#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53859 uniprotkb:P38801 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1909|uniprotkb:D3DL32|ensemblfungi:YHR081W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:lrp1_yeast(display_long)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:Like an rRNA processing protein 1(gene name synonym)|uniprotkb:rRNA processing protein 47(gene name synonym)|uniprotkb:RRP47(gene name synonym)|uniprotkb:YC1D(gene name synonym)|uniprotkb:Yeast C1D domain-containing protein(gene name synonym)|uniprotkb:YHR081W(locus name) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011949.1|sgd:S000001123|dip:DIP-4359N|mint:P38801|ensemblfungi:YHR081W(gene)|ensemblfungi:YHR081W_mRNA(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1901917"(regulation of exoribonuclease activity)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:27D00668C296CC9A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:cQaT2zPsTCZHkLjuYBNF012Ym38559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P48240 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1749|uniprotkb:D6VUT8|ensemblfungi:YGR158C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:mtr3_yeast(display_long)|uniprotkb:MTR3(gene name)|psi-mi:MTR3(display_short)|uniprotkb:YGR158C(locus name)|uniprotkb:G6676(orf name)|uniprotkb:mRNA transport regulator 3(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000003390|refseq:NP_011674.3|dip:DIP-931N|mint:P48240|ensemblfungi:YGR158C(gene)|ensemblfungi:YGR158C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:2FA07ABB4A1115E0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:t5M0E3avqoJ0dbM51kE3fZlz2pc559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q08285 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1831|ensemblfungi:YOL142W|uniprotkb:D6W1S7|uniprotkb:E9P8Z4 psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp40_yeast(display_long)|uniprotkb:RRP40(gene name)|psi-mi:RRP40(display_short)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:YOL142W(locus name) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_014499.2|sgd:S000005502|ensemblfungi:YOL142W(gene)|ensemblfungi:YOL142W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030145"(manganese ion binding)|dip:DIP-5330N|mint:Q08285|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|interpro:IPR041054|rcsb pdb:2JA9|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:62B3A30348BBAA7C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:3sdpWE2qP6cVgcD2b8VDWV0ox4g559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P46948 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:C80EFFB528A43044 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q12277 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1765|uniprotkb:D6VRN9|ensemblfungi:YDL111C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp42_yeast(display_long)|uniprotkb:RRP42(gene name)|psi-mi:RRP42(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:YDL111C(locus name) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_010172.1|sgd:S000002269|dip:DIP-1463N|mint:Q12277|ensemblfungi:YDL111C(gene)|ensemblfungi:YDL111C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:806C60979642C67E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:OVyAr6b3ECMjQj3nUsuxXZqxt1o559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P25359 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1773|uniprotkb:Q8NKJ5|ensemblfungi:YCR035C|uniprotkb:D6VR45 psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp43_yeast(display_long)|uniprotkb:RRP43(gene name)|psi-mi:RRP43(display_short)|uniprotkb:YCR035C(locus name)|uniprotkb:YCR35C(orf name)|uniprotkb:YCR522(orf name)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 ensemblfungi:YCR035C(gene)|ensemblfungi:YCR035C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|refseq:NP_009964.2|sgd:S000000631|dip:DIP-5485N|mint:P25359|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:8801837B8184134D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:htGDTlKKMq7OdwcfGUKgfWCjJ1k559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q08162 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1740|uniprotkb:D6W244|ensemblfungi:YOL021C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp44_yeast(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Chromosome disjunction protein 3(gene name synonym)|uniprotkb:RRP44(gene name synonym)|uniprotkb:O2197(orf name)|uniprotkb:YOL021C(locus name) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000005381|refseq:NP_014621.1|dip:DIP-2355N|mint:Q08162|ensemblfungi:YOL021C(gene)|ensemblfungi:YOL021C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR022967|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|rcsb pdb:2VNU|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:00DD31BD2D6904F4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:YpToZNRenOPYsPJdGKEWBLsc4zA559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q05636 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1810|uniprotkb:D6VSR0|ensemblfungi:YDR280W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp45_yeast(display_long)|uniprotkb:RRP45(gene name)|psi-mi:RRP45(display_short)|uniprotkb:YDR280W(locus name)|uniprotkb:D9954.1(orf name)|uniprotkb:Ribosomal RNA-processing protein 45(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_010566.1|sgd:S000002688|dip:DIP-2084N|mint:Q05636|ensemblfungi:YDR280W(gene)|ensemblfungi:YDR280W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:65C9DB5A63678F2D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:LCdt9Nm8j2AD6iecBI2CGCrhEhQ559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P53256 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1842|uniprotkb:Q6TQU1|uniprotkb:D6VUM7|ensemblfungi:YGR095C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp46_yeast(display_long)|uniprotkb:RRP46(gene name)|psi-mi:RRP46(display_short)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:YGR095C(locus name) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011609.2|sgd:S000003327|dip:DIP-6838N|mint:P53256|ensemblfungi:YGR095C(gene)|ensemblfungi:YGR095C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:F1307E0EE4FC3133 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:2ESxObCiXUjTEvlB5ow7eCgivz0559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P38792 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:0718A7ABF42E9B9B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q12149 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1782|uniprotkb:Q6B280|uniprotkb:D6W267|ensemblfungi:YOR001W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp6_yeast(display_long)|uniprotkb:RRP6(gene name)|psi-mi:RRP6(display_short)|uniprotkb:UNC733(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 6(gene name synonym)|uniprotkb:YOR001W(locus name) psi-mi:"MI:0114"(x-ray crystallography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166258|imex:IM-24580-1|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_014643.1|sgd:S000005527|dip:DIP-4560N|ensemblfungi:YOR001W(gene)|ensemblfungi:YOR001W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071028"(nuclear mRNA surveillance)|mint:Q12149|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|rcsb pdb:1M0Y|rcsb pdb:2HBJ|rcsb pdb:2HBK|rcsb pdb:2HBL|rcsb pdb:2HBM|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5C0Y|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:B19A0B2ED74C6DA7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:29oQaOEcqYSzOIn7B6hj29GvisU559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - sufficient binding region:122-518 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12149 uniprotkb:P46948 intact:EBI-1782|uniprotkb:Q6B280|uniprotkb:D6W267|ensemblfungi:YOR001W intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W psi-mi:rrp6_yeast(display_long)|uniprotkb:RRP6(gene name)|psi-mi:RRP6(display_short)|uniprotkb:UNC733(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 6(gene name synonym)|uniprotkb:YOR001W(locus name) psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166316|imex:IM-24580-3|dip:DIP-16684E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014643.1|sgd:S000005527|dip:DIP-4560N|ensemblfungi:YOR001W(gene)|ensemblfungi:YOR001W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071028"(nuclear mRNA surveillance)|mint:Q12149|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|rcsb pdb:1M0Y|rcsb pdb:2HBJ|rcsb pdb:2HBK|rcsb pdb:2HBL|rcsb pdb:2HBM|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5C0Y|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:B19A0B2ED74C6DA7 crc64:C80EFFB528A43044 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:29oQaOEcqYSzOIn7B6hj29GvisU559292 rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292 rigid:y25quJ4cLdaqwH1rBp78oQsCBZo false sufficient binding region:122-518|cyan fluorescent protein tag:n-n enhanced yellow fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P38801 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1909|uniprotkb:D3DL32|ensemblfungi:YHR081W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:lrp1_yeast(display_long)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:Like an rRNA processing protein 1(gene name synonym)|uniprotkb:rRNA processing protein 47(gene name synonym)|uniprotkb:RRP47(gene name synonym)|uniprotkb:YC1D(gene name synonym)|uniprotkb:Yeast C1D domain-containing protein(gene name synonym)|uniprotkb:YHR081W(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011949.1|sgd:S000001123|dip:DIP-4359N|mint:P38801|ensemblfungi:YHR081W(gene)|ensemblfungi:YHR081W_mRNA(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1901917"(regulation of exoribonuclease activity)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:27D00668C296CC9A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:cQaT2zPsTCZHkLjuYBNF012Ym38559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P48240 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1749|uniprotkb:D6VUT8|ensemblfungi:YGR158C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:mtr3_yeast(display_long)|uniprotkb:MTR3(gene name)|psi-mi:MTR3(display_short)|uniprotkb:YGR158C(locus name)|uniprotkb:G6676(orf name)|uniprotkb:mRNA transport regulator 3(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000003390|refseq:NP_011674.3|dip:DIP-931N|mint:P48240|ensemblfungi:YGR158C(gene)|ensemblfungi:YGR158C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:2FA07ABB4A1115E0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:t5M0E3avqoJ0dbM51kE3fZlz2pc559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q08285 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1831|ensemblfungi:YOL142W|uniprotkb:D6W1S7|uniprotkb:E9P8Z4 psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp40_yeast(display_long)|uniprotkb:RRP40(gene name)|psi-mi:RRP40(display_short)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:YOL142W(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_014499.2|sgd:S000005502|ensemblfungi:YOL142W(gene)|ensemblfungi:YOL142W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030145"(manganese ion binding)|dip:DIP-5330N|mint:Q08285|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|interpro:IPR041054|rcsb pdb:2JA9|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:62B3A30348BBAA7C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:3sdpWE2qP6cVgcD2b8VDWV0ox4g559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P46948 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:C80EFFB528A43044 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q12277 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1765|uniprotkb:D6VRN9|ensemblfungi:YDL111C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp42_yeast(display_long)|uniprotkb:RRP42(gene name)|psi-mi:RRP42(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:YDL111C(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_010172.1|sgd:S000002269|dip:DIP-1463N|mint:Q12277|ensemblfungi:YDL111C(gene)|ensemblfungi:YDL111C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:806C60979642C67E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:OVyAr6b3ECMjQj3nUsuxXZqxt1o559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P25359 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1773|uniprotkb:Q8NKJ5|ensemblfungi:YCR035C|uniprotkb:D6VR45 psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp43_yeast(display_long)|uniprotkb:RRP43(gene name)|psi-mi:RRP43(display_short)|uniprotkb:YCR035C(locus name)|uniprotkb:YCR35C(orf name)|uniprotkb:YCR522(orf name)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 ensemblfungi:YCR035C(gene)|ensemblfungi:YCR035C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|refseq:NP_009964.2|sgd:S000000631|dip:DIP-5485N|mint:P25359|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:8801837B8184134D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:htGDTlKKMq7OdwcfGUKgfWCjJ1k559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q08162 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1740|uniprotkb:D6W244|ensemblfungi:YOL021C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp44_yeast(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Chromosome disjunction protein 3(gene name synonym)|uniprotkb:RRP44(gene name synonym)|uniprotkb:O2197(orf name)|uniprotkb:YOL021C(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000005381|refseq:NP_014621.1|dip:DIP-2355N|mint:Q08162|ensemblfungi:YOL021C(gene)|ensemblfungi:YOL021C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR022967|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|rcsb pdb:2VNU|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:00DD31BD2D6904F4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:YpToZNRenOPYsPJdGKEWBLsc4zA559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q05636 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1810|uniprotkb:D6VSR0|ensemblfungi:YDR280W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp45_yeast(display_long)|uniprotkb:RRP45(gene name)|psi-mi:RRP45(display_short)|uniprotkb:YDR280W(locus name)|uniprotkb:D9954.1(orf name)|uniprotkb:Ribosomal RNA-processing protein 45(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_010566.1|sgd:S000002688|dip:DIP-2084N|mint:Q05636|ensemblfungi:YDR280W(gene)|ensemblfungi:YDR280W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:65C9DB5A63678F2D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:LCdt9Nm8j2AD6iecBI2CGCrhEhQ559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P53256 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1842|uniprotkb:Q6TQU1|uniprotkb:D6VUM7|ensemblfungi:YGR095C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp46_yeast(display_long)|uniprotkb:RRP46(gene name)|psi-mi:RRP46(display_short)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:YGR095C(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011609.2|sgd:S000003327|dip:DIP-6838N|mint:P53256|ensemblfungi:YGR095C(gene)|ensemblfungi:YGR095C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:F1307E0EE4FC3133 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:2ESxObCiXUjTEvlB5ow7eCgivz0559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P38792 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:0718A7ABF42E9B9B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q12149 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1782|uniprotkb:Q6B280|uniprotkb:D6W267|ensemblfungi:YOR001W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp6_yeast(display_long)|uniprotkb:RRP6(gene name)|psi-mi:RRP6(display_short)|uniprotkb:UNC733(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 6(gene name synonym)|uniprotkb:YOR001W(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166287|imex:IM-24580-2|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_014643.1|sgd:S000005527|dip:DIP-4560N|ensemblfungi:YOR001W(gene)|ensemblfungi:YOR001W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071028"(nuclear mRNA surveillance)|mint:Q12149|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|rcsb pdb:1M0Y|rcsb pdb:2HBJ|rcsb pdb:2HBK|rcsb pdb:2HBL|rcsb pdb:2HBM|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5C0Y|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:B19A0B2ED74C6DA7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:29oQaOEcqYSzOIn7B6hj29GvisU559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - sufficient binding region:122-518 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P38801 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1909|uniprotkb:D3DL32|ensemblfungi:YHR081W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:lrp1_yeast(display_long)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:Like an rRNA processing protein 1(gene name synonym)|uniprotkb:rRNA processing protein 47(gene name synonym)|uniprotkb:RRP47(gene name synonym)|uniprotkb:YC1D(gene name synonym)|uniprotkb:Yeast C1D domain-containing protein(gene name synonym)|uniprotkb:YHR081W(locus name) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011949.1|sgd:S000001123|dip:DIP-4359N|mint:P38801|ensemblfungi:YHR081W(gene)|ensemblfungi:YHR081W_mRNA(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1901917"(regulation of exoribonuclease activity)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:27D00668C296CC9A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:cQaT2zPsTCZHkLjuYBNF012Ym38559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P48240 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1749|uniprotkb:D6VUT8|ensemblfungi:YGR158C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:mtr3_yeast(display_long)|uniprotkb:MTR3(gene name)|psi-mi:MTR3(display_short)|uniprotkb:YGR158C(locus name)|uniprotkb:G6676(orf name)|uniprotkb:mRNA transport regulator 3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000003390|refseq:NP_011674.3|dip:DIP-931N|mint:P48240|ensemblfungi:YGR158C(gene)|ensemblfungi:YGR158C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:2FA07ABB4A1115E0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:t5M0E3avqoJ0dbM51kE3fZlz2pc559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q08285 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1831|ensemblfungi:YOL142W|uniprotkb:D6W1S7|uniprotkb:E9P8Z4 psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp40_yeast(display_long)|uniprotkb:RRP40(gene name)|psi-mi:RRP40(display_short)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:YOL142W(locus name) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_014499.2|sgd:S000005502|ensemblfungi:YOL142W(gene)|ensemblfungi:YOL142W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030145"(manganese ion binding)|dip:DIP-5330N|mint:Q08285|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|interpro:IPR041054|rcsb pdb:2JA9|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:62B3A30348BBAA7C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:3sdpWE2qP6cVgcD2b8VDWV0ox4g559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P46948 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:C80EFFB528A43044 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q12277 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1765|uniprotkb:D6VRN9|ensemblfungi:YDL111C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp42_yeast(display_long)|uniprotkb:RRP42(gene name)|psi-mi:RRP42(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:YDL111C(locus name) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_010172.1|sgd:S000002269|dip:DIP-1463N|mint:Q12277|ensemblfungi:YDL111C(gene)|ensemblfungi:YDL111C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:806C60979642C67E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:OVyAr6b3ECMjQj3nUsuxXZqxt1o559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P25359 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1773|uniprotkb:Q8NKJ5|ensemblfungi:YCR035C|uniprotkb:D6VR45 psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp43_yeast(display_long)|uniprotkb:RRP43(gene name)|psi-mi:RRP43(display_short)|uniprotkb:YCR035C(locus name)|uniprotkb:YCR35C(orf name)|uniprotkb:YCR522(orf name)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 ensemblfungi:YCR035C(gene)|ensemblfungi:YCR035C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|refseq:NP_009964.2|sgd:S000000631|dip:DIP-5485N|mint:P25359|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:8801837B8184134D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:htGDTlKKMq7OdwcfGUKgfWCjJ1k559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q08162 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1740|uniprotkb:D6W244|ensemblfungi:YOL021C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp44_yeast(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Chromosome disjunction protein 3(gene name synonym)|uniprotkb:RRP44(gene name synonym)|uniprotkb:O2197(orf name)|uniprotkb:YOL021C(locus name) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 sgd:S000005381|refseq:NP_014621.1|dip:DIP-2355N|mint:Q08162|ensemblfungi:YOL021C(gene)|ensemblfungi:YOL021C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR022967|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|rcsb pdb:2VNU|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:00DD31BD2D6904F4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:YpToZNRenOPYsPJdGKEWBLsc4zA559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q05636 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1810|uniprotkb:D6VSR0|ensemblfungi:YDR280W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp45_yeast(display_long)|uniprotkb:RRP45(gene name)|psi-mi:RRP45(display_short)|uniprotkb:YDR280W(locus name)|uniprotkb:D9954.1(orf name)|uniprotkb:Ribosomal RNA-processing protein 45(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_010566.1|sgd:S000002688|dip:DIP-2084N|mint:Q05636|ensemblfungi:YDR280W(gene)|ensemblfungi:YDR280W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:65C9DB5A63678F2D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:LCdt9Nm8j2AD6iecBI2CGCrhEhQ559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P53256 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1842|uniprotkb:Q6TQU1|uniprotkb:D6VUM7|ensemblfungi:YGR095C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp46_yeast(display_long)|uniprotkb:RRP46(gene name)|psi-mi:RRP46(display_short)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:YGR095C(locus name) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011609.2|sgd:S000003327|dip:DIP-6838N|mint:P53256|ensemblfungi:YGR095C(gene)|ensemblfungi:YGR095C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:F1307E0EE4FC3133 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:2ESxObCiXUjTEvlB5ow7eCgivz0559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:P38792 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:0718A7ABF42E9B9B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53859 uniprotkb:Q12149 intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W intact:EBI-1782|uniprotkb:Q6B280|uniprotkb:D6W267|ensemblfungi:YOR001W psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym) psi-mi:rrp6_yeast(display_long)|uniprotkb:RRP6(gene name)|psi-mi:RRP6(display_short)|uniprotkb:UNC733(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 6(gene name synonym)|uniprotkb:YOR001W(locus name) psi-mi:"MI:0071"(molecular sieving) Makino et al. (2015) pubmed:26222026|doi:10.1038/nature14865|imex:IM-24580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16166339|imex:IM-24580-4|dip:DIP-199260E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226 refseq:NP_014643.1|sgd:S000005527|dip:DIP-4560N|ensemblfungi:YOR001W(gene)|ensemblfungi:YOR001W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071028"(nuclear mRNA surveillance)|mint:Q12149|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|rcsb pdb:1M0Y|rcsb pdb:2HBJ|rcsb pdb:2HBK|rcsb pdb:2HBL|rcsb pdb:2HBM|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5C0Y|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226 psi-mi:"MI:0465"(dip) crc64:52D3416EA183583B crc64:B19A0B2ED74C6DA7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292 rogid:29oQaOEcqYSzOIn7B6hj29GvisU559292 rigid:3BSBLtyi71KQKGW9lrrVJwAq2jo false - sufficient binding region:122-518 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)