#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15397 uniprotkb:P19532 intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3 intact:EBI-1048957|uniprotkb:A8MZL6|uniprotkb:Q92757|uniprotkb:Q92758|uniprotkb:Q99964|uniprotkb:Q5JU74|intact:EBI-28988974|ensembl:ENSP00000314129 psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym) psi-mi:tfe3_human(display_long)|uniprotkb:TFE3(gene name)|psi-mi:TFE3(display_short)|uniprotkb:BHLHE33(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 33(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Perera et al. (2015) pubmed:26168401|doi:10.1038/nature14587|imex:IM-24583 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16165043|imex:IM-24583-1|dip:DIP-199262E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N refseq:NP_006512.2|refseq:NP_001269071.1|ensembl:ENSP00000314129|ensembl:ENST00000493583|ensembl:ENSP00000476976|ensembl:ENSG00000068323(gene)|ensembl:ENST00000315869(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR021802|interpro:IPR024100|interpro:IPR031867|interpro:IPR036638|dip:DIP-50187N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606 rogid:AQ735wtDaKEzjMlG6ZyiOBVo/kw9606 rigid:cpYrLLSye/31sETwNsX+sDg6sl4 false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15397 uniprotkb:P19532 intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3 intact:EBI-1048957|uniprotkb:A8MZL6|uniprotkb:Q92757|uniprotkb:Q92758|uniprotkb:Q99964|uniprotkb:Q5JU74|intact:EBI-28988974|ensembl:ENSP00000314129 psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym) psi-mi:tfe3_human(display_long)|uniprotkb:TFE3(gene name)|psi-mi:TFE3(display_short)|uniprotkb:BHLHE33(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 33(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Perera et al. (2015) pubmed:26168401|doi:10.1038/nature14587|imex:IM-24583 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16165062|imex:IM-24583-2|dip:DIP-199262E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N refseq:NP_006512.2|refseq:NP_001269071.1|ensembl:ENSP00000314129|ensembl:ENST00000493583|ensembl:ENSP00000476976|ensembl:ENSG00000068323(gene)|ensembl:ENST00000315869(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR021802|interpro:IPR024100|interpro:IPR031867|interpro:IPR036638|dip:DIP-50187N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606 rogid:AQ735wtDaKEzjMlG6ZyiOBVo/kw9606 rigid:cpYrLLSye/31sETwNsX+sDg6sl4 false - flag tag:n-n - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)