#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q746J7 uniprotkb:Q746J7 intact:EBI-16179013|ensemblbacteria:AAS82386 intact:EBI-16179013|ensemblbacteria:AAS82386 psi-mi:q746j7_thet2(display_long)|uniprotkb:TT_P0056(locus name) psi-mi:q746j7_thet2(display_long)|uniprotkb:TT_P0056(locus name) psi-mi:"MI:0114"(x-ray crystallography) Jost et al. (2015) pubmed:26416754|doi:10.1038/nature14950|imex:IM-24910 taxid:262724(thet2)|taxid:262724("Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)") taxid:262724(thet2)|taxid:262724("Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16179033|imex:IM-24910-1|dip:DIP-199908E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAS82386(transcript)|ensemblbacteria:TT_P0056(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031419"(cobalamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|interpro:IPR003759("Methionine synthase, cobalamin (vitamin B12)-binding module, cap")|interpro:IPR006158("Cobalamin (vitamin B12)-binding")|interpro:IPR009061(Putative DNA binding)|interpro:IPR036594|interpro:IPR036724|rcsb pdb:3WHP|rcsb pdb:5C8A|rcsb pdb:5C8D|rcsb pdb:5C8E|rcsb pdb:5C8F|refseq:WP_011174503.1|dip:DIP-61774N ensemblbacteria:AAS82386(transcript)|ensemblbacteria:TT_P0056(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031419"(cobalamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|interpro:IPR003759("Methionine synthase, cobalamin (vitamin B12)-binding module, cap")|interpro:IPR006158("Cobalamin (vitamin B12)-binding")|interpro:IPR009061(Putative DNA binding)|interpro:IPR036594|interpro:IPR036724|rcsb pdb:3WHP|rcsb pdb:5C8A|rcsb pdb:5C8D|rcsb pdb:5C8E|rcsb pdb:5C8F|refseq:WP_011174503.1|dip:DIP-61774N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:BYV7pqrMudZXkNkqoCaf3PzP6jU262724 rogid:BYV7pqrMudZXkNkqoCaf3PzP6jU262724 rigid:7KBFL12Gpaj/OErFUSeWj++IlUw false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q746J7 uniprotkb:Q746J7 intact:EBI-16179013|ensemblbacteria:AAS82386 intact:EBI-16179013|ensemblbacteria:AAS82386 psi-mi:q746j7_thet2(display_long)|uniprotkb:TT_P0056(locus name) psi-mi:q746j7_thet2(display_long)|uniprotkb:TT_P0056(locus name) psi-mi:"MI:0071"(molecular sieving) Jost et al. (2015) pubmed:26416754|doi:10.1038/nature14950|imex:IM-24910 taxid:262724(thet2)|taxid:262724("Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)") taxid:262724(thet2)|taxid:262724("Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16179049|imex:IM-24910-2|dip:DIP-199908E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAS82386(transcript)|ensemblbacteria:TT_P0056(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031419"(cobalamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|interpro:IPR003759("Methionine synthase, cobalamin (vitamin B12)-binding module, cap")|interpro:IPR006158("Cobalamin (vitamin B12)-binding")|interpro:IPR009061(Putative DNA binding)|interpro:IPR036594|interpro:IPR036724|rcsb pdb:3WHP|rcsb pdb:5C8A|rcsb pdb:5C8D|rcsb pdb:5C8E|rcsb pdb:5C8F|refseq:WP_011174503.1|dip:DIP-61774N ensemblbacteria:AAS82386(transcript)|ensemblbacteria:TT_P0056(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031419"(cobalamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|interpro:IPR003759("Methionine synthase, cobalamin (vitamin B12)-binding module, cap")|interpro:IPR006158("Cobalamin (vitamin B12)-binding")|interpro:IPR009061(Putative DNA binding)|interpro:IPR036594|interpro:IPR036724|rcsb pdb:3WHP|rcsb pdb:5C8A|rcsb pdb:5C8D|rcsb pdb:5C8E|rcsb pdb:5C8F|refseq:WP_011174503.1|dip:DIP-61774N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:BYV7pqrMudZXkNkqoCaf3PzP6jU262724 rogid:BYV7pqrMudZXkNkqoCaf3PzP6jU262724 rigid:7KBFL12Gpaj/OErFUSeWj++IlUw false mutation disrupting interaction strength:142-142|mutation disrupting interaction strength:201-201|mutation decreasing interaction strength:131-131|mutation decreasing interaction strength:141-141|mutation decreasing interaction strength:160-160|mutation decreasing interaction strength:192-192 mutation disrupting interaction strength:142-142|mutation disrupting interaction strength:201-201|mutation decreasing interaction strength:131-131|mutation decreasing interaction strength:141-141|mutation decreasing interaction strength:160-160|mutation decreasing interaction strength:192-192 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)