#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P91349 uniprotkb:P91349 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157547|imex:IM-24659-4|dip:DIP-133123E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:VipdS7tdis7JiNs7BWyCQrbi8MY false green fluorescent protein tag:c-c green fluorescent protein tag:c-c - 0 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P34331 uniprotkb:P91349 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157528|imex:IM-24659-3|dip:DIP-199385E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:FhYt3DjhwWFJVzaGnijuB+3ASzw false - green fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P91349 uniprotkb:P91349 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157510|imex:IM-24659-2|dip:DIP-133123E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:VipdS7tdis7JiNs7BWyCQrbi8MY false red fluorescent protein tag:c-c red fluorescent protein tag:c-c - 0 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P91349 uniprotkb:P91349 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0410"(3D electron microscopy) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157494|imex:IM-24659-1|dip:DIP-133123E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:VipdS7tdis7JiNs7BWyCQrbi8MY false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34331 uniprotkb:P91349 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0424"(protein kinase assay) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157627|imex:IM-24659-8|dip:DIP-199385E - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:FhYt3DjhwWFJVzaGnijuB+3ASzw false - mutation disrupting interaction rate:530-530|O-phospho-L-serine:530-530 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P91870 uniprotkb:P91349 intact:EBI-320962|ensemblmetazoa:F32H2.3.1|ensemblmetazoa:F32H2.3.2 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:spd2_caeel(display_long)|uniprotkb:F32H2.3(orf name)|uniprotkb:spd-2(gene name)|psi-mi:spd-2(display_short) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157607|imex:IM-24659-7|dip:DIP-133055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492414.1|wormbase:F32H2.3|ensemblmetazoa:F32H2.3.1(transcript)|ensemblmetazoa:F32H2.3.2(transcript)|ensemblmetazoa:WBGene00004953(gene)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019901"(protein kinase binding)|go:"GO:0040025"(vulval development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR039103|dip:DIP-25500N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GBGtZRHVbrFLFhWQy/m9+L17Etk6239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:szpeIV+G7aEvZvL4C+Vz006YE4U false - green fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34331 uniprotkb:P91349 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157586|imex:IM-24659-6|dip:DIP-199385E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:FhYt3DjhwWFJVzaGnijuB+3ASzw false green fluorescent protein tag:c-c red fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:G5EEM5 uniprotkb:P91349 intact:EBI-320102|ensemblmetazoa:F22B5.7.1 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:zyg9_caeel(display_long)|uniprotkb:zyg-9(gene name)|psi-mi:zyg-9(display_short)|uniprotkb:F22B5.7(orf name) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157565|imex:IM-24659-5|dip:DIP-199386E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:NP_495784.1|uniprotkb:O61442(uniprot-removed-ac)|rcsb pdb:2OF3|wormbase:F22B5.7|ensemblmetazoa:WBGene00006994(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051231"(spindle elongation)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:F22B5.7.1(transcript)|interpro:IPR034085|interpro:IPR029632 refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:d5IkZ+B1AcKT1ZE2uWfbBzd9p5U6239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:JYcNgrMvyO4rcwx8+gIhBik3KI0 false green fluorescent protein tag:c-c red fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P91870 uniprotkb:P91349 intact:EBI-320962|ensemblmetazoa:F32H2.3.1|ensemblmetazoa:F32H2.3.2 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:spd2_caeel(display_long)|uniprotkb:F32H2.3(orf name)|uniprotkb:spd-2(gene name)|psi-mi:spd-2(display_short) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Woodruff et al. (2015) pubmed:25977552|doi:10.1126/science.aaa3923|imex:IM-24659 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16157649|imex:IM-24659-9|dip:DIP-133055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492414.1|wormbase:F32H2.3|ensemblmetazoa:F32H2.3.1(transcript)|ensemblmetazoa:F32H2.3.2(transcript)|ensemblmetazoa:WBGene00004953(gene)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019901"(protein kinase binding)|go:"GO:0040025"(vulval development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR039103|dip:DIP-25500N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GBGtZRHVbrFLFhWQy/m9+L17Etk6239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rigid:szpeIV+G7aEvZvL4C+Vz006YE4U false green fluorescent protein tag:n-n red fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)