#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P37366	uniprotkb:P06242	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-9691|ensemblfungi:YDL108W|uniprotkb:D6VRP2	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:kin28_yeast(display_long)|uniprotkb:D2330(orf name)|uniprotkb:YDL108W(locus name)|uniprotkb:KIN28(gene name)|psi-mi:KIN28(display_short)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_010175.1|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|reactome:R-SCE-674695|go:"GO:0006995"(cellular response to nitrogen starvation)|reactome:R-SCE-6781823|go:"GO:0007049"(cell cycle)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1900018"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex)|go:"GO:1901921"(phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:1903654"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter)|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YDL108W(gene)|ensemblfungi:YDL108W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|sgd:S000002266|dip:DIP-2259N|mint:P06242	-	crc64:FE06E78FC38A8433	crc64:763A5720A1D9ACF3	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:2IOkuL0Hjco0/4jsi+kA39s5EBI559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:44-44|cross linker:32-32|cross linker:303-303|cross linker:303-303|cross linker:303-303|cross linker:240-240	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:Q00578	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578	-	crc64:FE06E78FC38A8433	crc64:FA4013E8156FE1C5	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:734-734|cross linker:357-357|cross linker:721-721|cross linker:228-228|cross linker:214-214|cross linker:357-357|cross linker:279-279|cross linker:228-228|cross linker:523-523|cross linker:64-64|cross linker:228-228|cross linker:12-12|cross linker:372-372	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:P06839	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-14762|ensemblfungi:YER171W|uniprotkb:D3DM79	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:rad3_yeast(display_long)|uniprotkb:RAD3(gene name)|psi-mi:RAD3(display_short)|uniprotkb:REM1(gene name synonym)|uniprotkb:DNA repair helicase RAD3(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit RAD3(gene name synonym)|uniprotkb:YER171W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	sgd:S000000973|ensemblfungi:YER171W(gene)|refseq:NP_011098.3|ensemblfungi:YER171W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009411"(response to UV)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|interpro:IPR042493|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|go:"GO:0000019"(regulation of mitotic recombination)|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|reactome:R-SCE-113418|reactome:R-SCE-5696395|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-2425N|mint:P06839	-	crc64:FE06E78FC38A8433	crc64:978BCA01751949B4	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:LNq4nTBI7aG+e2N6xMcc9OgQMUo559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	calmodulin binding peptide plus protein a tag:?-?|cross linker:476-476|cross linker:752-752|cross linker:125-125|cross linker:125-125|cross linker:2-2|cross linker:588-588|cross linker:364-364|cross linker:276-276|cross linker:2-2|cross linker:490-490|cross linker:731-731|cross linker:731-731|cross linker:499-499|cross linker:689-689|cross linker:588-588|cross linker:588-588|cross linker:588-588|cross linker:95-95|cross linker:95-95|cross linker:357-357|cross linker:125-125|cross linker:30-30|cross linker:499-499|cross linker:490-490|cross linker:499-499|cross linker:112-112|cross linker:125-125|cross linker:125-125|cross linker:125-125|cross linker:636-636	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:Q04673	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-18198|uniprotkb:E9P8Y6|uniprotkb:D6VY07|ensemblfungi:YLR005W	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:ssl1_yeast(display_long)|uniprotkb:SSL1(gene name)|psi-mi:SSL1(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit SSL1(gene name synonym)|uniprotkb:Suppressor of stem-loop protein 1(gene name synonym)|uniprotkb:YLR005W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_013105.1|sgd:S000003995|ensemblfungi:YLR005W(gene)|ensemblfungi:YLR005W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|rcsb pdb:4WFQ|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|interpro:IPR007198(Ssl1-like)|dip:DIP-2435N|mint:Q04673	-	crc64:FE06E78FC38A8433	crc64:57ADCB630B790B4F	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:NHwOfK411BNm3qDMqpfaQ7rbmRc559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:201-201|cross linker:201-201|cross linker:201-201|cross linker:397-397|cross linker:197-197|cross linker:52-52|cross linker:52-52|cross linker:52-52|cross linker:52-52|cross linker:112-112|cross linker:113-113|cross linker:52-52|cross linker:52-52|cross linker:397-397|cross linker:397-397|cross linker:397-397|cross linker:414-414|cross linker:321-321|cross linker:52-52|cross linker:197-197|cross linker:197-197|cross linker:88-88|cross linker:315-315|cross linker:52-52|cross linker:414-414|cross linker:201-201|cross linker:205-205|cross linker:112-112|cross linker:201-201|cross linker:201-201|cross linker:387-387|cross linker:113-113|cross linker:113-113|cross linker:205-205|cross linker:205-205|cross linker:457-457|cross linker:201-201|cross linker:52-52|cross linker:52-52	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:P32776	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	-	crc64:FE06E78FC38A8433	crc64:DAE369FE90A224F8	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:238-238|cross linker:483-483|cross linker:444-444|cross linker:401-401|cross linker:390-390|cross linker:335-335|cross linker:420-420|cross linker:101-101|cross linker:438-438|cross linker:238-238|cross linker:444-444|cross linker:120-120|cross linker:120-120|cross linker:458-458|cross linker:83-83|cross linker:451-451|cross linker:291-291|cross linker:291-291|cross linker:101-101|cross linker:120-120|cross linker:335-335|cross linker:73-73|cross linker:376-376|cross linker:120-120|cross linker:438-438|cross linker:120-120|cross linker:101-101|cross linker:438-438|cross linker:444-444|cross linker:246-246|cross linker:255-255|cross linker:438-438	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:Q02939	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-2345544|uniprotkb:D6W3P5|uniprotkb:P87331|ensemblfungi:YPL122C	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:tfb2_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B subunit 2(gene name synonym)|uniprotkb:YPL122C(locus name)|uniprotkb:TFB2(gene name)|psi-mi:TFB2(display_short)|uniprotkb:RNA polymerase II transcription factor B p52 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 52 kDa subunit(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_015203.1|sgd:S000006043|dip:DIP-5783N|mint:Q02939|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YPL122C(gene)|ensemblfungi:YPL122C_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73	-	crc64:FE06E78FC38A8433	crc64:9E440B566396A95A	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:TJC5kOBM7mOJLttEEiSqXvlVyXc559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:418-418|cross linker:427-427|cross linker:415-415|cross linker:313-313|cross linker:415-415|cross linker:415-415|cross linker:313-313|cross linker:419-419|cross linker:238-238|cross linker:238-238|cross linker:427-427|cross linker:427-427|cross linker:427-427|cross linker:427-427|cross linker:238-238|cross linker:238-238|cross linker:506-506|cross linker:495-495	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:Q03290	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-31406|uniprotkb:P89104|uniprotkb:D6VT84|ensemblfungi:YDR460W	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:tfb3_yeast(display_long)|uniprotkb:YDR460W(locus name)|uniprotkb:RNA polymerase II transcription factor B 38 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B p38 subunit(gene name synonym)|uniprotkb:TFB3(gene name)|psi-mi:TFB3(display_short)|uniprotkb:RIG2(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_010748.3|sgd:S000002868|dip:DIP-2398N|mint:Q03290|ensemblfungi:YDR460W(gene)|ensemblfungi:YDR460W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|interpro:IPR017907|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:6XI8|rcsb pdb:7KUE|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:FE06E78FC38A8433	crc64:528D61CF25ADFAF4	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:7zWyqSuWUYzGbjW/UzhOSXQ2FZs559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:235-235|cross linker:235-235|cross linker:10-10|cross linker:17-17|cross linker:235-235|cross linker:235-235|cross linker:1-1|cross linker:163-163|cross linker:226-226|cross linker:192-192|cross linker:219-219|cross linker:171-171|cross linker:1-1|cross linker:10-10|cross linker:1-1|cross linker:235-235|cross linker:235-235|cross linker:235-235|cross linker:1-1|cross linker:213-213|cross linker:235-235|cross linker:226-226|cross linker:171-171|cross linker:235-235|cross linker:226-226|cross linker:289-289	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:Q12004	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:FE06E78FC38A8433	crc64:B5C0CA95858453E0	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:16-16|cross linker:102-102|cross linker:95-95|cross linker:323-323|cross linker:108-108|cross linker:95-95|cross linker:323-323|cross linker:102-102|cross linker:173-173|cross linker:207-207|cross linker:323-323|cross linker:319-319|cross linker:173-173|cross linker:102-102|cross linker:173-173|cross linker:108-108|cross linker:187-187|cross linker:323-323|cross linker:323-323|cross linker:187-187|cross linker:323-323|cross linker:187-187|cross linker:102-102|cross linker:108-108|cross linker:207-207	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:Q3E7C1	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-2095127|uniprotkb:D6VS66|ensemblfungi:YDR079C-A	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:tfb5_yeast(display_long)|uniprotkb:TFB5(gene name)|psi-mi:TFB5(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 5(gene name synonym)|uniprotkb:YDR079C-A(locus name)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	sgd:S000007603|refseq:NP_076886.3|dip:DIP-48375N|mint:Q3E7C1|ensemblfungi:YDR079C-A(gene)|ensemblfungi:YDR079C-A_mRNA(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006294"(nucleotide-excision repair, preincision complex assembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR009400(Nucleotide excision repair, TFIIH, subunit TTDA)|interpro:IPR035935|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:FE06E78FC38A8433	crc64:9198E5CCFF304239	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:rLeTLiyG9AKYa+/o8zZ6lPYzYhc559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:6-6|cross linker:60-60|cross linker:6-6|cross linker:6-6|cross linker:6-6	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P37366	uniprotkb:Q08816	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	intact:EBI-35196|uniprotkb:D6W347|ensemblfungi:YOR352W	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:yo352_yeast(display_long)|uniprotkb:YOR352W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13950748|imex:IM-25757-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_014997.1|sgd:S000005879|mint:Q08816|dip:DIP-5639N|ensemblfungi:YOR352W(gene)|ensemblfungi:YOR352W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR031349	-	crc64:FE06E78FC38A8433	-	figure legend:Supp. Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rogid:fglO8qXipkj5rQvQlCxLzUi5u0A559292	rigid:m23kxk7LL5VxmaKf9LnVRZSJzQQ	false	cross linker:196-196|cross linker:247-247|cross linker:29-29|cross linker:24-24	cross linker:289-289|cross linker:162-162	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:P50613	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-1245958|uniprotkb:Q9BS60|uniprotkb:Q9UE19|ensembl:ENSP00000256443|ensembl:ENSP00000479116	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:cdk7_human(display_long)|uniprotkb:CDK7(gene name)|psi-mi:CDK7(display_short)|uniprotkb:MO15(gene name synonym)|uniprotkb:CAK(gene name synonym)|uniprotkb:CAK1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex kinase subunit(gene name synonym)|uniprotkb:39 kDa protein kinase(gene name synonym)|uniprotkb:CDKN7(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:Cell division protein kinase 7(gene name synonym)|uniprotkb:CDK-activating kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 1(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	refseq:NP_001790.1|refseq:NP_001310998.1|refseq:NP_001310999.1|refseq:NP_001311000.1|refseq:NP_001311006.1|dip:DIP-5995N|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSG00000134058(gene)|ensembl:ENSG00000277273(gene)|ensembl:ENST00000256443(transcript)|ensembl:ENST00000615305(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|rcsb pdb:1LG3|rcsb pdb:1PA8|rcsb pdb:1UA2|rcsb pdb:2HIC|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:pA9dLwvlBxPUAXW3bgv5M00qezk9606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:52-52|cross linker:293-293	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:P18074	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-6380590|ensembl:ENSP00000375809|ensembl:ENSP00000507019|uniprotkb:Q2TB78|uniprotkb:Q2YDY2|uniprotkb:Q7KZU6|uniprotkb:Q8N721	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:ercc2_human(display_long)|uniprotkb:ERCC2(gene name)|psi-mi:ERCC2(display_short)|uniprotkb:XPD(gene name synonym)|uniprotkb:XPDC(gene name synonym)|uniprotkb:Basic transcription factor 2 80 kDa subunit(gene name synonym)|uniprotkb:CXPD(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-2(gene name synonym)|uniprotkb:DNA repair protein complementing XP-D cells(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 80 kDa subunit(gene name synonym)|uniprotkb:Xeroderma pigmentosum group D-complementing protein(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	ensembl:ENSG00000104884(gene)|ensembl:ENST00000391945(transcript)|ensembl:ENST00000682414(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021510"(spinal cord development)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0071817"(MMXD complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|go:"GO:0006915"(apoptotic process)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|mint:P18074|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:6TUN|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-2564830|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|dip:DIP-644N|refseq:NP_000391.1|refseq:NP_001124339.1	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:zZKINZxsFZY4rkmg9VNqc4rTTjQ9606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:603-603|cross linker:113-113|cross linker:603-603|cross linker:29-29|cross linker:101-101|cross linker:682-682|cross linker:682-682|cross linker:682-682|cross linker:682-682|cross linker:507-507|cross linker:96-96|cross linker:603-603|cross linker:113-113|cross linker:82-82|cross linker:113-113|cross linker:82-82|cross linker:603-603|cross linker:689-689|cross linker:634-634|cross linker:634-634	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:P19447	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-1183307|uniprotkb:Q53QM0|ensembl:ENSP00000285398	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:ercc3_human(display_long)|uniprotkb:ERCC3(gene name)|psi-mi:ERCC3(display_short)|uniprotkb:XPB(gene name synonym)|uniprotkb:XPBC(gene name synonym)|uniprotkb:Basic transcription factor 2 89 kDa subunit(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 89 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein complementing XP-B cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group B-complementing protein(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-3(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	refseq:NP_000113.1|ensembl:ENSG00000163161(gene)|ensembl:ENST00000285398(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|mint:P19447|rcsb pdb:4ERN|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-73863|dip:DIP-83N	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:KOM9+f636LHK8qfTFkLIm0X0VoY9606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:44-44|cross linker:171-171|cross linker:142-142|cross linker:526-526|cross linker:706-706|cross linker:526-526|cross linker:241-241|cross linker:257-257|cross linker:379-379|cross linker:222-222|cross linker:326-326|cross linker:171-171|cross linker:171-171|cross linker:549-549|cross linker:171-171|cross linker:217-217|cross linker:222-222|cross linker:257-257|cross linker:142-142|cross linker:142-142|cross linker:767-767|cross linker:526-526|cross linker:59-59|cross linker:476-476|cross linker:167-167	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:P51948	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-716139|uniprotkb:Q15817|uniprotkb:G3V1U8|uniprotkb:Q6ICQ7|ensembl:ENSP00000261245	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:mat1_human(display_long)|uniprotkb:RING finger protein MAT1(gene name synonym)|uniprotkb:Menage a trois(gene name synonym)|uniprotkb:CDK7/cyclin-H assembly factor(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Cyclin-G1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 66(gene name synonym)|uniprotkb:MNAT1(gene name)|psi-mi:MNAT1(display_short)|uniprotkb:CAP35(gene name synonym)|uniprotkb:MAT1(gene name synonym)|uniprotkb:RNF66(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	refseq:NP_001171434.1|refseq:NP_002422.1|interpro:IPR017907|rcsb pdb:1G25|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6TUN|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000261245(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007512"(adult heart development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0021591"(ventricular system development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070985"(transcription factor TFIIK complex)|ensembl:ENSG00000020426(gene)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-8939236|refseq:XP_005267744.1	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:5Y/RExMrWjtftdbXuadagc0b+Kc9606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:55-55|cross linker:121-121|cross linker:180-180|cross linker:202-202|cross linker:176-176|cross linker:167-167|cross linker:167-167|cross linker:167-167|cross linker:167-167|cross linker:167-167	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:P32780	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:161-161|cross linker:353-353|cross linker:293-293|cross linker:296-296|cross linker:378-378|cross linker:38-38|cross linker:38-38|cross linker:353-353|cross linker:38-38|cross linker:252-252|cross linker:161-161|cross linker:365-365|cross linker:353-353|cross linker:353-353|cross linker:350-350|cross linker:350-350|cross linker:275-275|cross linker:293-293	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:Q13888	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-1565170|uniprotkb:Q15570|uniprotkb:Q15571|uniprotkb:Q9BS41|ensembl:ENSP00000274400|ensembl:ENSP00000328901|ensembl:ENSP00000477954|ensembl:ENSP00000479262|ensembl:ENSP00000480548|ensembl:ENSP00000486014	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:tf2h2_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:GTF2H2(gene name)|psi-mi:GTF2H2(display_short)|uniprotkb:BTF2P44(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	refseq:NP_001506.1|refseq:XP_016864894.1|refseq:XP_016864895.1|refseq:XP_016864892.1|refseq:XP_016864893.1|dip:DIP-786N|ensembl:ENSG00000145736(gene)|ensembl:ENSG00000275045(gene)|ensembl:ENSG00000276910(gene)|ensembl:ENST00000274400(transcript)|ensembl:ENST00000330280(transcript)|ensembl:ENST00000612581(transcript)|ensembl:ENST00000617228(transcript)|ensembl:ENST00000619997(transcript)|ensembl:ENST00000628423(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|mint:Q13888|rcsb pdb:1Z60|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:U4tPk4UlGiQz+exwhYG9kg7xGAM9606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:116-116|cross linker:126-126|cross linker:40-40|cross linker:126-126|cross linker:126-126|cross linker:31-31|cross linker:126-126|cross linker:42-42|cross linker:229-229|cross linker:229-229|cross linker:23-23|cross linker:31-31|cross linker:23-23|cross linker:40-40|cross linker:268-268|cross linker:77-77	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:Q13889	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:149-149|cross linker:125-125|cross linker:125-125|cross linker:149-149|cross linker:152-152|cross linker:97-97|cross linker:149-149|cross linker:149-149|cross linker:149-149|cross linker:152-152	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:Q92759	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-6380495|ensembl:ENSP00000259895|ensembl:ENSP00000365493|ensembl:ENSP00000365504|ensembl:ENSP00000383300|ensembl:ENSP00000387980|ensembl:ENSP00000388227|ensembl:ENSP00000395497|ensembl:ENSP00000396251|ensembl:ENSP00000399554|ensembl:ENSP00000401105|ensembl:ENSP00000403156|ensembl:ENSP00000409483|uniprotkb:Q76KU4|uniprotkb:B4DTJ5	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:tf2h4_human(display_long)|uniprotkb:GTF2H4(gene name)|psi-mi:GTF2H4(display_short)|uniprotkb:Basic transcription factor 2 52 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 4(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p52 subunit(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|reactome:R-HSA-167158|rcsb pdb:7EGB|reactome:R-HSA-167160|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|reactome:R-HSA-167161|rcsb pdb:7NVR|rcsb pdb:7NVV|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|rcsb pdb:7NVW|reactome:R-HSA-73772|rcsb pdb:7NVX|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|rcsb pdb:7NVY|reactome:R-HSA-77075|rcsb pdb:7NVZ|ensembl:ENSG00000213780(gene)|ensembl:ENSG00000221974(gene)|ensembl:ENSG00000226384(gene)|ensembl:ENSG00000233149(gene)|ensembl:ENSG00000234370(gene)|ensembl:ENSG00000236895(gene)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|ensembl:ENST00000259895(transcript)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|mint:Q92759|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|ensembl:ENST00000376316(transcript)|ensembl:ENST00000376326(transcript)|rcsb pdb:5IY8|ensembl:ENST00000400450(transcript)|ensembl:ENST00000413314(transcript)|rcsb pdb:5IY9|ensembl:ENST00000416773(transcript)|ensembl:ENST00000423881(transcript)|ensembl:ENST00000434226(transcript)|ensembl:ENST00000435498(transcript)|ensembl:ENST00000438348(transcript)|ensembl:ENST00000440824(transcript)|ensembl:ENST00000456968(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|dip:DIP-48376N|refseq:NP_001508.1	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:vQJkQt6yfTyMyQ6oYP1HpNv7hlY9606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:438-438|cross linker:378-378|cross linker:378-378|cross linker:378-378|cross linker:140-140|cross linker:277-277|cross linker:53-53|cross linker:452-452|cross linker:77-77|biological feature:378-378|cross linker:378-378|cross linker:127-127|cross linker:378-378|cross linker:378-378|cross linker:77-77|cross linker:378-378|cross linker:438-438|cross linker:456-456	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51946	uniprotkb:Q6ZYL4	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	intact:EBI-6380438|ensembl:ENSP00000476100|uniprotkb:Q0P5V8	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:tf2h5_human(display_long)|uniprotkb:TFIIH subunit p8(gene name synonym)|uniprotkb:GTF2H5(gene name)|psi-mi:GTF2H5(display_short)|uniprotkb:C6orf175(gene name synonym)|uniprotkb:TTDA(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 5(gene name synonym)|uniprotkb:TFB5 ortholog(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex TTD-A subunit(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001142|imex:IM-25757-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	ensembl:ENSG00000272047(gene)|ensembl:ENST00000607778(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006294"(nucleotide-excision repair, preincision complex assembly)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR009400(Nucleotide excision repair, TFIIH, subunit TTDA)|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|interpro:IPR035935|mint:Q6ZYL4|rcsb pdb:1YDL|rcsb pdb:2JNJ|rcsb pdb:5IVW|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:7NVZ|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|rcsb pdb:6RO4|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|dip:DIP-29188N|refseq:NP_997001.1	-	-	-	figure legend:Supp Fig. 1, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/17	2017/05/18	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rogid:6qEk3oQgejWFca2xqWRScoFdxNM9606	rigid:vj2w/s8aWFvBVhHartwPVaEYwv8	false	cross linker:239-239|cross linker:293-293	cross linker:31-31|cross linker:6-6|cross linker:71-71|cross linker:6-6|cross linker:71-71|cross linker:71-71|cross linker:71-71|cross linker:71-71|cross linker:6-6	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32776	uniprotkb:Q12004	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030547|imex:IM-25757-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:DAE369FE90A224F8	crc64:B5C0CA95858453E0	figure legend:Fig. 5A, 5B, Supp Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rigid:+BhNTxcjHT8knysXhJKUJuwmIrw	false	sufficient binding region:135-297,368-642	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q03290	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-31406|uniprotkb:P89104|uniprotkb:D6VT84|ensemblfungi:YDR460W	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:tfb3_yeast(display_long)|uniprotkb:YDR460W(locus name)|uniprotkb:RNA polymerase II transcription factor B 38 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B p38 subunit(gene name synonym)|uniprotkb:TFB3(gene name)|psi-mi:TFB3(display_short)|uniprotkb:RIG2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030547|imex:IM-25757-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_010748.3|sgd:S000002868|dip:DIP-2398N|mint:Q03290|ensemblfungi:YDR460W(gene)|ensemblfungi:YDR460W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|interpro:IPR017907|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:6XI8|rcsb pdb:7KUE|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:DAE369FE90A224F8	crc64:528D61CF25ADFAF4	figure legend:Fig. 5A, 5B, Supp Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:7zWyqSuWUYzGbjW/UzhOSXQ2FZs559292	rigid:+BhNTxcjHT8knysXhJKUJuwmIrw	false	sufficient binding region:135-297,368-642	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q02939	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-2345544|uniprotkb:D6W3P5|uniprotkb:P87331|ensemblfungi:YPL122C	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:tfb2_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B subunit 2(gene name synonym)|uniprotkb:YPL122C(locus name)|uniprotkb:TFB2(gene name)|psi-mi:TFB2(display_short)|uniprotkb:RNA polymerase II transcription factor B p52 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 52 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030547|imex:IM-25757-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_015203.1|sgd:S000006043|dip:DIP-5783N|mint:Q02939|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YPL122C(gene)|ensemblfungi:YPL122C_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73	-	crc64:DAE369FE90A224F8	crc64:9E440B566396A95A	figure legend:Fig. 5A, 5B, Supp Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:TJC5kOBM7mOJLttEEiSqXvlVyXc559292	rigid:+BhNTxcjHT8knysXhJKUJuwmIrw	false	sufficient binding region:135-297,368-642	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q04673	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-18198|uniprotkb:E9P8Y6|uniprotkb:D6VY07|ensemblfungi:YLR005W	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:ssl1_yeast(display_long)|uniprotkb:SSL1(gene name)|psi-mi:SSL1(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit SSL1(gene name synonym)|uniprotkb:Suppressor of stem-loop protein 1(gene name synonym)|uniprotkb:YLR005W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030547|imex:IM-25757-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_013105.1|sgd:S000003995|ensemblfungi:YLR005W(gene)|ensemblfungi:YLR005W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|rcsb pdb:4WFQ|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|interpro:IPR007198(Ssl1-like)|dip:DIP-2435N|mint:Q04673	-	crc64:DAE369FE90A224F8	crc64:57ADCB630B790B4F	figure legend:Fig. 5A, 5B, Supp Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:NHwOfK411BNm3qDMqpfaQ7rbmRc559292	rigid:+BhNTxcjHT8knysXhJKUJuwmIrw	false	sufficient binding region:135-297,368-642	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:P06839	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-14762|ensemblfungi:YER171W|uniprotkb:D3DM79	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:rad3_yeast(display_long)|uniprotkb:RAD3(gene name)|psi-mi:RAD3(display_short)|uniprotkb:REM1(gene name synonym)|uniprotkb:DNA repair helicase RAD3(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit RAD3(gene name synonym)|uniprotkb:YER171W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030547|imex:IM-25757-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	sgd:S000000973|ensemblfungi:YER171W(gene)|refseq:NP_011098.3|ensemblfungi:YER171W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009411"(response to UV)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|interpro:IPR042493|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|go:"GO:0000019"(regulation of mitotic recombination)|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|reactome:R-SCE-113418|reactome:R-SCE-5696395|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-2425N|mint:P06839	-	crc64:DAE369FE90A224F8	crc64:978BCA01751949B4	figure legend:Fig. 5A, 5B, Supp Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:LNq4nTBI7aG+e2N6xMcc9OgQMUo559292	rigid:+BhNTxcjHT8knysXhJKUJuwmIrw	false	sufficient binding region:135-297,368-642	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q00578	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030547|imex:IM-25757-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578	-	crc64:DAE369FE90A224F8	crc64:FA4013E8156FE1C5	figure legend:Fig. 5A, 5B, Supp Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292	rigid:+BhNTxcjHT8knysXhJKUJuwmIrw	false	sufficient binding region:135-297,368-642	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:P06242	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-9691|ensemblfungi:YDL108W|uniprotkb:D6VRP2	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:kin28_yeast(display_long)|uniprotkb:D2330(orf name)|uniprotkb:YDL108W(locus name)|uniprotkb:KIN28(gene name)|psi-mi:KIN28(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030547|imex:IM-25757-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_010175.1|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|reactome:R-SCE-674695|go:"GO:0006995"(cellular response to nitrogen starvation)|reactome:R-SCE-6781823|go:"GO:0007049"(cell cycle)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1900018"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex)|go:"GO:1901921"(phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:1903654"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter)|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YDL108W(gene)|ensemblfungi:YDL108W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|sgd:S000002266|dip:DIP-2259N|mint:P06242	-	crc64:DAE369FE90A224F8	crc64:763A5720A1D9ACF3	figure legend:Fig. 5A, 5B, Supp Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:2IOkuL0Hjco0/4jsi+kA39s5EBI559292	rigid:+BhNTxcjHT8knysXhJKUJuwmIrw	false	sufficient binding region:135-297,368-642	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q12004	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030597|imex:IM-25757-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:DAE369FE90A224F8	crc64:B5C0CA95858453E0	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletions that remove the BSD1 or BSD2 domains (delta5–7, 173-288)  all showed significant reductions in association with Rad3, Tfb3, Ssl2 and Kin28."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rigid:60xOsg3q/Km1bkltMC9iHqPiT3I	false	sufficient binding region:289-642,135-173(IPR005607)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q02939	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-2345544|uniprotkb:D6W3P5|uniprotkb:P87331|ensemblfungi:YPL122C	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:tfb2_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B subunit 2(gene name synonym)|uniprotkb:YPL122C(locus name)|uniprotkb:TFB2(gene name)|psi-mi:TFB2(display_short)|uniprotkb:RNA polymerase II transcription factor B p52 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 52 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030597|imex:IM-25757-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_015203.1|sgd:S000006043|dip:DIP-5783N|mint:Q02939|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YPL122C(gene)|ensemblfungi:YPL122C_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73	-	crc64:DAE369FE90A224F8	crc64:9E440B566396A95A	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletions that remove the BSD1 or BSD2 domains (delta5–7, 173-288)  all showed significant reductions in association with Rad3, Tfb3, Ssl2 and Kin28."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:TJC5kOBM7mOJLttEEiSqXvlVyXc559292	rigid:60xOsg3q/Km1bkltMC9iHqPiT3I	false	sufficient binding region:289-642,135-173(IPR005607)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q04673	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-18198|uniprotkb:E9P8Y6|uniprotkb:D6VY07|ensemblfungi:YLR005W	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:ssl1_yeast(display_long)|uniprotkb:SSL1(gene name)|psi-mi:SSL1(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit SSL1(gene name synonym)|uniprotkb:Suppressor of stem-loop protein 1(gene name synonym)|uniprotkb:YLR005W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030597|imex:IM-25757-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_013105.1|sgd:S000003995|ensemblfungi:YLR005W(gene)|ensemblfungi:YLR005W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|rcsb pdb:4WFQ|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|interpro:IPR007198(Ssl1-like)|dip:DIP-2435N|mint:Q04673	-	crc64:DAE369FE90A224F8	crc64:57ADCB630B790B4F	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletions that remove the BSD1 or BSD2 domains (delta5–7, 173-288)  all showed significant reductions in association with Rad3, Tfb3, Ssl2 and Kin28."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:NHwOfK411BNm3qDMqpfaQ7rbmRc559292	rigid:60xOsg3q/Km1bkltMC9iHqPiT3I	false	sufficient binding region:289-642,135-173(IPR005607)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q04673	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-18198|uniprotkb:E9P8Y6|uniprotkb:D6VY07|ensemblfungi:YLR005W	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:ssl1_yeast(display_long)|uniprotkb:SSL1(gene name)|psi-mi:SSL1(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit SSL1(gene name synonym)|uniprotkb:Suppressor of stem-loop protein 1(gene name synonym)|uniprotkb:YLR005W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030632|imex:IM-25757-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_013105.1|sgd:S000003995|ensemblfungi:YLR005W(gene)|ensemblfungi:YLR005W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|rcsb pdb:4WFQ|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|interpro:IPR007198(Ssl1-like)|dip:DIP-2435N|mint:Q04673	-	crc64:DAE369FE90A224F8	crc64:57ADCB630B790B4F	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletions that remove the BSD1 or BSD2 domains (delta5–7, 368-491)  all showed significant reductions in association with Rad3, Tfb3, Ssl2 and Kin28;Delta 9,10 shows  an additional defect in association with Tfb2"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:NHwOfK411BNm3qDMqpfaQ7rbmRc559292	rigid:6VIscgZL8jonxEXDO7aFaS9l71c	false	sufficient binding region:492-642,135-368	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q12004	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030632|imex:IM-25757-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:DAE369FE90A224F8	crc64:B5C0CA95858453E0	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletions that remove the BSD1 or BSD2 domains (delta5–7, 368-491)  all showed significant reductions in association with Rad3, Tfb3, Ssl2 and Kin28;Delta 9,10 shows  an additional defect in association with Tfb2"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rigid:6VIscgZL8jonxEXDO7aFaS9l71c	false	sufficient binding region:492-642,135-368	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q03290	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-31406|uniprotkb:P89104|uniprotkb:D6VT84|ensemblfungi:YDR460W	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:tfb3_yeast(display_long)|uniprotkb:YDR460W(locus name)|uniprotkb:RNA polymerase II transcription factor B 38 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B p38 subunit(gene name synonym)|uniprotkb:TFB3(gene name)|psi-mi:TFB3(display_short)|uniprotkb:RIG2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030644|imex:IM-25757-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_010748.3|sgd:S000002868|dip:DIP-2398N|mint:Q03290|ensemblfungi:YDR460W(gene)|ensemblfungi:YDR460W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|interpro:IPR017907|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:6XI8|rcsb pdb:7KUE|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:DAE369FE90A224F8	crc64:528D61CF25ADFAF4	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletion of the Tfb1 3-helix bundle C-terminus (368-642) is defective in interactions with Tfb2, Ssl1, and Tfb4."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:7zWyqSuWUYzGbjW/UzhOSXQ2FZs559292	rigid:4UHc8uhGnhnpnr2ef8pL2+GtsV8	false	sufficient binding region:135-367	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:P06839	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-14762|ensemblfungi:YER171W|uniprotkb:D3DM79	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:rad3_yeast(display_long)|uniprotkb:RAD3(gene name)|psi-mi:RAD3(display_short)|uniprotkb:REM1(gene name synonym)|uniprotkb:DNA repair helicase RAD3(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit RAD3(gene name synonym)|uniprotkb:YER171W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030644|imex:IM-25757-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	sgd:S000000973|ensemblfungi:YER171W(gene)|refseq:NP_011098.3|ensemblfungi:YER171W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009411"(response to UV)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|interpro:IPR042493|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|go:"GO:0000019"(regulation of mitotic recombination)|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|reactome:R-SCE-113418|reactome:R-SCE-5696395|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-2425N|mint:P06839	-	crc64:DAE369FE90A224F8	crc64:978BCA01751949B4	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletion of the Tfb1 3-helix bundle C-terminus (368-642) is defective in interactions with Tfb2, Ssl1, and Tfb4."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:LNq4nTBI7aG+e2N6xMcc9OgQMUo559292	rigid:4UHc8uhGnhnpnr2ef8pL2+GtsV8	false	sufficient binding region:135-367	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:Q00578	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030644|imex:IM-25757-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578	-	crc64:DAE369FE90A224F8	crc64:FA4013E8156FE1C5	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletion of the Tfb1 3-helix bundle C-terminus (368-642) is defective in interactions with Tfb2, Ssl1, and Tfb4."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292	rigid:4UHc8uhGnhnpnr2ef8pL2+GtsV8	false	sufficient binding region:135-367	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32776	uniprotkb:P06242	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	intact:EBI-9691|ensemblfungi:YDL108W|uniprotkb:D6VRP2	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:kin28_yeast(display_long)|uniprotkb:D2330(orf name)|uniprotkb:YDL108W(locus name)|uniprotkb:KIN28(gene name)|psi-mi:KIN28(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030644|imex:IM-25757-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	refseq:NP_010175.1|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|reactome:R-SCE-674695|go:"GO:0006995"(cellular response to nitrogen starvation)|reactome:R-SCE-6781823|go:"GO:0007049"(cell cycle)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1900018"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex)|go:"GO:1901921"(phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:1903654"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter)|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YDL108W(gene)|ensemblfungi:YDL108W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|sgd:S000002266|dip:DIP-2259N|mint:P06242	-	crc64:DAE369FE90A224F8	crc64:763A5720A1D9ACF3	figure legend:Fig. 5A, 5B, Supp Fig. 7A|comment:"Deletion of the Tfb1 3-helix bundle C-terminus (368-642) is defective in interactions with Tfb2, Ssl1, and Tfb4."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/18	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rogid:2IOkuL0Hjco0/4jsi+kA39s5EBI559292	rigid:4UHc8uhGnhnpnr2ef8pL2+GtsV8	false	sufficient binding region:135-367	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32780	uniprotkb:P19447	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-1183307|uniprotkb:Q53QM0|ensembl:ENSP00000285398	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:ercc3_human(display_long)|uniprotkb:ERCC3(gene name)|psi-mi:ERCC3(display_short)|uniprotkb:XPB(gene name synonym)|uniprotkb:XPBC(gene name synonym)|uniprotkb:Basic transcription factor 2 89 kDa subunit(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 89 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein complementing XP-B cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group B-complementing protein(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030682|imex:IM-25757-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	refseq:NP_000113.1|ensembl:ENSG00000163161(gene)|ensembl:ENST00000285398(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|mint:P19447|rcsb pdb:4ERN|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-73863|dip:DIP-83N	-	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/03/17	2017/06/06	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:KOM9+f636LHK8qfTFkLIm0X0VoY9606	rigid:shTh2/rMtooTVs+PFB8xFAc4SMY	false	flag tag:?-?|necessary binding region:328-432(IPR014001)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32780	uniprotkb:P18074	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-6380590|ensembl:ENSP00000375809|ensembl:ENSP00000507019|uniprotkb:Q2TB78|uniprotkb:Q2YDY2|uniprotkb:Q7KZU6|uniprotkb:Q8N721	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:ercc2_human(display_long)|uniprotkb:ERCC2(gene name)|psi-mi:ERCC2(display_short)|uniprotkb:XPD(gene name synonym)|uniprotkb:XPDC(gene name synonym)|uniprotkb:Basic transcription factor 2 80 kDa subunit(gene name synonym)|uniprotkb:CXPD(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-2(gene name synonym)|uniprotkb:DNA repair protein complementing XP-D cells(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 80 kDa subunit(gene name synonym)|uniprotkb:Xeroderma pigmentosum group D-complementing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030682|imex:IM-25757-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	ensembl:ENSG00000104884(gene)|ensembl:ENST00000391945(transcript)|ensembl:ENST00000682414(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021510"(spinal cord development)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0071817"(MMXD complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|go:"GO:0006915"(apoptotic process)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|mint:P18074|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:6TUN|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-2564830|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|dip:DIP-644N|refseq:NP_000391.1|refseq:NP_001124339.1	-	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/03/17	2017/06/06	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:zZKINZxsFZY4rkmg9VNqc4rTTjQ9606	rigid:shTh2/rMtooTVs+PFB8xFAc4SMY	false	flag tag:?-?|necessary binding region:328-432(IPR014001)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12004	uniprotkb:Q3E7C1	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-2095127|uniprotkb:D6VS66|ensemblfungi:YDR079C-A	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:tfb5_yeast(display_long)|uniprotkb:TFB5(gene name)|psi-mi:TFB5(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 5(gene name synonym)|uniprotkb:YDR079C-A(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	sgd:S000007603|refseq:NP_076886.3|dip:DIP-48375N|mint:Q3E7C1|ensemblfungi:YDR079C-A(gene)|ensemblfungi:YDR079C-A_mRNA(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006294"(nucleotide-excision repair, preincision complex assembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR009400(Nucleotide excision repair, TFIIH, subunit TTDA)|interpro:IPR035935|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:B5C0CA95858453E0	crc64:9198E5CCFF304239	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:rLeTLiyG9AKYa+/o8zZ6lPYzYhc559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:Q03290	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-31406|uniprotkb:P89104|uniprotkb:D6VT84|ensemblfungi:YDR460W	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:tfb3_yeast(display_long)|uniprotkb:YDR460W(locus name)|uniprotkb:RNA polymerase II transcription factor B 38 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B p38 subunit(gene name synonym)|uniprotkb:TFB3(gene name)|psi-mi:TFB3(display_short)|uniprotkb:RIG2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_010748.3|sgd:S000002868|dip:DIP-2398N|mint:Q03290|ensemblfungi:YDR460W(gene)|ensemblfungi:YDR460W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|interpro:IPR017907|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:6XI8|rcsb pdb:7KUE|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:B5C0CA95858453E0	crc64:528D61CF25ADFAF4	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:7zWyqSuWUYzGbjW/UzhOSXQ2FZs559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:Q02939	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-2345544|uniprotkb:D6W3P5|uniprotkb:P87331|ensemblfungi:YPL122C	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:tfb2_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B subunit 2(gene name synonym)|uniprotkb:YPL122C(locus name)|uniprotkb:TFB2(gene name)|psi-mi:TFB2(display_short)|uniprotkb:RNA polymerase II transcription factor B p52 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 52 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_015203.1|sgd:S000006043|dip:DIP-5783N|mint:Q02939|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YPL122C(gene)|ensemblfungi:YPL122C_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73	-	crc64:B5C0CA95858453E0	crc64:9E440B566396A95A	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:TJC5kOBM7mOJLttEEiSqXvlVyXc559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:P32776	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	-	crc64:B5C0CA95858453E0	crc64:DAE369FE90A224F8	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:Q04673	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-18198|uniprotkb:E9P8Y6|uniprotkb:D6VY07|ensemblfungi:YLR005W	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:ssl1_yeast(display_long)|uniprotkb:SSL1(gene name)|psi-mi:SSL1(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit SSL1(gene name synonym)|uniprotkb:Suppressor of stem-loop protein 1(gene name synonym)|uniprotkb:YLR005W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_013105.1|sgd:S000003995|ensemblfungi:YLR005W(gene)|ensemblfungi:YLR005W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|rcsb pdb:4WFQ|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|interpro:IPR007198(Ssl1-like)|dip:DIP-2435N|mint:Q04673	-	crc64:B5C0CA95858453E0	crc64:57ADCB630B790B4F	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:NHwOfK411BNm3qDMqpfaQ7rbmRc559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:P06839	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-14762|ensemblfungi:YER171W|uniprotkb:D3DM79	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:rad3_yeast(display_long)|uniprotkb:RAD3(gene name)|psi-mi:RAD3(display_short)|uniprotkb:REM1(gene name synonym)|uniprotkb:DNA repair helicase RAD3(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit RAD3(gene name synonym)|uniprotkb:YER171W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	sgd:S000000973|ensemblfungi:YER171W(gene)|refseq:NP_011098.3|ensemblfungi:YER171W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009411"(response to UV)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|interpro:IPR042493|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|go:"GO:0000019"(regulation of mitotic recombination)|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|reactome:R-SCE-113418|reactome:R-SCE-5696395|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-2425N|mint:P06839	-	crc64:B5C0CA95858453E0	crc64:978BCA01751949B4	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:LNq4nTBI7aG+e2N6xMcc9OgQMUo559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:Q00578	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578	-	crc64:B5C0CA95858453E0	crc64:FA4013E8156FE1C5	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:P06242	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-9691|ensemblfungi:YDL108W|uniprotkb:D6VRP2	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:kin28_yeast(display_long)|uniprotkb:D2330(orf name)|uniprotkb:YDL108W(locus name)|uniprotkb:KIN28(gene name)|psi-mi:KIN28(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_010175.1|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|reactome:R-SCE-674695|go:"GO:0006995"(cellular response to nitrogen starvation)|reactome:R-SCE-6781823|go:"GO:0007049"(cell cycle)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1900018"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex)|go:"GO:1901921"(phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:1903654"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter)|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YDL108W(gene)|ensemblfungi:YDL108W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|sgd:S000002266|dip:DIP-2259N|mint:P06242	-	crc64:B5C0CA95858453E0	crc64:763A5720A1D9ACF3	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:2IOkuL0Hjco0/4jsi+kA39s5EBI559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:P37366	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030699|imex:IM-25757-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:B5C0CA95858453E0	crc64:FE06E78FC38A8433	figure legend:Supp Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/04/12	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rigid:MoyUipcFdosnJLzaIfF6oK5MuAA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:P06242	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-9691|ensemblfungi:YDL108W|uniprotkb:D6VRP2	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:kin28_yeast(display_long)|uniprotkb:D2330(orf name)|uniprotkb:YDL108W(locus name)|uniprotkb:KIN28(gene name)|psi-mi:KIN28(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030716|imex:IM-25757-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_010175.1|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|reactome:R-SCE-674695|go:"GO:0006995"(cellular response to nitrogen starvation)|reactome:R-SCE-6781823|go:"GO:0007049"(cell cycle)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1900018"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex)|go:"GO:1901921"(phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:1903654"(phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter)|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YDL108W(gene)|ensemblfungi:YDL108W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|sgd:S000002266|dip:DIP-2259N|mint:P06242	-	crc64:B5C0CA95858453E0	crc64:763A5720A1D9ACF3	figure legend:Supp Fig. 7B|comment:Interaction observed in TFB5 -/- cells. SSL2 levels are significantly lower in the absence of TFB5 compared to the other subunits|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/22	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:2IOkuL0Hjco0/4jsi+kA39s5EBI559292	rigid:bWNiAmwBts8wNZEN7ES2iWrPURA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:Q03290	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-31406|uniprotkb:P89104|uniprotkb:D6VT84|ensemblfungi:YDR460W	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:tfb3_yeast(display_long)|uniprotkb:YDR460W(locus name)|uniprotkb:RNA polymerase II transcription factor B 38 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B p38 subunit(gene name synonym)|uniprotkb:TFB3(gene name)|psi-mi:TFB3(display_short)|uniprotkb:RIG2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030716|imex:IM-25757-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_010748.3|sgd:S000002868|dip:DIP-2398N|mint:Q03290|ensemblfungi:YDR460W(gene)|ensemblfungi:YDR460W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|interpro:IPR017907|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:6XI8|rcsb pdb:7KUE|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:B5C0CA95858453E0	crc64:528D61CF25ADFAF4	figure legend:Supp Fig. 7B|comment:Interaction observed in TFB5 -/- cells. SSL2 levels are significantly lower in the absence of TFB5 compared to the other subunits|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/22	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:7zWyqSuWUYzGbjW/UzhOSXQ2FZs559292	rigid:bWNiAmwBts8wNZEN7ES2iWrPURA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:Q02939	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-2345544|uniprotkb:D6W3P5|uniprotkb:P87331|ensemblfungi:YPL122C	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:tfb2_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B subunit 2(gene name synonym)|uniprotkb:YPL122C(locus name)|uniprotkb:TFB2(gene name)|psi-mi:TFB2(display_short)|uniprotkb:RNA polymerase II transcription factor B p52 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 52 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030716|imex:IM-25757-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_015203.1|sgd:S000006043|dip:DIP-5783N|mint:Q02939|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YPL122C(gene)|ensemblfungi:YPL122C_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73	-	crc64:B5C0CA95858453E0	crc64:9E440B566396A95A	figure legend:Supp Fig. 7B|comment:Interaction observed in TFB5 -/- cells. SSL2 levels are significantly lower in the absence of TFB5 compared to the other subunits|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/22	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:TJC5kOBM7mOJLttEEiSqXvlVyXc559292	rigid:bWNiAmwBts8wNZEN7ES2iWrPURA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:P32776	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-19146|uniprotkb:E9P948|uniprotkb:D6VSU0|ensemblfungi:YDR311W	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:tfb1_yeast(display_long)|uniprotkb:TFB1(gene name)|psi-mi:TFB1(display_short)|uniprotkb:RNA polymerase II transcription factor B p73 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 73 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit 1(gene name synonym)|uniprotkb:D9740.3(orf name)|uniprotkb:YDR311W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030716|imex:IM-25757-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	sgd:S000002719|ensemblfungi:YDR311W(gene)|ensemblfungi:YDR311W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|rcsb pdb:1Y5O|rcsb pdb:2GS0|rcsb pdb:2K2U|rcsb pdb:2L2I|rcsb pdb:2LOX|rcsb pdb:2M14|rcsb pdb:2MKR|rcsb pdb:2N0Y|rcsb pdb:2N23|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5URN|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|refseq:NP_010597.3|dip:DIP-1702N|mint:P32776	-	crc64:B5C0CA95858453E0	crc64:DAE369FE90A224F8	figure legend:Supp Fig. 7B|comment:Interaction observed in TFB5 -/- cells. SSL2 levels are significantly lower in the absence of TFB5 compared to the other subunits|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/22	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:se+ssALbdhXBSmWq07fKDAaxEHk559292	rigid:bWNiAmwBts8wNZEN7ES2iWrPURA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:Q04673	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-18198|uniprotkb:E9P8Y6|uniprotkb:D6VY07|ensemblfungi:YLR005W	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:ssl1_yeast(display_long)|uniprotkb:SSL1(gene name)|psi-mi:SSL1(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit SSL1(gene name synonym)|uniprotkb:Suppressor of stem-loop protein 1(gene name synonym)|uniprotkb:YLR005W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030716|imex:IM-25757-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_013105.1|sgd:S000003995|ensemblfungi:YLR005W(gene)|ensemblfungi:YLR005W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|rcsb pdb:4WFQ|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|interpro:IPR007198(Ssl1-like)|dip:DIP-2435N|mint:Q04673	-	crc64:B5C0CA95858453E0	crc64:57ADCB630B790B4F	figure legend:Supp Fig. 7B|comment:Interaction observed in TFB5 -/- cells. SSL2 levels are significantly lower in the absence of TFB5 compared to the other subunits|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/22	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:NHwOfK411BNm3qDMqpfaQ7rbmRc559292	rigid:bWNiAmwBts8wNZEN7ES2iWrPURA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:P06839	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-14762|ensemblfungi:YER171W|uniprotkb:D3DM79	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:rad3_yeast(display_long)|uniprotkb:RAD3(gene name)|psi-mi:RAD3(display_short)|uniprotkb:REM1(gene name synonym)|uniprotkb:DNA repair helicase RAD3(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit RAD3(gene name synonym)|uniprotkb:YER171W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030716|imex:IM-25757-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	sgd:S000000973|ensemblfungi:YER171W(gene)|refseq:NP_011098.3|ensemblfungi:YER171W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009411"(response to UV)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|interpro:IPR042493|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|go:"GO:0000019"(regulation of mitotic recombination)|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|reactome:R-SCE-113418|reactome:R-SCE-5696395|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-2425N|mint:P06839	-	crc64:B5C0CA95858453E0	crc64:978BCA01751949B4	figure legend:Supp Fig. 7B|comment:Interaction observed in TFB5 -/- cells. SSL2 levels are significantly lower in the absence of TFB5 compared to the other subunits|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/22	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:LNq4nTBI7aG+e2N6xMcc9OgQMUo559292	rigid:bWNiAmwBts8wNZEN7ES2iWrPURA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:P37366	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-4385|uniprotkb:D6W435|ensemblfungi:YPR025C	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:ccl1_yeast(display_long)|uniprotkb:CCL1(gene name)|psi-mi:CCL1(display_short)|uniprotkb:YP9367.05C(orf name)|uniprotkb:YPR025C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030716|imex:IM-25757-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_015350.1|sgd:S000006229|dip:DIP-2258N|mint:P37366|ensemblfungi:YPR025C(gene)|ensemblfungi:YPR025C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905866"(positive regulation of Atg1/ULK1 kinase complex assembly)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:6XI8|rcsb pdb:7KUE|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	-	crc64:B5C0CA95858453E0	crc64:FE06E78FC38A8433	figure legend:Supp Fig. 7B|comment:Interaction observed in TFB5 -/- cells. SSL2 levels are significantly lower in the absence of TFB5 compared to the other subunits|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/22	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:M3zzwsc3jy0dsHkK++fIK3t4wt8559292	rigid:bWNiAmwBts8wNZEN7ES2iWrPURA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12004	uniprotkb:Q00578	intact:EBI-29826|uniprotkb:D6W462|ensemblfungi:YPR056W	intact:EBI-14683|uniprotkb:D6VVE4|ensemblfungi:YIL143C	psi-mi:tfb4_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B p34 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 34 kDa subunit(gene name synonym)|uniprotkb:TFB4(gene name)|psi-mi:TFB4(display_short)|uniprotkb:RNA polymerase II transcription factor B subunit 4(gene name synonym)|uniprotkb:YPR056W(locus name)	psi-mi:rad25_yeast(display_long)|uniprotkb:YIL143C(locus name)|uniprotkb:SSL2(gene name)|psi-mi:SSL2(display_short)|uniprotkb:RAD25(gene name synonym)|uniprotkb:UVS112(gene name synonym)|uniprotkb:LOM3(gene name synonym)|uniprotkb:Suppressor of stem-loop mutation 2(gene name synonym)|uniprotkb:DNA repair helicase RAD25(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B subunit SSL2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14030716|imex:IM-25757-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015381.1|sgd:S000006260|dip:DIP-5634N|mint:Q12004|ensemblfungi:YPR056W(gene)|ensemblfungi:YPR056W_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075	refseq:NP_012123.1|sgd:S000001405|ensemblfungi:YIL143C(gene)|ensemblfungi:YIL143C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001111"(promoter clearance from RNA polymerase II promoter)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0005634"(nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|dip:DIP-731N|mint:Q00578	-	crc64:B5C0CA95858453E0	crc64:FA4013E8156FE1C5	figure legend:Supp Fig. 7B|comment:Interaction observed in TFB5 -/- cells. SSL2 levels are significantly lower in the absence of TFB5 compared to the other subunits|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/03/17	2017/05/22	rogid:BtyAeA7MS/Si1Zcq9DlF7v3nxUw559292	rogid:YtV99gfzqhICf6nFYLAhh3Kg0C0559292	rigid:bWNiAmwBts8wNZEN7ES2iWrPURA	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32780	uniprotkb:Q6P1K8	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-8469755|uniprotkb:A6NED9|uniprotkb:A8K8J6|uniprotkb:B2RCU4|uniprotkb:B7ZW39|intact:MINT-4906733|ensembl:ENSP00000370105|ensembl:ENSP00000422907|ensembl:ENSP00000480471|ensembl:ENSP00000483148	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:t2h2l_human(display_long)|uniprotkb:GTF2H2C(gene name)|psi-mi:GTF2H2C(display_short)|uniprotkb:GTF2H2C_2(gene name)|psi-mi:GTF2H2C_2(display_short)|uniprotkb:GTF2H2D(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 2-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14064284|imex:IM-25757-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	refseq:NP_001035955.1|refseq:NP_001092198.1|refseq:XP_005248645.1|refseq:XP_005248647.1|refseq:XP_006714751.1|ensembl:ENSG00000183474(gene)|ensembl:ENSG00000274675(gene)|ensembl:ENST00000380729(transcript)|ensembl:ENST00000510979(transcript)|ensembl:ENST00000619699(transcript)|ensembl:ENST00000621406(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|mint:Q6P1K8	-	-	comment:mint|comment:homomint	figure legend:Supp Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/03/17	2017/06/06	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:T36j4FIYLk1oSgzWnshu2uW/UbI9606	rigid:+lVTQwMHDBbrmBAl7J2/XODxVTU	false	flag tag:?-?|sufficient binding region:432-548,1-327(IPR014001)	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32780	uniprotkb:Q92759	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-6380495|ensembl:ENSP00000259895|ensembl:ENSP00000365493|ensembl:ENSP00000365504|ensembl:ENSP00000383300|ensembl:ENSP00000387980|ensembl:ENSP00000388227|ensembl:ENSP00000395497|ensembl:ENSP00000396251|ensembl:ENSP00000399554|ensembl:ENSP00000401105|ensembl:ENSP00000403156|ensembl:ENSP00000409483|uniprotkb:Q76KU4|uniprotkb:B4DTJ5	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:tf2h4_human(display_long)|uniprotkb:GTF2H4(gene name)|psi-mi:GTF2H4(display_short)|uniprotkb:Basic transcription factor 2 52 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 4(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p52 subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14064284|imex:IM-25757-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|reactome:R-HSA-167158|rcsb pdb:7EGB|reactome:R-HSA-167160|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|reactome:R-HSA-167161|rcsb pdb:7NVR|rcsb pdb:7NVV|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|rcsb pdb:7NVW|reactome:R-HSA-73772|rcsb pdb:7NVX|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|rcsb pdb:7NVY|reactome:R-HSA-77075|rcsb pdb:7NVZ|ensembl:ENSG00000213780(gene)|ensembl:ENSG00000221974(gene)|ensembl:ENSG00000226384(gene)|ensembl:ENSG00000233149(gene)|ensembl:ENSG00000234370(gene)|ensembl:ENSG00000236895(gene)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|ensembl:ENST00000259895(transcript)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|mint:Q92759|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|ensembl:ENST00000376316(transcript)|ensembl:ENST00000376326(transcript)|rcsb pdb:5IY8|ensembl:ENST00000400450(transcript)|ensembl:ENST00000413314(transcript)|rcsb pdb:5IY9|ensembl:ENST00000416773(transcript)|ensembl:ENST00000423881(transcript)|ensembl:ENST00000434226(transcript)|ensembl:ENST00000435498(transcript)|ensembl:ENST00000438348(transcript)|ensembl:ENST00000440824(transcript)|ensembl:ENST00000456968(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|dip:DIP-48376N|refseq:NP_001508.1	-	-	-	figure legend:Supp Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/03/17	2017/06/06	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:vQJkQt6yfTyMyQ6oYP1HpNv7hlY9606	rigid:+lVTQwMHDBbrmBAl7J2/XODxVTU	false	flag tag:?-?|sufficient binding region:432-548,1-327(IPR014001)	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32780	uniprotkb:Q13889	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14064284|imex:IM-25757-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2	-	-	-	figure legend:Supp Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/03/17	2017/06/06	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606	rigid:+lVTQwMHDBbrmBAl7J2/XODxVTU	false	flag tag:?-?|sufficient binding region:432-548,1-327(IPR014001)	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32780	uniprotkb:P51948	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-716139|uniprotkb:Q15817|uniprotkb:G3V1U8|uniprotkb:Q6ICQ7|ensembl:ENSP00000261245	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:mat1_human(display_long)|uniprotkb:RING finger protein MAT1(gene name synonym)|uniprotkb:Menage a trois(gene name synonym)|uniprotkb:CDK7/cyclin-H assembly factor(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Cyclin-G1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 66(gene name synonym)|uniprotkb:MNAT1(gene name)|psi-mi:MNAT1(display_short)|uniprotkb:CAP35(gene name synonym)|uniprotkb:MAT1(gene name synonym)|uniprotkb:RNF66(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14064284|imex:IM-25757-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	refseq:NP_001171434.1|refseq:NP_002422.1|interpro:IPR017907|rcsb pdb:1G25|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6TUN|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000261245(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007512"(adult heart development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0021591"(ventricular system development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070985"(transcription factor TFIIK complex)|ensembl:ENSG00000020426(gene)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-8939236|refseq:XP_005267744.1	-	-	-	figure legend:Supp Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/03/17	2017/06/06	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:5Y/RExMrWjtftdbXuadagc0b+Kc9606	rigid:+lVTQwMHDBbrmBAl7J2/XODxVTU	false	flag tag:?-?|sufficient binding region:432-548,1-327(IPR014001)	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32780	uniprotkb:P51946	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14064284|imex:IM-25757-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N	-	-	-	figure legend:Supp Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/03/17	2017/06/06	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606	rigid:+lVTQwMHDBbrmBAl7J2/XODxVTU	false	flag tag:?-?|sufficient binding region:432-548,1-327(IPR014001)	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P32780	uniprotkb:P50613	intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852	intact:EBI-1245958|uniprotkb:Q9BS60|uniprotkb:Q9UE19|ensembl:ENSP00000256443|ensembl:ENSP00000479116	psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym)	psi-mi:cdk7_human(display_long)|uniprotkb:CDK7(gene name)|psi-mi:CDK7(display_short)|uniprotkb:MO15(gene name synonym)|uniprotkb:CAK(gene name synonym)|uniprotkb:CAK1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex kinase subunit(gene name synonym)|uniprotkb:39 kDa protein kinase(gene name synonym)|uniprotkb:CDKN7(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:Cell division protein kinase 7(gene name synonym)|uniprotkb:CDK-activating kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Luo et al. (2015)	imex:IM-25757|pubmed:26340423	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14064284|imex:IM-25757-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N	refseq:NP_001790.1|refseq:NP_001310998.1|refseq:NP_001310999.1|refseq:NP_001311000.1|refseq:NP_001311006.1|dip:DIP-5995N|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSG00000134058(gene)|ensembl:ENSG00000277273(gene)|ensembl:ENST00000256443(transcript)|ensembl:ENST00000615305(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|rcsb pdb:1LG3|rcsb pdb:1PA8|rcsb pdb:1UA2|rcsb pdb:2HIC|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823	-	-	-	figure legend:Supp Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/03/17	2017/06/06	rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606	rogid:pA9dLwvlBxPUAXW3bgv5M00qezk9606	rigid:+lVTQwMHDBbrmBAl7J2/XODxVTU	false	flag tag:?-?|sufficient binding region:432-548,1-327(IPR014001)	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)