#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P9WI73 uniprotkb:P9WI73 intact:EBI-6405537|uniprotkb:P65728|uniprotkb:P96256|uniprotkb:L0T3M0 intact:EBI-6405537|uniprotkb:P65728|uniprotkb:P96256|uniprotkb:L0T3M0 psi-mi:pkng_myctu(display_long)|uniprotkb:MTCY22G10.06c(orf name)|uniprotkb:Rv0410c(locus name)|uniprotkb:pknG(gene name)|psi-mi:pknG(display_short) psi-mi:pkng_myctu(display_long)|uniprotkb:MTCY22G10.06c(orf name)|uniprotkb:Rv0410c(locus name)|uniprotkb:pknG(gene name)|psi-mi:pknG(display_short) psi-mi:"MI:0424"(protein kinase assay) Lisa et al. (2015) pubmed:25960409|doi:10.1016/j.str.2015.04.001|imex:IM-24549 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16156475|imex:IM-24549-1|dip:DIP-196996E - - psi-mi:"MI:0898"(putative self) psi-mi:"MI:0898"(putative self) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052064"(induction by symbiont of defense-related host reactive oxygen species production)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:4Y0X|rcsb pdb:4Y12|interpro:IPR031634|interpro:IPR031636|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_003402100.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2PZI|refseq:NP_214924.1 go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052064"(induction by symbiont of defense-related host reactive oxygen species production)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:4Y0X|rcsb pdb:4Y12|interpro:IPR031634|interpro:IPR031636|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_003402100.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2PZI|refseq:NP_214924.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:urqDW6tue2zYS1stGgPCx4f0M1w83332 rogid:urqDW6tue2zYS1stGgPCx4f0M1w83332 rigid:FbAB8fm/mBURPjx4vvAY2bOSv1c false sufficient binding region:1-405 sufficient binding region:1-405 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WJA9 uniprotkb:P9WI73 intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606 intact:EBI-6405537|uniprotkb:P65728|uniprotkb:P96256|uniprotkb:L0T3M0 psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short) psi-mi:pkng_myctu(display_long)|uniprotkb:MTCY22G10.06c(orf name)|uniprotkb:Rv0410c(locus name)|uniprotkb:pknG(gene name)|psi-mi:pknG(display_short) psi-mi:"MI:0424"(protein kinase assay) Lisa et al. (2015) pubmed:25960409|doi:10.1016/j.str.2015.04.001|imex:IM-24549 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16156493|imex:IM-24549-2|dip:DIP-199172E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1 go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052064"(induction by symbiont of defense-related host reactive oxygen species production)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:4Y0X|rcsb pdb:4Y12|interpro:IPR031634|interpro:IPR031636|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_003402100.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2PZI|refseq:NP_214924.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332 rogid:urqDW6tue2zYS1stGgPCx4f0M1w83332 rigid:9370vq+bQPcxKyIL7RRdM+uWOPg false sufficient binding region:44-162 sufficient binding region:138-750|sufficient binding region:1-405 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WJA9 uniprotkb:P9WI73 intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606 intact:EBI-6405537|uniprotkb:P65728|uniprotkb:P96256|uniprotkb:L0T3M0 psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short) psi-mi:pkng_myctu(display_long)|uniprotkb:MTCY22G10.06c(orf name)|uniprotkb:Rv0410c(locus name)|uniprotkb:pknG(gene name)|psi-mi:pknG(display_short) psi-mi:"MI:0424"(protein kinase assay) Lisa et al. (2015) pubmed:25960409|doi:10.1016/j.str.2015.04.001|imex:IM-24549 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16156516|imex:IM-24549-3|dip:DIP-199172E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1 go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052064"(induction by symbiont of defense-related host reactive oxygen species production)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:4Y0X|rcsb pdb:4Y12|interpro:IPR031634|interpro:IPR031636|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_003402100.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2PZI|refseq:NP_214924.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332 rogid:urqDW6tue2zYS1stGgPCx4f0M1w83332 rigid:9370vq+bQPcxKyIL7RRdM+uWOPg false sufficient binding region:14-30 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)