#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00740	uniprotkb:Q3U4G3	intact:EBI-9640450|uniprotkb:A8K9N4|uniprotkb:Q5JYJ8|uniprotkb:F2RM36|uniprotkb:Q5FBE1|ensembl:ENSP00000218099	intact:EBI-16178491|ensembl:ENSMUSP00000050246|uniprotkb:E9QL73|uniprotkb:Q3TLX5|uniprotkb:Q8K2I0	psi-mi:fa9_human(display_long)|uniprotkb:F9(gene name)|psi-mi:F9(display_short)|uniprotkb:Christmas factor(gene name synonym)|uniprotkb:Plasma thromboplastin component(gene name synonym)	psi-mi:xxlt1_mouse(display_long)|uniprotkb:Xxylt1(gene name)|psi-mi:Xxylt1(display_short)|uniprotkb:"UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase"(gene name synonym)	psi-mi:"MI:1007"(glycosylase assay)	Yu et al. (2015)	pubmed:26414444|doi:10.1038/nchembio.1927|imex:IM-25179	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0559"(glycosylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16178522|imex:IM-25179-1|dip:DIP-200656E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300842.1|refseq:NP_000124.1|dip:DIP-58520N|ensembl:ENSG00000101981(gene)|ensembl:ENST00000218099(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035694|interpro:IPR035972|interpro:IPR043504|rcsb pdb:1CFH|rcsb pdb:1CFI|rcsb pdb:1EDM|rcsb pdb:1IXA|rcsb pdb:1MGX|rcsb pdb:1NL0|rcsb pdb:1RFN|rcsb pdb:2WPH|rcsb pdb:2WPI|rcsb pdb:2WPJ|rcsb pdb:2WPK|rcsb pdb:2WPL|rcsb pdb:2WPM|rcsb pdb:3KCG|rcsb pdb:3LC3|rcsb pdb:3LC5|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|rcsb pdb:4YZU|rcsb pdb:4Z0K|rcsb pdb:4ZAE|rcsb pdb:5EGM|rcsb pdb:5F84|rcsb pdb:5F85|rcsb pdb:5F86|rcsb pdb:5JB8|rcsb pdb:5JB9|rcsb pdb:5JBA|rcsb pdb:5JBB|rcsb pdb:5JBC|rcsb pdb:5TNO|rcsb pdb:5TNT|rcsb pdb:5VYG|rcsb pdb:6MV4|rcsb pdb:6RFK|rcsb pdb:6X5J|rcsb pdb:6X5L|rcsb pdb:6X5P|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|reactome:R-HSA-9673218|reactome:R-HSA-9673221|reactome:R-HSA-9673240|mint:P00740	ensembl:ENSMUSG00000047434(gene)|ensembl:ENSMUST00000055389(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0016266"(O-glycan processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0035252"(UDP-xylosyltransferase activity)|go:"GO:0140560"(xylosyl alpha-1,3-xylosyltransferase activity)|interpro:IPR002495(Glycosyl transferase, family 8)|interpro:IPR029044|interpro:IPR042465|rcsb pdb:4WLG|rcsb pdb:4WLM|rcsb pdb:4WLZ|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|refseq:NP_941028.2|dip:DIP-61862N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:WgF6aC2nvjTyYTwIhMpWd2paXgI9606	rogid:SKbmMc74t1/i47CcXlrQ32hnyn010090	rigid:XkJVnNa3QHOA0sX+/5G34TR2198	false	sufficient binding region:92-130	sufficient binding region:87-392|mutation disrupting interaction rate:330-330|mutation disrupting interaction rate:359-359|mutation decreasing interaction rate:255-255|mutation decreasing interaction rate:326-326|mutation decreasing interaction rate:358-358|mutation decreasing interaction rate:384-384|mutation decreasing interaction rate:257-257|mutation decreasing interaction rate:289-289|mutation decreasing interaction rate:324-324|mutation decreasing interaction rate:325-325	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00740	uniprotkb:Q3U4G3	intact:EBI-9640450|uniprotkb:A8K9N4|uniprotkb:Q5JYJ8|uniprotkb:F2RM36|uniprotkb:Q5FBE1|ensembl:ENSP00000218099	intact:EBI-16178491|ensembl:ENSMUSP00000050246|uniprotkb:E9QL73|uniprotkb:Q3TLX5|uniprotkb:Q8K2I0	psi-mi:fa9_human(display_long)|uniprotkb:F9(gene name)|psi-mi:F9(display_short)|uniprotkb:Christmas factor(gene name synonym)|uniprotkb:Plasma thromboplastin component(gene name synonym)	psi-mi:xxlt1_mouse(display_long)|uniprotkb:Xxylt1(gene name)|psi-mi:Xxylt1(display_short)|uniprotkb:"UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase"(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Yu et al. (2015)	pubmed:26414444|doi:10.1038/nchembio.1927|imex:IM-25179	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16178573|imex:IM-25179-2|dip:DIP-200656E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300842.1|refseq:NP_000124.1|dip:DIP-58520N|ensembl:ENSG00000101981(gene)|ensembl:ENST00000218099(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035694|interpro:IPR035972|interpro:IPR043504|rcsb pdb:1CFH|rcsb pdb:1CFI|rcsb pdb:1EDM|rcsb pdb:1IXA|rcsb pdb:1MGX|rcsb pdb:1NL0|rcsb pdb:1RFN|rcsb pdb:2WPH|rcsb pdb:2WPI|rcsb pdb:2WPJ|rcsb pdb:2WPK|rcsb pdb:2WPL|rcsb pdb:2WPM|rcsb pdb:3KCG|rcsb pdb:3LC3|rcsb pdb:3LC5|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|rcsb pdb:4YZU|rcsb pdb:4Z0K|rcsb pdb:4ZAE|rcsb pdb:5EGM|rcsb pdb:5F84|rcsb pdb:5F85|rcsb pdb:5F86|rcsb pdb:5JB8|rcsb pdb:5JB9|rcsb pdb:5JBA|rcsb pdb:5JBB|rcsb pdb:5JBC|rcsb pdb:5TNO|rcsb pdb:5TNT|rcsb pdb:5VYG|rcsb pdb:6MV4|rcsb pdb:6RFK|rcsb pdb:6X5J|rcsb pdb:6X5L|rcsb pdb:6X5P|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|reactome:R-HSA-9673218|reactome:R-HSA-9673221|reactome:R-HSA-9673240|mint:P00740	ensembl:ENSMUSG00000047434(gene)|ensembl:ENSMUST00000055389(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0016266"(O-glycan processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0035252"(UDP-xylosyltransferase activity)|go:"GO:0140560"(xylosyl alpha-1,3-xylosyltransferase activity)|interpro:IPR002495(Glycosyl transferase, family 8)|interpro:IPR029044|interpro:IPR042465|rcsb pdb:4WLG|rcsb pdb:4WLM|rcsb pdb:4WLZ|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|refseq:NP_941028.2|dip:DIP-61862N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:WgF6aC2nvjTyYTwIhMpWd2paXgI9606	rogid:SKbmMc74t1/i47CcXlrQ32hnyn010090	rigid:XkJVnNa3QHOA0sX+/5G34TR2198	false	sufficient binding region:92-130	sufficient binding region:87-392	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P00740	uniprotkb:Q3U4G3	intact:EBI-9640450|uniprotkb:A8K9N4|uniprotkb:Q5JYJ8|uniprotkb:F2RM36|uniprotkb:Q5FBE1|ensembl:ENSP00000218099	intact:EBI-16178491|ensembl:ENSMUSP00000050246|uniprotkb:E9QL73|uniprotkb:Q3TLX5|uniprotkb:Q8K2I0	psi-mi:fa9_human(display_long)|uniprotkb:F9(gene name)|psi-mi:F9(display_short)|uniprotkb:Christmas factor(gene name synonym)|uniprotkb:Plasma thromboplastin component(gene name synonym)	psi-mi:xxlt1_mouse(display_long)|uniprotkb:Xxylt1(gene name)|psi-mi:Xxylt1(display_short)|uniprotkb:"UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Yu et al. (2015)	pubmed:26414444|doi:10.1038/nchembio.1927|imex:IM-25179	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16178601|imex:IM-25179-3|dip:DIP-200656E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300842.1|refseq:NP_000124.1|dip:DIP-58520N|ensembl:ENSG00000101981(gene)|ensembl:ENST00000218099(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035694|interpro:IPR035972|interpro:IPR043504|rcsb pdb:1CFH|rcsb pdb:1CFI|rcsb pdb:1EDM|rcsb pdb:1IXA|rcsb pdb:1MGX|rcsb pdb:1NL0|rcsb pdb:1RFN|rcsb pdb:2WPH|rcsb pdb:2WPI|rcsb pdb:2WPJ|rcsb pdb:2WPK|rcsb pdb:2WPL|rcsb pdb:2WPM|rcsb pdb:3KCG|rcsb pdb:3LC3|rcsb pdb:3LC5|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|rcsb pdb:4YZU|rcsb pdb:4Z0K|rcsb pdb:4ZAE|rcsb pdb:5EGM|rcsb pdb:5F84|rcsb pdb:5F85|rcsb pdb:5F86|rcsb pdb:5JB8|rcsb pdb:5JB9|rcsb pdb:5JBA|rcsb pdb:5JBB|rcsb pdb:5JBC|rcsb pdb:5TNO|rcsb pdb:5TNT|rcsb pdb:5VYG|rcsb pdb:6MV4|rcsb pdb:6RFK|rcsb pdb:6X5J|rcsb pdb:6X5L|rcsb pdb:6X5P|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|reactome:R-HSA-9673218|reactome:R-HSA-9673221|reactome:R-HSA-9673240|mint:P00740	ensembl:ENSMUSG00000047434(gene)|ensembl:ENSMUST00000055389(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0016266"(O-glycan processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0035252"(UDP-xylosyltransferase activity)|go:"GO:0140560"(xylosyl alpha-1,3-xylosyltransferase activity)|interpro:IPR002495(Glycosyl transferase, family 8)|interpro:IPR029044|interpro:IPR042465|rcsb pdb:4WLG|rcsb pdb:4WLM|rcsb pdb:4WLZ|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|refseq:NP_941028.2|dip:DIP-61862N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:WgF6aC2nvjTyYTwIhMpWd2paXgI9606	rogid:SKbmMc74t1/i47CcXlrQ32hnyn010090	rigid:XkJVnNa3QHOA0sX+/5G34TR2198	false	sufficient binding region:92-130	sufficient binding region:87-392	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)