#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O14777	uniprotkb:P33981-1	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-15986834|ensembl:ENSP00000358813	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ji et al. (2015)	pubmed:26068854|doi:10.1126/science.aaa4029|imex:IM-24667	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16161171|imex:IM-24667-1|dip:DIP-199408E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rigid:22C+JWtY3nFO33OcceabeTC4piY	false	-	sufficient binding region:1-62|sufficient binding region:201-300|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O14777	uniprotkb:P33981-1	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-15986834|ensembl:ENSP00000358813	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ji et al. (2015)	pubmed:26068854|doi:10.1126/science.aaa4029|imex:IM-24667	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16161194|imex:IM-24667-2|dip:DIP-199408E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rigid:22C+JWtY3nFO33OcceabeTC4piY	false	mutation decreasing interaction strength:89-89|mutation decreasing interaction strength:166-166|mutation decreasing interaction strength:89-89,166-166|glutathione s tranferase tag:n-n	sufficient binding region:1-200	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14777	uniprotkb:P33981-1	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-15986834|ensembl:ENSP00000358813	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ji et al. (2015)	pubmed:26068854|doi:10.1126/science.aaa4029|imex:IM-24667	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16161225|imex:IM-24667-3|dip:DIP-199408E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rigid:22C+JWtY3nFO33OcceabeTC4piY	false	-	sufficient binding region:1-517|strep tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P33981-1	uniprotkb:Q9HBM1	intact:EBI-15986834|ensembl:ENSP00000358813	intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ji et al. (2015)	pubmed:26068854|doi:10.1126/science.aaa4029|imex:IM-24667	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16161246|imex:IM-24667-4|dip:DIP-199409E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606	rigid:hxek4Goku/RMM8lR/pHeUEttWUY	false	sufficient binding region:261-300	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P33981-1	uniprotkb:Q8NBT2	intact:EBI-15986834|ensembl:ENSP00000358813	intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)	psi-mi:"MI:0096"(pull down)	Ji et al. (2015)	pubmed:26068854|doi:10.1126/science.aaa4029|imex:IM-24667	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16161246|imex:IM-24667-4|dip:DIP-199409E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606	rigid:hxek4Goku/RMM8lR/pHeUEttWUY	false	sufficient binding region:261-300	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P33981-1	uniprotkb:Q9BZD4	intact:EBI-15986834|ensembl:ENSP00000358813	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ji et al. (2015)	pubmed:26068854|doi:10.1126/science.aaa4029|imex:IM-24667	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16161246|imex:IM-24667-4|dip:DIP-199409E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	rigid:hxek4Goku/RMM8lR/pHeUEttWUY	false	sufficient binding region:261-300	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P33981-1	uniprotkb:O14777	intact:EBI-15986834|ensembl:ENSP00000358813	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ji et al. (2015)	pubmed:26068854|doi:10.1126/science.aaa4029|imex:IM-24667	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16161246|imex:IM-24667-4|dip:DIP-199409E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rigid:hxek4Goku/RMM8lR/pHeUEttWUY	false	sufficient binding region:261-300	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q9BZD4	uniprotkb:P33981-1	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	intact:EBI-15986834|ensembl:ENSP00000358813	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ji et al. (2015)	pubmed:26068854|doi:10.1126/science.aaa4029|imex:IM-24667	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16161276|imex:IM-24667-5|dip:DIP-199410E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rigid:74yQvEBKFtQFGKk/xv8TVjSG5Qg	false	35s radiolabel:?-?|mutation disrupting interaction strength:7-7,6-6|mutation decreasing interaction strength:103-103|mutation decreasing interaction strength:115-115|mutation decreasing interaction strength:116-116|mutation disrupting interaction strength:126-126|mutation decreasing interaction strength:129-129	sufficient binding region:261-300	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)