#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9QUK4	uniprotkb:Q3UP24	intact:EBI-15944068|ensembl:ENSMUSP00000070827|ensembl:ENSMUSP00000113890|uniprotkb:A9C470|uniprotkb:O09124|uniprotkb:Q9R030	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:bir1b_mouse(display_long)|uniprotkb:Naip2(gene name)|psi-mi:Naip2(display_short)|uniprotkb:Birc1b(gene name synonym)|uniprotkb:Naip-rs6(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 2(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180170|imex:IM-25183-1|dip:DIP-200659E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000078945(gene)|ensembl:ENSMUST00000067975(transcript)|ensembl:ENSMUST00000117913(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0046872"(metal ion binding)|dip:DIP-59160N|refseq:NP_001119654.1|refseq:NP_035002.2	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:ABA+SvqyqCEVHGRgvxA0iSaZpng10090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:JeyjUh1SB/4NEroM/aNCB82xRVs	false	-	sufficient binding region:93-1024	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QUK4	uniprotkb:P41785	intact:EBI-15944068|ensembl:ENSMUSP00000070827|ensembl:ENSMUSP00000113890|uniprotkb:A9C470|uniprotkb:O09124|uniprotkb:Q9R030	intact:EBI-15880089|ensemblbacteria:AAL21752	psi-mi:bir1b_mouse(display_long)|uniprotkb:Naip2(gene name)|psi-mi:Naip2(display_short)|uniprotkb:Birc1b(gene name synonym)|uniprotkb:Naip-rs6(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 2(gene name synonym)	psi-mi:prgj_salty(display_long)|uniprotkb:prgJ(gene name)|psi-mi:prgJ(display_short)|uniprotkb:STM2872(locus name)	psi-mi:"MI:0020"(transmission electron microscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180170|imex:IM-25183-1|dip:DIP-200659E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000078945(gene)|ensembl:ENSMUST00000067975(transcript)|ensembl:ENSMUST00000117913(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0046872"(metal ion binding)|dip:DIP-59160N|refseq:NP_001119654.1|refseq:NP_035002.2	ensemblbacteria:AAL21752(transcript)|ensemblbacteria:STM2872(gene)|go:"GO:0015031"(protein transport)|rcsb pdb:6PEP|rcsb pdb:6Q15|rcsb pdb:6Q16|rcsb pdb:7AGX|rcsb pdb:7AH9|rcsb pdb:7AHI|reactome:R-HSA-844623|refseq:NP_461793.1|refseq:WP_000020431.1|dip:DIP-59556N	psi-mi:"MI:0465"(dip)	-	crc64:7AC04EF792D72598	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:ABA+SvqyqCEVHGRgvxA0iSaZpng10090	rogid:CCDXFTTW8zNCRoWDvrQOveU7E5g99287	rigid:JeyjUh1SB/4NEroM/aNCB82xRVs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q3UP24	uniprotkb:Q3UP24	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180221|imex:IM-25183-3|dip:DIP-200468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:OiMuYxH6LPhS9jlwHZo8/0GDTT8	false	sufficient binding region:93-1024	sufficient binding region:93-1024	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R016	uniprotkb:Q3UP24	intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180190|imex:IM-25183-2|dip:DIP-199798E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:R9fGjgZ0oGOSQSlwxxlRtvYjH9w	false	flag tag:n-n	sufficient binding region:93-1024|maltose binding protein tag:n-n|mutation decreasing interaction strength:285-285|mutation decreasing interaction strength:289-289,288-288	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9R016	uniprotkb:P06179	intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029	intact:EBI-2011501|uniprotkb:P97160|uniprotkb:Q02871|uniprotkb:Q56088|ensemblbacteria:AAL20871	psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym)	psi-mi:flic_salty(display_long)|uniprotkb:fliC(gene name)|psi-mi:fliC(display_short)|uniprotkb:flaF(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:Phase 1-I flagellin(gene name synonym)|uniprotkb:STM1959(locus name)	psi-mi:"MI:0020"(transmission electron microscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180239|imex:IM-25183-4|dip:DIP-200469E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2	refseq:NP_460912.1|refseq:WP_000079805.1|dip:DIP-43768N|mint:P06179|ensemblbacteria:AAL20871(transcript)|ensemblbacteria:STM1959(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR014981(Flagellin D3)|interpro:IPR042187|rcsb pdb:1IO1|rcsb pdb:1P95|rcsb pdb:1UCU|rcsb pdb:3A5X|rcsb pdb:5YUD|rcsb pdb:6CH3|reactome:R-GGA-433822|reactome:R-GGA-451534|reactome:R-GGA-977240|reactome:R-HSA-844623	psi-mi:"MI:0465"(dip)	-	crc64:4BD7849FA3B936BA	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090	rogid:0JWcURU8Owt3IW+XBPx9sRk/Ou899287	rigid:60AoeF4tBXAw7T4ZOZPpun4hJME	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R016	uniprotkb:Q3UP24	intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180239|imex:IM-25183-4|dip:DIP-200469E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:60AoeF4tBXAw7T4ZOZPpun4hJME	false	-	sufficient binding region:93-1024	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q3UP24	uniprotkb:Q9R016	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180259|imex:IM-25183-5|dip:DIP-200469E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090	rigid:60AoeF4tBXAw7T4ZOZPpun4hJME	false	sufficient binding region:93-1024|maltose binding protein tag:n-n	flag tag:n-n|mutation decreasing interaction strength:590-590,587-587	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q3UP24	uniprotkb:P06179	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	intact:EBI-2011501|uniprotkb:P97160|uniprotkb:Q02871|uniprotkb:Q56088|ensemblbacteria:AAL20871	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:flic_salty(display_long)|uniprotkb:fliC(gene name)|psi-mi:fliC(display_short)|uniprotkb:flaF(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:Phase 1-I flagellin(gene name synonym)|uniprotkb:STM1959(locus name)	psi-mi:"MI:0096"(pull down)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180259|imex:IM-25183-5|dip:DIP-200469E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	refseq:NP_460912.1|refseq:WP_000079805.1|dip:DIP-43768N|mint:P06179|ensemblbacteria:AAL20871(transcript)|ensemblbacteria:STM1959(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR014981(Flagellin D3)|interpro:IPR042187|rcsb pdb:1IO1|rcsb pdb:1P95|rcsb pdb:1UCU|rcsb pdb:3A5X|rcsb pdb:5YUD|rcsb pdb:6CH3|reactome:R-GGA-433822|reactome:R-GGA-451534|reactome:R-GGA-977240|reactome:R-HSA-844623	psi-mi:"MI:0465"(dip)	-	crc64:4BD7849FA3B936BA	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rogid:0JWcURU8Owt3IW+XBPx9sRk/Ou899287	rigid:60AoeF4tBXAw7T4ZOZPpun4hJME	false	sufficient binding region:93-1024|maltose binding protein tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q3UP24	uniprotkb:Q3UP24	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180340|imex:IM-25183-8|dip:DIP-200468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:OiMuYxH6LPhS9jlwHZo8/0GDTT8	false	sufficient binding region:1-88	sufficient binding region:1-88	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QUK4	uniprotkb:Q3UP24	intact:EBI-15944068|ensembl:ENSMUSP00000070827|ensembl:ENSMUSP00000113890|uniprotkb:A9C470|uniprotkb:O09124|uniprotkb:Q9R030	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:bir1b_mouse(display_long)|uniprotkb:Naip2(gene name)|psi-mi:Naip2(display_short)|uniprotkb:Birc1b(gene name synonym)|uniprotkb:Naip-rs6(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 2(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180320|imex:IM-25183-7|dip:DIP-200659E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000078945(gene)|ensembl:ENSMUST00000067975(transcript)|ensembl:ENSMUST00000117913(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0046872"(metal ion binding)|dip:DIP-59160N|refseq:NP_001119654.1|refseq:NP_035002.2	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:ABA+SvqyqCEVHGRgvxA0iSaZpng10090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:JeyjUh1SB/4NEroM/aNCB82xRVs	false	-	sufficient binding region:93-1024	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QUK4	uniprotkb:P41785	intact:EBI-15944068|ensembl:ENSMUSP00000070827|ensembl:ENSMUSP00000113890|uniprotkb:A9C470|uniprotkb:O09124|uniprotkb:Q9R030	intact:EBI-15880089|ensemblbacteria:AAL21752	psi-mi:bir1b_mouse(display_long)|uniprotkb:Naip2(gene name)|psi-mi:Naip2(display_short)|uniprotkb:Birc1b(gene name synonym)|uniprotkb:Naip-rs6(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 2(gene name synonym)	psi-mi:prgj_salty(display_long)|uniprotkb:prgJ(gene name)|psi-mi:prgJ(display_short)|uniprotkb:STM2872(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180320|imex:IM-25183-7|dip:DIP-200659E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000078945(gene)|ensembl:ENSMUST00000067975(transcript)|ensembl:ENSMUST00000117913(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0046872"(metal ion binding)|dip:DIP-59160N|refseq:NP_001119654.1|refseq:NP_035002.2	ensemblbacteria:AAL21752(transcript)|ensemblbacteria:STM2872(gene)|go:"GO:0015031"(protein transport)|rcsb pdb:6PEP|rcsb pdb:6Q15|rcsb pdb:6Q16|rcsb pdb:7AGX|rcsb pdb:7AH9|rcsb pdb:7AHI|reactome:R-HSA-844623|refseq:NP_461793.1|refseq:WP_000020431.1|dip:DIP-59556N	psi-mi:"MI:0465"(dip)	-	crc64:7AC04EF792D72598	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/08	2017/08/10	rogid:ABA+SvqyqCEVHGRgvxA0iSaZpng10090	rogid:CCDXFTTW8zNCRoWDvrQOveU7E5g99287	rigid:JeyjUh1SB/4NEroM/aNCB82xRVs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q3UP24	uniprotkb:Q9R016	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180289|imex:IM-25183-6|dip:DIP-200469E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090	rigid:60AoeF4tBXAw7T4ZOZPpun4hJME	false	sufficient binding region:93-1024|maltose binding protein tag:n-n|mutation decreasing interaction strength:125-125,123-123,122-122	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q3UP24	uniprotkb:P06179	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	intact:EBI-2011501|uniprotkb:P97160|uniprotkb:Q02871|uniprotkb:Q56088|ensemblbacteria:AAL20871	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:flic_salty(display_long)|uniprotkb:fliC(gene name)|psi-mi:fliC(display_short)|uniprotkb:flaF(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:Phase 1-I flagellin(gene name synonym)|uniprotkb:STM1959(locus name)	psi-mi:"MI:0096"(pull down)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180289|imex:IM-25183-6|dip:DIP-200469E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	refseq:NP_460912.1|refseq:WP_000079805.1|dip:DIP-43768N|mint:P06179|ensemblbacteria:AAL20871(transcript)|ensemblbacteria:STM1959(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR014981(Flagellin D3)|interpro:IPR042187|rcsb pdb:1IO1|rcsb pdb:1P95|rcsb pdb:1UCU|rcsb pdb:3A5X|rcsb pdb:5YUD|rcsb pdb:6CH3|reactome:R-GGA-433822|reactome:R-GGA-451534|reactome:R-GGA-977240|reactome:R-HSA-844623	psi-mi:"MI:0465"(dip)	-	crc64:4BD7849FA3B936BA	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2018/04/30	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rogid:0JWcURU8Owt3IW+XBPx9sRk/Ou899287	rigid:60AoeF4tBXAw7T4ZOZPpun4hJME	false	sufficient binding region:93-1024|maltose binding protein tag:n-n|mutation decreasing interaction strength:125-125,123-123,122-122	his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P29452	uniprotkb:Q3UP24	intact:EBI-489700|ensembl:ENSMUSP00000027015	intact:EBI-16006652|ensembl:ENSMUSP00000059637|uniprotkb:Q3TAU8	psi-mi:casp1_mouse(display_long)|uniprotkb:Interleukin-1 beta convertase(gene name synonym)|uniprotkb:Interleukin-1 beta-converting enzyme(gene name synonym)|uniprotkb:p45(gene name synonym)|uniprotkb:Casp1(gene name)|psi-mi:Casp1(display_short)|uniprotkb:Il1bc(gene name synonym)	psi-mi:nlrc4_mouse(display_long)|uniprotkb:Nlrc4(gene name)|psi-mi:Nlrc4(display_short)|uniprotkb:Card12(gene name synonym)|uniprotkb:Ipaf(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Zhang et al. (2015)	pubmed:26449474|doi:10.1126/science.aac5789|imex:IM-25183	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16180358|imex:IM-25183-9|dip:DIP-190021E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033937.2|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0070269"(pyroptosis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:0097179"(protease inhibitor complex)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0140447"(cytokine precursor processing)|go:"GO:0140448"(signaling receptor ligand precursor processing)|go:"GO:1901998"(toxin transport)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|reactome:R-MMU-168638|reactome:R-MMU-448706|reactome:R-MMU-5620971|ensembl:ENSMUSG00000025888(gene)|ensembl:ENSMUST00000027015(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007613"(memory)|go:"GO:0008233"(peptidase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019900"(kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|dip:DIP-34659N	interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR040535|interpro:IPR042220|rcsb pdb:3JBL|rcsb pdb:4KXF|rcsb pdb:5AJ2|rcsb pdb:6B5B|interpro:IPR007111(NACHT nucleoside triphosphatase)|ensembl:ENSMUSG00000039193(gene)|ensembl:ENSMUST00000052124(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|go:"GO:0089720"(caspase binding)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|refseq:NP_001028539.1|refseq:XP_006524409.1|refseq:XP_017172979.1|refseq:XP_017172980.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:XhG0cS+c25k1ktN7Kbn4d0BS14810090	rogid:EwJUZJSasbk43tsDLlfJqxC2oec10090	rigid:mTrgFo50fur1nPKibA9l1/jGDKA	false	sufficient binding region:1-91|tetramethyl rhodamine label:?-?	sufficient binding region:1-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)