#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UM47	uniprotkb:Q9UM47	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:"MI:0028"(cosedimentation in solution)	Xu et al. (2015)	pubmed:26051713|doi:10.1016/j.str.2015.05.001|imex:IM-24557	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16160055|imex:IM-24557-1|dip:DIP-199179E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802	refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rigid:6fam1oYmzt1Kb6xNWACAjaEv2aQ	false	sufficient binding region:1378-1640	sufficient binding region:1378-1640	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UM47	uniprotkb:Q9UM47	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Xu et al. (2015)	pubmed:26051713|doi:10.1016/j.str.2015.05.001|imex:IM-24557	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16160074|imex:IM-24557-2|dip:DIP-199179E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802	refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rigid:6fam1oYmzt1Kb6xNWACAjaEv2aQ	false	sufficient binding region:1378-1640	sufficient binding region:1378-1640	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)