#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6R5N8 uniprotkb:Q6R5N8 intact:EBI-16173901|ensembl:ENSMUSP00000043101|uniprotkb:Q148Y7|uniprotkb:Q3TDS2 intact:EBI-16173901|ensembl:ENSMUSP00000043101|uniprotkb:Q148Y7|uniprotkb:Q3TDS2 psi-mi:tlr13_mouse(display_long)|uniprotkb:Tlr13(gene name)|psi-mi:Tlr13(display_short) psi-mi:tlr13_mouse(display_long)|uniprotkb:Tlr13(gene name)|psi-mi:Tlr13(display_short) psi-mi:"MI:0071"(molecular sieving) Song et al. (2015) pubmed:26323037|doi:10.1038/nsmb.3080|imex:IM-25143 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16173933|imex:IM-25143-1|dip:DIP-200535E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033777(gene)|ensembl:ENSMUST00000040065(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0034178"(toll-like receptor 13 signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4Z0C|refseq:NP_991389.1|dip:DIP-61832N ensembl:ENSMUSG00000033777(gene)|ensembl:ENSMUST00000040065(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0034178"(toll-like receptor 13 signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4Z0C|refseq:NP_991389.1|dip:DIP-61832N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:1sA/xVmaCZGIeEnzioTKrEEGDbs10090 rogid:1sA/xVmaCZGIeEnzioTKrEEGDbs10090 rigid:WMfplmU0+68xbPV7vvLWlyIxdVI false sufficient binding region:1-785|mutation disrupting interaction strength:580-580,579-579|mutation disrupting interaction strength:601-601|mutation disrupting interaction strength:609-609|mutation disrupting interaction strength:651-651,649-649 sufficient binding region:1-785|mutation disrupting interaction strength:580-580,579-579|mutation disrupting interaction strength:601-601|mutation disrupting interaction strength:609-609|mutation disrupting interaction strength:651-651,649-649 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6R5N8 uniprotkb:Q6R5N8 intact:EBI-16173901|ensembl:ENSMUSP00000043101|uniprotkb:Q148Y7|uniprotkb:Q3TDS2 intact:EBI-16173901|ensembl:ENSMUSP00000043101|uniprotkb:Q148Y7|uniprotkb:Q3TDS2 psi-mi:tlr13_mouse(display_long)|uniprotkb:Tlr13(gene name)|psi-mi:Tlr13(display_short) psi-mi:tlr13_mouse(display_long)|uniprotkb:Tlr13(gene name)|psi-mi:Tlr13(display_short) psi-mi:"MI:0114"(x-ray crystallography) Song et al. (2015) pubmed:26323037|doi:10.1038/nsmb.3080|imex:IM-25143 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16173984|imex:IM-25143-3|dip:DIP-200535E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033777(gene)|ensembl:ENSMUST00000040065(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0034178"(toll-like receptor 13 signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4Z0C|refseq:NP_991389.1|dip:DIP-61832N ensembl:ENSMUSG00000033777(gene)|ensembl:ENSMUST00000040065(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0034178"(toll-like receptor 13 signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4Z0C|refseq:NP_991389.1|dip:DIP-61832N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:1sA/xVmaCZGIeEnzioTKrEEGDbs10090 rogid:1sA/xVmaCZGIeEnzioTKrEEGDbs10090 rigid:WMfplmU0+68xbPV7vvLWlyIxdVI false sufficient binding region:1-785 sufficient binding region:1-785 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6R5N8 uniprotkb:Q6R5N8 intact:EBI-16173901|ensembl:ENSMUSP00000043101|uniprotkb:Q148Y7|uniprotkb:Q3TDS2 intact:EBI-16173901|ensembl:ENSMUSP00000043101|uniprotkb:Q148Y7|uniprotkb:Q3TDS2 psi-mi:tlr13_mouse(display_long)|uniprotkb:Tlr13(gene name)|psi-mi:Tlr13(display_short) psi-mi:tlr13_mouse(display_long)|uniprotkb:Tlr13(gene name)|psi-mi:Tlr13(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Song et al. (2015) pubmed:26323037|doi:10.1038/nsmb.3080|imex:IM-25143 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16173965|imex:IM-25143-2|dip:DIP-200535E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033777(gene)|ensembl:ENSMUST00000040065(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0034178"(toll-like receptor 13 signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4Z0C|refseq:NP_991389.1|dip:DIP-61832N ensembl:ENSMUSG00000033777(gene)|ensembl:ENSMUST00000040065(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0034178"(toll-like receptor 13 signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4Z0C|refseq:NP_991389.1|dip:DIP-61832N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:1sA/xVmaCZGIeEnzioTKrEEGDbs10090 rogid:1sA/xVmaCZGIeEnzioTKrEEGDbs10090 rigid:WMfplmU0+68xbPV7vvLWlyIxdVI false sufficient binding region:1-785 sufficient binding region:1-785 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6R5N8 uniprotkb:Q6R5N8 intact:EBI-16173901|ensembl:ENSMUSP00000043101|uniprotkb:Q148Y7|uniprotkb:Q3TDS2 intact:EBI-16173901|ensembl:ENSMUSP00000043101|uniprotkb:Q148Y7|uniprotkb:Q3TDS2 psi-mi:tlr13_mouse(display_long)|uniprotkb:Tlr13(gene name)|psi-mi:Tlr13(display_short) psi-mi:tlr13_mouse(display_long)|uniprotkb:Tlr13(gene name)|psi-mi:Tlr13(display_short) psi-mi:"MI:0410"(3D electron microscopy) Song et al. (2015) pubmed:26323037|doi:10.1038/nsmb.3080|imex:IM-25143 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16174002|imex:IM-25143-4|dip:DIP-200535E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033777(gene)|ensembl:ENSMUST00000040065(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0034178"(toll-like receptor 13 signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4Z0C|refseq:NP_991389.1|dip:DIP-61832N ensembl:ENSMUSG00000033777(gene)|ensembl:ENSMUST00000040065(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0034178"(toll-like receptor 13 signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4Z0C|refseq:NP_991389.1|dip:DIP-61832N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:1sA/xVmaCZGIeEnzioTKrEEGDbs10090 rogid:1sA/xVmaCZGIeEnzioTKrEEGDbs10090 rigid:WMfplmU0+68xbPV7vvLWlyIxdVI false sufficient binding region:1-785 sufficient binding region:1-785 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)