#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O43173 uniprotkb:O43173 intact:EBI-16165155|ensembl:ENSP00000320431|uniprotkb:A8K0F2|uniprotkb:Q6B085|uniprotkb:Q9NS41 intact:EBI-16165155|ensembl:ENSP00000320431|uniprotkb:A8K0F2|uniprotkb:Q6B085|uniprotkb:Q9NS41 psi-mi:sia8c_human(display_long)|uniprotkb:ST8SIA3(gene name)|psi-mi:ST8SIA3(display_short)|uniprotkb:SIAT8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase 8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase III(gene name synonym)|uniprotkb:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3(gene name synonym)|uniprotkb:Sialyltransferase 8C(gene name synonym)|uniprotkb:Sialyltransferase St8Sia III(gene name synonym) psi-mi:sia8c_human(display_long)|uniprotkb:ST8SIA3(gene name)|psi-mi:ST8SIA3(display_short)|uniprotkb:SIAT8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase 8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase III(gene name synonym)|uniprotkb:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3(gene name synonym)|uniprotkb:Sialyltransferase 8C(gene name synonym)|uniprotkb:Sialyltransferase St8Sia III(gene name synonym) psi-mi:"MI:0104"(static light scattering) Volkers et al. (2015) pubmed:26192331|doi:10.1038/nsmb.3060|imex:IM-24762 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16165195|imex:IM-24762-1|dip:DIP-199670E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177511(gene)|ensembl:ENST00000324000(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001574"(ganglioside biosynthetic process)|go:"GO:0003828"(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1990743"(protein sialylation)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|interpro:IPR038578|rcsb pdb:5BO6|rcsb pdb:5BO7|rcsb pdb:5BO8|rcsb pdb:5BO9|rcsb pdb:5CXY|reactome:R-HSA-4085001|reactome:R-HSA-975577|refseq:NP_056963.2|dip:DIP-61706N ensembl:ENSG00000177511(gene)|ensembl:ENST00000324000(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001574"(ganglioside biosynthetic process)|go:"GO:0003828"(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1990743"(protein sialylation)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|interpro:IPR038578|rcsb pdb:5BO6|rcsb pdb:5BO7|rcsb pdb:5BO8|rcsb pdb:5BO9|rcsb pdb:5CXY|reactome:R-HSA-4085001|reactome:R-HSA-975577|refseq:NP_056963.2|dip:DIP-61706N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/08 2017/08/10 rogid:3Ov74DyMtgbDFb0EFKB4o/kh29A9606 rogid:3Ov74DyMtgbDFb0EFKB4o/kh29A9606 rigid:XIjpDuJMhxQMVC0Rh9I6PEgVpVI false sufficient binding region:61-380 sufficient binding region:61-380 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43173 uniprotkb:O43173 intact:EBI-16165155|ensembl:ENSP00000320431|uniprotkb:A8K0F2|uniprotkb:Q6B085|uniprotkb:Q9NS41 intact:EBI-16165155|ensembl:ENSP00000320431|uniprotkb:A8K0F2|uniprotkb:Q6B085|uniprotkb:Q9NS41 psi-mi:sia8c_human(display_long)|uniprotkb:ST8SIA3(gene name)|psi-mi:ST8SIA3(display_short)|uniprotkb:SIAT8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase 8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase III(gene name synonym)|uniprotkb:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3(gene name synonym)|uniprotkb:Sialyltransferase 8C(gene name synonym)|uniprotkb:Sialyltransferase St8Sia III(gene name synonym) psi-mi:sia8c_human(display_long)|uniprotkb:ST8SIA3(gene name)|psi-mi:ST8SIA3(display_short)|uniprotkb:SIAT8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase 8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase III(gene name synonym)|uniprotkb:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3(gene name synonym)|uniprotkb:Sialyltransferase 8C(gene name synonym)|uniprotkb:Sialyltransferase St8Sia III(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Volkers et al. (2015) pubmed:26192331|doi:10.1038/nsmb.3060|imex:IM-24762 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16165235|imex:IM-24762-3|dip:DIP-199670E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177511(gene)|ensembl:ENST00000324000(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001574"(ganglioside biosynthetic process)|go:"GO:0003828"(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1990743"(protein sialylation)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|interpro:IPR038578|rcsb pdb:5BO6|rcsb pdb:5BO7|rcsb pdb:5BO8|rcsb pdb:5BO9|rcsb pdb:5CXY|reactome:R-HSA-4085001|reactome:R-HSA-975577|refseq:NP_056963.2|dip:DIP-61706N ensembl:ENSG00000177511(gene)|ensembl:ENST00000324000(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001574"(ganglioside biosynthetic process)|go:"GO:0003828"(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1990743"(protein sialylation)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|interpro:IPR038578|rcsb pdb:5BO6|rcsb pdb:5BO7|rcsb pdb:5BO8|rcsb pdb:5BO9|rcsb pdb:5CXY|reactome:R-HSA-4085001|reactome:R-HSA-975577|refseq:NP_056963.2|dip:DIP-61706N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/08 2017/08/10 rogid:3Ov74DyMtgbDFb0EFKB4o/kh29A9606 rogid:3Ov74DyMtgbDFb0EFKB4o/kh29A9606 rigid:XIjpDuJMhxQMVC0Rh9I6PEgVpVI false sufficient binding region:81-380 sufficient binding region:81-380 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43173 uniprotkb:O43173 intact:EBI-16165155|ensembl:ENSP00000320431|uniprotkb:A8K0F2|uniprotkb:Q6B085|uniprotkb:Q9NS41 intact:EBI-16165155|ensembl:ENSP00000320431|uniprotkb:A8K0F2|uniprotkb:Q6B085|uniprotkb:Q9NS41 psi-mi:sia8c_human(display_long)|uniprotkb:ST8SIA3(gene name)|psi-mi:ST8SIA3(display_short)|uniprotkb:SIAT8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase 8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase III(gene name synonym)|uniprotkb:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3(gene name synonym)|uniprotkb:Sialyltransferase 8C(gene name synonym)|uniprotkb:Sialyltransferase St8Sia III(gene name synonym) psi-mi:sia8c_human(display_long)|uniprotkb:ST8SIA3(gene name)|psi-mi:ST8SIA3(display_short)|uniprotkb:SIAT8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase 8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase III(gene name synonym)|uniprotkb:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3(gene name synonym)|uniprotkb:Sialyltransferase 8C(gene name synonym)|uniprotkb:Sialyltransferase St8Sia III(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Volkers et al. (2015) pubmed:26192331|doi:10.1038/nsmb.3060|imex:IM-24762 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16165214|imex:IM-24762-2|dip:DIP-199670E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177511(gene)|ensembl:ENST00000324000(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001574"(ganglioside biosynthetic process)|go:"GO:0003828"(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1990743"(protein sialylation)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|interpro:IPR038578|rcsb pdb:5BO6|rcsb pdb:5BO7|rcsb pdb:5BO8|rcsb pdb:5BO9|rcsb pdb:5CXY|reactome:R-HSA-4085001|reactome:R-HSA-975577|refseq:NP_056963.2|dip:DIP-61706N ensembl:ENSG00000177511(gene)|ensembl:ENST00000324000(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001574"(ganglioside biosynthetic process)|go:"GO:0003828"(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1990743"(protein sialylation)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|interpro:IPR038578|rcsb pdb:5BO6|rcsb pdb:5BO7|rcsb pdb:5BO8|rcsb pdb:5BO9|rcsb pdb:5CXY|reactome:R-HSA-4085001|reactome:R-HSA-975577|refseq:NP_056963.2|dip:DIP-61706N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/08 2017/08/10 rogid:3Ov74DyMtgbDFb0EFKB4o/kh29A9606 rogid:3Ov74DyMtgbDFb0EFKB4o/kh29A9606 rigid:XIjpDuJMhxQMVC0Rh9I6PEgVpVI false sufficient binding region:61-380 sufficient binding region:61-380 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43173 uniprotkb:O43173 intact:EBI-16165155|ensembl:ENSP00000320431|uniprotkb:A8K0F2|uniprotkb:Q6B085|uniprotkb:Q9NS41 intact:EBI-16165155|ensembl:ENSP00000320431|uniprotkb:A8K0F2|uniprotkb:Q6B085|uniprotkb:Q9NS41 psi-mi:sia8c_human(display_long)|uniprotkb:ST8SIA3(gene name)|psi-mi:ST8SIA3(display_short)|uniprotkb:SIAT8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase 8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase III(gene name synonym)|uniprotkb:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3(gene name synonym)|uniprotkb:Sialyltransferase 8C(gene name synonym)|uniprotkb:Sialyltransferase St8Sia III(gene name synonym) psi-mi:sia8c_human(display_long)|uniprotkb:ST8SIA3(gene name)|psi-mi:ST8SIA3(display_short)|uniprotkb:SIAT8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase 8C(gene name synonym)|uniprotkb:Alpha-2,8-sialyltransferase III(gene name synonym)|uniprotkb:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3(gene name synonym)|uniprotkb:Sialyltransferase 8C(gene name synonym)|uniprotkb:Sialyltransferase St8Sia III(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Volkers et al. (2015) pubmed:26192331|doi:10.1038/nsmb.3060|imex:IM-24762 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16165253|imex:IM-24762-4|dip:DIP-199670E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177511(gene)|ensembl:ENST00000324000(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001574"(ganglioside biosynthetic process)|go:"GO:0003828"(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1990743"(protein sialylation)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|interpro:IPR038578|rcsb pdb:5BO6|rcsb pdb:5BO7|rcsb pdb:5BO8|rcsb pdb:5BO9|rcsb pdb:5CXY|reactome:R-HSA-4085001|reactome:R-HSA-975577|refseq:NP_056963.2|dip:DIP-61706N ensembl:ENSG00000177511(gene)|ensembl:ENST00000324000(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001574"(ganglioside biosynthetic process)|go:"GO:0003828"(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006688"(glycosphingolipid biosynthetic process)|go:"GO:0008373"(sialyltransferase activity)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1990743"(protein sialylation)|interpro:IPR001675(Glycosyl transferase, family 29)|interpro:IPR012163(Sialyltransferase)|interpro:IPR038578|rcsb pdb:5BO6|rcsb pdb:5BO7|rcsb pdb:5BO8|rcsb pdb:5BO9|rcsb pdb:5CXY|reactome:R-HSA-4085001|reactome:R-HSA-975577|refseq:NP_056963.2|dip:DIP-61706N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/08 2017/08/10 rogid:3Ov74DyMtgbDFb0EFKB4o/kh29A9606 rogid:3Ov74DyMtgbDFb0EFKB4o/kh29A9606 rigid:XIjpDuJMhxQMVC0Rh9I6PEgVpVI false sufficient binding region:61-380 sufficient binding region:61-380 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)