#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9XUS9 uniprotkb:G5EG83 intact:EBI-315948|ensemblmetazoa:K08E3.6.1|ensemblmetazoa:K08E3.6.2 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 psi-mi:q9xus9_caeel(display_long)|uniprotkb:cyk-4(gene name)|psi-mi:cyk-4(display_short)|uniprotkb:CELE_K08E3.6(orf name)|uniprotkb:K08E3.6(orf name) psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:"MI:0872"(atomic force microscopy) Davies et al. (2015) pubmed:25875822|doi:10.1371/journal.pbio.1002121|imex:IM-24229 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16154282|imex:IM-24229-2|dip:DIP-198777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-983189|refseq:NP_499845.1|wormbase:K08E3.6|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|ensemblmetazoa:K08E3.6.1(transcript)|ensemblmetazoa:K08E3.6.2(transcript)|ensemblmetazoa:WBGene00000875(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-25057N ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:KHkQNZBkhUbn2rQE9+8+uvbQrzo6239 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rigid:7AG3nvaKzrCMyQ+6zbuuqjmk2sk false sufficient binding region:1-120 sufficient binding region:1-601 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EG83 uniprotkb:G5EG83 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:"MI:0872"(atomic force microscopy) Davies et al. (2015) pubmed:25875822|doi:10.1371/journal.pbio.1002121|imex:IM-24229 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16154264|imex:IM-24229-1|dip:DIP-198778E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rigid:bpl+h9KaMRRwkJz9b8P8wS48P+4 false sufficient binding region:1-601 sufficient binding region:1-601 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9XUS9 uniprotkb:G5EG83 intact:EBI-315948|ensemblmetazoa:K08E3.6.1|ensemblmetazoa:K08E3.6.2 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 psi-mi:q9xus9_caeel(display_long)|uniprotkb:cyk-4(gene name)|psi-mi:cyk-4(display_short)|uniprotkb:CELE_K08E3.6(orf name)|uniprotkb:K08E3.6(orf name) psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:"MI:0096"(pull down) Davies et al. (2015) pubmed:25875822|doi:10.1371/journal.pbio.1002121|imex:IM-24229 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16154303|imex:IM-24229-3|dip:DIP-198777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-983189|refseq:NP_499845.1|wormbase:K08E3.6|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|ensemblmetazoa:K08E3.6.1(transcript)|ensemblmetazoa:K08E3.6.2(transcript)|ensemblmetazoa:WBGene00000875(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-25057N ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:KHkQNZBkhUbn2rQE9+8+uvbQrzo6239 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rigid:7AG3nvaKzrCMyQ+6zbuuqjmk2sk false sufficient binding region:1-120|glutathione s tranferase tag:n-n sufficient binding region:435-555|fusion protein:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG83 uniprotkb:G5EG83 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Davies et al. (2015) pubmed:25875822|doi:10.1371/journal.pbio.1002121|imex:IM-24229 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0465"(DIP) intact:EBI-16154328|imex:IM-24229-4|dip:DIP-198777E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rigid:7AG3nvaKzrCMyQ+6zbuuqjmk2sk false sufficient binding region:435-555|venus fluorescent protein tag:n-n sufficient binding region:435-555|venus fluorescent protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EG83 uniprotkb:Q9XUS9 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 intact:EBI-315948|ensemblmetazoa:K08E3.6.1|ensemblmetazoa:K08E3.6.2 psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:q9xus9_caeel(display_long)|uniprotkb:cyk-4(gene name)|psi-mi:cyk-4(display_short)|uniprotkb:CELE_K08E3.6(orf name)|uniprotkb:K08E3.6(orf name) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Davies et al. (2015) pubmed:25875822|doi:10.1371/journal.pbio.1002121|imex:IM-24229 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0465"(DIP) intact:EBI-16154328|imex:IM-24229-4|dip:DIP-198777E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N reactome:R-CEL-983189|refseq:NP_499845.1|wormbase:K08E3.6|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|ensemblmetazoa:K08E3.6.1(transcript)|ensemblmetazoa:K08E3.6.2(transcript)|ensemblmetazoa:WBGene00000875(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-25057N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rogid:KHkQNZBkhUbn2rQE9+8+uvbQrzo6239 rigid:7AG3nvaKzrCMyQ+6zbuuqjmk2sk false sufficient binding region:435-555|venus fluorescent protein tag:n-n sufficient binding region:1-120 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EG83 uniprotkb:G5EG83 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Davies et al. (2015) pubmed:25875822|doi:10.1371/journal.pbio.1002121|imex:IM-24229 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16154381|imex:IM-24229-6|dip:DIP-198778E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rigid:9qnJRTHNbezOy23tqmMAy1zT6sQ false sufficient binding region:435-555|venus fluorescent protein tag:n-n sufficient binding region:435-555|venus fluorescent protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9XUS9 uniprotkb:G5EG83 intact:EBI-315948|ensemblmetazoa:K08E3.6.1|ensemblmetazoa:K08E3.6.2 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 psi-mi:q9xus9_caeel(display_long)|uniprotkb:cyk-4(gene name)|psi-mi:cyk-4(display_short)|uniprotkb:CELE_K08E3.6(orf name)|uniprotkb:K08E3.6(orf name) psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:"MI:0096"(pull down) Davies et al. (2015) pubmed:25875822|doi:10.1371/journal.pbio.1002121|imex:IM-24229 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16154356|imex:IM-24229-5|dip:DIP-198777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-983189|refseq:NP_499845.1|wormbase:K08E3.6|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|ensemblmetazoa:K08E3.6.1(transcript)|ensemblmetazoa:K08E3.6.2(transcript)|ensemblmetazoa:WBGene00000875(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-25057N ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:KHkQNZBkhUbn2rQE9+8+uvbQrzo6239 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rigid:7AG3nvaKzrCMyQ+6zbuuqjmk2sk false sufficient binding region:1-120|glutathione s tranferase tag:n-n sufficient binding region:435-555|fusion protein:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9XUS9 uniprotkb:G5EG83 intact:EBI-315948|ensemblmetazoa:K08E3.6.1|ensemblmetazoa:K08E3.6.2 intact:EBI-16154228|ensemblmetazoa:M03D4.1a.1 psi-mi:q9xus9_caeel(display_long)|uniprotkb:cyk-4(gene name)|psi-mi:cyk-4(display_short)|uniprotkb:CELE_K08E3.6(orf name)|uniprotkb:K08E3.6(orf name) psi-mi:g5eg83_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:CELE_M03D4.1(orf name)|uniprotkb:M03D4.1(orf name) psi-mi:"MI:0071"(molecular sieving) Davies et al. (2015) pubmed:25875822|doi:10.1371/journal.pbio.1002121|imex:IM-24229 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16154406|imex:IM-24229-7|dip:DIP-198777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-983189|refseq:NP_499845.1|wormbase:K08E3.6|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|ensemblmetazoa:K08E3.6.1(transcript)|ensemblmetazoa:K08E3.6.2(transcript)|ensemblmetazoa:WBGene00000875(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-25057N ensemblmetazoa:M03D4.1a.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|rcsb pdb:5X3E|refseq:NP_001023309.1|wormbase:M03D4.1a|dip:DIP-61408N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:KHkQNZBkhUbn2rQE9+8+uvbQrzo6239 rogid:hkg4a8J4o2wiGcJJoOTpegWAfxU6239 rigid:7AG3nvaKzrCMyQ+6zbuuqjmk2sk false sufficient binding region:1-120 sufficient binding region:435-555 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)