#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35579 uniprotkb:P70335 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 intact:EBI-989293|uniprotkb:Q8C3G4|uniprotkb:Q8C7H0|ensembl:ENSMUSP00000069549 psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:rock1_mouse(display_long)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 1(gene name synonym)|uniprotkb:p160 ROCK-1(gene name synonym)|uniprotkb:Rock1(gene name)|psi-mi:Rock1(display_short)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Priya et al. (2015) pubmed:26368311|doi:10.1038/ncb3239|imex:IM-25154 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16177805|imex:IM-25154-1|dip:DIP-200572E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N go:"GO:0007159"(leukocyte cell-cell adhesion)|ensembl:ENSMUSG00000024290(gene)|ensembl:ENSMUST00000067947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003383"(apical constriction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0071559"(response to transforming growth factor beta)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037310|mint:P70335|reactome:R-MMU-111465|reactome:R-MMU-3928662|reactome:R-MMU-416482|reactome:R-MMU-416572|reactome:R-MMU-4420097|reactome:R-MMU-5627117|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013407|reactome:R-MMU-9013422|reactome:R-MMU-9696264|interpro:IPR011072(HR1 rho-binding repeat)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032059"(bleb)|go:"GO:0032060"(bleb assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051451"(myoblast migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|refseq:NP_033097.1|refseq:XP_006525788.1|dip:DIP-35521N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 rogid:BIAb7c+Ar8WI6cES/igerUjk1zc10090 rigid:zR2FxTPT40+mGOHDCItuyKG5mNM false - green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13464 uniprotkb:P35579 intact:EBI-876651|uniprotkb:B0YJ91|uniprotkb:Q2KHM4|uniprotkb:Q59GZ4|ensembl:ENSP00000382697 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:rock1_human(display_long)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 1(gene name synonym)|uniprotkb:p160 ROCK-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-35(gene name synonym)|uniprotkb:ROCK1(gene name)|psi-mi:ROCK1(display_short)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase I(gene name synonym) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Priya et al. (2015) pubmed:26368311|doi:10.1038/ncb3239|imex:IM-25154 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16177824|imex:IM-25154-2|dip:DIP-200573E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005397.1|dip:DIP-35645N|ensembl:ENSG00000067900(gene)|ensembl:ENST00000399799(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032059"(bleb)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0051451"(myoblast migration)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037310|mint:Q13464|rcsb pdb:1S1C|rcsb pdb:2ESM|rcsb pdb:2ETK|rcsb pdb:2ETR|rcsb pdb:2V55|rcsb pdb:3D9V|rcsb pdb:3NCZ|rcsb pdb:3NDM|rcsb pdb:3O0Z|rcsb pdb:3TV7|rcsb pdb:3TWJ|rcsb pdb:3V8S|rcsb pdb:4L2W|rcsb pdb:4W7P|rcsb pdb:4YVC|rcsb pdb:4YVE|rcsb pdb:5BML|rcsb pdb:5F5P|rcsb pdb:5HVU|rcsb pdb:5KKS|rcsb pdb:5KKT|rcsb pdb:5UZJ|rcsb pdb:5WNE|rcsb pdb:5WNF|rcsb pdb:5WNG|rcsb pdb:5WNH|rcsb pdb:6E9W|rcsb pdb:7JOU|reactome:R-HSA-111465|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5627117|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013407|reactome:R-HSA-9013422|reactome:R-HSA-9679191|reactome:R-HSA-9696264 refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:1YIjRC+RHWK9pmiq8kSBFiZcll49606 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 rigid:CUqMKz6sIipGk5UCWhq2J8s19b8 false - sufficient binding region:883-1960|green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)