#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43563	uniprotkb:P53894	intact:EBI-11125|ensemblfungi:YFL034C-B|uniprotkb:D6VTJ5	intact:EBI-4110|uniprotkb:D6W122|ensemblfungi:YNL161W	psi-mi:mob2_yeast(display_long)|uniprotkb:YFL035C(orf name)|uniprotkb:YFL035C-A(orf name)|uniprotkb:YFL034C-B(locus name)|uniprotkb:MOB2(gene name)|psi-mi:MOB2(display_short)|uniprotkb:MPS1 binder 2(gene name synonym)|uniprotkb:Maintenance of ploidy protein MOB2(gene name synonym)	psi-mi:cbk1_yeast(display_long)|uniprotkb:CBK1(gene name)|psi-mi:CBK1(display_short)|uniprotkb:YNL161W(locus name)|uniprotkb:N1727(orf name)|uniprotkb:Cell wall biosynthesis kinase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Gógl et al. (2015)	pubmed:25966461|doi:10.1371/journal.pbio.1002146|imex:IM-24394	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16157345|imex:IM-24394-1|dip:DIP-11597E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007049"(cell cycle)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043332"(mating projection tip)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|rcsb pdb:4LQP|rcsb pdb:4LQQ|rcsb pdb:4LQS|rcsb pdb:5NCL|ensemblfungi:YFL034C-B(gene)|rcsb pdb:5NCM|ensemblfungi:YFL034C-B_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|reactome:R-SCE-2028269|refseq:NP_116618.1|sgd:S000001859|dip:DIP-1449N	sgd:S000005105|refseq:NP_014238.3|dip:DIP-5656N|ensemblfungi:YNL161W(gene)|ensemblfungi:YNL161W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4LQP|rcsb pdb:4LQQ|rcsb pdb:4LQS|rcsb pdb:5NCL|rcsb pdb:5NCM	psi-mi:"MI:0465"(dip)	crc64:CFBA15FF83BFAA33	crc64:87EBCD2C3C96EE11	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:UHuaOd4GWnEGpu7qD+EmIUiKs5k559292	rogid:pNqqn26/5iKdHk4g9hhRcrOSMa0559292	rigid:SNAI1qMEtUNPurQSEHmzOh8BNS8	false	sufficient binding region:45-287	sufficient binding region:251-756	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53894	uniprotkb:P24276	intact:EBI-4110|uniprotkb:D6W122|ensemblfungi:YNL161W	intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C	psi-mi:cbk1_yeast(display_long)|uniprotkb:CBK1(gene name)|psi-mi:CBK1(display_short)|uniprotkb:YNL161W(locus name)|uniprotkb:N1727(orf name)|uniprotkb:Cell wall biosynthesis kinase(gene name synonym)	psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gógl et al. (2015)	pubmed:25966461|doi:10.1371/journal.pbio.1002146|imex:IM-24394	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16157366|imex:IM-24394-2|dip:DIP-11602E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005105|refseq:NP_014238.3|dip:DIP-5656N|ensemblfungi:YNL161W(gene)|ensemblfungi:YNL161W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4LQP|rcsb pdb:4LQQ|rcsb pdb:4LQS|rcsb pdb:5NCL|rcsb pdb:5NCM	refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276	psi-mi:"MI:0465"(dip)	crc64:87EBCD2C3C96EE11	crc64:3D50FD6838ECA514	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pNqqn26/5iKdHk4g9hhRcrOSMa0559292	rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292	rigid:BoNejuteVp/RZEb/OOSuP9gms5Q	false	sufficient binding region:352-756	sufficient binding region:211-214|sufficient binding region:234-238|mutation disrupting interaction strength:211-211|mutation disrupting interaction strength:211-211|mutation disrupting interaction strength:212-212|mutation disrupting interaction strength:213-213|mutation disrupting interaction strength:213-213|mutation disrupting interaction strength:214-214|mutation disrupting interaction strength:212-212|maltose binding protein tag:n-n|mutation disrupting interaction strength:212-212|mutation disrupting interaction strength:212-212|mutation disrupting interaction strength:212-212|mutation disrupting interaction strength:212-212|mutation disrupting interaction strength:212-212|mutation disrupting interaction strength:213-213	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53894	uniprotkb:P24276	intact:EBI-4110|uniprotkb:D6W122|ensemblfungi:YNL161W	intact:EBI-18153|uniprotkb:D6VSS2|ensemblfungi:YDR293C	psi-mi:cbk1_yeast(display_long)|uniprotkb:CBK1(gene name)|psi-mi:CBK1(display_short)|uniprotkb:YNL161W(locus name)|uniprotkb:N1727(orf name)|uniprotkb:Cell wall biosynthesis kinase(gene name synonym)	psi-mi:ssd1_yeast(display_long)|uniprotkb:SSD1(gene name)|psi-mi:SSD1(display_short)|uniprotkb:CLA1(gene name synonym)|uniprotkb:RLD1(gene name synonym)|uniprotkb:SRK1(gene name synonym)|uniprotkb:YDR293C(locus name)|uniprotkb:D9819.4(orf name)|uniprotkb:Protein SRK1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gógl et al. (2015)	pubmed:25966461|doi:10.1371/journal.pbio.1002146|imex:IM-24394	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16157422|imex:IM-24394-3|dip:DIP-11602E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005105|refseq:NP_014238.3|dip:DIP-5656N|ensemblfungi:YNL161W(gene)|ensemblfungi:YNL161W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4LQP|rcsb pdb:4LQQ|rcsb pdb:4LQS|rcsb pdb:5NCL|rcsb pdb:5NCM	refseq:NP_010579.1|sgd:S000002701|ensemblfungi:YDR293C(gene)|ensemblfungi:YDR293C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051301"(cell division)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:1903450"(regulation of G1 to G0 transition)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR041093|interpro:IPR041505|rcsb pdb:5NCL|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|dip:DIP-6449N|mint:P24276	psi-mi:"MI:0465"(dip)	crc64:87EBCD2C3C96EE11	crc64:3D50FD6838ECA514	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pNqqn26/5iKdHk4g9hhRcrOSMa0559292	rogid:myt8+lnu2/li6TuGiM5GBfMtUiw559292	rigid:BoNejuteVp/RZEb/OOSuP9gms5Q	false	sufficient binding region:352-756|mutation disrupting interaction strength:687-687	maltose binding protein tag:n-n|sufficient binding region:208-214	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P21192	uniprotkb:P53894	intact:EBI-2073|uniprotkb:D6VYC6|ensemblfungi:YLR131C	intact:EBI-4110|uniprotkb:D6W122|ensemblfungi:YNL161W	psi-mi:ace2_yeast(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:L3123(orf name)|uniprotkb:L9606.10(orf name)|uniprotkb:YLR131C(locus name)	psi-mi:cbk1_yeast(display_long)|uniprotkb:CBK1(gene name)|psi-mi:CBK1(display_short)|uniprotkb:YNL161W(locus name)|uniprotkb:N1727(orf name)|uniprotkb:Cell wall biosynthesis kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gógl et al. (2015)	pubmed:25966461|doi:10.1371/journal.pbio.1002146|imex:IM-24394	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16157448|imex:IM-24394-4|dip:DIP-87797E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013232.1|sgd:S000004121|dip:DIP-2012N|mint:P21192|ensemblfungi:YLR131C(gene)|ensemblfungi:YLR131C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060196"(positive regulation of antisense RNA transcription)|go:"GO:2001043"(positive regulation of septum digestion after cytokinesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	sgd:S000005105|refseq:NP_014238.3|dip:DIP-5656N|ensemblfungi:YNL161W(gene)|ensemblfungi:YNL161W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4LQP|rcsb pdb:4LQQ|rcsb pdb:4LQS|rcsb pdb:5NCL|rcsb pdb:5NCM	psi-mi:"MI:0465"(dip)	crc64:A7FCA8C506A2FD75	crc64:87EBCD2C3C96EE11	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:iOLMyumnA219VIBA9AXaZd9NI0c559292	rogid:pNqqn26/5iKdHk4g9hhRcrOSMa0559292	rigid:wf8f9yo/fWlghgI/o1r+6kc2apA	false	sufficient binding region:272-286|maltose binding protein tag:n-n|mutation decreasing interaction strength:272-272|mutation decreasing interaction strength:277-277|mutation disrupting interaction strength:283-283|mutation disrupting interaction strength:285-285|mutation disrupting interaction strength:286-286	sufficient binding region:251-756	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)