#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q05791	uniprotkb:P32481	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165950|imex:IM-24945-2|dip:DIP-12143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:61CCC9DCEAFA1197	crc64:D498AE62BC3E81CD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:vj5h35F0RhctGk/zfahkcL6F8MI	false	sufficient binding region:1-291	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32481	uniprotkb:Q9P7N5	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	intact:EBI-16165908|ensemblfungi:"SPAP27G11.03.1:pep"	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:cd123_schpo(display_long)|uniprotkb:cdc123(gene name)|psi-mi:cdc123(display_short)|uniprotkb:SPAP27G11.03(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165931|imex:IM-24945-1|dip:DIP-199965E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	ensemblfungi:SPAP27G11.03(gene)|ensemblfungi:SPAP27G11.03.1(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009772(D123)|rcsb pdb:4ZGN|rcsb pdb:4ZGO|rcsb pdb:4ZGP|rcsb pdb:4ZGQ|dip:DIP-61798N|refseq:NP_593407.1	psi-mi:"MI:0465"(dip)	crc64:D498AE62BC3E81CD	crc64:352B195577263030	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rogid:2OwlvP+ZrUjJqsiNP4LK2UaHqm4284812	rigid:SGZEXxn0cvaDDqOzUERHdc0FaHc	false	sufficient binding region:410-527	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32481	uniprotkb:Q9P7N5	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	intact:EBI-16165908|ensemblfungi:"SPAP27G11.03.1:pep"	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:cd123_schpo(display_long)|uniprotkb:cdc123(gene name)|psi-mi:cdc123(display_short)|uniprotkb:SPAP27G11.03(orf name)	psi-mi:"MI:0826"(x ray scattering)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166004|imex:IM-24945-5|dip:DIP-199965E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	ensemblfungi:SPAP27G11.03(gene)|ensemblfungi:SPAP27G11.03.1(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009772(D123)|rcsb pdb:4ZGN|rcsb pdb:4ZGO|rcsb pdb:4ZGP|rcsb pdb:4ZGQ|dip:DIP-61798N|refseq:NP_593407.1	psi-mi:"MI:0465"(dip)	crc64:D498AE62BC3E81CD	crc64:352B195577263030	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rogid:2OwlvP+ZrUjJqsiNP4LK2UaHqm4284812	rigid:SGZEXxn0cvaDDqOzUERHdc0FaHc	false	sufficient binding region:410-527	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09064	uniprotkb:P32481	intact:EBI-8920|ensemblfungi:YPL237W|uniprotkb:Q6B200|uniprotkb:D6W3D3	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:if2b_yeast(display_long)|uniprotkb:YPL237W(locus name)|uniprotkb:SUI3(gene name)|psi-mi:SUI3(display_short)|uniprotkb:TIF212(gene name synonym)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166023|imex:IM-24945-6|dip:DIP-82264E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPL237W(gene)|ensemblfungi:YPL237W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72649|refseq:NP_015087.1|sgd:S000006158|reactome:R-SCE-156827|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|dip:DIP-2310N|reactome:R-SCE-381042	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:34DE9323876CEE95	crc64:D498AE62BC3E81CD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:64fjjpMNrNM6gZW2BzacUQWRC1I559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:BAlh9DGJ9TpXNaaIGeCm53Kjq0U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32481	uniprotkb:Q9P7N5	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	intact:EBI-16165908|ensemblfungi:"SPAP27G11.03.1:pep"	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:cd123_schpo(display_long)|uniprotkb:cdc123(gene name)|psi-mi:cdc123(display_short)|uniprotkb:SPAP27G11.03(orf name)	psi-mi:"MI:0071"(molecular sieving)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165985|imex:IM-24945-4|dip:DIP-199965E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	ensemblfungi:SPAP27G11.03(gene)|ensemblfungi:SPAP27G11.03.1(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009772(D123)|rcsb pdb:4ZGN|rcsb pdb:4ZGO|rcsb pdb:4ZGP|rcsb pdb:4ZGQ|dip:DIP-61798N|refseq:NP_593407.1	psi-mi:"MI:0465"(dip)	crc64:D498AE62BC3E81CD	crc64:352B195577263030	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rogid:2OwlvP+ZrUjJqsiNP4LK2UaHqm4284812	rigid:SGZEXxn0cvaDDqOzUERHdc0FaHc	false	sufficient binding region:410-527	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q05791	uniprotkb:Q05791	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165969|imex:IM-24945-3|dip:DIP-199966E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	psi-mi:"MI:0465"(dip)	crc64:61CCC9DCEAFA1197	crc64:61CCC9DCEAFA1197	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rigid:0LHbMINzbzDh0DxafdQMJSZIG1c	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20459	uniprotkb:P32481	intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166040|imex:IM-24945-7|dip:DIP-13844E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:AF4F1C80303A4E98	crc64:D498AE62BC3E81CD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:9/iGImP9/c8HSYwgmItME27z7lE559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:0MSWuuRq1JwOXqX7MFNIobbhrX4	false	-	necessary binding region:325-331	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05791	uniprotkb:P32481	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166080|imex:IM-24945-9|dip:DIP-12143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:61CCC9DCEAFA1197	crc64:D498AE62BC3E81CD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:vj5h35F0RhctGk/zfahkcL6F8MI	false	flag tag:c-c|sufficient binding region:1-291|mutation decreasing interaction strength:268-268,267-267,266-266	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32481	uniprotkb:Q9P7N5	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	intact:EBI-16165908|ensemblfungi:"SPAP27G11.03.1:pep"	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:cd123_schpo(display_long)|uniprotkb:cdc123(gene name)|psi-mi:cdc123(display_short)|uniprotkb:SPAP27G11.03(orf name)	psi-mi:"MI:0096"(pull down)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166059|imex:IM-24945-8|dip:DIP-199965E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	ensemblfungi:SPAP27G11.03(gene)|ensemblfungi:SPAP27G11.03.1(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009772(D123)|rcsb pdb:4ZGN|rcsb pdb:4ZGO|rcsb pdb:4ZGP|rcsb pdb:4ZGQ|dip:DIP-61798N|refseq:NP_593407.1	psi-mi:"MI:0465"(dip)	crc64:D498AE62BC3E81CD	crc64:352B195577263030	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rogid:2OwlvP+ZrUjJqsiNP4LK2UaHqm4284812	rigid:SGZEXxn0cvaDDqOzUERHdc0FaHc	false	sufficient binding region:410-527	his tag:n-n	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P20459	uniprotkb:P32481	intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166106|imex:IM-24945-10|dip:DIP-13844E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:AF4F1C80303A4E98	crc64:D498AE62BC3E81CD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:9/iGImP9/c8HSYwgmItME27z7lE559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:0MSWuuRq1JwOXqX7MFNIobbhrX4	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q05791	uniprotkb:P32481	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166147|imex:IM-24945-12|dip:DIP-12143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:61CCC9DCEAFA1197	crc64:D498AE62BC3E81CD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:vj5h35F0RhctGk/zfahkcL6F8MI	false	-	sufficient binding region:410-527	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q05791	uniprotkb:P20459	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166125|imex:IM-24945-11|dip:DIP-199967E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N	psi-mi:"MI:0465"(dip)	crc64:61CCC9DCEAFA1197	crc64:AF4F1C80303A4E98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rogid:9/iGImP9/c8HSYwgmItME27z7lE559292	rigid:PN6UhNDdVHmepjz1U1aDVgzaYzk	false	flag tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q05791	uniprotkb:P32481	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166125|imex:IM-24945-11|dip:DIP-199967E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:61CCC9DCEAFA1197	crc64:D498AE62BC3E81CD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:PN6UhNDdVHmepjz1U1aDVgzaYzk	false	flag tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q05791	uniprotkb:P32481	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166166|imex:IM-24945-13|dip:DIP-12143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:61CCC9DCEAFA1197	crc64:D498AE62BC3E81CD	comment:Deletion of region 325-331 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:vj5h35F0RhctGk/zfahkcL6F8MI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05791	uniprotkb:P32481	intact:EBI-34676|uniprotkb:D6VYL6|ensemblfungi:YLR215C	intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4	psi-mi:cd123_yeast(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:YLR215C(locus name)	psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Panvert et al. (2015)	pubmed:26211610|doi:10.1016/j.str.2015.06.014|imex:IM-24945	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16166184|imex:IM-24945-14|dip:DIP-12143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013316.1|sgd:S000004205|mint:Q05791|dip:DIP-1886N|ensemblfungi:YLR215C(gene)|ensemblfungi:YLR215C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)	rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N	psi-mi:"MI:0465"(dip)	crc64:61CCC9DCEAFA1197	crc64:D498AE62BC3E81CD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:0l5atnXXuNolF2MPjJf2TWhrVKA559292	rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292	rigid:vj5h35F0RhctGk/zfahkcL6F8MI	false	-	sufficient binding region:410-527	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)