#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P68135	uniprotkb:P17555	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name)	psi-mi:"MI:0020"(transmission electron microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181286|imex:IM-25156-3|dip:DIP-200577E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695	psi-mi:"MI:0465"(dip)	-	crc64:0EB4D41205E2D464	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292	rigid:94i3OcI6RQ01dIlWHZkQWhKpiOM	false	-	sufficient binding region:1-259	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68135	uniprotkb:P53250	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181286|imex:IM-25156-3|dip:DIP-200577E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250	psi-mi:"MI:0465"(dip)	-	crc64:D9213BBB2D953DBD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rogid:dRJKUwolfd9OK7V77leZs+qODHc559292	rigid:94i3OcI6RQ01dIlWHZkQWhKpiOM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53250	uniprotkb:P68135	intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181267|imex:IM-25156-2|dip:DIP-200575E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	crc64:D9213BBB2D953DBD	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:dRJKUwolfd9OK7V77leZs+qODHc559292	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:nkDp3Aj7LLQJVJHTd+SknQNIHME	false	-	oregon green label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68135	uniprotkb:P68135	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181251|imex:IM-25156-1|dip:DIP-87838E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:TEHkhNh/B/C/FJ5BKfvKPB7VQNs	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68135	uniprotkb:P68135	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181359|imex:IM-25156-7|dip:DIP-87838E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:TEHkhNh/B/C/FJ5BKfvKPB7VQNs	false	oregon green label:?-?	oregon green label:?-?	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53250	uniprotkb:P68135	intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181377|imex:IM-25156-8|dip:DIP-200575E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	crc64:D9213BBB2D953DBD	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:dRJKUwolfd9OK7V77leZs+qODHc559292	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:nkDp3Aj7LLQJVJHTd+SknQNIHME	false	sufficient binding region:305-332	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17555	uniprotkb:P17555	intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W	intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W	psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name)	psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name)	psi-mi:"MI:0020"(transmission electron microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181396|imex:IM-25156-9|dip:DIP-1177E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695	refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695	psi-mi:"MI:0465"(dip)	crc64:0EB4D41205E2D464	crc64:0EB4D41205E2D464	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292	rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292	rigid:odV9thFqDiELZYpTAcyTIIDuknc	false	sufficient binding region:1-259	sufficient binding region:1-259	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03048	uniprotkb:P68135	intact:EBI-4853|uniprotkb:Q05307|uniprotkb:Q2XN65|uniprotkb:D6VXV8|ensemblfungi:YLL050C	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:cofi_yeast(display_long)|uniprotkb:COF1(gene name)|psi-mi:COF1(display_short)|uniprotkb:YLL050C(locus name)|uniprotkb:L0596(orf name)|uniprotkb:Actin-depolymerizing factor 1(gene name synonym)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181340|imex:IM-25156-6|dip:DIP-196848E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013050.1|sgd:S000003973|dip:DIP-197N|mint:Q03048|ensemblfungi:YLL050C(gene)|ensemblfungi:YLL050C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|rcsb pdb:1CFY|rcsb pdb:1COF|rcsb pdb:1QPV|rcsb pdb:4KED|rcsb pdb:4KEE|rcsb pdb:4KEF	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	crc64:7A03747B0F21F22D	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:WPkQGpwwU4If0KSsn2IHw6z5L0E559292	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:t0U4HKOeNVYoMZvpCJkYEw4bNmc	false	-	oregon green label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17555	uniprotkb:P68135	intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181414|imex:IM-25156-10|dip:DIP-200576E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	crc64:0EB4D41205E2D464	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:OEkmHsXJt/EnO3RF2sI74MC0G8s	false	sufficient binding region:1-259	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03048	uniprotkb:P68135	intact:EBI-4853|uniprotkb:Q05307|uniprotkb:Q2XN65|uniprotkb:D6VXV8|ensemblfungi:YLL050C	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:cofi_yeast(display_long)|uniprotkb:COF1(gene name)|psi-mi:COF1(display_short)|uniprotkb:YLL050C(locus name)|uniprotkb:L0596(orf name)|uniprotkb:Actin-depolymerizing factor 1(gene name synonym)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181306|imex:IM-25156-4|dip:DIP-196848E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013050.1|sgd:S000003973|dip:DIP-197N|mint:Q03048|ensemblfungi:YLL050C(gene)|ensemblfungi:YLL050C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|rcsb pdb:1CFY|rcsb pdb:1COF|rcsb pdb:1QPV|rcsb pdb:4KED|rcsb pdb:4KEE|rcsb pdb:4KEF	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	crc64:7A03747B0F21F22D	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:WPkQGpwwU4If0KSsn2IHw6z5L0E559292	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:t0U4HKOeNVYoMZvpCJkYEw4bNmc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53250	uniprotkb:P68135	intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181323|imex:IM-25156-5|dip:DIP-200575E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	crc64:D9213BBB2D953DBD	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:dRJKUwolfd9OK7V77leZs+qODHc559292	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:nkDp3Aj7LLQJVJHTd+SknQNIHME	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53250	uniprotkb:P68135	intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym)	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181433|imex:IM-25156-11|dip:DIP-200575E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	psi-mi:"MI:0465"(dip)	crc64:D9213BBB2D953DBD	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:dRJKUwolfd9OK7V77leZs+qODHc559292	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rigid:nkDp3Aj7LLQJVJHTd+SknQNIHME	false	-	oregon green label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53250	uniprotkb:P17555	intact:EBI-19663|uniprotkb:D6VUL2|ensemblfungi:YGR080W	intact:EBI-4024|uniprotkb:D6W144|ensemblfungi:YNL138W	psi-mi:twf1_yeast(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:YGR080W(locus name)|uniprotkb:Twinfilin-A(gene name synonym)	psi-mi:cap_yeast(display_long)|uniprotkb:SRV2(gene name)|psi-mi:SRV2(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:YNL138W(locus name)|uniprotkb:N1210(orf name)|uniprotkb:N1838(orf name)	psi-mi:"MI:0020"(transmission electron microscopy)	Johnston et al. (2015)	pubmed:26458246|doi:10.1038/ncb3252|imex:IM-25156	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16181452|imex:IM-25156-12|dip:DIP-126690E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003312|ensemblfungi:YGR080W(gene)|ensemblfungi:YGR080W_mRNA(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|refseq:NP_011594.3|dip:DIP-2202N|mint:P53250	refseq:NP_014261.1|sgd:S000005082|dip:DIP-77N|ensemblfungi:YNL138W(gene)|ensemblfungi:YNL138W_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|mint:P17555|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0051014"(actin filament severing)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|rcsb pdb:1K4Z|rcsb pdb:1KQ5|reactome:R-SCE-6798695	psi-mi:"MI:0465"(dip)	crc64:D9213BBB2D953DBD	crc64:0EB4D41205E2D464	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:dRJKUwolfd9OK7V77leZs+qODHc559292	rogid:3Fs9g+L5RnbkqYThVpOvSFrZoJ8559292	rigid:h6hkoHUW8tRGVVE+RDmgfFtoq1M	false	-	sufficient binding region:1-259	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)