:3N83|rcsb pdb:3SZ9|rcsb pdb:4FQF|rcsb pdb:4FR8|rcsb pdb:4KWF|rcsb pdb:4KWG|rcsb pdb:5L13|reactome:R-HSA-380612|reactome:R-HSA-71384 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:XvszkFUJP4cXHCYokY16c+LeDEI9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:oXFNAd7BtWX51V9mL7PdpFpKs7E false sufficient binding region:266..266-470..470 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P42765 uniprotkb:Q16082 intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487603|imex:IM-25814-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006102.2|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|interpro:IPR020613|ensembl:ENSG00000167315(gene)|ensembl:ENST00000285093(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:3BQBx+ZyNEkMUuWBqFaRP5tv2nk false sufficient binding region:208-397 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q14240 uniprotkb:Q16082 intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487851|imex:IM-25814-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001958.2|ensembl:ENSG00000156976(gene)|ensembl:ENST00000323963(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:UMMhcP2eYX88cp7EnBkQdkmpEmk false sufficient binding region:360-407 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P13639 uniprotkb:Q16082 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487842|imex:IM-25814-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - comment:This participant is originally mapped in the publication to TrEMBL entry Q6PK56, but it has been re-mapped to P13639 because the ranges indicated do not properly fit with the TrEMBL entry. - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/14 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:n/AihfXW5dzxrVRq4q7OyevyBHM false sufficient binding region:685-858 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P68104 uniprotkb:Q16082 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487834|imex:IM-25814-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:Kb+LvWOob9bzcyXb29WPxCmALac false sufficient binding region:213..213-462..462 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9NWD9 uniprotkb:Q16082 intact:EBI-15105944|ensembl:ENSP00000361776|ensembl:ENSP00000361780 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:bex4_human(display_long)|uniprotkb:BEX4(gene name)|psi-mi:BEX4(display_short)|uniprotkb:BEXL1(gene name synonym)|uniprotkb:NADE3(gene name synonym)|uniprotkb:BEX1-like protein 1(gene name synonym)|uniprotkb:Brain-expressed X-linked protein 4(gene name synonym)|uniprotkb:Nerve growth factor receptor-associated protein 3(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487826|imex:IM-25814-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102409(gene)|ensembl:ENST00000372691(transcript)|ensembl:ENST00000372695(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|interpro:IPR007623(Brain expressed X-linked like protein)|interpro:IPR021156|mint:Q9NWD9|refseq:NP_001073894.1|refseq:NP_001121160.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:BukcZnGYeflhHescSLvqrvZMPHo9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:StwkCQVsum8fIs+979ezpxx+F3E false sufficient binding region:1..1-120 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9H4Z2 uniprotkb:Q16082 intact:EBI-2795590|uniprotkb:B4DLG7|uniprotkb:Q548D0|uniprotkb:Q9H684|ensembl:ENSP00000325326 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:zn335_human(display_long)|uniprotkb:ZNF335(gene name)|psi-mi:ZNF335(display_short)|uniprotkb:NRC-interacting factor 1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487817|imex:IM-25814-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071378.1|ensembl:ENSG00000198026(gene)|ensembl:ENST00000322927(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050671"(positive regulation of lymphocyte proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-5617472 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - comment:This participant is originally mapped in the publication to Q8IW09, but it has been re-mapped to Q9H4Z2 because the ranges indicated do not properly fit with the original accession. - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/14 rogid:9f3nj4Z9/YtwjpEejHkO4S791Qw9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:CLBDdVuXEOXzQZ4a+/WWr++Ez88 false sufficient binding region:610..610-1342..1342 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P07602-2 uniprotkb:Q16082 intact:EBI-16357906 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:p07602-2(display_long)|uniprotkb:Proactivator polypeptide(gene name synonym)|uniprotkb:PSAP(gene name)|psi-mi:PSAP(display_short)|uniprotkb:GLBA(gene name synonym)|uniprotkb:SAP1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487808|imex:IM-25814-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-716699(isoform-parent) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - comment:This participant is originally mapped in the publication to Q5BJH1, but it has been re-mapped to P07602-2 because the ranges indicated do not properly fit with the original accession. - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/14 rogid:GfW3wpRJk1h1B/ub4wvtrZRyuU09606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:skK5j61GYTYwuMQOgfQK/p+oWcY false sufficient binding region:425-526 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9NVD7 uniprotkb:Q16082 intact:EBI-747655|uniprotkb:Q96C85|uniprotkb:Q9HA48|ensembl:ENSP00000334008 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:parva_human(display_long)|uniprotkb:Calponin-like integrin-linked kinase-binding protein(gene name synonym)|uniprotkb:CH-ILKBP(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 2(gene name synonym)|uniprotkb:Actopaxin(gene name synonym)|uniprotkb:PARVA(gene name)|psi-mi:PARVA(display_short)|uniprotkb:MXRA2(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487799|imex:IM-25814-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060692.2|ensembl:ENSG00000197702(gene)|ensembl:ENST00000334956(transcript)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0071670"(smooth muscle cell chemotaxis)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9NVD7|rcsb pdb:2K2R|rcsb pdb:2VZC|rcsb pdb:2VZD|rcsb pdb:2VZG|rcsb pdb:2VZI|rcsb pdb:3KMU|rcsb pdb:3KMW|rcsb pdb:3REP|reactome:R-HSA-446343|reactome:R-HSA-446353|reactome:R-HSA-446388|go:"GO:0005829"(cytosol)|rcsb pdb:6MIB interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:KjiRqYX7cAl33+lH1FnFGfkaZsM9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:TGhq36rMXdbbkt73+1RbncbYhwg false sufficient binding region:141-372 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9NPC6 uniprotkb:Q16082 intact:EBI-746712|uniprotkb:O43415|uniprotkb:Q9HB92|ensembl:ENSP00000306997 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:myoz2_human(display_long)|uniprotkb:Calsarcin-1(gene name synonym)|uniprotkb:FATZ-related protein 2(gene name synonym)|uniprotkb:MYOZ2(gene name)|psi-mi:MYOZ2(display_short)|uniprotkb:C4orf5(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487791|imex:IM-25814-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057683.1|ensembl:ENSG00000172399(gene)|ensembl:ENST00000307128(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003779"(actin binding)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031433"(telethonin binding)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051373"(FATZ binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR008438(Calcineurin-binding) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Y2B5tDM2oGscI8xiTwB69hFEhL89606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:+4S165J0N0R+GQZV4Rfb1u9Hzqs false sufficient binding region:31..31-264..264 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q14192 uniprotkb:Q16082 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487783|imex:IM-25814-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:JcLDiR1yO4q9mpinbiu6FDDwf4o false sufficient binding region:47-279 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P28562 uniprotkb:Q16082 intact:EBI-975493|ensembl:ENSP00000239223|uniprotkb:Q2V508|uniprotkb:D3DQL9 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:dus1_human(display_long)|uniprotkb:Mitogen-activated protein kinase phosphatase 1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase CL100(gene name synonym)|uniprotkb:Dual specificity protein phosphatase hVH1(gene name synonym)|uniprotkb:DUSP1(gene name)|psi-mi:DUSP1(display_short)|uniprotkb:CL100(gene name synonym)|uniprotkb:MKP1(gene name synonym)|uniprotkb:PTPN10(gene name synonym)|uniprotkb:VH1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487775|imex:IM-25814-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120129(gene)|ensembl:ENST00000239223(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001706"(endoderm formation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0008330"(protein tyrosine/threonine phosphatase activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0017017"(MAP kinase tyrosine/serine/threonine phosphatase activity)|go:"GO:0019838"(growth factor binding)|go:"GO:0032355"(response to estradiol)|interpro:IPR020422|interpro:IPR029021|interpro:IPR036873|go:"GO:0032526"(response to retinoic acid)|mint:P28562|rcsb pdb:6APX|rcsb pdb:6D65|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|rcsb pdb:6D66|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|rcsb pdb:6D67|go:"GO:0042542"(response to hydrogen peroxide)|reactome:R-HSA-112409|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|reactome:R-HSA-5675221|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0051591"(response to cAMP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090027"(negative regulation of monocyte chemotaxis)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR008343(MAP kinase phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|refseq:NP_004408.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:HWv2ngjp+me3PbYUNexMd0viYPw9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:OmiJByK0i7mWrlFNamhPkCjc6Dg false sufficient binding region:158-367 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9NX09 uniprotkb:Q16082 intact:EBI-715104|uniprotkb:Q9H0S3|ensembl:ENSP00000307305|ensembl:ENSP00000506356 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:ddit4_human(display_long)|uniprotkb:RTP801(gene name synonym)|uniprotkb:Protein regulated in development and DNA damage response 1(gene name synonym)|uniprotkb:HIF-1 responsive protein RTP801(gene name synonym)|uniprotkb:DDIT4(gene name)|psi-mi:DDIT4(display_short)|uniprotkb:REDD1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487767|imex:IM-25814-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061931.1|ensembl:ENSG00000168209(gene)|ensembl:ENST00000307365(transcript)|ensembl:ENST00000491934(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR012918(RTP801, C-terminal)|interpro:IPR038281|mint:Q9NX09|rcsb pdb:3LQ9|reactome:R-HSA-5628897|go:"GO:1902532"(negative regulation of intracellular signal transduction) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Tgt6EJ1lV/mHUCBM7W8XDINZusU9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:ZscN22Qgm5CR0052SRHlE9aPLDM false sufficient binding region:167-232 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q8TF27 uniprotkb:Q16082 intact:EBI-15105905|uniprotkb:B9EIP7|uniprotkb:D3DWE4 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:aga11_human(display_long)|uniprotkb:AGAP11(gene name)|psi-mi:AGAP11(display_short)|uniprotkb:KIAA1975(gene name synonym)|uniprotkb:Centaurin-gamma-like protein KIAA1975(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487759|imex:IM-25814-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_597704.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR038508|interpro:IPR036770|interpro:IPR037278 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:OsIFImgR4cPNj3QLxNUe2p4LC3Q9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:AHheaYVbggWfFX1VzAi4HWHxQDQ false sufficient binding region:19..19-550..550 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:D6RFM5 uniprotkb:Q16082 intact:EBI-15105883|ensembl:ENSP00000426514 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:d6rfm5_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487750|imex:IM-25814-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000073578(gene)|ensembl:ENST00000504309(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0022900"(electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|refseq:NP_001317687.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:o0IrqLFiw5VBoNa+S4s7vMtynTQ9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:E4pmGbQwThL+rEmlYrKIcaUOHQo false sufficient binding region:?-? - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P36871 uniprotkb:Q16082 intact:EBI-2861475|uniprotkb:Q5BKZ9|uniprotkb:Q96J40|uniprotkb:Q9NTY4|uniprotkb:Q6NW22|uniprotkb:Q86U74|uniprotkb:Q16105|uniprotkb:B2R5N9|uniprotkb:B4DPV0|uniprotkb:Q16106|ensembl:ENSP00000360125 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:pgm1_human(display_long)|uniprotkb:PGM1(gene name)|psi-mi:PGM1(display_short)|uniprotkb:Glucose phosphomutase 1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487742|imex:IM-25814-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001166289.1|refseq:NP_001166290.1|refseq:NP_002624.2|dip:DIP-60903N|reactome:R-HSA-5609974|reactome:R-HSA-6798695|reactome:R-HSA-3322077|ensembl:ENSG00000079739(gene)|ensembl:ENST00000371084(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900|rcsb pdb:5EPC|rcsb pdb:5F9C|rcsb pdb:5HSH|rcsb pdb:5JN5|rcsb pdb:5TR2|rcsb pdb:5VBI|rcsb pdb:5VEC|rcsb pdb:5VG7|rcsb pdb:5VIN|rcsb pdb:6SNO|rcsb pdb:6SNP|rcsb pdb:6SNQ|rcsb pdb:6UIQ|rcsb pdb:6UO6 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:K9cGu3lfysJ4hVP0S0jewZsZjSE9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:twHOdv5rvHgwmFigWbw+pvKUhaI false sufficient binding region:250..250-365..365 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:A2VCT2 uniprotkb:Q16082 intact:EBI-15105872 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:a2vct2_human(display_long)|uniprotkb:OGDH(gene name)|psi-mi:OGDH(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487733|imex:IM-25814-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030976"(thiamine pyrophosphate binding)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR005475(Transketolase, central region) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:cs7joFFsTRxep7nM6Qc9mhx60go9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:tcHyg8dcDahq6/4H56K18p0VS24 false sufficient binding region:?-? - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9P0J0 uniprotkb:Q16082 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487725|imex:IM-25814-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:1++Wu4iErA7iHDwIQuNXTbXA6p0 false sufficient binding region:1-144 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P55769 uniprotkb:Q16082 intact:EBI-712228|ensembl:ENSP00000215956|ensembl:ENSP00000383949|ensembl:ENSP00000497142 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:nh2l1_human(display_long)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:High mobility group-like nuclear protein 2 homolog 1(gene name synonym)|uniprotkb:NHP2L1(gene name synonym)|uniprotkb:OTK27(gene name synonym)|uniprotkb:SNU13 homolog(gene name synonym)|uniprotkb:U4/U6.U5 small nuclear ribonucleoprotein SNU13(gene name synonym)|uniprotkb:U4/U6.U5 tri-snRNP 15.5 kDa protein(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487975|imex:IM-25814-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100138(gene)|ensembl:ENST00000215956(transcript)|ensembl:ENST00000401959(transcript)|ensembl:ENST00000648674(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0007338"(single fertilization)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051117"(ATPase binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P55769|rcsb pdb:1E7K|rcsb pdb:2JNB|rcsb pdb:2OZB|rcsb pdb:3JCR|rcsb pdb:3SIU|rcsb pdb:3SIV|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_001003796.1|refseq:NP_004999.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:ZMkqsDfMCrTlT/kJxillOA8839E9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:ASC8IsOWsh6uS7o9IRmVWT2xigE false sufficient binding region:41..41-123..123 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P62913 uniprotkb:Q16082 intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487983|imex:IM-25814-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:KL0KuQStLxioMkX/YjyJWjDjgjw false sufficient binding region:83-177 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:J3KQN4 uniprotkb:Q16082 intact:EBI-15105974|ensembl:ENSP00000404375|ensembl:ENSP00000483017 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:j3kqn4_human(display_long)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487991|imex:IM-25814-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000241343(gene)|ensembl:ENST00000427805(transcript)|ensembl:ENST00000614077(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|rcsb pdb:6W6L|rcsb pdb:6Z6L|refseq:NP_066357.2 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:gmo74tTtuIcJfiwJqC5FRZ8xCYg9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:nLtKzmmn30PUQx2JSlL5f/voZIA false sufficient binding region:81-142 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q969Q0 uniprotkb:Q16082 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487999|imex:IM-25814-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:XcANQNyKw1XaS3iX3dTcDJc9j+g false sufficient binding region:45-106 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P41250 uniprotkb:Q16082 intact:EBI-724143|uniprotkb:B3KQA2|uniprotkb:B4DIA0|ensembl:ENSP00000373918|uniprotkb:Q969Y1|intact:EBI-25629666|uniprotkb:A0A090N8G0 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:gars_human(display_long)|uniprotkb:GARS1(gene name)|psi-mi:GARS1(display_short)|uniprotkb:Diadenosine tetraphosphate synthetase(gene name synonym)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase 1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487959|imex:IM-25814-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002038.2|rcsb pdb:4KQE|rcsb pdb:4KR2|rcsb pdb:2ZT6|rcsb pdb:4KR3|rcsb pdb:4QEI|rcsb pdb:5E6M|reactome:R-HSA-379716|rcsb pdb:2ZT7|reactome:R-HSA-379726|rcsb pdb:2ZT8|rcsb pdb:2ZXF|ensembl:ENSG00000106105(gene)|ensembl:ENST00000389266(transcript)|go:"GO:0004081"("bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity")|go:"GO:0004820"(glycine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006426"(glycyl-tRNA aminoacylation)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016740"(transferase activity)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070150"(mitochondrial glycyl-tRNA aminoacylation)|interpro:IPR000738(WHEP-TRS)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002315(Glycyl-tRNA synthetase, alpha2 dimer)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR027031|interpro:IPR033731|interpro:IPR036621|mint:P41250|rcsb pdb:2PME|rcsb pdb:2PMF|rcsb pdb:2Q5H|rcsb pdb:2Q5I|rcsb pdb:2ZT5|refseq:NP_001303701.1|dip:DIP-50471N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:bBlAPOMGXKsEvu0DxGKJJLjDI1s9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:5atlIIB6h04gK9NQJh7URVsAtCk false sufficient binding region:254..254-739..739 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:O43776 uniprotkb:Q16082 intact:EBI-373505|uniprotkb:Q53GU6|uniprotkb:B4DG16|ensembl:ENSP00000256854 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:sync_human(display_long)|uniprotkb:NARS1(gene name)|psi-mi:NARS1(display_short)|uniprotkb:Asparaginyl-tRNA synthetase(gene name synonym)|uniprotkb:Asparaginyl-tRNA synthetase 1(gene name synonym)|uniprotkb:NARS(gene name synonym)|uniprotkb:NRS(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15487967|imex:IM-25814-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004530.1|ensembl:ENSG00000134440(gene)|ensembl:ENST00000256854(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004816"(asparagine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006421"(asparaginyl-tRNA aminoacylation)|go:"GO:0016477"(cell migration)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031728"(CCR3 chemokine receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004522(Asparaginyl-tRNA synthetase, class IIb)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:4ZYA|rcsb pdb:5XIX|reactome:R-HSA-379716 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:yCKLNQEoXyLaJC0PpYOoefQawss9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:sNkqhSUiZfB6vqo+TumkfBxL8S8 false sufficient binding region:379-548 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q6LEU2 uniprotkb:Q16082 intact:EBI-15106055 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:q6leu2_human(display_long)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488170|imex:IM-25814-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042383"(sarcolemma)|interpro:IPR038702|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:JOJls3oO3EI6T5XmTgd9et1nq7k9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:ry7G12BzeIJki4nX9wxus6Gnn0M false sufficient binding region:101-303 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q99959 uniprotkb:Q16082 intact:EBI-702235|intact:EBI-2692870|uniprotkb:D3DUW9|uniprotkb:Q99960|uniprotkb:Q4VC01|uniprotkb:B8QFA1|uniprotkb:B8QGS6|uniprotkb:B8QGS7|uniprotkb:A0AV37|ensembl:ENSP00000070846 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:pkp2_human(display_long)|uniprotkb:PKP2(gene name)|psi-mi:PKP2(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488162|imex:IM-25814-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004563.2|refseq:NP_001005242.2|ensembl:ENSG00000057294(gene)|ensembl:ENST00000070846(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002159"(desmosome assembly)|go:"GO:0002934"(desmosome organization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007507"(heart development)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:Q99959|rcsb pdb:3TT9|reactome:R-HSA-6805567|reactome:R-HSA-6809371 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:kwGWMlk4SDz0xARlBMD1dY9fehQ9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:WNLU+yrREDZQ7b6jUkqUk06iNXE false sufficient binding region:619-837 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P09382 uniprotkb:Q16082 intact:EBI-1048875|uniprotkb:B2R5E8|uniprotkb:Q9UDK5|ensembl:ENSP00000215909 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:leg1_human(display_long)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:HPL(gene name synonym)|uniprotkb:HBL(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM12(gene name synonym)|uniprotkb:LGALS1(gene name)|psi-mi:LGALS1(display_short)|uniprotkb:Lactose-binding lectin 1(gene name synonym)|uniprotkb:14 kDa laminin-binding protein(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488154|imex:IM-25814-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002296.1|ensembl:ENST00000215909(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|ensembl:ENSG00000100097(gene)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P09382|rcsb pdb:1GZW|rcsb pdb:1W6M|rcsb pdb:1W6N|rcsb pdb:1W6O|rcsb pdb:1W6P|rcsb pdb:1W6Q|rcsb pdb:2KM2|rcsb pdb:2ZKN|rcsb pdb:3OY8|rcsb pdb:3OYW|rcsb pdb:3T2T|rcsb pdb:3W58|rcsb pdb:3W59|rcsb pdb:4Q1P|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4Q1R|rcsb pdb:4Q26|rcsb pdb:4Q27|rcsb pdb:4Q2F|rcsb pdb:4XBL|rcsb pdb:4Y1U|rcsb pdb:4Y1V|rcsb pdb:4Y1X|rcsb pdb:4Y1Y|rcsb pdb:4Y1Z|rcsb pdb:4Y20|rcsb pdb:4Y22|rcsb pdb:4Y24|rcsb pdb:5MWT|rcsb pdb:5MWX|rcsb pdb:6B94|rcsb pdb:6F83|rcsb pdb:6M5Y|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-46153N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Sov3RfY2NOjdjuvdFlEd/vaNTMY9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:FuY2rdUeWy3LTxqyeg5nQ7VsMSk false sufficient binding region:1..1-135 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q5TEJ8 uniprotkb:Q16082 intact:EBI-2806032|uniprotkb:B4DZT9|uniprotkb:Q9NS90|uniprotkb:Q9BYB6|uniprotkb:Q5TEJ1|uniprotkb:Q68DP4|uniprotkb:A2RTZ3|uniprotkb:Q5TEJ9|uniprotkb:O60560|uniprotkb:Q5TEK1|uniprotkb:B4DZY3|ensembl:ENSP00000363031 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:thms2_human(display_long)|uniprotkb:C1orf38(gene name synonym)|uniprotkb:ICB1(gene name synonym)|uniprotkb:Induced by contact to basement membrane 1 protein(gene name synonym)|uniprotkb:Thymocyte-expressed molecule involved in selection protein 2(gene name synonym)|uniprotkb:THEMIS2(gene name)|psi-mi:THEMIS2(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488146|imex:IM-25814-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273042.1|refseq:NP_001273044.1|refseq:NP_001034566.1|refseq:NP_001099026.1|refseq:NP_004839.2|ensembl:ENSG00000130775(gene)|ensembl:ENST00000373921(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050864"(regulation of B cell activation)|interpro:IPR025946|interpro:IPR039671|refseq:XP_006711113.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:d3p6WXby4vsV/5OIxCObzfSkoE89606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:mmNQ1/oh6XZUxOGaN4UypSggUfQ false sufficient binding region:246-447 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P02745 uniprotkb:Q16082 intact:EBI-1220209|uniprotkb:Q5T963|uniprotkb:B2R4X2|ensembl:ENSP00000363773|ensembl:ENSP00000385564 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:c1qa_human(display_long)|uniprotkb:C1QA(gene name)|psi-mi:C1QA(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488138|imex:IM-25814-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057075.1|refseq:NP_001334394.1|refseq:NP_001334395.1|ensembl:ENSG00000173372(gene)|ensembl:ENST00000374642(transcript)|ensembl:ENST00000402322(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005602"(complement component C1 complex)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0010039"(response to iron ion)|go:"GO:0016322"(neuron remodeling)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048143"(astrocyte activation)|go:"GO:0050808"(synapse organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR037572|rcsb pdb:1PK6|rcsb pdb:2JG8|rcsb pdb:2JG9|rcsb pdb:2WNU|rcsb pdb:2WNV|rcsb pdb:5HKJ|rcsb pdb:5HZF|rcsb pdb:6FCZ|rcsb pdb:6Z6V|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:JOnVJ11QPTmKEEGIr3BAlb2j6+s9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:x2hqdsyBCv7nBX9EV8O9ymz7yO0 false sufficient binding region:134-245 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P61769 uniprotkb:Q16082 intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191|ensembl:ENSP00000453350|ensembl:ENSP00000481426|ensembl:ENSP00000488321|ensembl:ENSP00000488548|ensembl:ENSP00000497910 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488130|imex:IM-25814-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5INC|rcsb pdb:5TXS|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5U16|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6D2B|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6PTE|rcsb pdb:6P2F|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VB4|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7C9V|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MKB|rcsb pdb:7NUI|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-977225|reactome:R-HSA-983170|ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000559916(transcript)|ensembl:ENST00000561424(transcript)|ensembl:ENST00000617605(transcript)|ensembl:ENST00000631573(transcript)|ensembl:ENST00000631728(transcript)|ensembl:ENST00000648006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005925"(focal adhesion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1T20|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UR7|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1ZHK|rcsb pdb:1T1W|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:1T1X|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:1T1Y|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:1T1Z|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|refseq:NP_004039.1|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3KPO|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3KXF|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3KYN|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:3T8X|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4L3E|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:4XXC|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|dip:DIP-6055N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:kFkHLDj2cspV/PWpkzXN6Sdx0uk false sufficient binding region:1..1-119 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q6P1N9 uniprotkb:Q16082 intact:EBI-9351004|uniprotkb:B2R5J0|uniprotkb:Q8TD02|uniprotkb:Q9BY40|ensembl:ENSP00000276692 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:tatd1_human(display_long)|uniprotkb:TATDN1(gene name)|psi-mi:TATDN1(display_short)|uniprotkb:Hepatocarcinoma high expression protein(gene name synonym)|uniprotkb:CDA11(orf name) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488121|imex:IM-25814-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304819.1|refseq:NP_001304820.1|refseq:XP_016869387.1|refseq:NP_001139632.1|refseq:NP_114415.1|ensembl:ENSG00000147687(gene)|ensembl:ENST00000276692(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0046872"(metal ion binding)|interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|rcsb pdb:2XIO interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Z2tUbe0SUXNflTLjN0w9ls+Vdbg9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:ZVZTuAqChaqlEpnCVdu/zd8rOFo false sufficient binding region:1..1-297..297 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q16774 uniprotkb:Q16082 intact:EBI-2340074|uniprotkb:B1ANH1|ensembl:ENSP00000317659|ensembl:ENSP00000355677|ensembl:ENSP00000355679|ensembl:ENSP00000355687|ensembl:ENSP00000355691 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:kgua_human(display_long)|uniprotkb:GUK1(gene name)|psi-mi:GUK1(display_short)|uniprotkb:GMK(gene name synonym)|uniprotkb:GMP kinase(gene name synonym)|uniprotkb:GMPK(gene name synonym)|uniprotkb:Guanylate kinase 1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488112|imex:IM-25814-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000849.1|refseq:NP_001152863.1|refseq:NP_001229768.1|refseq:NP_001152862.1|refseq:NP_001229769.1|ensembl:ENSG00000143774(gene)|ensembl:ENST00000312726(transcript)|ensembl:ENST00000366716(transcript)|ensembl:ENST00000366718(transcript)|ensembl:ENST00000366726(transcript)|ensembl:ENST00000366730(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0006185"(dGDP biosynthetic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0034436"(glycoprotein transport)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046054"(dGMP metabolic process)|go:"GO:0046060"(dATP metabolic process)|go:"GO:0046711"(GDP biosynthetic process)|go:"GO:0046939"(nucleotide phosphorylation)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR017665(Guanylate kinase, sub-group)|interpro:IPR020590|interpro:IPR027417|rcsb pdb:6NUI|reactome:R-HSA-2161541|reactome:R-HSA-499943 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - comment:This participant is originally mapped in the publication to TrEMBL entry Q96IN2, but it has been re-mapped to Q16774 because the ranges indicated do not properly fit with the TrEMBL entry. - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/14 rogid:XJ4OokT2+8LY9P1bUKmFwmRXt249606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:oxTCUAXRxg4EbVAzn2yN4Mz8YdQ false sufficient binding region:11-197 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P06732 uniprotkb:Q16082 intact:EBI-4287089|uniprotkb:Q96QL9|ensembl:ENSP00000221476 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:kcrm_human(display_long)|uniprotkb:CKM(gene name)|psi-mi:CKM(display_short)|uniprotkb:CKMM(gene name synonym)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488104|imex:IM-25814-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001815.2|ensembl:ENSG00000104879(gene)|ensembl:ENST00000221476(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P06732|rcsb pdb:1I0E|reactome:R-HSA-71288|go:"GO:0005524"(ATP binding)|refseq:XP_016881729.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:zuj1pG+YNft6wFPHLPoS+CTamkE9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:+7js+5FpLoR7RYkr0souWt8H26Y false sufficient binding region:133..133-381..381 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P07339 uniprotkb:Q16082 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488095|imex:IM-25814-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:bdxYMCh3KA+ZcxsbMh6WWm7Ihow false sufficient binding region:228..229-412 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P07858 uniprotkb:Q16082 intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000503300|ensembl:ENSP00000503435|ensembl:ENSP00000503487|ensembl:ENSP00000503513|ensembl:ENSP00000503578|ensembl:ENSP00000503608|ensembl:ENSP00000503652|ensembl:ENSP00000503674|ensembl:ENSP00000503858|ensembl:ENSP00000503909|ensembl:ENSP00000504161|ensembl:ENSP00000504226|ensembl:ENSP00000504336|ensembl:ENSP00000504480|ensembl:ENSP00000504638|ensembl:ENSP00000504659|ensembl:ENSP00000504797|ensembl:ENSP00000503280|ensembl:ENSP00000342070|ensembl:ENSP00000345672|ensembl:ENSP00000431143|ensembl:ENSP00000431518|ensembl:ENSP00000432077|ensembl:ENSP00000432244|ensembl:ENSP00000432408|ensembl:ENSP00000433215|ensembl:ENSP00000433379|ensembl:ENSP00000433929|ensembl:ENSP00000434217|ensembl:ENSP00000434725|ensembl:ENSP00000435074|ensembl:ENSP00000435105|ensembl:ENSP00000435260|ensembl:ENSP00000435886|ensembl:ENSP00000473301|ensembl:ENSP00000502963|ensembl:ENSP00000503006|ensembl:ENSP00000503052|ensembl:ENSP00000503078|ensembl:ENSP00000503174 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488087|imex:IM-25814-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|ensembl:ENST00000345125(transcript)|ensembl:ENST00000353047(transcript)|ensembl:ENST00000524654(transcript)|ensembl:ENST00000526481(transcript)|ensembl:ENST00000526645(transcript)|ensembl:ENST00000527215(transcript)|ensembl:ENST00000534382(transcript)|ensembl:ENST00000527243(transcript)|ensembl:ENST00000534510(transcript)|ensembl:ENST00000676691(transcript)|ensembl:ENST00000676755(transcript)|ensembl:ENST00000676825(transcript)|ensembl:ENST00000676843(transcript)|ensembl:ENST00000676952(transcript)|ensembl:ENST00000677082(transcript)|ensembl:ENST00000677366(transcript)|ensembl:ENST00000677415(transcript)|ensembl:ENST00000528965(transcript)|ensembl:ENST00000530296(transcript)|ensembl:ENST00000530640(transcript)|ensembl:ENST00000677418(transcript)|ensembl:ENST00000677544(transcript)|ensembl:ENST00000677650(transcript)|ensembl:ENST00000677671(transcript)|ensembl:ENST00000677819(transcript)|ensembl:ENST00000677873(transcript)|ensembl:ENST00000678092(transcript)|ensembl:ENST00000678145(transcript)|ensembl:ENST00000678242(transcript)|ensembl:ENST00000531089(transcript)|ensembl:ENST00000678357(transcript)|ensembl:ENST00000531502(transcript)|ensembl:ENST00000678615(transcript)|ensembl:ENST00000532392(transcript)|ensembl:ENST00000678929(transcript)|ensembl:ENST00000532656(transcript)|ensembl:ENST00000533455(transcript)|ensembl:ENST00000679051(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042981"(regulation of apoptotic process)|ensembl:ENST00000679128(transcript)|go:"GO:0043394"(proteoglycan binding)|ensembl:ENST00000679140(transcript)|go:"GO:0046697"(decidualization)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|ensembl:ENSG00000164733(gene)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1CSB|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:XP_006716307.1|refseq:XP_006716308.1|dip:DIP-42785N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:y9Ul/5QT9A5sWvB5KQxGNZLP6vg false sufficient binding region:238-339 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P01023 uniprotkb:Q16082 intact:EBI-640741|uniprotkb:Q13677|uniprotkb:Q59F47|uniprotkb:Q5QTS0|uniprotkb:Q68DN2|uniprotkb:Q6PIY3|uniprotkb:Q6PN97|ensembl:ENSP00000323929 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:a2mg_human(display_long)|uniprotkb:CPAMD5(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5(gene name synonym)|uniprotkb:A2M(gene name)|psi-mi:A2M(display_short)|uniprotkb:FWP007(orf name) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488079|imex:IM-25814-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000005.2|refseq:NP_001334352.1|refseq:NP_001334353.1|refseq:NP_001334354.1|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|mint:P01023|rcsb pdb:1BV8|rcsb pdb:2P9R|rcsb pdb:4ACQ|rcsb pdb:6TAV|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-1474228|reactome:R-HSA-8963896|ensembl:ENSG00000175899(gene)|ensembl:ENST00000318602(transcript)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0002020"(protease binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0019838"(growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|dip:DIP-1118N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:FClLRDrtOWUx0eBBCUfAocx0Q+49606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:1bzKMW/GtrPLIbqjHKmi8osJ4KY false sufficient binding region:1184..1184-1474..1474 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P11166 uniprotkb:Q16082 intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488071|imex:IM-25814-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:PuLbdvOyUmY9gCixKiD/j+zHW28 false sufficient binding region:369-492 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q99470 uniprotkb:Q16082 intact:EBI-2515769|ensembl:ENSP00000247020|uniprotkb:Q9BQ79 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:sdf2_human(display_long)|uniprotkb:SDF2(gene name)|psi-mi:SDF2(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488063|imex:IM-25814-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132581(gene)|ensembl:ENST00000247020(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR016093(MIR motif)|interpro:IPR036300|refseq:NP_008854.2 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:j0jeyDbvcmC8s+1awSiR7K/hyxo9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:dR4PHiC4qn467f29UMBPrUxp+BQ false sufficient binding region:1-211 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q8N3J5 uniprotkb:Q16082 intact:EBI-3923368|uniprotkb:Q49AB5|uniprotkb:Q8ND70|uniprotkb:Q56AN8|uniprotkb:B2RAZ1|uniprotkb:Q96NT4|uniprotkb:Q4W5E6|uniprotkb:Q05CT5|uniprotkb:Q8IXG7|uniprotkb:Q8IUZ7|ensembl:ENSP00000477341 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:ppm1k_human(display_long)|uniprotkb:PPM1K(gene name)|psi-mi:PPM1K(display_short)|uniprotkb:PP2CM(gene name synonym)|uniprotkb:PP2C domain-containing protein phosphatase 1K(gene name synonym)|uniprotkb:PP2C-like mitochondrial protein(gene name synonym)|uniprotkb:PP2C-type mitochondrial phosphoprotein phosphatase(gene name synonym)|uniprotkb:Protein phosphatase 2C isoform kappa(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488055|imex:IM-25814-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2IQ1|rcsb pdb:4DA1|rcsb pdb:6AK7|reactome:R-HSA-70895|mint:Q8N3J5|refseq:NP_689755.3|ensembl:ENSG00000163644(gene)|ensembl:ENST00000608933(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR036457|refseq:XP_006714174.1|refseq:XP_016863292.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:wS28kmLswahhmPndEC0URywVGis9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:uArrBFL8VHtDqlEQM7hb0TZ9DgU false sufficient binding region:260-372 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P02144 uniprotkb:Q16082 intact:EBI-15106010|ensembl:ENSP00000352835|ensembl:ENSP00000380489|ensembl:ENSP00000380491|ensembl:ENSP00000384239|uniprotkb:Q52H51|uniprotkb:Q5THY7 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:myg_human(display_long)|uniprotkb:MB(gene name)|psi-mi:MB(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488047|imex:IM-25814-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0009725"(response to hormone)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031444"(slow-twitch skeletal muscle fiber contraction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000971(Globin, subset)|interpro:IPR002335(Myoglobin)|interpro:IPR009050(Globin-like)|rcsb pdb:3RGK|reactome:R-HSA-8981607|ensembl:ENSG00000198125(gene)|ensembl:ENST00000359787(transcript)|ensembl:ENST00000397326(transcript)|ensembl:ENST00000397328(transcript)|ensembl:ENST00000406324(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005344"(oxygen carrier activity)|refseq:NP_005359.1|refseq:NP_976311.1|refseq:NP_976312.1|refseq:XP_005261662.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Jo60sJpIhxWoLOxlkbCZOhcBwG09606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:T/G7je0mhwJPHQfaavU6inzbdQ4 false sufficient binding region:9-154 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q53Y06 uniprotkb:Q16082 intact:EBI-1047436 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:q53y06_human(display_long)|uniprotkb:ATP6V1E1(gene name)|psi-mi:ATP6V1E1(display_short)|uniprotkb:hCG_21530(orf name) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488039|imex:IM-25814-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|refseq:NP_001687.1|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR038495 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:tTf7Cl6DOsN3USZrmZijWhmhEhg9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:KByhF0bC7pOBcXd3F4KEY1ZYQYw false sufficient binding region:165..165-196..196 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:O14678 uniprotkb:Q16082 intact:EBI-714396|ensembl:ENSP00000349396|uniprotkb:Q6IAQ0|uniprotkb:Q96E75|uniprotkb:A8K5L7 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:abcd4_human(display_long)|uniprotkb:Peroxisomal membrane protein 69(gene name synonym)|uniprotkb:Peroxisomal membrane protein 1-like(gene name synonym)|uniprotkb:PMP70-related protein(gene name synonym)|uniprotkb:ABCD4(gene name)|psi-mi:ABCD4(display_short)|uniprotkb:PXMP1L(gene name synonym)|uniprotkb:ATP-binding cassette sub-family D member 4(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488031|imex:IM-25814-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119688(gene)|ensembl:ENST00000356924(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0015420"(ABC-type vitamin B12 transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0055085"(transmembrane transport)|go:"GO:0140359"(ABC-type transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|rcsb pdb:6JBJ|reactome:R-HSA-196741|reactome:R-HSA-5683329|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|refseq:NP_005041.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:ojfuYsHtwnxPMTGv3j6UAHICYOI9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:U4wrOw0lcA49GEwi3dEhgiRkaZA false sufficient binding region:204-606 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q16082 uniprotkb:O60706 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-9008881|ensembl:ENSP00000261201|uniprotkb:O60707 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:abcc9_human(display_long)|uniprotkb:ABCC9(gene name)|psi-mi:ABCC9(display_short)|uniprotkb:SUR2(gene name synonym)|uniprotkb:Sulfonylurea receptor 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488023|imex:IM-25814-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 refseq:XP_011518847.1|go:"GO:0061337"(cardiac conduction)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000388(Sulphonylurea receptor, N-terminus)|interpro:IPR001475(Sulphonylurea receptor, type 2, N-terminus)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|reactome:R-HSA-1296025|reactome:R-HSA-382556|reactome:R-HSA-5578775|reactome:R-HSA-5678420|ensembl:ENSG00000069431(gene)|ensembl:ENST00000261201(transcript)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008281"(sulfonylurea receptor activity)|go:"GO:0008282"(inward rectifying potassium channel)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030017"(sarcomere)|go:"GO:0031004"(potassium ion-transporting ATPase complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0055085"(transmembrane transport)|refseq:NP_005682.2|refseq:NP_064693.2|refseq:XP_005253341.1|refseq:XP_005253343.1|refseq:XP_005253344.1|refseq:XP_005253345.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:WDuOtY4Ll5cAIxhvQUkvQzlatDs9606 rigid:D8zpNhL9kP5C6M1RENj9fpaH6xA false - sufficient binding region:1263..1263-1549..1549 - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9BTF0 uniprotkb:Q16082 intact:EBI-15105991|ensembl:ENSP00000423933|uniprotkb:A8K7I7|uniprotkb:Q53TT8|uniprotkb:Q53TV0 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:thum2_human(display_long)|uniprotkb:THUMPD2(gene name)|psi-mi:THUMPD2(display_short)|uniprotkb:C2orf8(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488015|imex:IM-25814-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138050(gene)|ensembl:ENST00000505747(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016423"("tRNA (guanine) methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|interpro:IPR000241(Putative RNA methylase)|interpro:IPR004114(THUMP)|interpro:IPR029063|refseq:NP_079540.2 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:/FlbZxWXR0deWNVt6bK2QnRk25o9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:Bk1DsePWUt4AWEA8Pmi7cAI2Gbw false sufficient binding region:11..11-503..503 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P62280 uniprotkb:Q16082 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488007|imex:IM-25814-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:05c5y1j0pqredbxy0Mz0dH2nfyk false sufficient binding region:90-158 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q13510 uniprotkb:Q16082 intact:EBI-714581|uniprotkb:Q6W898|uniprotkb:E9PDS0|uniprotkb:Q96AS2|ensembl:ENSP00000490272|ensembl:ENSP00000490506 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:asah1_human(display_long)|uniprotkb:Acylsphingosine deacylase(gene name synonym)|uniprotkb:N-acylsphingosine amidohydrolase(gene name synonym)|uniprotkb:Putative 32 kDa heart protein(gene name synonym)|uniprotkb:HSD33(orf name)|uniprotkb:ASAH1(gene name)|psi-mi:ASAH1(display_short)|uniprotkb:ASAH(gene name synonym)|uniprotkb:HSD-33(orf name)|uniprotkb:N-acylethanolamine hydrolase ASAH1(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488178|imex:IM-25814-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120977.1|refseq:NP_004306.3|refseq:NP_808592.2|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046514"(ceramide catabolic process)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0062098"(regulation of programmed necrotic cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0102121"(ceramidase activity)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR016699(Acid ceramidase-like)|interpro:IPR029130|interpro:IPR029132|mint:Q13510|rcsb pdb:5U7Z|rcsb pdb:6MHM|reactome:R-HSA-1660662|go:"GO:0017064"(fatty acid amide hydrolase activity)|ensembl:ENSG00000104763(gene)|ensembl:ENST00000635998(transcript)|ensembl:ENST00000637790(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017040"(N-acylsphingosine amidohydrolase activity)|reactome:R-HSA-6798695 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:nVtUQ1YDfManbzaGXOGLSO8qzks9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:zfKVYofGR5osp7kRyN141WoQGKQ false sufficient binding region:290-389 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9H3M7 uniprotkb:Q16082 intact:EBI-1369170|uniprotkb:B4E3D3|uniprotkb:Q16226|uniprotkb:Q6PML0|uniprotkb:Q9BXG9|ensembl:ENSP00000462521 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:txnip_human(display_long)|uniprotkb:TXNIP(gene name)|psi-mi:TXNIP(display_short)|uniprotkb:VDUP1(gene name synonym)|uniprotkb:Vitamin D3 up-regulated protein 1(gene name synonym)|uniprotkb:Thioredoxin-binding protein 2(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488186|imex:IM-25814-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006463.3|refseq:NP_001300901.1|ensembl:ENSG00000265972(gene)|ensembl:ENST00000582401(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051782"(negative regulation of cell division)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|rcsb pdb:4GEI|rcsb pdb:4GEJ|rcsb pdb:4GFX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4ROF|rcsb pdb:4ROJ|rcsb pdb:5CQ2|rcsb pdb:5DF6|rcsb pdb:5DWS|rcsb pdb:5DZD|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9707564|go:"GO:0071228"(cellular response to tumor cell) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:jJMKfl1/92UPMTXBLCdu6NcYbjQ9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:Uc/LsqIOQwZRD9orYCbF2kKZheU false sufficient binding region:175-391 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q16082 uniprotkb:Q16082 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488194|imex:IM-25814-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:H5PIDsXMcenEuxT74I///Cxi89w false sufficient binding region:1..1-175 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:P02511 uniprotkb:Q16082 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488202|imex:IM-25814-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - crc64:AE08BED46B7849CB - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:uTSG+JnXz+brnfQsiBgort2vO2A false sufficient binding region:1..1-175 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:O00399 uniprotkb:Q16082 intact:EBI-2559415|uniprotkb:B2RAC1|ensembl:ENSP00000221114 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488210|imex:IM-25814-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006562.1|ensembl:ENSG00000104671(gene)|ensembl:ENST00000221114(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:Hl+xieXy83FpxteIHEEYtseNR4s false sufficient binding region:82-190 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q9H857 uniprotkb:Q16082 intact:EBI-359244|uniprotkb:O95888|uniprotkb:Q96C80|uniprotkb:Q9H9Z8|uniprotkb:C9JTZ6|uniprotkb:E9PAL9|intact:EBI-11044897|ensembl:ENSP00000302468 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:nt5d2_human(display_long)|uniprotkb:NT5DC2(gene name)|psi-mi:NT5DC2(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488226|imex:IM-25814-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001127703.1|refseq:NP_075059.1|refseq:XP_005265463.1|refseq:XP_006713368.1|ensembl:ENSG00000168268(gene)|ensembl:ENST00000307076(transcript)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:nfT/9N1bWVadX70eY1G0GS9pS9U9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:jzAQ6o1u9znWJotHUSZVF5Z5uGM false sufficient binding region:302-462 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification) uniprotkb:Q15773 uniprotkb:Q16082 intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317 intact:EBI-739395|uniprotkb:Q6I9U7|ensembl:ENSP00000302476 psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short) psi-mi:hspb2_human(display_long)|uniprotkb:HSPB2(gene name)|psi-mi:HSPB2(display_short)|uniprotkb:DMPK-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Grose et al. (2014) pubmed:26465331|doi:10.1371/journal.pone.0133994|imex:IM-25814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-15488218|imex:IM-25814-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773 interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008047"(enzyme activator activity)|rcsb pdb:6F2R|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000170276(gene)|ensembl:ENST00000304298(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001532.1 - - - figure legend:Table 2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/06/15 2017/08/10 rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606 rogid:FHUFrIT2o4NHAk7OUDGfkA5DnMs9606 rigid:ql4C4ii+GXZqmpTfFOmLqttifME false sufficient binding region:98..98-248..248 - - - psi-mi:"MI:1180"(partial DNA sequence identification) psi-mi:"MI:1180"(partial DNA sequence identification)