#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y6N7	uniprotkb:O75044	intact:EBI-399762|uniprotkb:Q7Z300|uniprotkb:Q9BUS7|uniprotkb:D3DU36|uniprotkb:B2RXI1|uniprotkb:E9PD49|uniprotkb:Q1RMC7|ensembl:ENSP00000420321	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:robo1_human(display_long)|uniprotkb:ROBO1(gene name)|psi-mi:ROBO1(display_short)|uniprotkb:DUTT1(gene name synonym)|uniprotkb:H-Robo-1(gene name synonym)|uniprotkb:Deleted in U twenty twenty(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177537|imex:IM-25122-1|dip:DIP-200082E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139317.1|refseq:NP_002932.1|refseq:NP_598334.2|ensembl:ENSP00000420321|ensembl:ENST00000467549|ensembl:ENSP00000417992|ensembl:ENST00000495273|ensembl:ENSP00000420637|refseq:XP_006713340.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032986|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2EO9|rcsb pdb:2V9Q|rcsb pdb:2V9R|rcsb pdb:2V9T|rcsb pdb:3WIH|rcsb pdb:4HLJ|rcsb pdb:5O5G|rcsb pdb:5O5I|rcsb pdb:5OPE|rcsb pdb:6A77|rcsb pdb:6A78|ensembl:ENSG00000169855(gene)|ensembl:ENST00000464233(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009986"(cell surface)|refseq:XP_016862472.1|dip:DIP-33034N|rcsb pdb:6A79|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-8985801|reactome:R-HSA-9010553	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2018/01/16	rogid:LLHEVlylzhWB/zr77pQrNizgVsg9606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:w06Av31/ToZg5nQ27R1hAEGeEz0	false	sufficient binding region:1472-1495	sufficient binding region:729-799	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75044	uniprotkb:O75044	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177576|imex:IM-25122-3|dip:DIP-200080E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2018/01/16	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:+D5XqiTE4qYSfwJil/aFO34x8DY	false	sufficient binding region:1-815	sufficient binding region:1-815	-	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O75044	uniprotkb:O75044	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177558|imex:IM-25122-2|dip:DIP-200080E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2018/01/16	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:+D5XqiTE4qYSfwJil/aFO34x8DY	false	sufficient binding region:1-815	sufficient binding region:1-815	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98171-1	uniprotkb:P98171-1	intact:EBI-16177615|ensembl:ENSP00000203786	intact:EBI-16177615|ensembl:ENSP00000203786	psi-mi:p98171-1(display_long)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)	psi-mi:p98171-1(display_long)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177658|imex:IM-25122-7|dip:DIP-200081E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2796462(isoform-parent)|ensembl:ENSG00000089820(gene)|ensembl:ENST00000350060(transcript)	intact:EBI-2796462(isoform-parent)|ensembl:ENSG00000089820(gene)|ensembl:ENST00000350060(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	rigid:4ApRSKMe2c1OmdJ8Wo/tnCG1ToU	false	-	-	-	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q9NQX3	uniprotkb:O75044	intact:EBI-2371891|uniprotkb:Q9H4E9|uniprotkb:Q9P2G2|uniprotkb:Q96KU4|ensembl:ENSP00000312771	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:geph_human(display_long)|uniprotkb:GPHN(gene name)|psi-mi:GPHN(display_short)|uniprotkb:GPH(gene name synonym)|uniprotkb:KIAA1385(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:1247"(microscale thermophoresis)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177674|imex:IM-25122-8|dip:DIP-200083E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019389.1|refseq:NP_065857.1|dip:DIP-41076N|rcsb pdb:1JLJ|reactome:R-HSA-947581|interpro:IPR038987|ensembl:ENSG00000171723(gene)|ensembl:ENST00000315266(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0010038"(response to metal ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018315"(molybdenum incorporation into molybdenum-molybdopterin complex)|go:"GO:0030425"(dendrite)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0061598"(molybdopterin adenylyltransferase activity)|go:"GO:0061599"(molybdopterin molybdotransferase activity)|go:"GO:0072579"(glycine receptor clustering)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0099144"(anchored component of synaptic membrane)|go:"GO:0099572"(postsynaptic specialization)|go:"GO:0099634"(postsynaptic specialization membrane)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR008284(Molybdenum cofactor biosynthesis, conserved site)|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2018/01/16	rogid:iu4Nl7g9dOChbmYok/lo6kjW3pM9606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:t8y4xcczWdt9NPofCHxBY42Qm44	false	sufficient binding region:592-614	sufficient binding region:729-799	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75044	uniprotkb:O75044	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:0104"(static light scattering)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177695|imex:IM-25122-9|dip:DIP-200080E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2018/01/16	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:+D5XqiTE4qYSfwJil/aFO34x8DY	false	sufficient binding region:729-815	sufficient binding region:729-815	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49750	uniprotkb:O75044	intact:EBI-712871|ensembl:ENSP00000324463|uniprotkb:P49752|uniprotkb:Q96I64|uniprotkb:Q9P1V7	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:ylpm1_human(display_long)|uniprotkb:Nuclear protein ZAP3(gene name synonym)|uniprotkb:ZAP113(gene name synonym)|uniprotkb:YLPM1(gene name)|psi-mi:YLPM1(display_short)|uniprotkb:C14orf170(gene name synonym)|uniprotkb:ZAP3(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:1247"(microscale thermophoresis)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177713|imex:IM-25122-10|dip:DIP-200084E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119596(gene)|ensembl:ENST00000325680(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0032204"(regulation of telomere maintenance)|interpro:IPR026314|interpro:IPR027417|refseq:NP_062535.2|ensembl:ENSP00000324463|dip:DIP-53676N	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2018/04/06	rogid:3w+7odPC5D2UQYimwmCgTBbvWR49606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:5q2xTto0WHVQyIxNGgEbMUD9sbQ	false	sufficient binding region:73-95	sufficient binding region:729-799	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75044	uniprotkb:O75044	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177736|imex:IM-25122-11|dip:DIP-200080E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2018/01/16	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:+D5XqiTE4qYSfwJil/aFO34x8DY	false	sufficient binding region:729-815	sufficient binding region:729-815	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98171-1	uniprotkb:P98171-1	intact:EBI-16177615|ensembl:ENSP00000203786	intact:EBI-16177615|ensembl:ENSP00000203786	psi-mi:p98171-1(display_long)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)	psi-mi:p98171-1(display_long)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177626|imex:IM-25122-5|dip:DIP-200081E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2796462(isoform-parent)|ensembl:ENSG00000089820(gene)|ensembl:ENST00000350060(transcript)	intact:EBI-2796462(isoform-parent)|ensembl:ENSG00000089820(gene)|ensembl:ENST00000350060(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	rigid:4ApRSKMe2c1OmdJ8Wo/tnCG1ToU	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6N7	uniprotkb:O75044	intact:EBI-399762|uniprotkb:Q7Z300|uniprotkb:Q9BUS7|uniprotkb:D3DU36|uniprotkb:B2RXI1|uniprotkb:E9PD49|uniprotkb:Q1RMC7|ensembl:ENSP00000420321	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:robo1_human(display_long)|uniprotkb:ROBO1(gene name)|psi-mi:ROBO1(display_short)|uniprotkb:DUTT1(gene name synonym)|uniprotkb:H-Robo-1(gene name synonym)|uniprotkb:Deleted in U twenty twenty(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:1247"(microscale thermophoresis)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177594|imex:IM-25122-4|dip:DIP-200082E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139317.1|refseq:NP_002932.1|refseq:NP_598334.2|ensembl:ENSP00000420321|ensembl:ENST00000467549|ensembl:ENSP00000417992|ensembl:ENST00000495273|ensembl:ENSP00000420637|refseq:XP_006713340.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032986|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2EO9|rcsb pdb:2V9Q|rcsb pdb:2V9R|rcsb pdb:2V9T|rcsb pdb:3WIH|rcsb pdb:4HLJ|rcsb pdb:5O5G|rcsb pdb:5O5I|rcsb pdb:5OPE|rcsb pdb:6A77|rcsb pdb:6A78|ensembl:ENSG00000169855(gene)|ensembl:ENST00000464233(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009986"(cell surface)|refseq:XP_016862472.1|dip:DIP-33034N|rcsb pdb:6A79|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-8985801|reactome:R-HSA-9010553	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2018/01/16	rogid:LLHEVlylzhWB/zr77pQrNizgVsg9606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:w06Av31/ToZg5nQ27R1hAEGeEz0	false	sufficient binding region:1172-1198	sufficient binding region:1-799	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98171-1	uniprotkb:P98171-1	intact:EBI-16177615|ensembl:ENSP00000203786	intact:EBI-16177615|ensembl:ENSP00000203786	psi-mi:p98171-1(display_long)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)	psi-mi:p98171-1(display_long)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177642|imex:IM-25122-6|dip:DIP-200081E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2796462(isoform-parent)|ensembl:ENSG00000089820(gene)|ensembl:ENST00000350060(transcript)	intact:EBI-2796462(isoform-parent)|ensembl:ENSG00000089820(gene)|ensembl:ENST00000350060(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	rigid:4ApRSKMe2c1OmdJ8Wo/tnCG1ToU	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6N7	uniprotkb:O75044	intact:EBI-399762|uniprotkb:Q7Z300|uniprotkb:Q9BUS7|uniprotkb:D3DU36|uniprotkb:B2RXI1|uniprotkb:E9PD49|uniprotkb:Q1RMC7|ensembl:ENSP00000420321	intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3	psi-mi:robo1_human(display_long)|uniprotkb:ROBO1(gene name)|psi-mi:ROBO1(display_short)|uniprotkb:DUTT1(gene name synonym)|uniprotkb:H-Robo-1(gene name synonym)|uniprotkb:Deleted in U twenty twenty(gene name synonym)	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:"MI:1247"(microscale thermophoresis)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177754|imex:IM-25122-12|dip:DIP-200082E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139317.1|refseq:NP_002932.1|refseq:NP_598334.2|ensembl:ENSP00000420321|ensembl:ENST00000467549|ensembl:ENSP00000417992|ensembl:ENST00000495273|ensembl:ENSP00000420637|refseq:XP_006713340.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032986|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2EO9|rcsb pdb:2V9Q|rcsb pdb:2V9R|rcsb pdb:2V9T|rcsb pdb:3WIH|rcsb pdb:4HLJ|rcsb pdb:5O5G|rcsb pdb:5O5I|rcsb pdb:5OPE|rcsb pdb:6A77|rcsb pdb:6A78|ensembl:ENSG00000169855(gene)|ensembl:ENST00000464233(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009986"(cell surface)|refseq:XP_016862472.1|dip:DIP-33034N|rcsb pdb:6A79|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-8985801|reactome:R-HSA-9010553	refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2018/01/16	rogid:LLHEVlylzhWB/zr77pQrNizgVsg9606	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rigid:w06Av31/ToZg5nQ27R1hAEGeEz0	false	sufficient binding region:1472-1495	sufficient binding region:729-799	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98171-1	uniprotkb:Q9Y6N7	intact:EBI-16177615|ensembl:ENSP00000203786	intact:EBI-399762|uniprotkb:Q7Z300|uniprotkb:Q9BUS7|uniprotkb:D3DU36|uniprotkb:B2RXI1|uniprotkb:E9PD49|uniprotkb:Q1RMC7|ensembl:ENSP00000420321	psi-mi:p98171-1(display_long)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)	psi-mi:robo1_human(display_long)|uniprotkb:ROBO1(gene name)|psi-mi:ROBO1(display_short)|uniprotkb:DUTT1(gene name synonym)|uniprotkb:H-Robo-1(gene name synonym)|uniprotkb:Deleted in U twenty twenty(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Guez-Haddad et al. (2015)	pubmed:26365803|doi:10.1016/j.str.2015.08.009|imex:IM-25122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16177775|imex:IM-25122-13|dip:DIP-200085E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2796462(isoform-parent)|ensembl:ENSG00000089820(gene)|ensembl:ENST00000350060(transcript)	refseq:NP_001139317.1|refseq:NP_002932.1|refseq:NP_598334.2|ensembl:ENSP00000420321|ensembl:ENST00000467549|ensembl:ENSP00000417992|ensembl:ENST00000495273|ensembl:ENSP00000420637|refseq:XP_006713340.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032986|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2EO9|rcsb pdb:2V9Q|rcsb pdb:2V9R|rcsb pdb:2V9T|rcsb pdb:3WIH|rcsb pdb:4HLJ|rcsb pdb:5O5G|rcsb pdb:5O5I|rcsb pdb:5OPE|rcsb pdb:6A77|rcsb pdb:6A78|ensembl:ENSG00000169855(gene)|ensembl:ENST00000464233(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009986"(cell surface)|refseq:XP_016862472.1|dip:DIP-33034N|rcsb pdb:6A79|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-8985801|reactome:R-HSA-9010553	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	rogid:LLHEVlylzhWB/zr77pQrNizgVsg9606	rigid:u6kqh2Jf56Xkw1X4F+wvNoTMntw	false	-	sufficient binding region:1472-1495	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)