#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:A3DCU1	uniprotkb:A3DCU1	intact:EBI-16165623|ensemblbacteria:ABN51770	intact:EBI-16165623|ensemblbacteria:ABN51770	psi-mi:a3dcu1_acet2(display_long)|uniprotkb:Cthe_0534(locus name)	psi-mi:a3dcu1_acet2(display_long)|uniprotkb:Cthe_0534(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Lin et al. (2015)	pubmed:26201595|doi:10.1038/nature14623|imex:IM-24590	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165643|imex:IM-24590-1|dip:DIP-199270E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABN51770(transcript)|ensemblbacteria:Cthe_0534(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043214"(ABC-type bacteriocin transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005074(Peptidase C39, bacteriocin processing)|interpro:IPR005897(Peptidase C39, ABC-type bacteriocin transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR036640|interpro:IPR039421|rcsb pdb:4RY2|rcsb pdb:4S0F|rcsb pdb:6V9Z|interpro:IPR027417|refseq:WP_011837864.1|dip:DIP-61598N	ensemblbacteria:ABN51770(transcript)|ensemblbacteria:Cthe_0534(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043214"(ABC-type bacteriocin transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005074(Peptidase C39, bacteriocin processing)|interpro:IPR005897(Peptidase C39, ABC-type bacteriocin transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR036640|interpro:IPR039421|rcsb pdb:4RY2|rcsb pdb:4S0F|rcsb pdb:6V9Z|interpro:IPR027417|refseq:WP_011837864.1|dip:DIP-61598N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:knC6SJbNB8nNz15uv/jX6SajEEs203119	rogid:knC6SJbNB8nNz15uv/jX6SajEEs203119	rigid:xNbLVPmzMCyOwVOAXpkQdgsrLmo	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A3DCU2	uniprotkb:A3DCU1	intact:EBI-16165659|ensemblbacteria:ABN51771	intact:EBI-16165623|ensemblbacteria:ABN51770	psi-mi:a3dcu2_acet2(display_long)|uniprotkb:Cthe_0535(locus name)	psi-mi:a3dcu1_acet2(display_long)|uniprotkb:Cthe_0534(locus name)	psi-mi:"MI:0096"(pull down)	Lin et al. (2015)	pubmed:26201595|doi:10.1038/nature14623|imex:IM-24590	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165691|imex:IM-24590-3|dip:DIP-199271E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABN51771(transcript)|ensemblbacteria:Cthe_0535(gene)|rcsb pdb:6V9Z|refseq:WP_003517578.1|dip:DIP-61599N	ensemblbacteria:ABN51770(transcript)|ensemblbacteria:Cthe_0534(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043214"(ABC-type bacteriocin transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005074(Peptidase C39, bacteriocin processing)|interpro:IPR005897(Peptidase C39, ABC-type bacteriocin transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR036640|interpro:IPR039421|rcsb pdb:4RY2|rcsb pdb:4S0F|rcsb pdb:6V9Z|interpro:IPR027417|refseq:WP_011837864.1|dip:DIP-61598N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:MazMjxN1FRm/mIbvB+PetYvzK2Y203119	rogid:knC6SJbNB8nNz15uv/jX6SajEEs203119	rigid:JYwZRs6KH56pU6E4iEVqajMaAmQ	false	-	sufficient binding region:1-148|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:A3DCU2	uniprotkb:A3DCU1	intact:EBI-16165659|ensemblbacteria:ABN51771	intact:EBI-16165623|ensemblbacteria:ABN51770	psi-mi:a3dcu2_acet2(display_long)|uniprotkb:Cthe_0535(locus name)	psi-mi:a3dcu1_acet2(display_long)|uniprotkb:Cthe_0534(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lin et al. (2015)	pubmed:26201595|doi:10.1038/nature14623|imex:IM-24590	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165712|imex:IM-24590-4|dip:DIP-199271E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABN51771(transcript)|ensemblbacteria:Cthe_0535(gene)|rcsb pdb:6V9Z|refseq:WP_003517578.1|dip:DIP-61599N	ensemblbacteria:ABN51770(transcript)|ensemblbacteria:Cthe_0534(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043214"(ABC-type bacteriocin transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005074(Peptidase C39, bacteriocin processing)|interpro:IPR005897(Peptidase C39, ABC-type bacteriocin transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR036640|interpro:IPR039421|rcsb pdb:4RY2|rcsb pdb:4S0F|rcsb pdb:6V9Z|interpro:IPR027417|refseq:WP_011837864.1|dip:DIP-61598N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:MazMjxN1FRm/mIbvB+PetYvzK2Y203119	rogid:knC6SJbNB8nNz15uv/jX6SajEEs203119	rigid:JYwZRs6KH56pU6E4iEVqajMaAmQ	false	flag tag:c-c	sufficient binding region:1-148	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:A3DCU2	uniprotkb:A3DCU1	intact:EBI-16165659|ensemblbacteria:ABN51771	intact:EBI-16165623|ensemblbacteria:ABN51770	psi-mi:a3dcu2_acet2(display_long)|uniprotkb:Cthe_0535(locus name)	psi-mi:a3dcu1_acet2(display_long)|uniprotkb:Cthe_0534(locus name)	psi-mi:"MI:0435"(protease assay)	Lin et al. (2015)	pubmed:26201595|doi:10.1038/nature14623|imex:IM-24590	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165666|imex:IM-24590-2|dip:DIP-199271E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABN51771(transcript)|ensemblbacteria:Cthe_0535(gene)|rcsb pdb:6V9Z|refseq:WP_003517578.1|dip:DIP-61599N	ensemblbacteria:ABN51770(transcript)|ensemblbacteria:Cthe_0534(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043214"(ABC-type bacteriocin transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005074(Peptidase C39, bacteriocin processing)|interpro:IPR005897(Peptidase C39, ABC-type bacteriocin transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR036640|interpro:IPR039421|rcsb pdb:4RY2|rcsb pdb:4S0F|rcsb pdb:6V9Z|interpro:IPR027417|refseq:WP_011837864.1|dip:DIP-61598N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:MazMjxN1FRm/mIbvB+PetYvzK2Y203119	rogid:knC6SJbNB8nNz15uv/jX6SajEEs203119	rigid:JYwZRs6KH56pU6E4iEVqajMaAmQ	false	-	sufficient binding region:1-148|mutation disrupting interaction rate:21-21|mutation decreasing interaction rate:99-99	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:A3DCU2	uniprotkb:A3DCU1	intact:EBI-16165659|ensemblbacteria:ABN51771	intact:EBI-16165623|ensemblbacteria:ABN51770	psi-mi:a3dcu2_acet2(display_long)|uniprotkb:Cthe_0535(locus name)	psi-mi:a3dcu1_acet2(display_long)|uniprotkb:Cthe_0534(locus name)	psi-mi:"MI:0880"(atpase assay)	Lin et al. (2015)	pubmed:26201595|doi:10.1038/nature14623|imex:IM-24590	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	taxid:203119(cloth)|taxid:203119("Clostridium thermocellum (strain ATCC 27405 / DSM 1237)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16165733|imex:IM-24590-5|dip:DIP-199271E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABN51771(transcript)|ensemblbacteria:Cthe_0535(gene)|rcsb pdb:6V9Z|refseq:WP_003517578.1|dip:DIP-61599N	ensemblbacteria:ABN51770(transcript)|ensemblbacteria:Cthe_0534(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043214"(ABC-type bacteriocin transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005074(Peptidase C39, bacteriocin processing)|interpro:IPR005897(Peptidase C39, ABC-type bacteriocin transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR036640|interpro:IPR039421|rcsb pdb:4RY2|rcsb pdb:4S0F|rcsb pdb:6V9Z|interpro:IPR027417|refseq:WP_011837864.1|dip:DIP-61598N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:MazMjxN1FRm/mIbvB+PetYvzK2Y203119	rogid:knC6SJbNB8nNz15uv/jX6SajEEs203119	rigid:JYwZRs6KH56pU6E4iEVqajMaAmQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)