#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P46821-PRO_0000018605 uniprotkb:Q8IZU9 intact:EBI-9517186 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:p46821-pro_0000018605(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427310|imex:IM-26159-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-764611(chain-parent) ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - chain-seq-start:2207|chain-seq-end:2468 - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:EHAGDbUkDRzW31qBdagt4ZkHYHs9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:TgOmH94WxSzLL+NF3rg9WqKtsd8 false - sufficient binding region:1-517 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y6X6 uniprotkb:Q8IZU9 intact:EBI-310686|uniprotkb:A8MTX3|uniprotkb:Q5VYX4|uniprotkb:Q5VYX5|uniprotkb:Q5VYX6|uniprotkb:Q6ZS13|uniprotkb:Q8N3C2|uniprotkb:Q8N948|uniprotkb:A6H8Y0|ensembl:ENSP00000349145 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:myo16_human(display_long)|uniprotkb:MYO16(gene name)|psi-mi:MYO16(display_short)|uniprotkb:KIAA0865(gene name synonym)|uniprotkb:Unconventional myosin-16(gene name synonym)|uniprotkb:MYO16B(gene name synonym)|uniprotkb:NYAP3(gene name synonym)|uniprotkb:Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427358|imex:IM-26159-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055826.1|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036042|interpro:IPR036770|interpro:IPR039482|ensembl:ENSG00000041515(gene)|ensembl:ENST00000356711(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016459"(myosin complex)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_011519364.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:no figure i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:INONhfPhUiHS26nbST/jfSib1t89606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:f8q7CTitCc/fGXK1DhP+xgEwQfM false - sufficient binding region:1-517 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P05026 uniprotkb:Q8IZU9 intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427364|imex:IM-26159-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:no figure ii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:QutaSTLc4kjrbbRRpx8m3NCRKno false - sufficient binding region:545-766 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3C8 uniprotkb:Q8IZU9 intact:EBI-1045733|uniprotkb:Q5VTX1|uniprotkb:Q549X0|uniprotkb:Q9BS96|uniprotkb:Q9P009|uniprotkb:D3DVF9|uniprotkb:A8K9R1|ensembl:ENSP00000356982 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:ufc1_human(display_long)|uniprotkb:UFC1(gene name)|psi-mi:UFC1(display_short)|uniprotkb:CGI-126(orf name)|uniprotkb:HSPC155(orf name) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427370|imex:IM-26159-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057490.2|ensembl:ENSG00000143222(gene)|ensembl:ENST00000368003(transcript)|go:"GO:0007420"(brain development)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061657"(UFM1 conjugating enzyme activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071568"(UFM1 transferase activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR014806(Protein of unknown function DUF1782)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2K07|rcsb pdb:2Z6O|rcsb pdb:2Z6P|rcsb pdb:3EVX|refseq:XP_016856939.1|refseq:XP_016856940.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:no figure iii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:qM6IH1SjQcAXszcGGqin8bLe4Pk9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:z5xNmnjD738tkU9GpD/jZbmSBWU false - sufficient binding region:545-766 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34897 uniprotkb:Q8IZU9 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427376|imex:IM-26159-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:no figure iv|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:87rwY85sNcMt4aEXqdYuFsKzjr4 false - sufficient binding region:545-766 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46821-PRO_0000018605 uniprotkb:Q8IZU9 intact:EBI-9517186 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:p46821-pro_0000018605(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427438|imex:IM-26159-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-764611(chain-parent) ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - chain-seq-start:2207|chain-seq-end:2468 - figure legend:Figure 3A1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/10/06 2017/10/17 rogid:EHAGDbUkDRzW31qBdagt4ZkHYHs9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:TgOmH94WxSzLL+NF3rg9WqKtsd8 false flag tag:n-n v5 tag:c-c|his tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y6X6 uniprotkb:Q8IZU9 intact:EBI-310686|uniprotkb:A8MTX3|uniprotkb:Q5VYX4|uniprotkb:Q5VYX5|uniprotkb:Q5VYX6|uniprotkb:Q6ZS13|uniprotkb:Q8N3C2|uniprotkb:Q8N948|uniprotkb:A6H8Y0|ensembl:ENSP00000349145 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:myo16_human(display_long)|uniprotkb:MYO16(gene name)|psi-mi:MYO16(display_short)|uniprotkb:KIAA0865(gene name synonym)|uniprotkb:Unconventional myosin-16(gene name synonym)|uniprotkb:MYO16B(gene name synonym)|uniprotkb:NYAP3(gene name synonym)|uniprotkb:Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427472|imex:IM-26159-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055826.1|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036042|interpro:IPR036770|interpro:IPR039482|ensembl:ENSG00000041515(gene)|ensembl:ENST00000356711(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016459"(myosin complex)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_011519364.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:Figure 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/10/06 2017/10/17 rogid:INONhfPhUiHS26nbST/jfSib1t89606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:f8q7CTitCc/fGXK1DhP+xgEwQfM false green fluorescent protein tag:n-n v5 tag:c-c|his tag:c-c|sufficient binding region:1-517 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P05026 uniprotkb:Q8IZU9 intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427494|imex:IM-26159-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:Figure 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/10/06 2017/10/17 rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:QutaSTLc4kjrbbRRpx8m3NCRKno false flag tag:n-n v5 tag:c-c|his tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y3C8 uniprotkb:Q8IZU9 intact:EBI-1045733|uniprotkb:Q5VTX1|uniprotkb:Q549X0|uniprotkb:Q9BS96|uniprotkb:Q9P009|uniprotkb:D3DVF9|uniprotkb:A8K9R1|ensembl:ENSP00000356982 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:ufc1_human(display_long)|uniprotkb:UFC1(gene name)|psi-mi:UFC1(display_short)|uniprotkb:CGI-126(orf name)|uniprotkb:HSPC155(orf name) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427506|imex:IM-26159-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057490.2|ensembl:ENSG00000143222(gene)|ensembl:ENST00000368003(transcript)|go:"GO:0007420"(brain development)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061657"(UFM1 conjugating enzyme activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071568"(UFM1 transferase activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR014806(Protein of unknown function DUF1782)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2K07|rcsb pdb:2Z6O|rcsb pdb:2Z6P|rcsb pdb:3EVX|refseq:XP_016856939.1|refseq:XP_016856940.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:Figure 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/10/06 2017/10/17 rogid:qM6IH1SjQcAXszcGGqin8bLe4Pk9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:z5xNmnjD738tkU9GpD/jZbmSBWU false flag tag:n-n v5 tag:c-c|his tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P34897 uniprotkb:Q8IZU9 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427518|imex:IM-26159-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:Figure 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/10/06 2017/10/17 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:87rwY85sNcMt4aEXqdYuFsKzjr4 false flag tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P14873-PRO_0000018607 uniprotkb:Q8IZU9 intact:EBI-16427461 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:p14873-pro_0000018607(display_long)|uniprotkb:"MAP1(X)"(gene name synonym)|uniprotkb:MAP1.2(gene name synonym)|uniprotkb:Map1b(gene name)|psi-mi:Map1b(display_short)|uniprotkb:Mtap1b(gene name synonym)|uniprotkb:Mtap5(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427450|imex:IM-26159-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-764653(chain-parent) ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - chain-seq-start:2203|chain-seq-end:2464 - figure legend:Figure 3A2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)") - 2017/10/06 2017/10/17 rogid:TIRptxenbb+oPZMkRCwMxbIY1oI10090 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:cjSmcjBrDLNa10RLVFvGhwn2gg0 false - v5 tag:c-c|his tag:c-c|sufficient binding region:1-517 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P34897 uniprotkb:Q8IZU9 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427389|imex:IM-26159-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:Figure 2H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:87rwY85sNcMt4aEXqdYuFsKzjr4 false - sufficient binding region:545-766 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05026 uniprotkb:Q8IZU9 intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427407|imex:IM-26159-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:Figure 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:QutaSTLc4kjrbbRRpx8m3NCRKno false - sufficient binding region:545-766 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46821-PRO_0000018605 uniprotkb:Q8IZU9 intact:EBI-9517186 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:p46821-pro_0000018605(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427395|imex:IM-26159-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-764611(chain-parent) ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - chain-seq-start:2207|chain-seq-end:2468 - figure legend:Figure 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:EHAGDbUkDRzW31qBdagt4ZkHYHs9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:TgOmH94WxSzLL+NF3rg9WqKtsd8 false - sufficient binding region:1-517 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6X6 uniprotkb:Q8IZU9 intact:EBI-310686|uniprotkb:A8MTX3|uniprotkb:Q5VYX4|uniprotkb:Q5VYX5|uniprotkb:Q5VYX6|uniprotkb:Q6ZS13|uniprotkb:Q8N3C2|uniprotkb:Q8N948|uniprotkb:A6H8Y0|ensembl:ENSP00000349145 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:myo16_human(display_long)|uniprotkb:MYO16(gene name)|psi-mi:MYO16(display_short)|uniprotkb:KIAA0865(gene name synonym)|uniprotkb:Unconventional myosin-16(gene name synonym)|uniprotkb:MYO16B(gene name synonym)|uniprotkb:NYAP3(gene name synonym)|uniprotkb:Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427401|imex:IM-26159-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055826.1|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036042|interpro:IPR036770|interpro:IPR039482|ensembl:ENSG00000041515(gene)|ensembl:ENST00000356711(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016459"(myosin complex)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_011519364.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:Figure 2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:INONhfPhUiHS26nbST/jfSib1t89606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:f8q7CTitCc/fGXK1DhP+xgEwQfM false - sufficient binding region:1-517 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3C8 uniprotkb:Q8IZU9 intact:EBI-1045733|uniprotkb:Q5VTX1|uniprotkb:Q549X0|uniprotkb:Q9BS96|uniprotkb:Q9P009|uniprotkb:D3DVF9|uniprotkb:A8K9R1|ensembl:ENSP00000356982 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:ufc1_human(display_long)|uniprotkb:UFC1(gene name)|psi-mi:UFC1(display_short)|uniprotkb:CGI-126(orf name)|uniprotkb:HSPC155(orf name) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16427413|imex:IM-26159-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057490.2|ensembl:ENSG00000143222(gene)|ensembl:ENST00000368003(transcript)|go:"GO:0007420"(brain development)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061657"(UFM1 conjugating enzyme activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071568"(UFM1 transferase activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR014806(Protein of unknown function DUF1782)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2K07|rcsb pdb:2Z6O|rcsb pdb:2Z6P|rcsb pdb:3EVX|refseq:XP_016856939.1|refseq:XP_016856940.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 - - - figure legend:Figure 2G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/06 2017/10/17 rogid:qM6IH1SjQcAXszcGGqin8bLe4Pk9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:z5xNmnjD738tkU9GpD/jZbmSBWU false - sufficient binding region:545-766 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46821-PRO_0000018605 uniprotkb:Q8IZU9 intact:EBI-9517186 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:p46821-pro_0000018605(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16427555|imex:IM-26159-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-764611(chain-parent) ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 go:"GO:0043005"(neuron projection)|go:"GO:0005737"(cytoplasm) chain-seq-start:2207|chain-seq-end:2468 - figure legend:Figure 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-neuron)|taxid:10116(Rattus norvegicus neuronal cell) - 2017/10/06 2017/10/17 rogid:EHAGDbUkDRzW31qBdagt4ZkHYHs9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:TgOmH94WxSzLL+NF3rg9WqKtsd8 false flag tag:n-n v5 tag:c-c|his tag:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9Y6X6 uniprotkb:Q8IZU9 intact:EBI-310686|uniprotkb:A8MTX3|uniprotkb:Q5VYX4|uniprotkb:Q5VYX5|uniprotkb:Q5VYX6|uniprotkb:Q6ZS13|uniprotkb:Q8N3C2|uniprotkb:Q8N948|uniprotkb:A6H8Y0|ensembl:ENSP00000349145 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:myo16_human(display_long)|uniprotkb:MYO16(gene name)|psi-mi:MYO16(display_short)|uniprotkb:KIAA0865(gene name synonym)|uniprotkb:Unconventional myosin-16(gene name synonym)|uniprotkb:MYO16B(gene name synonym)|uniprotkb:NYAP3(gene name synonym)|uniprotkb:Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16427569|imex:IM-26159-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055826.1|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036042|interpro:IPR036770|interpro:IPR039482|ensembl:ENSG00000041515(gene)|ensembl:ENST00000356711(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016459"(myosin complex)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_011519364.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 go:"GO:0043005"(neuron projection)|go:"GO:0005737"(cytoplasm) - - figure legend:Figure 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-neuron)|taxid:10116(Rattus norvegicus neuronal cell) - 2017/10/06 2017/10/17 rogid:INONhfPhUiHS26nbST/jfSib1t89606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:f8q7CTitCc/fGXK1DhP+xgEwQfM false green fluorescent protein tag:n-n v5 tag:c-c|his tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P05026 uniprotkb:Q8IZU9 intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16427581|imex:IM-26159-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 go:"GO:0005737"(cytoplasm) - - figure legend:Figure 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-neuron)|taxid:10116(Rattus norvegicus neuronal cell) - 2017/10/06 2017/10/17 rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:QutaSTLc4kjrbbRRpx8m3NCRKno false flag tag:n-n v5 tag:c-c|his tag:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9Y3C8 uniprotkb:Q8IZU9 intact:EBI-1045733|uniprotkb:Q5VTX1|uniprotkb:Q549X0|uniprotkb:Q9BS96|uniprotkb:Q9P009|uniprotkb:D3DVF9|uniprotkb:A8K9R1|ensembl:ENSP00000356982 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:ufc1_human(display_long)|uniprotkb:UFC1(gene name)|psi-mi:UFC1(display_short)|uniprotkb:CGI-126(orf name)|uniprotkb:HSPC155(orf name) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16427593|imex:IM-26159-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057490.2|ensembl:ENSG00000143222(gene)|ensembl:ENST00000368003(transcript)|go:"GO:0007420"(brain development)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061657"(UFM1 conjugating enzyme activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071568"(UFM1 transferase activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR014806(Protein of unknown function DUF1782)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2K07|rcsb pdb:2Z6O|rcsb pdb:2Z6P|rcsb pdb:3EVX|refseq:XP_016856939.1|refseq:XP_016856940.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 go:"GO:0005737"(cytoplasm) - - figure legend:Figure 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-neuron)|taxid:10116(Rattus norvegicus neuronal cell) - 2017/10/06 2017/10/17 rogid:qM6IH1SjQcAXszcGGqin8bLe4Pk9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:z5xNmnjD738tkU9GpD/jZbmSBWU false flag tag:n-n v5 tag:c-c|his tag:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P34897 uniprotkb:Q8IZU9 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0 psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2014) pubmed:25902260|imex:IM-26159 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16427605|imex:IM-26159-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1 go:"GO:0043005"(neuron projection)|go:"GO:0005737"(cytoplasm) - - figure legend:Figure 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-neuron)|taxid:10116(Rattus norvegicus neuronal cell) - 2017/10/06 2017/10/17 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606 rigid:87rwY85sNcMt4aEXqdYuFsKzjr4 false flag tag:n-n v5 tag:c-c|his tag:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)