#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02948 uniprotkb:P22219 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-20347|uniprotkb:D6VQ98|ensemblfungi:YBR097W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps15_yeast(display_long)|uniprotkb:VPS15(gene name)|psi-mi:VPS15(display_short)|uniprotkb:GRD8(gene name synonym)|uniprotkb:VPL19(gene name synonym)|uniprotkb:YBR0825(orf name)|uniprotkb:YBR097W(locus name)|uniprotkb:VAC4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 15(gene name synonym)|uniprotkb:Golgi-retention defective mutant protein 8(gene name synonym) psi-mi:"MI:0067"(light scattering) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180612|imex:IM-24747-2|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ refseq:NP_009655.2|sgd:S000000301|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071561"(nucleus-vacuole junction)|ensemblfungi:YBR097W(gene)|go:"GO:0106310"(protein serine kinase activity)|ensemblfungi:YBR097W_mRNA(transcript)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|rcsb pdb:3GRE|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|dip:DIP-814N|mint:P22219 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:247EBA5531E41FFB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:bDKA6IlevNTmtSQqleAbkY7/eAI559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:P22543 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-20405|uniprotkb:D6VYN8|ensemblfungi:YLR240W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps34_yeast(display_long)|uniprotkb:VPS34(gene name)|psi-mi:VPS34(display_short)|uniprotkb:END12(gene name synonym)|uniprotkb:PEP15(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 34(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 15(gene name synonym)|uniprotkb:VPL7(gene name synonym)|uniprotkb:VPT29(gene name synonym)|uniprotkb:L9672.10(orf name)|uniprotkb:YLR240W(locus name) psi-mi:"MI:0067"(light scattering) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180612|imex:IM-24747-2|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ refseq:NP_013341.1|sgd:S000004230|ensemblfungi:YLR240W(gene)|ensemblfungi:YLR240W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|dip:DIP-97N|mint:P22543 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:806E3404EF260287 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:a8TnZYg+pKpfjIhB9uInf8Y0uOw559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:Q05919 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:"MI:0067"(light scattering) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180612|imex:IM-24747-2|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:70141E084D185015 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:P22219 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-20347|uniprotkb:D6VQ98|ensemblfungi:YBR097W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps15_yeast(display_long)|uniprotkb:VPS15(gene name)|psi-mi:VPS15(display_short)|uniprotkb:GRD8(gene name synonym)|uniprotkb:VPL19(gene name synonym)|uniprotkb:YBR0825(orf name)|uniprotkb:YBR097W(locus name)|uniprotkb:VAC4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 15(gene name synonym)|uniprotkb:Golgi-retention defective mutant protein 8(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180593|imex:IM-24747-1|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ refseq:NP_009655.2|sgd:S000000301|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071561"(nucleus-vacuole junction)|ensemblfungi:YBR097W(gene)|go:"GO:0106310"(protein serine kinase activity)|ensemblfungi:YBR097W_mRNA(transcript)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|rcsb pdb:3GRE|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|dip:DIP-814N|mint:P22219 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:247EBA5531E41FFB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:bDKA6IlevNTmtSQqleAbkY7/eAI559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:P22543 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-20405|uniprotkb:D6VYN8|ensemblfungi:YLR240W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps34_yeast(display_long)|uniprotkb:VPS34(gene name)|psi-mi:VPS34(display_short)|uniprotkb:END12(gene name synonym)|uniprotkb:PEP15(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 34(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 15(gene name synonym)|uniprotkb:VPL7(gene name synonym)|uniprotkb:VPT29(gene name synonym)|uniprotkb:L9672.10(orf name)|uniprotkb:YLR240W(locus name) psi-mi:"MI:0114"(x-ray crystallography) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180593|imex:IM-24747-1|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ refseq:NP_013341.1|sgd:S000004230|ensemblfungi:YLR240W(gene)|ensemblfungi:YLR240W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|dip:DIP-97N|mint:P22543 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:806E3404EF260287 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:a8TnZYg+pKpfjIhB9uInf8Y0uOw559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:Q05919 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:"MI:0114"(x-ray crystallography) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180593|imex:IM-24747-1|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:70141E084D185015 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:Q05919 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:"MI:0067"(light scattering) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16180631|imex:IM-24747-3|dip:DIP-83093E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:70141E084D185015 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rigid:QExqx/5VrerPFd9I6DITyXS/o7k false sufficient binding region:1-215 sufficient binding region:1-212 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:Q05919 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:"MI:0096"(pull down) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180652|imex:IM-24747-4|dip:DIP-83093E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:70141E084D185015 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rigid:QExqx/5VrerPFd9I6DITyXS/o7k false - zz tag:n-n - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q05919 uniprotkb:Q02948 intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:"MI:0096"(pull down) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16180690|imex:IM-24747-6|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ psi-mi:"MI:0465"(dip) crc64:70141E084D185015 crc64:4BA74B614CABE1C0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false zz tag:n-n - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q05919 uniprotkb:P22219 intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W intact:EBI-20347|uniprotkb:D6VQ98|ensemblfungi:YBR097W psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:vps15_yeast(display_long)|uniprotkb:VPS15(gene name)|psi-mi:VPS15(display_short)|uniprotkb:GRD8(gene name synonym)|uniprotkb:VPL19(gene name synonym)|uniprotkb:YBR0825(orf name)|uniprotkb:YBR097W(locus name)|uniprotkb:VAC4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 15(gene name synonym)|uniprotkb:Golgi-retention defective mutant protein 8(gene name synonym) psi-mi:"MI:0096"(pull down) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16180690|imex:IM-24747-6|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 refseq:NP_009655.2|sgd:S000000301|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071561"(nucleus-vacuole junction)|ensemblfungi:YBR097W(gene)|go:"GO:0106310"(protein serine kinase activity)|ensemblfungi:YBR097W_mRNA(transcript)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|rcsb pdb:3GRE|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|dip:DIP-814N|mint:P22219 psi-mi:"MI:0465"(dip) crc64:70141E084D185015 crc64:247EBA5531E41FFB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rogid:bDKA6IlevNTmtSQqleAbkY7/eAI559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false zz tag:n-n - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q05919 uniprotkb:P22543 intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W intact:EBI-20405|uniprotkb:D6VYN8|ensemblfungi:YLR240W psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:vps34_yeast(display_long)|uniprotkb:VPS34(gene name)|psi-mi:VPS34(display_short)|uniprotkb:END12(gene name synonym)|uniprotkb:PEP15(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 34(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 15(gene name synonym)|uniprotkb:VPL7(gene name synonym)|uniprotkb:VPT29(gene name synonym)|uniprotkb:L9672.10(orf name)|uniprotkb:YLR240W(locus name) psi-mi:"MI:0096"(pull down) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16180690|imex:IM-24747-6|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 refseq:NP_013341.1|sgd:S000004230|ensemblfungi:YLR240W(gene)|ensemblfungi:YLR240W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|dip:DIP-97N|mint:P22543 psi-mi:"MI:0465"(dip) crc64:70141E084D185015 crc64:806E3404EF260287 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rogid:a8TnZYg+pKpfjIhB9uInf8Y0uOw559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false zz tag:n-n - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q02948 uniprotkb:P22219 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-20347|uniprotkb:D6VQ98|ensemblfungi:YBR097W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps15_yeast(display_long)|uniprotkb:VPS15(gene name)|psi-mi:VPS15(display_short)|uniprotkb:GRD8(gene name synonym)|uniprotkb:VPL19(gene name synonym)|uniprotkb:YBR0825(orf name)|uniprotkb:YBR097W(locus name)|uniprotkb:VAC4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 15(gene name synonym)|uniprotkb:Golgi-retention defective mutant protein 8(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180671|imex:IM-24747-5|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ refseq:NP_009655.2|sgd:S000000301|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071561"(nucleus-vacuole junction)|ensemblfungi:YBR097W(gene)|go:"GO:0106310"(protein serine kinase activity)|ensemblfungi:YBR097W_mRNA(transcript)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|rcsb pdb:3GRE|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|dip:DIP-814N|mint:P22219 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:247EBA5531E41FFB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:bDKA6IlevNTmtSQqleAbkY7/eAI559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:P22543 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-20405|uniprotkb:D6VYN8|ensemblfungi:YLR240W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps34_yeast(display_long)|uniprotkb:VPS34(gene name)|psi-mi:VPS34(display_short)|uniprotkb:END12(gene name synonym)|uniprotkb:PEP15(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 34(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 15(gene name synonym)|uniprotkb:VPL7(gene name synonym)|uniprotkb:VPT29(gene name synonym)|uniprotkb:L9672.10(orf name)|uniprotkb:YLR240W(locus name) psi-mi:"MI:0071"(molecular sieving) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180671|imex:IM-24747-5|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ refseq:NP_013341.1|sgd:S000004230|ensemblfungi:YLR240W(gene)|ensemblfungi:YLR240W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|dip:DIP-97N|mint:P22543 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:806E3404EF260287 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:a8TnZYg+pKpfjIhB9uInf8Y0uOw559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:Q05919 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:"MI:0071"(molecular sieving) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16180671|imex:IM-24747-5|dip:DIP-106369E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:70141E084D185015 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rigid:zzkLj6zGz+Yy+9nKYuODyrOyrU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02948 uniprotkb:Q05919 intact:EBI-2670|uniprotkb:D6W3P7|ensemblfungi:YPL120W intact:EBI-29972|uniprotkb:Q6B1J7|uniprotkb:D6VYZ7|ensemblfungi:YLR360W psi-mi:becn1_yeast(display_long)|uniprotkb:VPS30(gene name)|psi-mi:VPS30(display_short)|uniprotkb:APG6(gene name synonym)|uniprotkb:VPT30(gene name synonym)|uniprotkb:YPL120W(locus name)|uniprotkb:LPH7(orf name)|uniprotkb:ATG6(gene name synonym)|uniprotkb:Autophagy-related protein 6(gene name synonym) psi-mi:vps38_yeast(display_long)|uniprotkb:VPS38(gene name)|psi-mi:VPS38(display_short)|uniprotkb:VPL17(gene name synonym)|uniprotkb:YLR360W(locus name)|uniprotkb:L8039.11(orf name) psi-mi:"MI:0071"(molecular sieving) Rostislavleva et al. (2015) pubmed:26450213|doi:10.1126/science.aac7365|imex:IM-24747 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16180711|imex:IM-24747-7|dip:DIP-83093E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015205.1|sgd:S000006041|reactome:R-SCE-1632852|dip:DIP-2961N|ensemblfungi:YPL120W(gene)|ensemblfungi:YPL120W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|rcsb pdb:3VP7|rcsb pdb:5DFZ sgd:S000004352|refseq:NP_013464.3|dip:DIP-8809N|mint:Q05919|ensemblfungi:YLR360W(gene)|ensemblfungi:YLR360W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR040939|rcsb pdb:5DFZ|reactome:R-SCE-1632852 psi-mi:"MI:0465"(dip) crc64:4BA74B614CABE1C0 crc64:70141E084D185015 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:FrJZDpz1EeDouNi0FVJr5NVU3NY559292 rogid:J13HZljzRxl6p0wukZg3YXJn6+w559292 rigid:QExqx/5VrerPFd9I6DITyXS/o7k false sufficient binding region:1-215 sufficient binding region:1-212 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)