#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O70174	uniprotkb:Q8BLC3	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	intact:EBI-14035010|uniprotkb:Q3V2X5|uniprotkb:Q3V447|uniprotkb:Q9JJ96|ensembl:ENSMUSP00000125149	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:lypd1_mouse(display_long)|uniprotkb:Lypd1(gene name)|psi-mi:Lypd1(display_short)|uniprotkb:Lypdc1(gene name synonym)|uniprotkb:MNCb-0671(orf name)|uniprotkb:Ly-6/neurotoxin-like protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14033945|imex:IM-25754-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	refseq:NP_001298018.1|refseq:NP_001298019.1|refseq:NP_659568.2|ensembl:ENSMUSG00000026344(gene)|ensembl:ENSMUST00000159417(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0016020"(membrane)|go:"GO:0030550"(acetylcholine receptor inhibitor activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0045202"(synapse)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|reactome:R-MMU-163125|dip:DIP-48729N	-	-	-	figure legend:2A and C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2017/04/27	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rogid:U+Tywv7RwD89XRg5886pn3Yqnbk10090	rigid:Iy1piqTlge2Jkm/CLehnH2rhYNg	false	enhanced green fluorescent protein tag:426-426	myc tag:115..115-115..115	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O70174	uniprotkb:Q9ERK7	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	intact:EBI-10769401|uniprotkb:Q8BGP7|ensembl:ENSMUSP00000029562	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:achb2_mouse(display_long)|uniprotkb:Chrnb2(gene name)|psi-mi:Chrnb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14033945|imex:IM-25754-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	refseq:NP_033732.2|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|ensembl:ENSMUSG00000027950(gene)|ensembl:ENSMUST00000029562(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021562"(vestibulocochlear nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021771"(lateral geniculate nucleus development)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042320"(regulation of circadian sleep/wake cycle, REM sleep)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060084"(synaptic transmission involved in micturition)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1905144"(response to acetylcholine)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR032932|interpro:IPR036719|interpro:IPR036734|dip:DIP-48730N	-	-	-	figure legend:2A and C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2017/04/27	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rogid:oeSo9N32iwfTXZjeikOyJsQgo0U10090	rigid:Iy1piqTlge2Jkm/CLehnH2rhYNg	false	enhanced green fluorescent protein tag:426-426	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O70174	uniprotkb:Q9WUC3	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	intact:EBI-14033963|ensembl:ENSMUSP00000023241|ensembl:ENSMUSP00000070646|ensembl:ENSMUSP00000121951|ensembl:ENSMUSP00000130781	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:ly6h_mouse(display_long)|uniprotkb:Ly6h(gene name)|psi-mi:Ly6h(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14033957|imex:IM-25754-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	refseq:NP_001129160.1|refseq:NP_001129161.1|refseq:NP_035967.1|refseq:XP_006520962.1|refseq:XP_006520963.1|refseq:XP_006520964.1|refseq:XP_011243908.1|ensembl:ENSMUSG00000022577(gene)|ensembl:ENSMUST00000023241(transcript)|ensembl:ENSMUST00000065417(transcript)|ensembl:ENSMUST00000126129(transcript)|ensembl:ENSMUST00000163116(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0030550"(acetylcholine receptor inhibitor activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0045202"(synapse)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|reactome:R-MMU-163125	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2017/04/24	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rogid:JmourccYCQhtfwq1pFRZ/aOopwc10090	rigid:a1FR7YPUb3dCXKb3C0LofFLiVi4	false	enhanced green fluorescent protein tag:426-426	myc tag:110..110-110..110	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O70174	uniprotkb:Q9ERK7	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	intact:EBI-10769401|uniprotkb:Q8BGP7|ensembl:ENSMUSP00000029562	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:achb2_mouse(display_long)|uniprotkb:Chrnb2(gene name)|psi-mi:Chrnb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14033957|imex:IM-25754-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	refseq:NP_033732.2|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|ensembl:ENSMUSG00000027950(gene)|ensembl:ENSMUST00000029562(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021562"(vestibulocochlear nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021771"(lateral geniculate nucleus development)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042320"(regulation of circadian sleep/wake cycle, REM sleep)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060084"(synaptic transmission involved in micturition)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1905144"(response to acetylcholine)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR032932|interpro:IPR036719|interpro:IPR036734|dip:DIP-48730N	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2017/04/24	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rogid:oeSo9N32iwfTXZjeikOyJsQgo0U10090	rigid:a1FR7YPUb3dCXKb3C0LofFLiVi4	false	enhanced green fluorescent protein tag:426-426	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O70174	uniprotkb:Q64253	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	intact:EBI-14033999|uniprotkb:Q99JA5|uniprotkb:Q61128|ensembl:ENSMUSP00000056703|ensembl:ENSMUSP00000132081|ensembl:ENSMUSP00000139471|ensembl:ENSMUSP00000139549|ensembl:ENSMUSP00000140145|ensembl:ENSMUSP00000140553|ensembl:ENSMUSP00000141059|ensembl:ENSMUSP00000141145	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:ly6e_mouse(display_long)|uniprotkb:Ly6e(gene name)|psi-mi:Ly6e(display_short)|uniprotkb:Ly67(gene name synonym)|uniprotkb:Sca-2(gene name synonym)|uniprotkb:Tsa-1(gene name synonym)|uniprotkb:Stem cell antigen 2(gene name synonym)|uniprotkb:Thymic shared antigen 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14033993|imex:IM-25754-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	refseq:NP_001157508.1|refseq:NP_001157509.1|refseq:NP_001157510.1|refseq:NP_001157511.1|refseq:NP_001157512.1|refseq:NP_032555.1|ensembl:ENSMUSG00000022587(gene)|ensembl:ENSMUST00000051698(transcript)|ensembl:ENSMUST00000169343(transcript)|ensembl:ENSMUST00000185861(transcript)|ensembl:ENSMUST00000187284(transcript)|ensembl:ENSMUST00000187606(transcript)|ensembl:ENSMUST00000188042(transcript)|ensembl:ENSMUST00000188866(transcript)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048242"(epinephrine secretion)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|reactome:R-MMU-163125|ensembl:ENSMUST00000191436(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005886"(plasma membrane)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030550"(acetylcholine receptor inhibitor activity)	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2020/12/11	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rogid:NyMQXe6XDRIOrqC90y+jD2/Cwps10090	rigid:MnJ8cZGZY8f85lYm/TkfOWCi4BM	false	enhanced green fluorescent protein tag:426-426	myc tag:108..108-108..108	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O70174	uniprotkb:Q9ERK7	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	intact:EBI-10769401|uniprotkb:Q8BGP7|ensembl:ENSMUSP00000029562	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:achb2_mouse(display_long)|uniprotkb:Chrnb2(gene name)|psi-mi:Chrnb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14033993|imex:IM-25754-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	refseq:NP_033732.2|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|ensembl:ENSMUSG00000027950(gene)|ensembl:ENSMUST00000029562(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021562"(vestibulocochlear nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021771"(lateral geniculate nucleus development)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042320"(regulation of circadian sleep/wake cycle, REM sleep)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060084"(synaptic transmission involved in micturition)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1905144"(response to acetylcholine)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR032932|interpro:IPR036719|interpro:IPR036734|dip:DIP-48730N	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2020/12/11	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rogid:oeSo9N32iwfTXZjeikOyJsQgo0U10090	rigid:MnJ8cZGZY8f85lYm/TkfOWCi4BM	false	enhanced green fluorescent protein tag:426-426	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O70174	uniprotkb:Q8K1T6	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	intact:EBI-14034034|ensembl:ENSMUSP00000133753|uniprotkb:Q9D7E5	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:ly66e_mouse(display_long)|uniprotkb:Ly6g6e(gene name)|psi-mi:Ly6g6e(display_short)|uniprotkb:Lymphocyte antigen 6 complex locus protein G6e(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14034028|imex:IM-25754-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	refseq:XP_006524949.1|refseq:XP_006524950.1|ensembl:ENSMUSG00000013766(gene)|ensembl:ENSMUST00000172959(transcript)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004675"(transmembrane receptor protein serine/threonine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0042995"(cell projection)|go:"GO:0045202"(synapse)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR039700|refseq:NP_081642.1	go:"GO:0005886"(plasma membrane)	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2017/04/24	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rogid:l8RbJS1Oa1P5D+aNtrXyndMeadU10090	rigid:/7LmS77KF2MiaaTzDbHamd1vKNM	false	ha tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O70174	uniprotkb:Q9ERK7	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	intact:EBI-10769401|uniprotkb:Q8BGP7|ensembl:ENSMUSP00000029562	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:achb2_mouse(display_long)|uniprotkb:Chrnb2(gene name)|psi-mi:Chrnb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14034028|imex:IM-25754-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	refseq:NP_033732.2|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|ensembl:ENSMUSG00000027950(gene)|ensembl:ENSMUST00000029562(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021562"(vestibulocochlear nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021771"(lateral geniculate nucleus development)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042320"(regulation of circadian sleep/wake cycle, REM sleep)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060084"(synaptic transmission involved in micturition)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1905144"(response to acetylcholine)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR032932|interpro:IPR036719|interpro:IPR036734|dip:DIP-48730N	go:"GO:0005886"(plasma membrane)	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2017/04/24	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rogid:oeSo9N32iwfTXZjeikOyJsQgo0U10090	rigid:/7LmS77KF2MiaaTzDbHamd1vKNM	false	ha tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8BLC3	uniprotkb:O70174	intact:EBI-14035010|uniprotkb:Q3V2X5|uniprotkb:Q3V447|uniprotkb:Q9JJ96|ensembl:ENSMUSP00000125149	intact:EBI-10916203|uniprotkb:Q8BHE9|uniprotkb:Q8VI10|uniprotkb:Q9ET51|ensembl:ENSMUSP00000066338	psi-mi:lypd1_mouse(display_long)|uniprotkb:Lypd1(gene name)|psi-mi:Lypd1(display_short)|uniprotkb:Lypdc1(gene name synonym)|uniprotkb:MNCb-0671(orf name)|uniprotkb:Ly-6/neurotoxin-like protein 2(gene name synonym)	psi-mi:acha4_mouse(display_long)|uniprotkb:Chrna4(gene name)|psi-mi:Chrna4(display_short)|uniprotkb:Acra4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2015)	imex:IM-25754|pubmed:26276394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-14034056|imex:IM-25754-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001298018.1|refseq:NP_001298019.1|refseq:NP_659568.2|ensembl:ENSMUSG00000026344(gene)|ensembl:ENSMUST00000159417(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0016020"(membrane)|go:"GO:0030550"(acetylcholine receptor inhibitor activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0045202"(synapse)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|reactome:R-MMU-163125|dip:DIP-48729N	refseq:NP_056545.3|ensembl:ENSMUSG00000027577(gene)|ensembl:ENSMUST00000067120(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005216"(ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035640"(exploration behavior)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|dip:DIP-48731N	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-tsa201)|taxid:9606(Homo sapiens subclone of human embryonic kidney 293 cell line that expresses simian virus 40 T antigen)	-	2017/04/24	2017/04/27	rogid:U+Tywv7RwD89XRg5886pn3Yqnbk10090	rogid:6NTz9jTbBTHlZzu03cK7SfcZLfU10090	rigid:fiLPWxGFdfncWqe4Yu/HuQHQfNY	false	myc tag:115..115-115..115	enhanced green fluorescent protein tag:426-426	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)