#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P24339	uniprotkb:P87169	intact:EBI-16168992|ensemblfungi:"SPAC25G10.07c.1:pep"	intact:EBI-16079828	psi-mi:cut7_schpo(display_long)|uniprotkb:cut7(gene name)|psi-mi:cut7(display_short)|uniprotkb:Cell untimely torn protein 7(gene name synonym)|uniprotkb:SPAC25G10.07c(orf name)	psi-mi:mad1_schpo(display_long)|uniprotkb:mad1(gene name)|psi-mi:mad1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:SPBC3D6.04c(orf name)	psi-mi:"MI:0018"(two hybrid)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169051|imex:IM-24755-2|dip:DIP-199637E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPAC25G10.07c(gene)|ensemblfungi:SPAC25G10.07c.1(transcript)|go:"GO:0000073"(initial mitotic spindle pole body separation)|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0140013"(meiotic nuclear division)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:5M5I|rcsb pdb:5M5L|rcsb pdb:5M5M|rcsb pdb:5M5N|rcsb pdb:5M5O|rcsb pdb:5MLV|rcsb pdb:6S8M|dip:DIP-61701N|reactome:R-SPO-983189|refseq:NP_594527.1	go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|interpro:IPR008672(Mitotic checkpoint)|dip:DIP-61700N|refseq:NP_595516.1	psi-mi:"MI:0465"(dip)	crc64:5669277875559D58	crc64:2D2A34114F108C3A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:p7I8omjbvceK2er8nQdFfdwAQe0284812	rogid:sy68scND+Ofd4jAkkyQRJJ6K530284812	rigid:g3hIKFwY+Ll9Vj2owaGy6oJ0jfw	false	sufficient binding region:475-1085	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P24339	uniprotkb:P24339	intact:EBI-16168992|ensemblfungi:"SPAC25G10.07c.1:pep"	intact:EBI-16168992|ensemblfungi:"SPAC25G10.07c.1:pep"	psi-mi:cut7_schpo(display_long)|uniprotkb:cut7(gene name)|psi-mi:cut7(display_short)|uniprotkb:Cell untimely torn protein 7(gene name synonym)|uniprotkb:SPAC25G10.07c(orf name)	psi-mi:cut7_schpo(display_long)|uniprotkb:cut7(gene name)|psi-mi:cut7(display_short)|uniprotkb:Cell untimely torn protein 7(gene name synonym)|uniprotkb:SPAC25G10.07c(orf name)	psi-mi:"MI:0030"(cross-linking study)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169031|imex:IM-24755-1|dip:DIP-199640E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPAC25G10.07c(gene)|ensemblfungi:SPAC25G10.07c.1(transcript)|go:"GO:0000073"(initial mitotic spindle pole body separation)|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0140013"(meiotic nuclear division)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:5M5I|rcsb pdb:5M5L|rcsb pdb:5M5M|rcsb pdb:5M5N|rcsb pdb:5M5O|rcsb pdb:5MLV|rcsb pdb:6S8M|dip:DIP-61701N|reactome:R-SPO-983189|refseq:NP_594527.1	ensemblfungi:SPAC25G10.07c(gene)|ensemblfungi:SPAC25G10.07c.1(transcript)|go:"GO:0000073"(initial mitotic spindle pole body separation)|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0140013"(meiotic nuclear division)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:5M5I|rcsb pdb:5M5L|rcsb pdb:5M5M|rcsb pdb:5M5N|rcsb pdb:5M5O|rcsb pdb:5MLV|rcsb pdb:6S8M|dip:DIP-61701N|reactome:R-SPO-983189|refseq:NP_594527.1	psi-mi:"MI:0465"(dip)	crc64:5669277875559D58	crc64:5669277875559D58	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:p7I8omjbvceK2er8nQdFfdwAQe0284812	rogid:p7I8omjbvceK2er8nQdFfdwAQe0284812	rigid:dL1xuH5BReII5Be1/rwKmO49UN8	false	his tag:n-n|sufficient binding region:1-850	his tag:n-n|sufficient binding region:1-850	-	0	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O14417	uniprotkb:P87169	intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep"	intact:EBI-16079828	psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name)	psi-mi:mad1_schpo(display_long)|uniprotkb:mad1(gene name)|psi-mi:mad1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:SPBC3D6.04c(orf name)	psi-mi:"MI:0018"(two hybrid)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169070|imex:IM-24755-3|dip:DIP-199638E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430	go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|interpro:IPR008672(Mitotic checkpoint)|dip:DIP-61700N|refseq:NP_595516.1	psi-mi:"MI:0465"(dip)	crc64:DC9D1D213450C925	crc64:2D2A34114F108C3A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812	rogid:sy68scND+Ofd4jAkkyQRJJ6K530284812	rigid:es9xPbH1UbJq750M1b8E3OmzCls	false	-	sufficient binding region:59-689|mutation disrupting interaction strength:526-526,525-525,524-524,523-523	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P24339	uniprotkb:P87169	intact:EBI-16168992|ensemblfungi:"SPAC25G10.07c.1:pep"	intact:EBI-16079828	psi-mi:cut7_schpo(display_long)|uniprotkb:cut7(gene name)|psi-mi:cut7(display_short)|uniprotkb:Cell untimely torn protein 7(gene name synonym)|uniprotkb:SPAC25G10.07c(orf name)	psi-mi:mad1_schpo(display_long)|uniprotkb:mad1(gene name)|psi-mi:mad1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:SPBC3D6.04c(orf name)	psi-mi:"MI:0096"(pull down)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169176|imex:IM-24755-7|dip:DIP-199637E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPAC25G10.07c(gene)|ensemblfungi:SPAC25G10.07c.1(transcript)|go:"GO:0000073"(initial mitotic spindle pole body separation)|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0140013"(meiotic nuclear division)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:5M5I|rcsb pdb:5M5L|rcsb pdb:5M5M|rcsb pdb:5M5N|rcsb pdb:5M5O|rcsb pdb:5MLV|rcsb pdb:6S8M|dip:DIP-61701N|reactome:R-SPO-983189|refseq:NP_594527.1	go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|interpro:IPR008672(Mitotic checkpoint)|dip:DIP-61700N|refseq:NP_595516.1	psi-mi:"MI:0465"(dip)	crc64:5669277875559D58	crc64:2D2A34114F108C3A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:p7I8omjbvceK2er8nQdFfdwAQe0284812	rogid:sy68scND+Ofd4jAkkyQRJJ6K530284812	rigid:g3hIKFwY+Ll9Vj2owaGy6oJ0jfw	false	his tag:n-n	necessary binding region:31-40|mutation disrupting interaction strength:38-38,37-37|glutathione s tranferase tag:n-n|mutation decreasing interaction strength:32-32,31-31,30-30,29-29,28-28	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y6D9	uniprotkb:Q02224	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169210|imex:IM-24755-8|dip:DIP-199641E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rigid:w9oLkL7yc8F08rWDeZsacvi+2OE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y6D9	uniprotkb:Q13257	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169210|imex:IM-24755-8|dip:DIP-199641E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606	rigid:w9oLkL7yc8F08rWDeZsacvi+2OE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O14417	uniprotkb:P87169	intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep"	intact:EBI-16079828	psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name)	psi-mi:mad1_schpo(display_long)|uniprotkb:mad1(gene name)|psi-mi:mad1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:SPBC3D6.04c(orf name)	psi-mi:"MI:0018"(two hybrid)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169159|imex:IM-24755-6|dip:DIP-199638E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430	go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|interpro:IPR008672(Mitotic checkpoint)|dip:DIP-61700N|refseq:NP_595516.1	psi-mi:"MI:0465"(dip)	crc64:DC9D1D213450C925	crc64:2D2A34114F108C3A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812	rogid:sy68scND+Ofd4jAkkyQRJJ6K530284812	rigid:es9xPbH1UbJq750M1b8E3OmzCls	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P87169	uniprotkb:P87169	intact:EBI-16079828	intact:EBI-16079828	psi-mi:mad1_schpo(display_long)|uniprotkb:mad1(gene name)|psi-mi:mad1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:SPBC3D6.04c(orf name)	psi-mi:mad1_schpo(display_long)|uniprotkb:mad1(gene name)|psi-mi:mad1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:SPBC3D6.04c(orf name)	psi-mi:"MI:0018"(two hybrid)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169228|imex:IM-24755-9|dip:DIP-199639E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|interpro:IPR008672(Mitotic checkpoint)|dip:DIP-61700N|refseq:NP_595516.1	go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|interpro:IPR008672(Mitotic checkpoint)|dip:DIP-61700N|refseq:NP_595516.1	psi-mi:"MI:0465"(dip)	crc64:2D2A34114F108C3A	crc64:2D2A34114F108C3A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:sy68scND+Ofd4jAkkyQRJJ6K530284812	rogid:sy68scND+Ofd4jAkkyQRJJ6K530284812	rigid:oUwMnuTeFPfKZVoizPRKQ1ov1TE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P24339	uniprotkb:P87169	intact:EBI-16168992|ensemblfungi:"SPAC25G10.07c.1:pep"	intact:EBI-16079828	psi-mi:cut7_schpo(display_long)|uniprotkb:cut7(gene name)|psi-mi:cut7(display_short)|uniprotkb:Cell untimely torn protein 7(gene name synonym)|uniprotkb:SPAC25G10.07c(orf name)	psi-mi:mad1_schpo(display_long)|uniprotkb:mad1(gene name)|psi-mi:mad1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:SPBC3D6.04c(orf name)	psi-mi:"MI:0018"(two hybrid)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169095|imex:IM-24755-4|dip:DIP-199637E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPAC25G10.07c(gene)|ensemblfungi:SPAC25G10.07c.1(transcript)|go:"GO:0000073"(initial mitotic spindle pole body separation)|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0140013"(meiotic nuclear division)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:5M5I|rcsb pdb:5M5L|rcsb pdb:5M5M|rcsb pdb:5M5N|rcsb pdb:5M5O|rcsb pdb:5MLV|rcsb pdb:6S8M|dip:DIP-61701N|reactome:R-SPO-983189|refseq:NP_594527.1	go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|interpro:IPR008672(Mitotic checkpoint)|dip:DIP-61700N|refseq:NP_595516.1	psi-mi:"MI:0465"(dip)	crc64:5669277875559D58	crc64:2D2A34114F108C3A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:p7I8omjbvceK2er8nQdFfdwAQe0284812	rogid:sy68scND+Ofd4jAkkyQRJJ6K530284812	rigid:g3hIKFwY+Ll9Vj2owaGy6oJ0jfw	false	sufficient binding region:475-1085	sufficient binding region:14-59|necessary binding region:31-40|mutation disrupting interaction strength:38-38,37-37|necessary binding region:23-30|mutation disrupting interaction strength:32-32,31-31,30-30,29-29,28-28	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02224	uniprotkb:Q9Y6D9	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0096"(pull down)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169131|imex:IM-24755-5|dip:DIP-199642E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2019/11/13	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rigid:ErcWvoq+/Ulyh802XcjR0O59eMU	false	sufficient binding region:1958-2663	glutathione s tranferase tag:n-n|mutation disrupting interaction strength:21-21,20-20,19-19,18-18,17-17	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q02224	uniprotkb:Q9Y6D9	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0096"(pull down)	Akera et al. (2015)	pubmed:26258632|doi:10.1038/ncb3219|imex:IM-24755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16169245|imex:IM-24755-10|dip:DIP-199642E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2019/11/13	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rigid:ErcWvoq+/Ulyh802XcjR0O59eMU	false	sufficient binding region:1958-2663|maltose binding protein tag:?-?	mutation decreasing interaction strength:21-21,20-20,19-19,18-18,17-17|ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)